HapticV1, Main, Merge, bibRecord, 002274

Pilot Study for OCT Guided Design and Fit of a Prosthetic Device for Treatment of Corneal Disease

Identifieur interne : 002274 ( Main/Merge ); précédent : 002273; suivant : 002275

Pilot Study for OCT Guided Design and Fit of a Prosthetic Device for Treatment of Corneal Disease

Auteurs : Hong-Gam T. Le [États-Unis] ; Maolong Tang [États-Unis] ; Ryan Ridges [États-Unis] ; David Huang [États-Unis] ; Deborah S. Jacobs [États-Unis]

Source :

Journal of Ophthalmology [ 2090-004X ] ; 2012.

RBID : PMC:3536438

Abstract

Purpose. To assess optical coherence tomography (OCT) for guiding design and fit of a prosthetic device for corneal disease. Methods. A prototype time domain OCT scanner was used to image the anterior segment of patients fitted with large diameter (18.5–20 mm) prosthetic devices for corneal disease. OCT images were processed and analyzed to characterize corneal diameter, corneal sagittal height, scleral sagittal height, scleral toricity, and alignment of device. Within-subject variance of OCT-measured parameters was evaluated. OCT-measured parameters were compared with device parameters for each eye fitted. OCT image correspondence with ocular alignment and clinical fit was assessed. Results. Six eyes in 5 patients were studied. OCT measurement of corneal diameter (coefficient of variation, CV = 0.76%), cornea sagittal height (CV = 2.06%), and scleral sagittal height (CV = 3.39%) is highly repeatable within each subject. OCT image-derived measurements reveal strong correlation between corneal sagittal height and device corneal height (r = 0.975) and modest correlation between scleral and on-eye device toricity (r = 0.581). Qualitative assessment of a fitted device on OCT montages reveals correspondence with slit lamp images and clinical assessment of fit. Conclusions. OCT imaging of the anterior segment is suitable for custom design and fit of large diameter (18.5–20 mm) prosthetic devices used in the treatment of corneal disease.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3536438

DOI: 10.1155/2012/812034
PubMed: 23316338
PubMed Central: 3536438

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PMC:3536438

Le document en format XML

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<author><name sortKey="Le, Hong Gam T" sort="Le, Hong Gam T" uniqKey="Le H" first="Hong-Gam T." last="Le">Hong-Gam T. Le</name>
<affiliation wicri:level="2"><nlm:aff id="I1">Boston Foundation for Sight, 464 Hillside Avenue, Suite 205, Needham, MA 02494, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
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<author><name sortKey="Tang, Maolong" sort="Tang, Maolong" uniqKey="Tang M" first="Maolong" last="Tang">Maolong Tang</name>
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<affiliation wicri:level="2"><nlm:aff id="I3">Department of Ophthalmology, Harvard Medical School, Boston, MA, USA</nlm:aff>
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<author><name sortKey="Le, Hong Gam T" sort="Le, Hong Gam T" uniqKey="Le H" first="Hong-Gam T." last="Le">Hong-Gam T. Le</name>
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<author><name sortKey="Tang, Maolong" sort="Tang, Maolong" uniqKey="Tang M" first="Maolong" last="Tang">Maolong Tang</name>
<affiliation wicri:level="2"><nlm:aff id="I2">Center for Ophthalmic Optics and Lasers, Casey Eye Institute, Oregon University of Health & Science, Portland, OR, USA</nlm:aff>
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<author><name sortKey="Ridges, Ryan" sort="Ridges, Ryan" uniqKey="Ridges R" first="Ryan" last="Ridges">Ryan Ridges</name>
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<author><name sortKey="Huang, David" sort="Huang, David" uniqKey="Huang D" first="David" last="Huang">David Huang</name>
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<author><name sortKey="Jacobs, Deborah S" sort="Jacobs, Deborah S" uniqKey="Jacobs D" first="Deborah S." last="Jacobs">Deborah S. Jacobs</name>
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<series><title level="j">Journal of Ophthalmology</title>
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<front><div type="abstract" xml:lang="en"><p><italic>Purpose</italic>
. To assess optical coherence tomography (OCT) for guiding design and fit of a prosthetic device for corneal disease. <italic>Methods</italic>
. A prototype time domain OCT scanner was used to image the anterior segment of patients fitted with large diameter (18.5–20 mm) prosthetic devices for corneal disease. OCT images were processed and analyzed to characterize corneal diameter, corneal sagittal height, scleral sagittal height, scleral toricity, and alignment of device. Within-subject variance of OCT-measured parameters was evaluated. OCT-measured parameters were compared with device parameters for each eye fitted. OCT image correspondence with ocular alignment and clinical fit was assessed. <italic>Results</italic>
. Six eyes in 5 patients were studied. OCT measurement of corneal diameter (coefficient of variation, CV = 0.76%), cornea sagittal height (CV = 2.06%), and scleral sagittal height (CV = 3.39%) is highly repeatable within each subject. OCT image-derived measurements reveal strong correlation between corneal sagittal height and device corneal height (<italic>r</italic>
 = 0.975) and modest correlation between scleral and on-eye device toricity (<italic>r</italic>
 = 0.581). Qualitative assessment of a fitted device on OCT montages reveals correspondence with slit lamp images and clinical assessment of fit. <italic>Conclusions</italic>
. OCT imaging of the anterior segment is suitable for custom design and fit of large diameter (18.5–20 mm) prosthetic devices used in the treatment of corneal disease.</p>
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<author><name sortKey="Rosenthal, P" uniqKey="Rosenthal P">P Rosenthal</name>
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<biblStruct><analytic><author><name sortKey="Romero Rangel, T" uniqKey="Romero Rangel T">T Romero-Rangel</name>
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Pilot Study for OCT Guided Design and Fit of a Prosthetic Device for Treatment of Corneal Disease

Pilot Study for OCT Guided Design and Fit of a Prosthetic Device for Treatment of Corneal Disease

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Abstract

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