Residential proximity to agricultural pesticide use and incidence of breast cancer in the California Teachers Study cohort.
Identifieur interne : 000426 ( PubMed/Corpus ); précédent : 000425; suivant : 000427Residential proximity to agricultural pesticide use and incidence of breast cancer in the California Teachers Study cohort.
Auteurs : Peggy Reynolds ; Susan E. Hurley ; Debbie E. Goldberg ; Sauda Yerabati ; Robert B. Gunier ; Andrew Hertz ; Hoda Anton-Culver ; Leslie Bernstein ; Dennis Deapen ; Pamela L. Horn-Ross ; David Peel ; Richard Pinder ; R K Ronald K. Ross ; Dee West ; William E. Wright ; Argyrios ZiogasSource :
- Environmental research [ 0013-9351 ] ; 2004.
English descriptors
- KwdEn :
- Adult, Aged, Aged, 80 and over, Agrochemicals (poisoning), Breast Neoplasms (chemically induced), Breast Neoplasms (epidemiology), California (epidemiology), Cohort Studies, Environmental Exposure (adverse effects), Faculty, Female, Geographic Information Systems, Housing, Humans, Incidence, Middle Aged, Pesticides (poisoning), Proportional Hazards Models.
- MESH :
- chemical , poisoning : Agrochemicals, Pesticides.
- geographic , epidemiology : California.
- adverse effects : Environmental Exposure.
- chemically induced : Breast Neoplasms.
- epidemiology : Breast Neoplasms.
- Adult, Aged, Aged, 80 and over, Cohort Studies, Faculty, Female, Geographic Information Systems, Housing, Humans, Incidence, Middle Aged, Proportional Hazards Models.
Abstract
We examined the association between residential proximity to agricultural pesticide use and breast cancer incidence among members of the California Teachers Study cohort, a large study of professional school employees with extensive information on breast cancer risk factors, followed for cancer incidence since 1995. We identified 1552 invasive breast cancer cases, diagnosed between 1996 and 1999, among 114,835 cohort members. We used California Pesticide Use Reporting data to select pesticides for analysis based on use volume, carcinogenic potential, and exposure potential; a Geographic Information System was used to estimate pesticide applications within a half-mile radius of subjects' residences. We applied Cox proportional hazard models to estimate hazard rate ratios (HR) for selected pesticides, adjusting for age, race, and socioeconomic status. We saw no association between residential proximity to recent agricultural pesticide use and invasive breast cancer incidence. HR estimates for the highest compared to the lowest exposure categories for groups of agents were as follows: probable or likely carcinogens (1.07, 95% confidence interval (CI): 0.86-1.32), possible or suggestive carcinogens (1.06, 95% CI: 0.87-1.29), mammary carcinogens (1.15, 95% CI: 0.90-1.48), and endocrine disruptors (1.03, 95% CI: 0.86-1.25). HR estimates for other groups and individual pesticides did not differ from unity, nor was there a trend for any groupings of or individual pesticides examined. Stratifying by menopausal status or family history of breast cancer did not substantially affect our results. Our analyses suggest that breast cancer incidence is not elevated in areas of recent, high agricultural pesticide use in California.
DOI: 10.1016/j.envres.2004.03.001
PubMed: 15325881
Links to Exploration step
pubmed:15325881Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Residential proximity to agricultural pesticide use and incidence of breast cancer in the California Teachers Study cohort.</title><author><name sortKey="Reynolds, Peggy" sort="Reynolds, Peggy" uniqKey="Reynolds P" first="Peggy" last="Reynolds">Peggy Reynolds</name><affiliation><nlm:affiliation>Environmental Health Investigations Branch, California Department of Health Services, 1515 Clay Street, Suite 1700, Oakland, CA 94612, USA. preynold@dhs.ca.gov</nlm:affiliation></affiliation></author><author><name sortKey="Hurley, Susan E" sort="Hurley, Susan E" uniqKey="Hurley S" first="Susan E" last="Hurley">Susan E. Hurley</name></author><author><name sortKey="Goldberg, Debbie E" sort="Goldberg, Debbie E" uniqKey="Goldberg D" first="Debbie E" last="Goldberg">Debbie E. Goldberg</name></author><author><name sortKey="Yerabati, Sauda" sort="Yerabati, Sauda" uniqKey="Yerabati S" first="Sauda" last="Yerabati">Sauda Yerabati</name></author><author><name sortKey="Gunier, Robert B" sort="Gunier, Robert B" uniqKey="Gunier R" first="Robert B" last="Gunier">Robert B. Gunier</name></author><author><name sortKey="Hertz, Andrew" sort="Hertz, Andrew" uniqKey="Hertz A" first="Andrew" last="Hertz">Andrew Hertz</name></author><author><name sortKey="Anton Culver, Hoda" sort="Anton Culver, Hoda" uniqKey="Anton Culver H" first="Hoda" last="Anton-Culver">Hoda Anton-Culver</name></author><author><name sortKey="Bernstein, Leslie" sort="Bernstein, Leslie" uniqKey="Bernstein L" first="Leslie" last="Bernstein">Leslie Bernstein</name></author><author><name sortKey="Deapen, Dennis" sort="Deapen, Dennis" uniqKey="Deapen D" first="Dennis" last="Deapen">Dennis Deapen</name></author><author><name sortKey="Horn Ross, Pamela L" sort="Horn Ross, Pamela L" uniqKey="Horn Ross P" first="Pamela L" last="Horn-Ross">Pamela L. Horn-Ross</name></author><author><name sortKey="Peel, David" sort="Peel, David" uniqKey="Peel D" first="David" last="Peel">David Peel</name></author><author><name sortKey="Pinder, Richard" sort="Pinder, Richard" uniqKey="Pinder R" first="Richard" last="Pinder">Richard Pinder</name></author><author><name sortKey="Ross, R K Ronald K" sort="Ross, R K Ronald K" uniqKey="Ross R" first="R K Ronald K" last="Ross">R K Ronald K. Ross</name></author><author><name sortKey="West, Dee" sort="West, Dee" uniqKey="West D" first="Dee" last="West">Dee West</name></author><author><name sortKey="Wright, William E" sort="Wright, William E" uniqKey="Wright W" first="William E" last="Wright">William E. Wright</name></author><author><name sortKey="Ziogas, Argyrios" sort="Ziogas, Argyrios" uniqKey="Ziogas A" first="Argyrios" last="Ziogas">Argyrios Ziogas</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2004">2004</date><idno type="RBID">pubmed:15325881</idno><idno type="pmid">15325881</idno><idno type="doi">10.1016/j.envres.2004.03.001</idno><idno type="wicri:Area/PubMed/Corpus">000426</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000426</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Residential proximity to agricultural pesticide use and incidence of breast cancer in the California Teachers Study cohort.</title><author><name sortKey="Reynolds, Peggy" sort="Reynolds, Peggy" uniqKey="Reynolds P" first="Peggy" last="Reynolds">Peggy Reynolds</name><affiliation><nlm:affiliation>Environmental Health Investigations Branch, California Department of Health Services, 1515 Clay Street, Suite 1700, Oakland, CA 94612, USA. preynold@dhs.ca.gov</nlm:affiliation></affiliation></author><author><name sortKey="Hurley, Susan E" sort="Hurley, Susan E" uniqKey="Hurley S" first="Susan E" last="Hurley">Susan E. Hurley</name></author><author><name sortKey="Goldberg, Debbie E" sort="Goldberg, Debbie E" uniqKey="Goldberg D" first="Debbie E" last="Goldberg">Debbie E. Goldberg</name></author><author><name sortKey="Yerabati, Sauda" sort="Yerabati, Sauda" uniqKey="Yerabati S" first="Sauda" last="Yerabati">Sauda Yerabati</name></author><author><name sortKey="Gunier, Robert B" sort="Gunier, Robert B" uniqKey="Gunier R" first="Robert B" last="Gunier">Robert B. Gunier</name></author><author><name sortKey="Hertz, Andrew" sort="Hertz, Andrew" uniqKey="Hertz A" first="Andrew" last="Hertz">Andrew Hertz</name></author><author><name sortKey="Anton Culver, Hoda" sort="Anton Culver, Hoda" uniqKey="Anton Culver H" first="Hoda" last="Anton-Culver">Hoda Anton-Culver</name></author><author><name sortKey="Bernstein, Leslie" sort="Bernstein, Leslie" uniqKey="Bernstein L" first="Leslie" last="Bernstein">Leslie Bernstein</name></author><author><name sortKey="Deapen, Dennis" sort="Deapen, Dennis" uniqKey="Deapen D" first="Dennis" last="Deapen">Dennis Deapen</name></author><author><name sortKey="Horn Ross, Pamela L" sort="Horn Ross, Pamela L" uniqKey="Horn Ross P" first="Pamela L" last="Horn-Ross">Pamela L. Horn-Ross</name></author><author><name sortKey="Peel, David" sort="Peel, David" uniqKey="Peel D" first="David" last="Peel">David Peel</name></author><author><name sortKey="Pinder, Richard" sort="Pinder, Richard" uniqKey="Pinder R" first="Richard" last="Pinder">Richard Pinder</name></author><author><name sortKey="Ross, R K Ronald K" sort="Ross, R K Ronald K" uniqKey="Ross R" first="R K Ronald K" last="Ross">R K Ronald K. Ross</name></author><author><name sortKey="West, Dee" sort="West, Dee" uniqKey="West D" first="Dee" last="West">Dee West</name></author><author><name sortKey="Wright, William E" sort="Wright, William E" uniqKey="Wright W" first="William E" last="Wright">William E. Wright</name></author><author><name sortKey="Ziogas, Argyrios" sort="Ziogas, Argyrios" uniqKey="Ziogas A" first="Argyrios" last="Ziogas">Argyrios Ziogas</name></author></analytic><series><title level="j">Environmental research</title><idno type="ISSN">0013-9351</idno><imprint><date when="2004" type="published">2004</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Agrochemicals (poisoning)</term><term>Breast Neoplasms (chemically induced)</term><term>Breast Neoplasms (epidemiology)</term><term>California (epidemiology)</term><term>Cohort Studies</term><term>Environmental Exposure (adverse effects)</term><term>Faculty</term><term>Female</term><term>Geographic Information Systems</term><term>Housing</term><term>Humans</term><term>Incidence</term><term>Middle Aged</term><term>Pesticides (poisoning)</term><term>Proportional Hazards Models</term></keywords><keywords scheme="MESH" type="chemical" qualifier="poisoning" xml:lang="en"><term>Agrochemicals</term><term>Pesticides</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>California</term></keywords><keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Environmental Exposure</term></keywords><keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Breast Neoplasms</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Breast Neoplasms</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Aged, 80 and over</term><term>Cohort Studies</term><term>Faculty</term><term>Female</term><term>Geographic Information Systems</term><term>Housing</term><term>Humans</term><term>Incidence</term><term>Middle Aged</term><term>Proportional Hazards Models</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">We examined the association between residential proximity to agricultural pesticide use and breast cancer incidence among members of the California Teachers Study cohort, a large study of professional school employees with extensive information on breast cancer risk factors, followed for cancer incidence since 1995. We identified 1552 invasive breast cancer cases, diagnosed between 1996 and 1999, among 114,835 cohort members. We used California Pesticide Use Reporting data to select pesticides for analysis based on use volume, carcinogenic potential, and exposure potential; a Geographic Information System was used to estimate pesticide applications within a half-mile radius of subjects' residences. We applied Cox proportional hazard models to estimate hazard rate ratios (HR) for selected pesticides, adjusting for age, race, and socioeconomic status. We saw no association between residential proximity to recent agricultural pesticide use and invasive breast cancer incidence. HR estimates for the highest compared to the lowest exposure categories for groups of agents were as follows: probable or likely carcinogens (1.07, 95% confidence interval (CI): 0.86-1.32), possible or suggestive carcinogens (1.06, 95% CI: 0.87-1.29), mammary carcinogens (1.15, 95% CI: 0.90-1.48), and endocrine disruptors (1.03, 95% CI: 0.86-1.25). HR estimates for other groups and individual pesticides did not differ from unity, nor was there a trend for any groupings of or individual pesticides examined. Stratifying by menopausal status or family history of breast cancer did not substantially affect our results. Our analyses suggest that breast cancer incidence is not elevated in areas of recent, high agricultural pesticide use in California.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">15325881</PMID><DateCreated><Year>2004</Year><Month>08</Month><Day>24</Day></DateCreated><DateCompleted><Year>2004</Year><Month>10</Month><Day>07</Day></DateCompleted><DateRevised><Year>2007</Year><Month>11</Month><Day>14</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0013-9351</ISSN><JournalIssue CitedMedium="Print"><Volume>96</Volume><Issue>2</Issue><PubDate><Year>2004</Year><Month>Oct</Month></PubDate></JournalIssue><Title>Environmental research</Title><ISOAbbreviation>Environ. Res.</ISOAbbreviation></Journal><ArticleTitle>Residential proximity to agricultural pesticide use and incidence of breast cancer in the California Teachers Study cohort.</ArticleTitle><Pagination><MedlinePgn>206-18</MedlinePgn></Pagination><Abstract><AbstractText>We examined the association between residential proximity to agricultural pesticide use and breast cancer incidence among members of the California Teachers Study cohort, a large study of professional school employees with extensive information on breast cancer risk factors, followed for cancer incidence since 1995. We identified 1552 invasive breast cancer cases, diagnosed between 1996 and 1999, among 114,835 cohort members. We used California Pesticide Use Reporting data to select pesticides for analysis based on use volume, carcinogenic potential, and exposure potential; a Geographic Information System was used to estimate pesticide applications within a half-mile radius of subjects' residences. We applied Cox proportional hazard models to estimate hazard rate ratios (HR) for selected pesticides, adjusting for age, race, and socioeconomic status. We saw no association between residential proximity to recent agricultural pesticide use and invasive breast cancer incidence. HR estimates for the highest compared to the lowest exposure categories for groups of agents were as follows: probable or likely carcinogens (1.07, 95% confidence interval (CI): 0.86-1.32), possible or suggestive carcinogens (1.06, 95% CI: 0.87-1.29), mammary carcinogens (1.15, 95% CI: 0.90-1.48), and endocrine disruptors (1.03, 95% CI: 0.86-1.25). HR estimates for other groups and individual pesticides did not differ from unity, nor was there a trend for any groupings of or individual pesticides examined. Stratifying by menopausal status or family history of breast cancer did not substantially affect our results. Our analyses suggest that breast cancer incidence is not elevated in areas of recent, high agricultural pesticide use in California.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Reynolds</LastName><ForeName>Peggy</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Environmental Health Investigations Branch, California Department of Health Services, 1515 Clay Street, Suite 1700, Oakland, CA 94612, USA. preynold@dhs.ca.gov</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Hurley</LastName><ForeName>Susan E</ForeName><Initials>SE</Initials></Author><Author ValidYN="Y"><LastName>Goldberg</LastName><ForeName>Debbie E</ForeName><Initials>DE</Initials></Author><Author ValidYN="Y"><LastName>Yerabati</LastName><ForeName>Sauda</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Gunier</LastName><ForeName>Robert B</ForeName><Initials>RB</Initials></Author><Author ValidYN="Y"><LastName>Hertz</LastName><ForeName>Andrew</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><LastName>Anton-Culver</LastName><ForeName>Hoda</ForeName><Initials>H</Initials></Author><Author ValidYN="Y"><LastName>Bernstein</LastName><ForeName>Leslie</ForeName><Initials>L</Initials></Author><Author ValidYN="Y"><LastName>Deapen</LastName><ForeName>Dennis</ForeName><Initials>D</Initials></Author><Author ValidYN="Y"><LastName>Horn-Ross</LastName><ForeName>Pamela L</ForeName><Initials>PL</Initials></Author><Author ValidYN="Y"><LastName>Peel</LastName><ForeName>David</ForeName><Initials>D</Initials></Author><Author ValidYN="Y"><LastName>Pinder</LastName><ForeName>Richard</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Ross</LastName><ForeName>R K Ronald K</ForeName><Initials>RK</Initials></Author><Author ValidYN="Y"><LastName>West</LastName><ForeName>Dee</ForeName><Initials>D</Initials></Author><Author ValidYN="Y"><LastName>Wright</LastName><ForeName>William E</ForeName><Initials>WE</Initials></Author><Author ValidYN="Y"><LastName>Ziogas</LastName><ForeName>Argyrios</ForeName><Initials>A</Initials></Author><Author ValidYN="Y"><CollectiveName>California Teachers Study</CollectiveName></Author></AuthorList><Language>eng</Language><GrantList CompleteYN="Y"><Grant><GrantID>R01 CA77398</GrantID><Acronym>CA</Acronym><Agency>NCI NIH HHS</Agency><Country>United States</Country></Grant></GrantList><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType><PublicationType UI="D013487">Research Support, U.S. Gov't, P.H.S.</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>Netherlands</Country><MedlineTA>Environ Res</MedlineTA><NlmUniqueID>0147621</NlmUniqueID><ISSNLinking>0013-9351</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D016573">Agrochemicals</NameOfSubstance></Chemical><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D010575">Pesticides</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000369" MajorTopicYN="N">Aged, 80 and over</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016573" MajorTopicYN="N">Agrochemicals</DescriptorName><QualifierName UI="Q000506" MajorTopicYN="Y">poisoning</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001943" MajorTopicYN="N">Breast Neoplasms</DescriptorName><QualifierName UI="Q000139" MajorTopicYN="Y">chemically induced</QualifierName><QualifierName UI="Q000453" MajorTopicYN="Y">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002140" MajorTopicYN="N" Type="Geographic">California</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015331" MajorTopicYN="N">Cohort Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D004781" MajorTopicYN="N">Environmental Exposure</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="Y">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005178" MajorTopicYN="N">Faculty</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D040362" MajorTopicYN="N">Geographic Information Systems</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006798" MajorTopicYN="N">Housing</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015994" MajorTopicYN="N">Incidence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010575" MajorTopicYN="N">Pesticides</DescriptorName><QualifierName UI="Q000506" MajorTopicYN="Y">poisoning</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D016016" MajorTopicYN="N">Proportional Hazards Models</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2003</Year><Month>07</Month><Day>11</Day></PubMedPubDate><PubMedPubDate PubStatus="revised"><Year>2004</Year><Month>01</Month><Day>21</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2004</Year><Month>03</Month><Day>02</Day></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2004</Year><Month>8</Month><Day>25</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2004</Year><Month>10</Month><Day>8</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2004</Year><Month>8</Month><Day>25</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">15325881</ArticleId><ArticleId IdType="doi">10.1016/j.envres.2004.03.001</ArticleId><ArticleId IdType="pii">S0013935104000520</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Agronomie/explor/SisAgriV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000426 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 000426 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Agronomie
|area= SisAgriV1
|flux= PubMed
|étape= Corpus
|type= RBID
|clé= pubmed:15325881
|texte= Residential proximity to agricultural pesticide use and incidence of breast cancer in the California Teachers Study cohort.
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:15325881" \
| HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \
| NlmPubMed2Wicri -a SisAgriV1
| This area was generated with Dilib version V0.6.28. |  |