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Radiocarbon cholesterol turnover in cholesterol pericarditis

Identifieur interne : 003897 ( Istex/Corpus ); précédent : 003896; suivant : 003898

Radiocarbon cholesterol turnover in cholesterol pericarditis

Auteurs : J. E. Doherty ; B. J. Jenkins ; Jacquelyn Gammill ; Joyce Sherwoo ; W. H. Van Wagoner

Source :

RBID : ISTEX:FFA9663AA830A22EC85AD5A3002882636E898BAC

Abstract

A patient with chronic effusive pericarditis of undetermined etiology, associated with cholesterol crystals in the effusion, is described. A radiocarbon cholesterol turnover study revealed a dominant half-time in the pericardial effusion of sixty days, compared to a fifty day half-time in the serum. The equilibration time of the specific radioactivity of cholesterol in the pericardial fluid with the serum was thirty-three days. A fourteen day difference was noted in achieving a plateau between the serum and pericardial fluid. These findings suggest an abnormality in cholesterol transport. Partial pericardectomy resulted in apparent cure in this case.

Url:
DOI: 10.1016/0002-9343(66)90027-1

Links to Exploration step

ISTEX:FFA9663AA830A22EC85AD5A3002882636E898BAC

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