Neural and behavioral correlates of drawing in an early blind painter : A case study
Identifieur interne : 005325 ( Main/Merge ); précédent : 005324; suivant : 005326Neural and behavioral correlates of drawing in an early blind painter : A case study
Auteurs : Amir Amedi [États-Unis, Israël] ; Lotfi B. Merabet [États-Unis] ; Joan Camprodon [États-Unis] ; Felix Bermpohl [États-Unis, Allemagne] ; Sharon Fox [États-Unis] ; Itamar Ronen [États-Unis] ; Dae-Shik Kim [États-Unis] ; Alvaro Pascual-Leone [États-Unis]Source :
- Brain research [ 0006-8993 ] ; 2008.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Homme.
English descriptors
- KwdEn :
Abstract
Humans rely heavily on vision to identify objects in the world and can create mental representations of the objects they encounter. Objects can also be identified and mentally represented through haptic exploration. However, it is unclear whether prior visual experience is necessary to generate these internal representations. Subject EA, an early blind artist, provides insight into this question. Like other blind individuals, EA captures the external world by touch. However, he is also able to reveal his internal representations through highly detailed drawings that are unequivocally understandable by a sighted person. We employed fMRI to investigate the neural correlates associated with EA's ability to transform tactilely explored three-dimensional objects into drawings and contrasted these findings with a series of control conditions (e.g. nonsensical scribbling as a sensory-motor control). Activation during drawing (compared to scribbling) occurred in brain areas normally associated with vision, including the striate cortex along with frontal and parietal cortical regions. Some of these areas showed overlap when EA was asked to mentally imagine the pictures he had to draw (albeit to a lesser anatomical extent and signal magnitude). These results have important implications as regards our understanding of the ways in which tactile information can generate mental representations of shapes and scenes in the absence of normal visual development. Furthermore, these findings suggest the occipital cortex plays a key role in supporting mental representations even without prior visual experience.
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: 000817
- to stream PascalFrancis, to step Curation: 000C15
- to stream PascalFrancis, to step Checkpoint: 000691
Links to Exploration step
Pascal:09-0115567Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Neural and behavioral correlates of drawing in an early blind painter : A case study</title>
<author><name sortKey="Amedi, Amir" sort="Amedi, Amir" uniqKey="Amedi A" first="Amir" last="Amedi">Amir Amedi</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School</s1>
<s2>Boston, MA 02115</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Physiology, Faculty of Medicine and Program of Cognitive Science, The Hebrew University of Jerusalem</s1>
<s2>Jerusalem 91220</s2>
<s3>ISR</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
<country>Israël</country>
<wicri:noRegion>Jerusalem 91220</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Merabet, Lotfi B" sort="Merabet, Lotfi B" uniqKey="Merabet L" first="Lotfi B." last="Merabet">Lotfi B. Merabet</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School</s1>
<s2>Boston, MA 02115</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Camprodon, Joan" sort="Camprodon, Joan" uniqKey="Camprodon J" first="Joan" last="Camprodon">Joan Camprodon</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School</s1>
<s2>Boston, MA 02115</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bermpohl, Felix" sort="Bermpohl, Felix" uniqKey="Bermpohl F" first="Felix" last="Bermpohl">Felix Bermpohl</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School</s1>
<s2>Boston, MA 02115</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Department of Psychiatry and Psychotherapy, Charité -University Medicine Berlin, Campus Mitte</s1>
<s2>Berlin</s2>
<s3>DEU</s3>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<placeName><region type="land" nuts="3">Berlin</region>
<settlement type="city">Berlin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Fox, Sharon" sort="Fox, Sharon" uniqKey="Fox S" first="Sharon" last="Fox">Sharon Fox</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School</s1>
<s2>Boston, MA 02115</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ronen, Itamar" sort="Ronen, Itamar" uniqKey="Ronen I" first="Itamar" last="Ronen">Itamar Ronen</name>
<affiliation wicri:level="2"><inist:fA14 i1="04"><s1>Center for Biomedical Imaging and Department of Anatomy and Neurobiology, Boston University School of Medicine</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kim, Dae Shik" sort="Kim, Dae Shik" uniqKey="Kim D" first="Dae-Shik" last="Kim">Dae-Shik Kim</name>
<affiliation wicri:level="2"><inist:fA14 i1="04"><s1>Center for Biomedical Imaging and Department of Anatomy and Neurobiology, Boston University School of Medicine</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Pascual Leone, Alvaro" sort="Pascual Leone, Alvaro" uniqKey="Pascual Leone A" first="Alvaro" last="Pascual-Leone">Alvaro Pascual-Leone</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School</s1>
<s2>Boston, MA 02115</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">09-0115567</idno>
<date when="2008">2008</date>
<idno type="stanalyst">PASCAL 09-0115567 INIST</idno>
<idno type="RBID">Pascal:09-0115567</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000817</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000C15</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">000691</idno>
<idno type="wicri:doubleKey">0006-8993:2008:Amedi A:neural:and:behavioral</idno>
<idno type="wicri:Area/Main/Merge">005325</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Neural and behavioral correlates of drawing in an early blind painter : A case study</title>
<author><name sortKey="Amedi, Amir" sort="Amedi, Amir" uniqKey="Amedi A" first="Amir" last="Amedi">Amir Amedi</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School</s1>
<s2>Boston, MA 02115</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of Physiology, Faculty of Medicine and Program of Cognitive Science, The Hebrew University of Jerusalem</s1>
<s2>Jerusalem 91220</s2>
<s3>ISR</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
<country>Israël</country>
<wicri:noRegion>Jerusalem 91220</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Merabet, Lotfi B" sort="Merabet, Lotfi B" uniqKey="Merabet L" first="Lotfi B." last="Merabet">Lotfi B. Merabet</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School</s1>
<s2>Boston, MA 02115</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Camprodon, Joan" sort="Camprodon, Joan" uniqKey="Camprodon J" first="Joan" last="Camprodon">Joan Camprodon</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School</s1>
<s2>Boston, MA 02115</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Bermpohl, Felix" sort="Bermpohl, Felix" uniqKey="Bermpohl F" first="Felix" last="Bermpohl">Felix Bermpohl</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School</s1>
<s2>Boston, MA 02115</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
<affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Department of Psychiatry and Psychotherapy, Charité -University Medicine Berlin, Campus Mitte</s1>
<s2>Berlin</s2>
<s3>DEU</s3>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Allemagne</country>
<placeName><region type="land" nuts="3">Berlin</region>
<settlement type="city">Berlin</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Fox, Sharon" sort="Fox, Sharon" uniqKey="Fox S" first="Sharon" last="Fox">Sharon Fox</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School</s1>
<s2>Boston, MA 02115</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ronen, Itamar" sort="Ronen, Itamar" uniqKey="Ronen I" first="Itamar" last="Ronen">Itamar Ronen</name>
<affiliation wicri:level="2"><inist:fA14 i1="04"><s1>Center for Biomedical Imaging and Department of Anatomy and Neurobiology, Boston University School of Medicine</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kim, Dae Shik" sort="Kim, Dae Shik" uniqKey="Kim D" first="Dae-Shik" last="Kim">Dae-Shik Kim</name>
<affiliation wicri:level="2"><inist:fA14 i1="04"><s1>Center for Biomedical Imaging and Department of Anatomy and Neurobiology, Boston University School of Medicine</s1>
<s2>Boston, MA</s2>
<s3>USA</s3>
<sZ>6 aut.</sZ>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Pascual Leone, Alvaro" sort="Pascual Leone, Alvaro" uniqKey="Pascual Leone A" first="Alvaro" last="Pascual-Leone">Alvaro Pascual-Leone</name>
<affiliation wicri:level="2"><inist:fA14 i1="01"><s1>Berenson-Allen Center for Noninvasive Brain Stimulation, Beth Israel Deaconess Medical Center, Harvard Medical School</s1>
<s2>Boston, MA 02115</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>États-Unis</country>
<placeName><region type="state">Massachusetts</region>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Brain research</title>
<title level="j" type="abbreviated">Brain res.</title>
<idno type="ISSN">0006-8993</idno>
<imprint><date when="2008">2008</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Brain research</title>
<title level="j" type="abbreviated">Brain res.</title>
<idno type="ISSN">0006-8993</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Behavior</term>
<term>Blind</term>
<term>Blindness</term>
<term>Brain plasticity</term>
<term>Case study</term>
<term>Early</term>
<term>Human</term>
<term>Memory</term>
<term>Multisensory integration</term>
<term>Perception</term>
<term>Recognition</term>
<term>Tactile sensitivity</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Comportement</term>
<term>Précoce</term>
<term>Aveugle</term>
<term>Etude cas</term>
<term>Sensibilité tactile</term>
<term>Perception</term>
<term>Mémoire</term>
<term>Reconnaissance</term>
<term>Cécité</term>
<term>Intégration multisensorielle</term>
<term>Homme</term>
<term>Plasticité cérébrale</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Homme</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Humans rely heavily on vision to identify objects in the world and can create mental representations of the objects they encounter. Objects can also be identified and mentally represented through haptic exploration. However, it is unclear whether prior visual experience is necessary to generate these internal representations. Subject EA, an early blind artist, provides insight into this question. Like other blind individuals, EA captures the external world by touch. However, he is also able to reveal his internal representations through highly detailed drawings that are unequivocally understandable by a sighted person. We employed fMRI to investigate the neural correlates associated with EA's ability to transform tactilely explored three-dimensional objects into drawings and contrasted these findings with a series of control conditions (e.g. nonsensical scribbling as a sensory-motor control). Activation during drawing (compared to scribbling) occurred in brain areas normally associated with vision, including the striate cortex along with frontal and parietal cortical regions. Some of these areas showed overlap when EA was asked to mentally imagine the pictures he had to draw (albeit to a lesser anatomical extent and signal magnitude). These results have important implications as regards our understanding of the ways in which tactile information can generate mental representations of shapes and scenes in the absence of normal visual development. Furthermore, these findings suggest the occipital cortex plays a key role in supporting mental representations even without prior visual experience.</div>
</front>
</TEI>
<affiliations><list><country><li>Allemagne</li>
<li>Israël</li>
<li>États-Unis</li>
</country>
<region><li>Berlin</li>
<li>Massachusetts</li>
</region>
<settlement><li>Berlin</li>
</settlement>
</list>
<tree><country name="États-Unis"><region name="Massachusetts"><name sortKey="Amedi, Amir" sort="Amedi, Amir" uniqKey="Amedi A" first="Amir" last="Amedi">Amir Amedi</name>
</region>
<name sortKey="Bermpohl, Felix" sort="Bermpohl, Felix" uniqKey="Bermpohl F" first="Felix" last="Bermpohl">Felix Bermpohl</name>
<name sortKey="Camprodon, Joan" sort="Camprodon, Joan" uniqKey="Camprodon J" first="Joan" last="Camprodon">Joan Camprodon</name>
<name sortKey="Fox, Sharon" sort="Fox, Sharon" uniqKey="Fox S" first="Sharon" last="Fox">Sharon Fox</name>
<name sortKey="Kim, Dae Shik" sort="Kim, Dae Shik" uniqKey="Kim D" first="Dae-Shik" last="Kim">Dae-Shik Kim</name>
<name sortKey="Merabet, Lotfi B" sort="Merabet, Lotfi B" uniqKey="Merabet L" first="Lotfi B." last="Merabet">Lotfi B. Merabet</name>
<name sortKey="Pascual Leone, Alvaro" sort="Pascual Leone, Alvaro" uniqKey="Pascual Leone A" first="Alvaro" last="Pascual-Leone">Alvaro Pascual-Leone</name>
<name sortKey="Ronen, Itamar" sort="Ronen, Itamar" uniqKey="Ronen I" first="Itamar" last="Ronen">Itamar Ronen</name>
</country>
<country name="Israël"><noRegion><name sortKey="Amedi, Amir" sort="Amedi, Amir" uniqKey="Amedi A" first="Amir" last="Amedi">Amir Amedi</name>
</noRegion>
</country>
<country name="Allemagne"><region name="Berlin"><name sortKey="Bermpohl, Felix" sort="Bermpohl, Felix" uniqKey="Bermpohl F" first="Felix" last="Bermpohl">Felix Bermpohl</name>
</region>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/HapticV1/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 005325 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 005325 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Ticri/CIDE |area= HapticV1 |flux= Main |étape= Merge |type= RBID |clé= Pascal:09-0115567 |texte= Neural and behavioral correlates of drawing in an early blind painter : A case study }}
![]() | This area was generated with Dilib version V0.6.23. | ![]() |