Transcriptional regulation of the proC gene of Salmonella typhimurium.
Identifieur interne : 000142 ( Ncbi/Merge ); précédent : 000141; suivant : 000143Transcriptional regulation of the proC gene of Salmonella typhimurium.
Auteurs : R A Brady ; L N CsonkaSource :
- Journal of Bacteriology [ 0021-9193 ] ; 1988.
Abstract
We found that the expression of beta-galactosidase in Salmonella typhimurium strains carrying proC-lacZ fusions was neither repressed by excess proline nor derepressed by proline limitation. Except for a three- to fourfold decrease in the beta-galactosidase specific activity under conditions causing a severely reduced growth rate, the expression of the proC-lacZ fusions was nearly invariant under a variety of culture conditions. Thus, the proC gene is unlike most other amino acid biosynthetic genes in that its expression is nearly constitutive.
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PubMed: 3129409
PubMed Central: 211133
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<front><journal-meta><journal-id journal-id-type="nlm-ta">J Bacteriol</journal-id><journal-title>Journal of Bacteriology</journal-title><issn pub-type="ppub">0021-9193</issn><issn pub-type="epub">1098-5530</issn></journal-meta><article-meta><article-id pub-id-type="pmid">3129409</article-id><article-id pub-id-type="pmc">211133</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title>Transcriptional regulation of the proC gene of Salmonella typhimurium.</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Brady</surname><given-names>R A</given-names></name></contrib><contrib contrib-type="author"><name><surname>Csonka</surname><given-names>L N</given-names></name></contrib></contrib-group><aff>Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907.</aff><pub-date pub-type="ppub"><month>5</month><year>1988</year></pub-date><volume>170</volume><issue>5</issue><fpage>2379</fpage><lpage>2382</lpage><abstract><p>We found that the expression of beta-galactosidase in Salmonella typhimurium strains carrying proC-lacZ fusions was neither repressed by excess proline nor derepressed by proline limitation. Except for a three- to fourfold decrease in the beta-galactosidase specific activity under conditions causing a severely reduced growth rate, the expression of the proC-lacZ fusions was nearly invariant under a variety of culture conditions. Thus, the proC gene is unlike most other amino acid biosynthetic genes in that its expression is nearly constitutive.</p></abstract></article-meta></front></pmc><affiliations><list></list><tree><noCountry><name sortKey="Brady, R A" sort="Brady, R A" uniqKey="Brady R" first="R A" last="Brady">R A Brady</name><name sortKey="Csonka, L N" sort="Csonka, L N" uniqKey="Csonka L" first="L N" last="Csonka">L N Csonka</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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