Dietary Blueberry and Bifidobacteria Attenuate Nonalcoholic Fatty Liver Disease in Rats by Affecting SIRT1-Mediated Signaling Pathway
Identifieur interne : 003578 ( Ncbi/Checkpoint ); précédent : 003577; suivant : 003579Dietary Blueberry and Bifidobacteria Attenuate Nonalcoholic Fatty Liver Disease in Rats by Affecting SIRT1-Mediated Signaling Pathway
Auteurs : Tingting Ren [République populaire de Chine] ; Chao Huang [République populaire de Chine] ; Mingliang Cheng [République populaire de Chine]Source :
- Oxidative Medicine and Cellular Longevity [ 1942-0900 ] ; 2014.
Abstract
NAFLD model rats were established and divided into NAFLD model (MG group), SIRT1 RNAi (SI group), blueberry juice (BJ group), blueberry juice + bifidobacteria (BJB group), blueberry juice + SIRT1 RNAi (BJSI group), and blueberry juice + bifidobacteria + SIRT1 RNAi groups (BJBSI group). A group with normal rats was a control group (CG). BJB group ameliorated NAFLD, which was better than BJ group (
Url:
DOI: 10.1155/2014/469059
PubMed: 25544867
PubMed Central: 4265704
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Dietary Blueberry and Bifidobacteria Attenuate Nonalcoholic Fatty Liver Disease in Rats by Affecting SIRT1-Mediated Signaling Pathway</title><author><name sortKey="Ren, Tingting" sort="Ren, Tingting" uniqKey="Ren T" first="Tingting" last="Ren">Tingting Ren</name><affiliation wicri:level="1"><nlm:aff id="I1">Biochemistry Department, Affiliated Hospital of Guiyang Medical College, Guiyang, Guizhou 550004, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Biochemistry Department, Affiliated Hospital of Guiyang Medical College, Guiyang, Guizhou 550004</wicri:regionArea><wicri:noRegion>Guizhou 550004</wicri:noRegion></affiliation></author><author><name sortKey="Huang, Chao" sort="Huang, Chao" uniqKey="Huang C" first="Chao" last="Huang">Chao Huang</name><affiliation wicri:level="1"><nlm:aff id="I2">Guiyang Medical College, Guiyang, Guizhou 550004, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Guiyang Medical College, Guiyang, Guizhou 550004</wicri:regionArea><wicri:noRegion>Guizhou 550004</wicri:noRegion></affiliation></author><author><name sortKey="Cheng, Mingliang" sort="Cheng, Mingliang" uniqKey="Cheng M" first="Mingliang" last="Cheng">Mingliang Cheng</name><affiliation wicri:level="1"><nlm:aff id="I3">Department of Infectious Diseases, Affiliated Hospital of Guiyang Medical College, 28 Guiyi Street, Guiyang, Guizhou 550004, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Infectious Diseases, Affiliated Hospital of Guiyang Medical College, 28 Guiyi Street, Guiyang, Guizhou 550004</wicri:regionArea><wicri:noRegion>Guizhou 550004</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25544867</idno><idno type="pmc">4265704</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265704</idno><idno type="RBID">PMC:4265704</idno><idno type="doi">10.1155/2014/469059</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">002150</idno><idno type="wicri:Area/Pmc/Curation">002150</idno><idno type="wicri:Area/Pmc/Checkpoint">000D04</idno><idno type="wicri:Area/Ncbi/Merge">003578</idno><idno type="wicri:Area/Ncbi/Curation">003578</idno><idno type="wicri:Area/Ncbi/Checkpoint">003578</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Dietary Blueberry and Bifidobacteria Attenuate Nonalcoholic Fatty Liver Disease in Rats by Affecting SIRT1-Mediated Signaling Pathway</title><author><name sortKey="Ren, Tingting" sort="Ren, Tingting" uniqKey="Ren T" first="Tingting" last="Ren">Tingting Ren</name><affiliation wicri:level="1"><nlm:aff id="I1">Biochemistry Department, Affiliated Hospital of Guiyang Medical College, Guiyang, Guizhou 550004, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Biochemistry Department, Affiliated Hospital of Guiyang Medical College, Guiyang, Guizhou 550004</wicri:regionArea><wicri:noRegion>Guizhou 550004</wicri:noRegion></affiliation></author><author><name sortKey="Huang, Chao" sort="Huang, Chao" uniqKey="Huang C" first="Chao" last="Huang">Chao Huang</name><affiliation wicri:level="1"><nlm:aff id="I2">Guiyang Medical College, Guiyang, Guizhou 550004, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Guiyang Medical College, Guiyang, Guizhou 550004</wicri:regionArea><wicri:noRegion>Guizhou 550004</wicri:noRegion></affiliation></author><author><name sortKey="Cheng, Mingliang" sort="Cheng, Mingliang" uniqKey="Cheng M" first="Mingliang" last="Cheng">Mingliang Cheng</name><affiliation wicri:level="1"><nlm:aff id="I3">Department of Infectious Diseases, Affiliated Hospital of Guiyang Medical College, 28 Guiyi Street, Guiyang, Guizhou 550004, China</nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Infectious Diseases, Affiliated Hospital of Guiyang Medical College, 28 Guiyi Street, Guiyang, Guizhou 550004</wicri:regionArea><wicri:noRegion>Guizhou 550004</wicri:noRegion></affiliation></author></analytic><series><title level="j">Oxidative Medicine and Cellular Longevity</title><idno type="ISSN">1942-0900</idno><idno type="eISSN">1942-0994</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>NAFLD model rats were established and divided into NAFLD model (MG group), SIRT1 RNAi (SI group), blueberry juice (BJ group), blueberry juice + bifidobacteria (BJB group), blueberry juice + SIRT1 RNAi (BJSI group), and blueberry juice + bifidobacteria + SIRT1 RNAi groups (BJBSI group). A group with normal rats was a control group (CG). BJB group ameliorated NAFLD, which was better than BJ group (<italic>P</italic> < 0.05). The lipid accumulation was lower in CG, BJ, and BJB groups than that in MG, SI, BJSI, and BJBSI groups (<italic>P</italic> < 0.05). The levels of SIRT1 and PPAR-<italic>α</italic> were higher in CG, BJ, and BJB groups than those in MG, SI, BJSI, and BJBSI groups (<italic>P</italic> < 0.05). The levels of SREBP-1c were lower in CG, BJ, and BJB groups than those in MG, SI, BJSI, and BJBSI groups (<italic>P</italic> < 0.05). The biochemical indexes SOD, GSH, and HDL-c were improved from CG to BJB group (<italic>P</italic> < 0.05). Inversely, the levels of AST and ALT, TG, TC, LDL-c, and MDA were decreased from CG to BJB group (<italic>P</italic> < 0.05). These changes enhance antioxidative capability and biochemical index of rats. 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Van Bergenhenegouwen</name></author><author><name sortKey="Etal" uniqKey="Etal">ETAL</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Ren, Tingting" sort="Ren, Tingting" uniqKey="Ren T" first="Tingting" last="Ren">Tingting Ren</name></noRegion><name sortKey="Cheng, Mingliang" sort="Cheng, Mingliang" uniqKey="Cheng M" first="Mingliang" last="Cheng">Mingliang Cheng</name><name sortKey="Huang, Chao" sort="Huang, Chao" uniqKey="Huang C" first="Chao" last="Huang">Chao Huang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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