Superantibody activities: new players in innate and adaptive immune responses
Identifieur interne : 001169 ( Main/Curation ); précédent : 001168; suivant : 001170Superantibody activities: new players in innate and adaptive immune responses
Auteurs : Heinz Kohler [États-Unis] ; Sudhir Paul [États-Unis]Source :
- Immunology Today [ 0167-5699 ] ; 1998.
Abstract
Heinz Kohler and Sudhir Paul propose the term superantibody to describe multifunctional antibodies that combine the classical antigen-binding function with a nonclassical, qualitatively distinct, biological function. Discrete ligand-binding sites in the variable domain within these antibodies are responsible for their nonclassical biological functions, such as chemical catalysis, nucleotide binding, self-binding and superantigen binding.
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DOI: 10.1016/S0167-5699(97)01234-6
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