The preparation of highly concentrated allergenic extracts by increasing the concentration of extraction
Identifieur interne : 003C93 ( Istex/Corpus ); précédent : 003C92; suivant : 003C94The preparation of highly concentrated allergenic extracts by increasing the concentration of extraction
Auteurs : Stanley F. Hampton ; Mary C. Johnson ; Sam Frankel ; Allne W. SchieleSource :
- Journal of Allergy [ 0021-8707 ] ; 1954.
Abstract
1. 1. Highly concentrated timothy and low ragweed pollen extracts have been prepared by direct extraction. 2. 2. Extracts of timothy and low ragweed pollens, prepared in increasing weight by volume ratios, from 5 to 50 per cent, showed a distinct proportionality, indicating extraction in linear ratios, as measured by total and phosphotungstic acid-precipitable nitrogen content, concentration of reducing substances, and reagin neutralization activity. 3. 3. The use of glycerinated extracting fluids was necessary in the preparation of such highly concentrated and potent extracts to avoid sedimentation and to preserve activity.
Url:
DOI: 10.1016/0021-8707(55)90104-0
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<front><div type="abstract" xml:lang="en">1. 1. Highly concentrated timothy and low ragweed pollen extracts have been prepared by direct extraction. 2. 2. Extracts of timothy and low ragweed pollens, prepared in increasing weight by volume ratios, from 5 to 50 per cent, showed a distinct proportionality, indicating extraction in linear ratios, as measured by total and phosphotungstic acid-precipitable nitrogen content, concentration of reducing substances, and reagin neutralization activity. 3. 3. The use of glycerinated extracting fluids was necessary in the preparation of such highly concentrated and potent extracts to avoid sedimentation and to preserve activity.</div>
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<abstract lang="en">1. 1. Highly concentrated timothy and low ragweed pollen extracts have been prepared by direct extraction. 2. 2. Extracts of timothy and low ragweed pollens, prepared in increasing weight by volume ratios, from 5 to 50 per cent, showed a distinct proportionality, indicating extraction in linear ratios, as measured by total and phosphotungstic acid-precipitable nitrogen content, concentration of reducing substances, and reagin neutralization activity. 3. 3. The use of glycerinated extracting fluids was necessary in the preparation of such highly concentrated and potent extracts to avoid sedimentation and to preserve activity.</abstract>
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