[Genetics and present therapy options in Parkinson's disease: a review].
Identifieur interne : 000038 ( PubMed/Corpus ); précédent : 000037; suivant : 000039[Genetics and present therapy options in Parkinson's disease: a review].
Auteurs : Benjamin Bereznai ; Mária Judit MolnarSource :
- Ideggyógyászati szemle [ 0019-1442 ] ; 2009.
English descriptors
- KwdEn :
- Antiparkinson Agents (therapeutic use), Combined Modality Therapy (methods), Dance Therapy (MeSH), Deep Brain Stimulation (MeSH), Genetic Predisposition to Disease (MeSH), Genetic Testing (MeSH), Genetic Therapy (MeSH), Humans (MeSH), Intracellular Signaling Peptides and Proteins (genetics), Music Therapy (MeSH), Oncogene Proteins (genetics), Parkinson Disease (diagnosis), Parkinson Disease (drug therapy), Parkinson Disease (genetics), Parkinson Disease (therapy), Physical Therapy Modalities (MeSH), Protein Kinases (genetics), Protein-Serine-Threonine Kinases (genetics), Psychotherapy (MeSH), Relaxation Therapy (MeSH), Ubiquitin-Protein Ligases (genetics), alpha-Synuclein (genetics).
- MESH :
- chemical , genetics : Intracellular Signaling Peptides and Proteins, Oncogene Proteins, Protein Kinases, Protein-Serine-Threonine Kinases, Ubiquitin-Protein Ligases, alpha-Synuclein.
- chemical , therapeutic use : Antiparkinson Agents.
- diagnosis : Parkinson Disease.
- drug therapy : Parkinson Disease.
- genetics : Parkinson Disease.
- methods : Combined Modality Therapy.
- therapy : Parkinson Disease.
- Dance Therapy, Deep Brain Stimulation, Genetic Predisposition to Disease, Genetic Testing, Genetic Therapy, Humans, Music Therapy, Physical Therapy Modalities, Psychotherapy, Relaxation Therapy.
Abstract
In the past years, six monogenic forms of Parkinson disease have clearly been associated with this movement disorder. The most frequent forms are LRRK2- and Parkin-associated Parkinson disease. Currently, a genetic diagnosis does not change the therapy, the genes involved in genetic Parkinson disease help to understand the underlying pathophysiologic mechanisms of Parkinson disease. Beside the overview of the molecular-genetic basis, we give a review about genetic testing, pharmacological and other multidisciplinary treatment options.
PubMed: 19579663
Links to Exploration step
pubmed:19579663Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">[Genetics and present therapy options in Parkinson's disease: a review].</title>
<author><name sortKey="Bereznai, Benjamin" sort="Bereznai, Benjamin" uniqKey="Bereznai B" first="Benjamin" last="Bereznai">Benjamin Bereznai</name>
<affiliation><nlm:affiliation>Semmelweis Egyetem, Molekuláris Neurológiai Klinikai és Kutatási Központ, Budapest. bereznaib@neur.sote.hu</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Molnar, Maria Judit" sort="Molnar, Maria Judit" uniqKey="Molnar M" first="Mária Judit" last="Molnar">Mária Judit Molnar</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2009">2009</date>
<idno type="RBID">pubmed:19579663</idno>
<idno type="pmid">19579663</idno>
<idno type="wicri:Area/PubMed/Corpus">000038</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000038</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">[Genetics and present therapy options in Parkinson's disease: a review].</title>
<author><name sortKey="Bereznai, Benjamin" sort="Bereznai, Benjamin" uniqKey="Bereznai B" first="Benjamin" last="Bereznai">Benjamin Bereznai</name>
<affiliation><nlm:affiliation>Semmelweis Egyetem, Molekuláris Neurológiai Klinikai és Kutatási Központ, Budapest. bereznaib@neur.sote.hu</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Molnar, Maria Judit" sort="Molnar, Maria Judit" uniqKey="Molnar M" first="Mária Judit" last="Molnar">Mária Judit Molnar</name>
</author>
</analytic>
<series><title level="j">Ideggyógyászati szemle</title>
<idno type="ISSN">0019-1442</idno>
<imprint><date when="2009" type="published">2009</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antiparkinson Agents (therapeutic use)</term>
<term>Combined Modality Therapy (methods)</term>
<term>Dance Therapy (MeSH)</term>
<term>Deep Brain Stimulation (MeSH)</term>
<term>Genetic Predisposition to Disease (MeSH)</term>
<term>Genetic Testing (MeSH)</term>
<term>Genetic Therapy (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Intracellular Signaling Peptides and Proteins (genetics)</term>
<term>Music Therapy (MeSH)</term>
<term>Oncogene Proteins (genetics)</term>
<term>Parkinson Disease (diagnosis)</term>
<term>Parkinson Disease (drug therapy)</term>
<term>Parkinson Disease (genetics)</term>
<term>Parkinson Disease (therapy)</term>
<term>Physical Therapy Modalities (MeSH)</term>
<term>Protein Kinases (genetics)</term>
<term>Protein-Serine-Threonine Kinases (genetics)</term>
<term>Psychotherapy (MeSH)</term>
<term>Relaxation Therapy (MeSH)</term>
<term>Ubiquitin-Protein Ligases (genetics)</term>
<term>alpha-Synuclein (genetics)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="genetics" xml:lang="en"><term>Intracellular Signaling Peptides and Proteins</term>
<term>Oncogene Proteins</term>
<term>Protein Kinases</term>
<term>Protein-Serine-Threonine Kinases</term>
<term>Ubiquitin-Protein Ligases</term>
<term>alpha-Synuclein</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiparkinson Agents</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Combined Modality Therapy</term>
</keywords>
<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Dance Therapy</term>
<term>Deep Brain Stimulation</term>
<term>Genetic Predisposition to Disease</term>
<term>Genetic Testing</term>
<term>Genetic Therapy</term>
<term>Humans</term>
<term>Music Therapy</term>
<term>Physical Therapy Modalities</term>
<term>Psychotherapy</term>
<term>Relaxation Therapy</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">In the past years, six monogenic forms of Parkinson disease have clearly been associated with this movement disorder. The most frequent forms are LRRK2- and Parkin-associated Parkinson disease. Currently, a genetic diagnosis does not change the therapy, the genes involved in genetic Parkinson disease help to understand the underlying pathophysiologic mechanisms of Parkinson disease. Beside the overview of the molecular-genetic basis, we give a review about genetic testing, pharmacological and other multidisciplinary treatment options.</div>
</front>
</TEI>
<pubmed><MedlineCitation Owner="NLM" Status="MEDLINE"><PMID Version="1">19579663</PMID>
<DateCreated><Year>2009</Year>
<Month>07</Month>
<Day>07</Day>
</DateCreated>
<DateCompleted><Year>2009</Year>
<Month>07</Month>
<Day>23</Day>
</DateCompleted>
<DateRevised><Year>2012</Year>
<Month>11</Month>
<Day>15</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0019-1442</ISSN>
<JournalIssue CitedMedium="Print"><Volume>62</Volume>
<Issue>5-6</Issue>
<PubDate><Year>2009</Year>
<Month>May</Month>
<Day>30</Day>
</PubDate>
</JournalIssue>
<Title>Ideggyógyászati szemle</Title>
<ISOAbbreviation>Ideggyogy Sz</ISOAbbreviation>
</Journal>
<ArticleTitle>[Genetics and present therapy options in Parkinson's disease: a review].</ArticleTitle>
<Pagination><MedlinePgn>155-63</MedlinePgn>
</Pagination>
<Abstract><AbstractText>In the past years, six monogenic forms of Parkinson disease have clearly been associated with this movement disorder. The most frequent forms are LRRK2- and Parkin-associated Parkinson disease. Currently, a genetic diagnosis does not change the therapy, the genes involved in genetic Parkinson disease help to understand the underlying pathophysiologic mechanisms of Parkinson disease. Beside the overview of the molecular-genetic basis, we give a review about genetic testing, pharmacological and other multidisciplinary treatment options.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Bereznai</LastName>
<ForeName>Benjamin</ForeName>
<Initials>B</Initials>
<AffiliationInfo><Affiliation>Semmelweis Egyetem, Molekuláris Neurológiai Klinikai és Kutatási Központ, Budapest. bereznaib@neur.sote.hu</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Molnar</LastName>
<ForeName>Mária Judit</ForeName>
<Initials>MJ</Initials>
</Author>
</AuthorList>
<Language>hun</Language>
<PublicationTypeList><PublicationType UI="D004740">English Abstract</PublicationType>
<PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D016454">Review</PublicationType>
</PublicationTypeList>
<VernacularTitle>A Parkinson-kór genetikája és aktuális terápiás lehetoségei.</VernacularTitle>
</Article>
<MedlineJournalInfo><Country>Hungary</Country>
<MedlineTA>Ideggyogy Sz</MedlineTA>
<NlmUniqueID>17510500R</NlmUniqueID>
<ISSNLinking>0019-1442</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D000978">Antiparkinson Agents</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D047908">Intracellular Signaling Peptides and Proteins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D015513">Oncogene Proteins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="C105131">PARK7 protein, human</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D051844">alpha-Synuclein</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 2.7.-</RegistryNumber>
<NameOfSubstance UI="D011494">Protein Kinases</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 2.7.11.1</RegistryNumber>
<NameOfSubstance UI="C495280">LRRK2 protein, human</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 2.7.11.1</RegistryNumber>
<NameOfSubstance UI="C433927">PTEN-induced putative kinase</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 2.7.11.1</RegistryNumber>
<NameOfSubstance UI="D017346">Protein-Serine-Threonine Kinases</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 6.3.2.19</RegistryNumber>
<NameOfSubstance UI="D044767">Ubiquitin-Protein Ligases</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 6.3.2.19</RegistryNumber>
<NameOfSubstance UI="C111567">parkin protein</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D000978">Antiparkinson Agents</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000627">therapeutic use</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D003131">Combined Modality Therapy</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000379">methods</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D003614">Dance Therapy</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="Y" UI="D046690">Deep Brain Stimulation</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D020022">Genetic Predisposition to Disease</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D005820">Genetic Testing</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D015316">Genetic Therapy</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D047908">Intracellular Signaling Peptides and Proteins</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000235">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D009147">Music Therapy</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D015513">Oncogene Proteins</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000235">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D010300">Parkinson Disease</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000175">diagnosis</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000188">drug therapy</QualifierName>
<QualifierName MajorTopicYN="Y" UI="Q000235">genetics</QualifierName>
<QualifierName MajorTopicYN="Y" UI="Q000628">therapy</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D026741">Physical Therapy Modalities</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D011494">Protein Kinases</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000235">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D017346">Protein-Serine-Threonine Kinases</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000235">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D011613">Psychotherapy</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D012064">Relaxation Therapy</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D044767">Ubiquitin-Protein Ligases</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000235">genetics</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D051844">alpha-Synuclein</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000235">genetics</QualifierName>
</MeshHeading>
</MeshHeadingList>
<NumberOfReferences>64</NumberOfReferences>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2009</Year>
<Month>7</Month>
<Day>8</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="pubmed"><Year>2009</Year>
<Month>7</Month>
<Day>8</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>2009</Year>
<Month>7</Month>
<Day>25</Day>
<Hour>9</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">19579663</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Psychologie/explor/DanceTherParkinsonV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000038 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 000038 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Psychologie |area= DanceTherParkinsonV1 |flux= PubMed |étape= Corpus |type= RBID |clé= pubmed:19579663 |texte= [Genetics and present therapy options in Parkinson's disease: a review]. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:19579663" \ | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \ | NlmPubMed2Wicri -a DanceTherParkinsonV1
![]() | This area was generated with Dilib version V0.6.35. | ![]() |