Threat-related learning relies on distinct dorsal prefrontal cortex network connectivity
Identifieur interne : 001A96 ( Pmc/Corpus ); précédent : 001A95; suivant : 001A97Threat-related learning relies on distinct dorsal prefrontal cortex network connectivity
Auteurs : M. D. Wheelock ; K. R. Sreenivasan ; K. H. Wood ; L. W. Ver Hoef ; G. Deshpande ; D. C. KnightSource :
- NeuroImage [ 1053-8119 ] ; 2014.
Abstract
Conditioned changes in the emotional response to threat (e.g. aversive unconditioned stimulus; UCS) are mediated in part by the prefrontal cortex (PFC). Unpredictable threats elicit large emotional responses, while the response is diminished when the threat is predictable. A better understanding of how PFC connectivity to other brain regions varies with threat predictability would provide important insights into the neural processes that mediate conditioned diminution of the emotional response to threat. The present study examined brain connectivity during predictable and unpredictable threat exposure using a fear conditioning paradigm (previously published in
Url:
DOI: 10.1016/j.neuroimage.2014.08.005
PubMed: 25111474
PubMed Central: 4252829
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