Cerebrospinal fluid reconstitution via a perfusion-based cadaveric model: feasibility study demonstrating surgical simulation of neuroendoscopic procedures.
Identifieur interne : 000422 ( PubMed/Checkpoint ); précédent : 000421; suivant : 000423Cerebrospinal fluid reconstitution via a perfusion-based cadaveric model: feasibility study demonstrating surgical simulation of neuroendoscopic procedures.
Auteurs : Jesse L. Winer ; Daniel R. Kramer ; Richard A. Robison ; Ifije Ohiorhenuan ; Michael Minneti [États-Unis] ; Steven Giannotta ; Gabriel ZadaSource :
- Journal of neurosurgery [ 1933-0693 ] ; 2015.
English descriptors
- KwdEn :
- Cadaver, Cerebral Ventricles (anatomy & histology), Cerebral Ventricles (surgery), Cerebrospinal Fluid (chemistry), Clinical Competence, Dura Mater (anatomy & histology), Dura Mater (surgery), Feasibility Studies, Humans, Hypothalamus (anatomy & histology), Hypothalamus (surgery), Laminectomy, Learning Curve, Neuroendoscopy (education), Neuroendoscopy (methods), Neuronavigation (education), Neuronavigation (methods), Neurosurgical Procedures (education), Neurosurgical Procedures (methods), Septum Pellucidum (anatomy & histology), Septum Pellucidum (surgery), Ventriculostomy (methods).
- MESH :
- anatomy & histology : Cerebral Ventricles, Dura Mater, Hypothalamus, Septum Pellucidum.
- chemistry : Cerebrospinal Fluid.
- education : Neuroendoscopy, Neuronavigation, Neurosurgical Procedures.
- methods : Neuroendoscopy, Neuronavigation, Neurosurgical Procedures, Ventriculostomy.
- surgery : Cerebral Ventricles, Dura Mater, Hypothalamus, Septum Pellucidum.
- Cadaver, Clinical Competence, Feasibility Studies, Humans, Laminectomy, Learning Curve.
Abstract
Cadaveric surgical simulation carries the advantage of realistic anatomy and haptic feedback but has been historically difficult to model for intraventricular approaches given the need for active flow of CSF. This feasibility study was designed to simulate intraventricular neuroendoscopic approaches and techniques by reconstituting natural CSF flow in a cadaveric model. In 10 fresh human cadavers, a simple cervical laminectomy and dural opening were made, and a 12-gauge arterial catheter was introduced. Saline was continuously perfused at physiological CSF pressures to reconstitute the subarachnoid space and ventricles. A neuroendoscope was subsequently inserted via a standard right frontal bur hole. In 8 of the 10 cadavers, adequate reconstitution and endoscopic access of the lateral and third ventricles were achieved. In 2 cadavers, ventricular access was not feasible, perhaps because of a small ventricle size and/or deteriorated tissue quality. In all 8 cadavers with successful CSF flow reconstitution and endoscopic access, identifying the foramen of Monro was possible, as was performing septum pellucidotomy and endoscopic third ventriculostomy. Furthermore, navigation of the cerebral aqueduct, fourth ventricle, prepontine cistern, and suprasellar cistern via the lamina terminalis was possible, providing a complementary educational paradigm for resident education that cannot typically be performed in live surgery. Surgical simulation plays a critical and increasingly prominent role in surgical education, particularly for techniques with steep learning curves including intraventricular neuroendoscopic procedures. This novel model provides feasible and realistic surgical simulation of neuroendoscopic intraventricular procedures and approaches.
DOI: 10.3171/2014.10.JNS1497
PubMed: 25859805
Affiliations:
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<term>Cerebral Ventricles (anatomy & histology)</term>
<term>Cerebral Ventricles (surgery)</term>
<term>Cerebrospinal Fluid (chemistry)</term>
<term>Clinical Competence</term>
<term>Dura Mater (anatomy & histology)</term>
<term>Dura Mater (surgery)</term>
<term>Feasibility Studies</term>
<term>Humans</term>
<term>Hypothalamus (anatomy & histology)</term>
<term>Hypothalamus (surgery)</term>
<term>Laminectomy</term>
<term>Learning Curve</term>
<term>Neuroendoscopy (education)</term>
<term>Neuroendoscopy (methods)</term>
<term>Neuronavigation (education)</term>
<term>Neuronavigation (methods)</term>
<term>Neurosurgical Procedures (education)</term>
<term>Neurosurgical Procedures (methods)</term>
<term>Septum Pellucidum (anatomy & histology)</term>
<term>Septum Pellucidum (surgery)</term>
<term>Ventriculostomy (methods)</term>
</keywords>
<keywords scheme="MESH" qualifier="anatomy & histology" xml:lang="en"><term>Cerebral Ventricles</term>
<term>Dura Mater</term>
<term>Hypothalamus</term>
<term>Septum Pellucidum</term>
</keywords>
<keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Cerebrospinal Fluid</term>
</keywords>
<keywords scheme="MESH" qualifier="education" xml:lang="en"><term>Neuroendoscopy</term>
<term>Neuronavigation</term>
<term>Neurosurgical Procedures</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Neuroendoscopy</term>
<term>Neuronavigation</term>
<term>Neurosurgical Procedures</term>
<term>Ventriculostomy</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en"><term>Cerebral Ventricles</term>
<term>Dura Mater</term>
<term>Hypothalamus</term>
<term>Septum Pellucidum</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Cadaver</term>
<term>Clinical Competence</term>
<term>Feasibility Studies</term>
<term>Humans</term>
<term>Laminectomy</term>
<term>Learning Curve</term>
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<front><div type="abstract" xml:lang="en">Cadaveric surgical simulation carries the advantage of realistic anatomy and haptic feedback but has been historically difficult to model for intraventricular approaches given the need for active flow of CSF. This feasibility study was designed to simulate intraventricular neuroendoscopic approaches and techniques by reconstituting natural CSF flow in a cadaveric model. In 10 fresh human cadavers, a simple cervical laminectomy and dural opening were made, and a 12-gauge arterial catheter was introduced. Saline was continuously perfused at physiological CSF pressures to reconstitute the subarachnoid space and ventricles. A neuroendoscope was subsequently inserted via a standard right frontal bur hole. In 8 of the 10 cadavers, adequate reconstitution and endoscopic access of the lateral and third ventricles were achieved. In 2 cadavers, ventricular access was not feasible, perhaps because of a small ventricle size and/or deteriorated tissue quality. In all 8 cadavers with successful CSF flow reconstitution and endoscopic access, identifying the foramen of Monro was possible, as was performing septum pellucidotomy and endoscopic third ventriculostomy. Furthermore, navigation of the cerebral aqueduct, fourth ventricle, prepontine cistern, and suprasellar cistern via the lamina terminalis was possible, providing a complementary educational paradigm for resident education that cannot typically be performed in live surgery. Surgical simulation plays a critical and increasingly prominent role in surgical education, particularly for techniques with steep learning curves including intraventricular neuroendoscopic procedures. This novel model provides feasible and realistic surgical simulation of neuroendoscopic intraventricular procedures and approaches.</div>
</front>
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<Title>Journal of neurosurgery</Title>
<ISOAbbreviation>J. Neurosurg.</ISOAbbreviation>
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<ArticleTitle>Cerebrospinal fluid reconstitution via a perfusion-based cadaveric model: feasibility study demonstrating surgical simulation of neuroendoscopic procedures.</ArticleTitle>
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<Abstract><AbstractText>Cadaveric surgical simulation carries the advantage of realistic anatomy and haptic feedback but has been historically difficult to model for intraventricular approaches given the need for active flow of CSF. This feasibility study was designed to simulate intraventricular neuroendoscopic approaches and techniques by reconstituting natural CSF flow in a cadaveric model. In 10 fresh human cadavers, a simple cervical laminectomy and dural opening were made, and a 12-gauge arterial catheter was introduced. Saline was continuously perfused at physiological CSF pressures to reconstitute the subarachnoid space and ventricles. A neuroendoscope was subsequently inserted via a standard right frontal bur hole. In 8 of the 10 cadavers, adequate reconstitution and endoscopic access of the lateral and third ventricles were achieved. In 2 cadavers, ventricular access was not feasible, perhaps because of a small ventricle size and/or deteriorated tissue quality. In all 8 cadavers with successful CSF flow reconstitution and endoscopic access, identifying the foramen of Monro was possible, as was performing septum pellucidotomy and endoscopic third ventriculostomy. Furthermore, navigation of the cerebral aqueduct, fourth ventricle, prepontine cistern, and suprasellar cistern via the lamina terminalis was possible, providing a complementary educational paradigm for resident education that cannot typically be performed in live surgery. Surgical simulation plays a critical and increasingly prominent role in surgical education, particularly for techniques with steep learning curves including intraventricular neuroendoscopic procedures. This novel model provides feasible and realistic surgical simulation of neuroendoscopic intraventricular procedures and approaches.</AbstractText>
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<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Winer</LastName>
<ForeName>Jesse L</ForeName>
<Initials>JL</Initials>
<AffiliationInfo><Affiliation>Departments of 1 Neurosurgery and.</Affiliation>
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<Author ValidYN="Y"><LastName>Kramer</LastName>
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<Author ValidYN="Y"><LastName>Ohiorhenuan</LastName>
<ForeName>Ifije</ForeName>
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<Author ValidYN="Y"><LastName>Minneti</LastName>
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<Initials>M</Initials>
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<Author ValidYN="Y"><LastName>Giannotta</LastName>
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<Initials>S</Initials>
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</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Zada</LastName>
<ForeName>Gabriel</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>Departments of 1 Neurosurgery and.</Affiliation>
</AffiliationInfo>
</Author>
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<ArticleDate DateType="Electronic"><Year>2015</Year>
<Month>04</Month>
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<MeshHeadingList><MeshHeading><DescriptorName MajorTopicYN="N" UI="D002102">Cadaver</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D002552">Cerebral Ventricles</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000033">anatomy & histology</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000601">surgery</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D002555">Cerebrospinal Fluid</DescriptorName>
<QualifierName MajorTopicYN="Y" UI="Q000737">chemistry</QualifierName>
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<MeshHeading><DescriptorName MajorTopicYN="N" UI="D002983">Clinical Competence</DescriptorName>
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<MeshHeading><DescriptorName MajorTopicYN="N" UI="D004388">Dura Mater</DescriptorName>
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<QualifierName MajorTopicYN="N" UI="Q000601">surgery</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D005240">Feasibility Studies</DescriptorName>
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<MeshHeading><DescriptorName MajorTopicYN="N" UI="D006801">Humans</DescriptorName>
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<MeshHeading><DescriptorName MajorTopicYN="N" UI="D007031">Hypothalamus</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000033">anatomy & histology</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000601">surgery</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D007796">Laminectomy</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D059032">Learning Curve</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D044583">Neuroendoscopy</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000193">education</QualifierName>
<QualifierName MajorTopicYN="Y" UI="Q000379">methods</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D038361">Neuronavigation</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000193">education</QualifierName>
<QualifierName MajorTopicYN="Y" UI="Q000379">methods</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D019635">Neurosurgical Procedures</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000193">education</QualifierName>
<QualifierName MajorTopicYN="Y" UI="Q000379">methods</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D012688">Septum Pellucidum</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000033">anatomy & histology</QualifierName>
<QualifierName MajorTopicYN="N" UI="Q000601">surgery</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N" UI="D014696">Ventriculostomy</DescriptorName>
<QualifierName MajorTopicYN="N" UI="Q000379">methods</QualifierName>
</MeshHeading>
</MeshHeadingList>
<KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">ETV = endoscopic third ventriculostomy</Keyword>
<Keyword MajorTopicYN="N">FTDL = Fresh Tissue Dissection Laboratory</Keyword>
<Keyword MajorTopicYN="N">USC = University of Southern California</Keyword>
<Keyword MajorTopicYN="N">cadaver</Keyword>
<Keyword MajorTopicYN="N">cerebrospinal fluid</Keyword>
<Keyword MajorTopicYN="N">endoscopy</Keyword>
<Keyword MajorTopicYN="N">simulation</Keyword>
<Keyword MajorTopicYN="N">surgical technique</Keyword>
<Keyword MajorTopicYN="N">surgical training</Keyword>
<Keyword MajorTopicYN="N">third ventriculostomy</Keyword>
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<name sortKey="Ohiorhenuan, Ifije" sort="Ohiorhenuan, Ifije" uniqKey="Ohiorhenuan I" first="Ifije" last="Ohiorhenuan">Ifije Ohiorhenuan</name>
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<name sortKey="Winer, Jesse L" sort="Winer, Jesse L" uniqKey="Winer J" first="Jesse L" last="Winer">Jesse L. Winer</name>
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<country name="États-Unis"><region name="Californie"><name sortKey="Minneti, Michael" sort="Minneti, Michael" uniqKey="Minneti M" first="Michael" last="Minneti">Michael Minneti</name>
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