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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Neurologic manifestations of chronic methamphetamine abuse</title><author><name sortKey="Rusyniak, Daniel E" sort="Rusyniak, Daniel E" uniqKey="Rusyniak D" first="Daniel E." last="Rusyniak">Daniel E. Rusyniak</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">21803215</idno><idno type="pmc">3148451</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148451</idno><idno type="RBID">PMC:3148451</idno><idno type="doi">10.1016/j.ncl.2011.05.004</idno><date when="2011">2011</date><idno type="wicri:Area/Pmc/Corpus">000215</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000215</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Neurologic manifestations of chronic methamphetamine abuse</title><author><name sortKey="Rusyniak, Daniel E" sort="Rusyniak, Daniel E" uniqKey="Rusyniak D" first="Daniel E." last="Rusyniak">Daniel E. Rusyniak</name></author></analytic><series><title level="j">Neurologic clinics</title><idno type="ISSN">0733-8619</idno><idno type="eISSN">1557-9875</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><title>Summary</title><p id="P3">Chronic methamphetamine abuse has devastating effects on the central nervous system. The degree to which addicts will tolerate the dysfunction in the way they think, feel, move, and even look, is a powerful testimony to the addictive properties of this drug. While the mechanisms behind these disorders are complex, at their heart they involve the recurring increase in the concentrations of central monoamines with subsequent dysfunction in dopaminergic neurotransmission. The mainstay of treatment for the problems associated with chronic methamphetamine abuse is abstinence. However, by recognizing the manifestations of chronic abuse, clinicians will be better able to help their patients get treatment for their addiction and to deal with the neurologic complications related to chronic abuse.</p></div></front></TEI><pmc article-type="research-article" xml:lang="en"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">8219232</journal-id><journal-id journal-id-type="pubmed-jr-id">5883</journal-id><journal-id journal-id-type="nlm-ta">Neurol Clin</journal-id><journal-title-group><journal-title>Neurologic clinics</journal-title></journal-title-group><issn pub-type="ppub">0733-8619</issn><issn pub-type="epub">1557-9875</issn></journal-meta><article-meta><article-id pub-id-type="pmid">21803215</article-id><article-id pub-id-type="pmc">3148451</article-id><article-id pub-id-type="doi">10.1016/j.ncl.2011.05.004</article-id><article-id pub-id-type="manuscript">NIHMS296743</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Neurologic manifestations of chronic methamphetamine abuse</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Rusyniak</surname><given-names>Daniel E.</given-names></name><degrees>MD</degrees><aff id="A1">Associate Professor of Emergency Medicine, Pharmacology and Toxicology, Adjunct Associate Clinical Professor of Neurology, Department of Emergency Medicine, Indiana University School of Medicine, 1050 Wishard Blvd, Rm 2200, Indianapolis, IN46202, 317 630–7276, 317 656–4216 (fax)</aff><email>drusynia@iupui.edu</email></contrib></contrib-group><pub-date pub-type="nihms-submitted"><day>17</day><month>5</month><year>2011</year></pub-date><pub-date pub-type="epub"><day>24</day><month>6</month><year>2011</year></pub-date><pub-date pub-type="ppub"><month>8</month><year>2011</year></pub-date><pub-date pub-type="pmc-release"><day>1</day><month>8</month><year>2012</year></pub-date><volume>29</volume><issue>3</issue><fpage>641</fpage><lpage>655</lpage><permissions><copyright-statement>© 2011 Elsevier Inc. All rights reserved.</copyright-statement><copyright-year>2011</copyright-year></permissions><abstract><title>Summary</title><p id="P3">Chronic methamphetamine abuse has devastating effects on the central nervous system. The degree to which addicts will tolerate the dysfunction in the way they think, feel, move, and even look, is a powerful testimony to the addictive properties of this drug. While the mechanisms behind these disorders are complex, at their heart they involve the recurring increase in the concentrations of central monoamines with subsequent dysfunction in dopaminergic neurotransmission. The mainstay of treatment for the problems associated with chronic methamphetamine abuse is abstinence. However, by recognizing the manifestations of chronic abuse, clinicians will be better able to help their patients get treatment for their addiction and to deal with the neurologic complications related to chronic abuse.</p></abstract><kwd-group><kwd>Methamphetamine abuse</kwd><kwd>Psychosis</kwd><kwd>Parkinson’s</kwd><kwd>Choreoathetoid</kwd><kwd>Punding</kwd><kwd>Formication</kwd></kwd-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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