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Lipid Relationships in Dialysis and Rental Transplant Patients

Identifieur interne : 003440 ( Istex/Corpus ); précédent : 003439; suivant : 003441

Lipid Relationships in Dialysis and Rental Transplant Patients

Auteurs : A. J. Nicholls ; A. M. Cumming ; G. R. D. Catto ; N. Edward ; J. Engeset

Source :

RBID : ISTEX:89D88169E9475DF04AE5ABF6BE2B1C3164703345

Abstract

The relationship of high density Iipoprotein cholesterol (HDL-CHOL) to other lipid fractions and the factors influencing post-transplant hyperlipldaemia have been explored in 28 chronic haemodialysls patients and 20 stable renal allograft recipients. In both groups of patients mean triglyceride (TG) and very low density Iipoprotein cholesterol (VLDL-CHOL) were elevated, but total CHOL and low density Iipoprotein cholesterol (LDL-CHOL) were elevated only in transplanted patients. HDL-CHOL was uniformly low in dialysis patients irrespective of TG, whereas after transplantation mean HDL-CHOL was normal and varied inversely with TG and VLDL-CHOL. Serum creatinine correlated with TG and VLDL-CHOL in transplant patients, and was inversely related to HDL-CHOL. No factors correlated with CHOL or LDL-CHOL in transplant patients, but these lipids were only moderately elevated. Hyperllpldaemla in dialysis and transplant patients is not Invariable; its importance for atherogenesis remains to be determined.

Url:
DOI: 10.1093/oxfordjournals.qjmed.a067677

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ISTEX:89D88169E9475DF04AE5ABF6BE2B1C3164703345

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