A robotic platform to assess, guide and perturb rat forelimb movements.
Identifieur interne : 002444 ( Ncbi/Curation ); précédent : 002443; suivant : 002445A robotic platform to assess, guide and perturb rat forelimb movements.
Auteurs : Bogdan C. Vigaru ; Olivier Lambercy ; Maximilian Schubring-Giese ; Jonas A. Hosp ; Melanie Schneider ; Clement Osei-Atiemo ; Andreas Luft ; Roger GassertSource :
- IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society [ 1558-0210 ] ; 2013.
English descriptors
- KwdEn :
- MESH :
Abstract
Animal models are widely used to explore the mechanisms underlying sensorimotor control and learning. However, current experimental paradigms allow only limited control over task difficulty and cannot provide detailed information on forelimb kinematics and dynamics. Here we propose a novel robotic device for use in motor learning investigations with rats. The compact, highly transparent, three degree-of-freedom manipulandum is capable of rendering nominal forces of 2 N to guide or perturb rat forelimb movements, while providing objective and quantitative assessments of endpoint motor performance in a 50×30 mm(2) planar workspace. Preliminary experiments with six healthy rats show that the animals can be familiarized with the experimental setup and are able to grasp and manipulate the end-effector of the robot. Further, dynamic perturbations and guiding force fields (i.e., haptic tunnels) rendered by the device had significant influence on rat motor behavior (ANOVA, ). This approach opens up new research avenues for future characterizations of motor learning stages, both in healthy and in stroke models.
DOI: 10.1109/TNSRE.2013.2240014
PubMed: 23335672
Links toward previous steps (curation, corpus...)
- to stream PubMed, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000A46
- to stream PubMed, to step Curation: Pour aller vers cette notice dans l'étape Curation :000A46
- to stream PubMed, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000977
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :002444
Links to Exploration step
pubmed:23335672Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">A robotic platform to assess, guide and perturb rat forelimb movements.</title>
<author><name sortKey="Vigaru, Bogdan C" sort="Vigaru, Bogdan C" uniqKey="Vigaru B" first="Bogdan C" last="Vigaru">Bogdan C. Vigaru</name>
</author>
<author><name sortKey="Lambercy, Olivier" sort="Lambercy, Olivier" uniqKey="Lambercy O" first="Olivier" last="Lambercy">Olivier Lambercy</name>
</author>
<author><name sortKey="Schubring Giese, Maximilian" sort="Schubring Giese, Maximilian" uniqKey="Schubring Giese M" first="Maximilian" last="Schubring-Giese">Maximilian Schubring-Giese</name>
</author>
<author><name sortKey="Hosp, Jonas A" sort="Hosp, Jonas A" uniqKey="Hosp J" first="Jonas A" last="Hosp">Jonas A. Hosp</name>
</author>
<author><name sortKey="Schneider, Melanie" sort="Schneider, Melanie" uniqKey="Schneider M" first="Melanie" last="Schneider">Melanie Schneider</name>
</author>
<author><name sortKey="Osei Atiemo, Clement" sort="Osei Atiemo, Clement" uniqKey="Osei Atiemo C" first="Clement" last="Osei-Atiemo">Clement Osei-Atiemo</name>
</author>
<author><name sortKey="Luft, Andreas" sort="Luft, Andreas" uniqKey="Luft A" first="Andreas" last="Luft">Andreas Luft</name>
</author>
<author><name sortKey="Gassert, Roger" sort="Gassert, Roger" uniqKey="Gassert R" first="Roger" last="Gassert">Roger Gassert</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="2013">2013</date>
<idno type="doi">10.1109/TNSRE.2013.2240014</idno>
<idno type="RBID">pubmed:23335672</idno>
<idno type="pmid">23335672</idno>
<idno type="wicri:Area/PubMed/Corpus">000A46</idno>
<idno type="wicri:Area/PubMed/Curation">000A46</idno>
<idno type="wicri:Area/PubMed/Checkpoint">000977</idno>
<idno type="wicri:Area/Ncbi/Merge">002444</idno>
<idno type="wicri:Area/Ncbi/Curation">002444</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">A robotic platform to assess, guide and perturb rat forelimb movements.</title>
<author><name sortKey="Vigaru, Bogdan C" sort="Vigaru, Bogdan C" uniqKey="Vigaru B" first="Bogdan C" last="Vigaru">Bogdan C. Vigaru</name>
</author>
<author><name sortKey="Lambercy, Olivier" sort="Lambercy, Olivier" uniqKey="Lambercy O" first="Olivier" last="Lambercy">Olivier Lambercy</name>
</author>
<author><name sortKey="Schubring Giese, Maximilian" sort="Schubring Giese, Maximilian" uniqKey="Schubring Giese M" first="Maximilian" last="Schubring-Giese">Maximilian Schubring-Giese</name>
</author>
<author><name sortKey="Hosp, Jonas A" sort="Hosp, Jonas A" uniqKey="Hosp J" first="Jonas A" last="Hosp">Jonas A. Hosp</name>
</author>
<author><name sortKey="Schneider, Melanie" sort="Schneider, Melanie" uniqKey="Schneider M" first="Melanie" last="Schneider">Melanie Schneider</name>
</author>
<author><name sortKey="Osei Atiemo, Clement" sort="Osei Atiemo, Clement" uniqKey="Osei Atiemo C" first="Clement" last="Osei-Atiemo">Clement Osei-Atiemo</name>
</author>
<author><name sortKey="Luft, Andreas" sort="Luft, Andreas" uniqKey="Luft A" first="Andreas" last="Luft">Andreas Luft</name>
</author>
<author><name sortKey="Gassert, Roger" sort="Gassert, Roger" uniqKey="Gassert R" first="Roger" last="Gassert">Roger Gassert</name>
</author>
</analytic>
<series><title level="j">IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society</title>
<idno type="eISSN">1558-0210</idno>
<imprint><date when="2013" type="published">2013</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Algorithms</term>
<term>Animals</term>
<term>Biomechanical Phenomena</term>
<term>Data Interpretation, Statistical</term>
<term>Electronics</term>
<term>Environment</term>
<term>Equipment Design</term>
<term>Forelimb (physiology)</term>
<term>Learning (physiology)</term>
<term>Male</term>
<term>Motor Skills</term>
<term>Movement (physiology)</term>
<term>Rats</term>
<term>Rats, Long-Evans</term>
<term>Robotics</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Forelimb</term>
<term>Learning</term>
<term>Movement</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Algorithms</term>
<term>Animals</term>
<term>Biomechanical Phenomena</term>
<term>Data Interpretation, Statistical</term>
<term>Electronics</term>
<term>Environment</term>
<term>Equipment Design</term>
<term>Male</term>
<term>Motor Skills</term>
<term>Rats</term>
<term>Rats, Long-Evans</term>
<term>Robotics</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Animal models are widely used to explore the mechanisms underlying sensorimotor control and learning. However, current experimental paradigms allow only limited control over task difficulty and cannot provide detailed information on forelimb kinematics and dynamics. Here we propose a novel robotic device for use in motor learning investigations with rats. The compact, highly transparent, three degree-of-freedom manipulandum is capable of rendering nominal forces of 2 N to guide or perturb rat forelimb movements, while providing objective and quantitative assessments of endpoint motor performance in a 50×30 mm(2) planar workspace. Preliminary experiments with six healthy rats show that the animals can be familiarized with the experimental setup and are able to grasp and manipulate the end-effector of the robot. Further, dynamic perturbations and guiding force fields (i.e., haptic tunnels) rendered by the device had significant influence on rat motor behavior (ANOVA, ). This approach opens up new research avenues for future characterizations of motor learning stages, both in healthy and in stroke models.</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/HapticV1/Data/Ncbi/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002444 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 002444 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Ticri/CIDE |area= HapticV1 |flux= Ncbi |étape= Curation |type= RBID |clé= pubmed:23335672 |texte= A robotic platform to assess, guide and perturb rat forelimb movements. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i -Sk "pubmed:23335672" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \ | NlmPubMed2Wicri -a HapticV1
![]() | This area was generated with Dilib version V0.6.23. | ![]() |