Expanding repertoire in the oculomotor periphery: selective compartmental function in rectus extraocular muscles
Identifieur interne : 000556 ( Istex/Corpus ); précédent : 000555; suivant : 000557Expanding repertoire in the oculomotor periphery: selective compartmental function in rectus extraocular muscles
Auteurs : Joseph L. Demer ; Robert A. Clark ; Roberta M. Da Silva Costa ; Jennifer Kung ; Lawrence YooSource :
- Annals of the New York Academy of Sciences [ 0077-8923 ] ; 2011-09.
English descriptors
- KwdEn :
Abstract
Since connective tissue pulleys implement Listing's law by systematically changing rectus extraocular muscle (EOM) pulling directions, non‐Listing's law gaze dependence of the vestibulo‐ocular reflex is currently inexplicable. Differential activation of compartments within rectus EOMs may endow the ocular motor system with more behavioral diversity than previously supposed. Innervation to horizontal, but not vertical, rectus EOMs of mammals is segregated into superior and inferior compartments. Magnetic resonance imaging in normal subjects demonstrates contractile changes in the lateral rectus (LR) inferior, but not superior, compartment during ocular counter‐rolling (OCR) induced by head tilt. In human orbits ipsilesional to unilateral superior oblique palsy, neither LR compartment exhibits contractile change during head tilt, although the inferior compartment contracts normally in contralesional orbits. This suggests that differential compartmental LR contraction assists normal OCR. Computational simulation suggests that differential compartmental action in horizontal rectus EOMs could achieve more force than required by vertical fusional vergence.
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DOI: 10.1111/j.1749-6632.2011.06112.x
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<name type="personal"><namePart type="given">Lawrence</namePart>
<namePart type="family">Yoo</namePart>
<affiliation>Department of Ophthalmology</affiliation>
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<typeOfResource>text</typeOfResource>
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<originInfo><publisher>Blackwell Publishing Inc</publisher>
<place><placeTerm type="text">Malden, USA</placeTerm>
</place>
<dateIssued encoding="w3cdtf">2011-09</dateIssued>
<copyrightDate encoding="w3cdtf">2011</copyrightDate>
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<language><languageTerm type="code" authority="rfc3066">en</languageTerm>
<languageTerm type="code" authority="iso639-2b">eng</languageTerm>
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<extent unit="references">57</extent>
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<abstract lang="en">Since connective tissue pulleys implement Listing's law by systematically changing rectus extraocular muscle (EOM) pulling directions, non‐Listing's law gaze dependence of the vestibulo‐ocular reflex is currently inexplicable. Differential activation of compartments within rectus EOMs may endow the ocular motor system with more behavioral diversity than previously supposed. Innervation to horizontal, but not vertical, rectus EOMs of mammals is segregated into superior and inferior compartments. Magnetic resonance imaging in normal subjects demonstrates contractile changes in the lateral rectus (LR) inferior, but not superior, compartment during ocular counter‐rolling (OCR) induced by head tilt. In human orbits ipsilesional to unilateral superior oblique palsy, neither LR compartment exhibits contractile change during head tilt, although the inferior compartment contracts normally in contralesional orbits. This suggests that differential compartmental LR contraction assists normal OCR. Computational simulation suggests that differential compartmental action in horizontal rectus EOMs could achieve more force than required by vertical fusional vergence.</abstract>
<subject lang="en"><genre>keywords</genre>
<topic>extraocular muscles</topic>
<topic>magnetic resonance imaging</topic>
<topic>motor nerve</topic>
<topic>pulleys</topic>
<topic>vestibulo‐ocular reflex</topic>
</subject>
<relatedItem type="host"><titleInfo><title>Annals of the New York Academy of Sciences</title>
</titleInfo>
<genre type="journal">journal</genre>
<identifier type="ISSN">0077-8923</identifier>
<identifier type="eISSN">1749-6632</identifier>
<identifier type="DOI">10.1111/(ISSN)1749-6632</identifier>
<identifier type="PublisherID">NYAS</identifier>
<part><date>2011</date>
<detail type="title"><title>Basic and Clinical Ocular Motor and Vestibular Research</title>
</detail>
<detail type="volume"><caption>vol.</caption>
<number>1233</number>
</detail>
<detail type="issue"><caption>no.</caption>
<number>1</number>
</detail>
<extent unit="pages"><start>8</start>
<end>16</end>
<total>9</total>
</extent>
</part>
</relatedItem>
<identifier type="istex">71F1B0559BB6BE959470DE1928664DB8B1023121</identifier>
<identifier type="DOI">10.1111/j.1749-6632.2011.06112.x</identifier>
<identifier type="ArticleID">NYAS6112</identifier>
<accessCondition type="use and reproduction" contentType="copyright">© 2011 New York Academy of Sciences</accessCondition>
<recordInfo><recordContentSource>WILEY</recordContentSource>
<recordOrigin>Blackwell Publishing Inc</recordOrigin>
</recordInfo>
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<serie></serie>
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