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Quantitative upper airway endoscopy with swept-source anatomical optical coherence tomography

Identifieur interne : 001303 ( Pmc/Corpus ); précédent : 001302; suivant : 001304

Quantitative upper airway endoscopy with swept-source anatomical optical coherence tomography

Auteurs : Kushal Wijesundara ; Carlton Zdanski ; Julia Kimbell ; Hillel Price ; Nicusor Iftimia ; Amy L. Oldenburg

Source :

RBID : PMC:3959831

Abstract

Minimally invasive imaging of upper airway obstructions in children and adults is needed to improve clinical decision-making. Toward this goal, we demonstrate an anatomical optical coherence tomography (aOCT) system delivered via a small-bore, flexible endoscope to quantify the upper airway lumen geometry. Helical scans were obtained from a proximally-scanned fiber-optic catheter of 820 μm outer diameter and >2 mm focal length. Coupled with a long coherence length wavelength-swept light source, the system exhibited an SNR roll-off of < 10 dB over a 10 mm range. Operating at 10 rotations/s, the average accuracy of segmented cross-sectional areas was found to be −1.4 ± 1.0%. To demonstrate the capability of this system, aOCT was performed on a pediatric airway phantom and on ex vivo swine trachea. The ability for quantitative endoscopy afforded by this system can aid in diagnosis, medical and surgical decision making, and predictive modeling of upper airway obstructive disorders.


Url:
DOI: 10.1364/BOE.5.000788
PubMed: 24688814
PubMed Central: 3959831

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