[Intraocular lens as a drug delivery device].
Identifieur interne : 002862 ( Ncbi/Checkpoint ); précédent : 002861; suivant : 002863[Intraocular lens as a drug delivery device].
Auteurs : K H Eibl-Lindner [Allemagne] ; R. Liegl ; C. Wertheimer ; A. KampikSource :
- Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft [ 1433-0423 ] ; 2013.
English descriptors
- KwdEn :
- MESH :
- chemical , administration & dosage : Anti-Inflammatory Agents, Drug Implants, Ophthalmic Solutions.
- drug therapy : Capsule Opacification, Endophthalmitis.
- Humans, Lenses, Intraocular, Prosthesis Design.
Abstract
The development of an intraocular lens (IOL) as a drug delivery device has been the purpose of numerous preclinical studies and might become a future technology in cataract surgery. There are three techniques of pharmacological IOL modification: surface modification (coating), optic modification (soaking) or haptic modification with a slow-release-system. The therapeutic goals are endophthalmitis, postoperative inflammation and posterior capsule opacification.
DOI: 10.1007/s00347-013-2904-0
PubMed: 23933838
Affiliations:
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pubmed:23933838Le document en format XML
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<author><name sortKey="Eibl Lindner, K H" sort="Eibl Lindner, K H" uniqKey="Eibl Lindner K" first="K H" last="Eibl-Lindner">K H Eibl-Lindner</name>
<affiliation wicri:level="1"><nlm:affiliation>Augenklinik, LMU München, Campus Innenstadt, Mathildenstr. 8, 80336, München, Deutschland, Kirsten.Eibl@med.uni-muenchen.de.</nlm:affiliation>
<country wicri:rule="url">Allemagne</country>
<wicri:regionArea>Augenklinik, LMU München, Campus Innenstadt, Mathildenstr. 8, 80336, München, Deutschland</wicri:regionArea>
<wicri:noRegion>Deutschland</wicri:noRegion>
<wicri:noRegion>Deutschland</wicri:noRegion>
<wicri:noRegion>Deutschland</wicri:noRegion>
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<author><name sortKey="Liegl, R" sort="Liegl, R" uniqKey="Liegl R" first="R" last="Liegl">R. Liegl</name>
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<author><name sortKey="Wertheimer, C" sort="Wertheimer, C" uniqKey="Wertheimer C" first="C" last="Wertheimer">C. Wertheimer</name>
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<author><name sortKey="Kampik, A" sort="Kampik, A" uniqKey="Kampik A" first="A" last="Kampik">A. Kampik</name>
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<idno type="doi">10.1007/s00347-013-2904-0</idno>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">[Intraocular lens as a drug delivery device].</title>
<author><name sortKey="Eibl Lindner, K H" sort="Eibl Lindner, K H" uniqKey="Eibl Lindner K" first="K H" last="Eibl-Lindner">K H Eibl-Lindner</name>
<affiliation wicri:level="1"><nlm:affiliation>Augenklinik, LMU München, Campus Innenstadt, Mathildenstr. 8, 80336, München, Deutschland, Kirsten.Eibl@med.uni-muenchen.de.</nlm:affiliation>
<country wicri:rule="url">Allemagne</country>
<wicri:regionArea>Augenklinik, LMU München, Campus Innenstadt, Mathildenstr. 8, 80336, München, Deutschland</wicri:regionArea>
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<author><name sortKey="Liegl, R" sort="Liegl, R" uniqKey="Liegl R" first="R" last="Liegl">R. Liegl</name>
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<author><name sortKey="Wertheimer, C" sort="Wertheimer, C" uniqKey="Wertheimer C" first="C" last="Wertheimer">C. Wertheimer</name>
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<author><name sortKey="Kampik, A" sort="Kampik, A" uniqKey="Kampik A" first="A" last="Kampik">A. Kampik</name>
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<series><title level="j">Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft</title>
<idno type="eISSN">1433-0423</idno>
<imprint><date when="2013" type="published">2013</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anti-Inflammatory Agents (administration & dosage)</term>
<term>Capsule Opacification (drug therapy)</term>
<term>Drug Implants (administration & dosage)</term>
<term>Endophthalmitis (drug therapy)</term>
<term>Humans</term>
<term>Lenses, Intraocular</term>
<term>Ophthalmic Solutions (administration & dosage)</term>
<term>Prosthesis Design</term>
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<keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Anti-Inflammatory Agents</term>
<term>Drug Implants</term>
<term>Ophthalmic Solutions</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Capsule Opacification</term>
<term>Endophthalmitis</term>
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<keywords scheme="MESH" xml:lang="en"><term>Humans</term>
<term>Lenses, Intraocular</term>
<term>Prosthesis Design</term>
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<front><div type="abstract" xml:lang="en">The development of an intraocular lens (IOL) as a drug delivery device has been the purpose of numerous preclinical studies and might become a future technology in cataract surgery. There are three techniques of pharmacological IOL modification: surface modification (coating), optic modification (soaking) or haptic modification with a slow-release-system. The therapeutic goals are endophthalmitis, postoperative inflammation and posterior capsule opacification.</div>
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<affiliations><list><country><li>Allemagne</li>
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<tree><noCountry><name sortKey="Kampik, A" sort="Kampik, A" uniqKey="Kampik A" first="A" last="Kampik">A. Kampik</name>
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<name sortKey="Wertheimer, C" sort="Wertheimer, C" uniqKey="Wertheimer C" first="C" last="Wertheimer">C. Wertheimer</name>
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<country name="Allemagne"><noRegion><name sortKey="Eibl Lindner, K H" sort="Eibl Lindner, K H" uniqKey="Eibl Lindner K" first="K H" last="Eibl-Lindner">K H Eibl-Lindner</name>
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