Is DOPA-Responsive Hypokinesia Responsible for Bimanual Coordination Deficits in Parkinson’s Disease?
Identifieur interne : 001A86 ( Main/Merge ); précédent : 001A85; suivant : 001A87Is DOPA-Responsive Hypokinesia Responsible for Bimanual Coordination Deficits in Parkinson’s Disease?
Auteurs : Quincy J. Almeida [Canada] ; Matt J. N. Brown [Canada]Source :
- Frontiers in Neurology [ 1664-2295 ] ; 2013.
Abstract
Bradykinesia is a well-documented DOPA-responsive clinical feature of Parkinson’s disease (PD). While amplitude deficits (hypokinesia) are a key component of this slowness, it is important to consider how dopamine influences both the amplitude (hypokinesia) and frequency components of bradykinesia when a bimanually coordinated movement is required. Based on the notion that the basal ganglia are associated with sensory deficits, the influence of dopaminergic replacement on sensory feedback conditions during bimanual coordination was also evaluated. Bimanual movements were examined in PD and healthy comparisons in an unconstrained three-dimensional coordination task. PD were tested “off” (overnight withdrawal of dopaminergic treatment) and “on” (peak dose of dopaminergic treatment), while the healthy group was evaluated for practice effects across two sessions. Required cycle frequency (increased within each trial from 0.75 to 2 Hz), type of visual feedback (
Url:
DOI: 10.3389/fneur.2013.00089
PubMed: 23882254
PubMed Central: 3715734
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 001E27
- to stream Pmc, to step Curation: 001E27
- to stream Pmc, to step Checkpoint: 001179
- to stream Ncbi, to step Merge: 002822
- to stream Ncbi, to step Curation: 002822
- to stream Ncbi, to step Checkpoint: 002822
Links to Exploration step
PMC:3715734Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Is DOPA-Responsive Hypokinesia Responsible for Bimanual Coordination Deficits in Parkinson’s Disease?</title><author><name sortKey="Almeida, Quincy J" sort="Almeida, Quincy J" uniqKey="Almeida Q" first="Quincy J." last="Almeida">Quincy J. Almeida</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Sun Life Financial Movement Disorders Research and Rehabilitation Centre (MDRC), Wilfrid Laurier University</institution>,<addr-line>Waterloo, ON</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Brown, Matt J N" sort="Brown, Matt J N" uniqKey="Brown M" first="Matt J. N." last="Brown">Matt J. N. Brown</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Sun Life Financial Movement Disorders Research and Rehabilitation Centre (MDRC), Wilfrid Laurier University</institution>,<addr-line>Waterloo, ON</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23882254</idno><idno type="pmc">3715734</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3715734</idno><idno type="RBID">PMC:3715734</idno><idno type="doi">10.3389/fneur.2013.00089</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">001E27</idno><idno type="wicri:Area/Pmc/Curation">001E27</idno><idno type="wicri:Area/Pmc/Checkpoint">001179</idno><idno type="wicri:Area/Ncbi/Merge">002822</idno><idno type="wicri:Area/Ncbi/Curation">002822</idno><idno type="wicri:Area/Ncbi/Checkpoint">002822</idno><idno type="wicri:Area/Main/Merge">001A86</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Is DOPA-Responsive Hypokinesia Responsible for Bimanual Coordination Deficits in Parkinson’s Disease?</title><author><name sortKey="Almeida, Quincy J" sort="Almeida, Quincy J" uniqKey="Almeida Q" first="Quincy J." last="Almeida">Quincy J. Almeida</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Sun Life Financial Movement Disorders Research and Rehabilitation Centre (MDRC), Wilfrid Laurier University</institution>,<addr-line>Waterloo, ON</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Brown, Matt J N" sort="Brown, Matt J N" uniqKey="Brown M" first="Matt J. N." last="Brown">Matt J. N. Brown</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>Sun Life Financial Movement Disorders Research and Rehabilitation Centre (MDRC), Wilfrid Laurier University</institution>,<addr-line>Waterloo, ON</addr-line>,<country>Canada</country></nlm:aff><country xml:lang="fr">Canada</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Frontiers in Neurology</title><idno type="eISSN">1664-2295</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Bradykinesia is a well-documented DOPA-responsive clinical feature of Parkinson’s disease (PD). While amplitude deficits (hypokinesia) are a key component of this slowness, it is important to consider how dopamine influences both the amplitude (hypokinesia) and frequency components of bradykinesia when a bimanually coordinated movement is required. Based on the notion that the basal ganglia are associated with sensory deficits, the influence of dopaminergic replacement on sensory feedback conditions during bimanual coordination was also evaluated. Bimanual movements were examined in PD and healthy comparisons in an unconstrained three-dimensional coordination task. PD were tested “off” (overnight withdrawal of dopaminergic treatment) and “on” (peak dose of dopaminergic treatment), while the healthy group was evaluated for practice effects across two sessions. Required cycle frequency (increased within each trial from 0.75 to 2 Hz), type of visual feedback (<italic>no vision</italic>, <italic>normal vision</italic>, and <italic>augmented vision)</italic>, and coordination pattern (symmetrical in-phase and non-symmetrical anti-phase) were all manipulated. Overall, coordination (mean accuracy and standard deviation of relative phase) and amplitude deficits during bimanual coordination were confirmed in PD participants. In addition, significant correlations were identified between severity of motor symptoms as well as bradykinesia to greater coordination deficits (accuracy and stability) in PD “off” group. However, even though amplitude deficits (hypokinesia) improved with dopaminergic replacement, it did not improve bimanual coordination performance (accuracy or stability) in PD patients from “off” to “on.” Interestingly, while coordination performance in both groups suffered in the <italic>augmented vision</italic> condition, the amplitude of the more affected limb of PD was notably influenced. It can be concluded that DOPA-responsive hypokinesia contributes to, but is not directly responsible for bimanual coordination impairments in PD. It is likely that bimanual coordination deficits in PD are caused by the combination of dopaminergic system dysfunction as well as other neural impairments that may be DOPA-resistant or related to non-dopaminergic pathways.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Gibb, Wrg" uniqKey="Gibb W">WRG Gibb</name></author><author><name sortKey="Lees, Aj" uniqKey="Lees A">AJ Lees</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lees, Aj" uniqKey="Lees A">AJ Lees</name></author><author><name sortKey="Hardy, J" uniqKey="Hardy J">J Hardy</name></author><author><name sortKey="Revesz, T" uniqKey="Revesz T">T Revesz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Espay, Aj" uniqKey="Espay A">AJ Espay</name></author><author><name sortKey="Beaton, De" uniqKey="Beaton D">DE Beaton</name></author><author><name sortKey="Morgante, F" uniqKey="Morgante F">F Morgante</name></author><author><name sortKey="Gunraj, Ca" uniqKey="Gunraj C">CA Gunraj</name></author><author><name sortKey="Lang, Ae" uniqKey="Lang A">AE Lang</name></author><author><name sortKey="Chen, R" uniqKey="Chen R">R Chen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Morris, Me" uniqKey="Morris M">ME Morris</name></author><author><name sortKey="Iansek, R" uniqKey="Iansek R">R Iansek</name></author><author><name sortKey="Matyas, Ta" uniqKey="Matyas T">TA Matyas</name></author><author><name sortKey="Summers, Jj" uniqKey="Summers J">JJ Summers</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Almeida, Qj" uniqKey="Almeida Q">QJ Almeida</name></author><author><name sortKey="Wishart, Lr" uniqKey="Wishart L">LR Wishart</name></author><author><name sortKey="Lee, Td" uniqKey="Lee T">TD Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Serrien, Dj" uniqKey="Serrien D">DJ Serrien</name></author><author><name sortKey="Steyvers, M" uniqKey="Steyvers M">M Steyvers</name></author><author><name sortKey="Debaere, F" uniqKey="Debaere F">F Debaere</name></author><author><name sortKey="Stelmach, Ge" uniqKey="Stelmach G">GE Stelmach</name></author><author><name sortKey="Swinnen, Sp" uniqKey="Swinnen S">SP Swinnen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Byblow, Wd" uniqKey="Byblow W">WD Byblow</name></author><author><name sortKey="Summers, Jj" uniqKey="Summers J">JJ Summers</name></author><author><name sortKey="Thomas, J" uniqKey="Thomas J">J Thomas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Van Den Berg, C" uniqKey="Van Den Berg C">C van den Berg</name></author><author><name sortKey="Beek, Pj" uniqKey="Beek P">PJ Beek</name></author><author><name sortKey="Wagenaar, Rc" uniqKey="Wagenaar R">RC Wagenaar</name></author><author><name sortKey="Van Wieringen, Pcw" uniqKey="Van Wieringen P">PCW Van Wieringen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Almeida, Qj" uniqKey="Almeida Q">QJ Almeida</name></author><author><name sortKey="Frank, Js" uniqKey="Frank J">JS Frank</name></author><author><name sortKey="Roy, Ea" uniqKey="Roy E">EA Roy</name></author><author><name sortKey="Patla, Ae" uniqKey="Patla A">AE Patla</name></author><author><name sortKey="Jog, Ms" uniqKey="Jog M">MS Jog</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Swinnen, Sp" uniqKey="Swinnen S">SP Swinnen</name></author><author><name sortKey="Van Langendonk, L" uniqKey="Van Langendonk L">L Van Langendonk</name></author><author><name sortKey="Verschueren, S" uniqKey="Verschueren S">S Verschueren</name></author><author><name sortKey="Peeters, G" uniqKey="Peeters G">G Peeters</name></author><author><name sortKey="Dom, R" uniqKey="Dom R">R Dom</name></author><author><name sortKey="De Weerdt, W" uniqKey="De Weerdt W">W De Weerdt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Byblow, Wd" uniqKey="Byblow W">WD Byblow</name></author><author><name sortKey="Summers, Jj" uniqKey="Summers J">JJ Summers</name></author><author><name sortKey="Lewis, Gn" uniqKey="Lewis G">GN Lewis</name></author><author><name sortKey="Thomas, J" uniqKey="Thomas J">J Thomas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brown, Mjn" uniqKey="Brown M">MJN Brown</name></author><author><name sortKey="Almeida, Qj" uniqKey="Almeida Q">QJ Almeida</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Berardelli, A" uniqKey="Berardelli A">A Berardelli</name></author><author><name sortKey="Rothwell, Jc" uniqKey="Rothwell J">JC Rothwell</name></author><author><name sortKey="Thompson, Pd" uniqKey="Thompson P">PD Thompson</name></author><author><name sortKey="Hallett, M" uniqKey="Hallett M">M Hallett</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Oullier, O" uniqKey="Oullier O">O Oullier</name></author><author><name sortKey="Jantzen, Kj" uniqKey="Jantzen K">KJ Jantzen</name></author><author><name sortKey="Steinberg, Fl" uniqKey="Steinberg F">FL Steinberg</name></author><author><name sortKey="Kelso, Jas" uniqKey="Kelso J">JAS Kelso</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Swinnen, Sp" uniqKey="Swinnen S">SP Swinnen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Carson, Rg" uniqKey="Carson R">RG Carson</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Aramaki, Y" uniqKey="Aramaki Y">Y Aramaki</name></author><author><name sortKey="Honda, M" uniqKey="Honda M">M Honda</name></author><author><name sortKey="Okada, T" uniqKey="Okada T">T Okada</name></author><author><name sortKey="Sadato, N" uniqKey="Sadato N">N Sadato</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="De Luca, C" uniqKey="De Luca C">C De Luca</name></author><author><name sortKey="Jantzen, Kj" uniqKey="Jantzen K">KJ Jantzen</name></author><author><name sortKey="Comani, S" uniqKey="Comani S">S Comani</name></author><author><name sortKey="Bertollo, M" uniqKey="Bertollo M">M Bertollo</name></author><author><name sortKey="Kelso, Jas" uniqKey="Kelso J">JAS Kelso</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Lim, Vk" uniqKey="Lim V">VK Lim</name></author><author><name sortKey="Hamm, Jp" uniqKey="Hamm J">JP Hamm</name></author><author><name sortKey="Byblow, Wd" uniqKey="Byblow W">WD Byblow</name></author><author><name sortKey="Kirk, Ij" uniqKey="Kirk I">IJ Kirk</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Abbruzzese, G" uniqKey="Abbruzzese G">G Abbruzzese</name></author><author><name sortKey="Berardelli, A" uniqKey="Berardelli A">A Berardelli</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schettino, Lf" uniqKey="Schettino L">LF Schettino</name></author><author><name sortKey="Adamovich, Sv" uniqKey="Adamovich S">SV Adamovich</name></author><author><name sortKey="Hening, W" uniqKey="Hening W">W Hening</name></author><author><name sortKey="Tunik, E" uniqKey="Tunik E">E Tunik</name></author><author><name sortKey="Sage, J" uniqKey="Sage J">J Sage</name></author><author><name sortKey="Poizner, H" uniqKey="Poizner H">H Poizner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Almeida, Qj" uniqKey="Almeida Q">QJ Almeida</name></author><author><name sortKey="Wishart, Lr" uniqKey="Wishart L">LR Wishart</name></author><author><name sortKey="Lee, Td" uniqKey="Lee T">TD Lee</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ridderikhoff, A" uniqKey="Ridderikhoff A">A Ridderikhoff</name></author><author><name sortKey="Peper, Cle" uniqKey="Peper C">CLE Peper</name></author><author><name sortKey="Beek, Pj" uniqKey="Beek P">PJ Beek</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Johnson, Ka" uniqKey="Johnson K">KA Johnson</name></author><author><name sortKey="Cunnington, R" uniqKey="Cunnington R">R Cunnington</name></author><author><name sortKey="Bradshaw, Jl" uniqKey="Bradshaw J">JL Bradshaw</name></author><author><name sortKey="Phillips, Jg" uniqKey="Phillips J">JG Phillips</name></author><author><name sortKey="Iansek, R" uniqKey="Iansek R">R Iansek</name></author><author><name sortKey="Rogers, Ma" uniqKey="Rogers M">MA Rogers</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Brown, R" uniqKey="Brown R">R Brown</name></author><author><name sortKey="Jahanshahi, M" uniqKey="Jahanshahi M">M Jahanshahi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Horstink, Mw" uniqKey="Horstink M">MW Horstink</name></author><author><name sortKey="Berger, Hj" uniqKey="Berger H">HJ Berger</name></author><author><name sortKey="Van Spaendonck, Kp" uniqKey="Van Spaendonck K">KP Van Spaendonck</name></author><author><name sortKey="Van Den Bercken, Jh" uniqKey="Van Den Bercken J">JH Van den Bercken</name></author><author><name sortKey="Cools, Ar" uniqKey="Cools A">AR Cools</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rodriguez Oroz, Mc" uniqKey="Rodriguez Oroz M">MC Rodriguez-Oroz</name></author><author><name sortKey="Jahanshahi, M" uniqKey="Jahanshahi M">M Jahanshahi</name></author><author><name sortKey="Krack, P" uniqKey="Krack P">P Krack</name></author><author><name sortKey="Litvan, I" uniqKey="Litvan I">I Litvan</name></author><author><name sortKey="Macias, R" uniqKey="Macias R">R Macias</name></author><author><name sortKey="Bezard, E" uniqKey="Bezard E">E Bezard</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rodriguez Oroz, Mc" uniqKey="Rodriguez Oroz M">MC Rodriguez-Oroz</name></author><author><name sortKey="Lage, Pm" uniqKey="Lage P">PM Lage</name></author><author><name sortKey="Sanchez Mut, J" uniqKey="Sanchez Mut J">J Sanchez-Mut</name></author><author><name sortKey="Lamet, I" uniqKey="Lamet I">I Lamet</name></author><author><name sortKey="Pagonabarraga, J" uniqKey="Pagonabarraga J">J Pagonabarraga</name></author><author><name sortKey="Toledo, Jb" uniqKey="Toledo J">JB Toledo</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Leroi, I" uniqKey="Leroi I">I Leroi</name></author><author><name sortKey="Collins, D" uniqKey="Collins D">D Collins</name></author><author><name sortKey="Marsh, L" uniqKey="Marsh L">L Marsh</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Riekkinen, M" uniqKey="Riekkinen M">M Riekkinen</name></author><author><name sortKey="Kejonen, K" uniqKey="Kejonen K">K Kejonen</name></author><author><name sortKey="Jakala, P" uniqKey="Jakala P">P Jakala</name></author><author><name sortKey="Soininen, H" uniqKey="Soininen H">H Soininen</name></author><author><name sortKey="Riekkinen, P" uniqKey="Riekkinen P">P Riekkinen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Steenhuis, R" uniqKey="Steenhuis R">R Steenhuis</name></author><author><name sortKey="Bryden, M" uniqKey="Bryden M">M Bryden</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Teng, E" uniqKey="Teng E">E Teng</name></author><author><name sortKey="Chui, H" uniqKey="Chui H">H Chui</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tombaugh, T" uniqKey="Tombaugh T">T Tombaugh</name></author><author><name sortKey="Mcdowell, I" uniqKey="Mcdowell I">I McDowell</name></author><author><name sortKey="Kristjansson, B" uniqKey="Kristjansson B">B Kristjansson</name></author><author><name sortKey="Hubley, A" uniqKey="Hubley A">A Hubley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Fahn, S" uniqKey="Fahn S">S Fahn</name></author><author><name sortKey="Elton, R" uniqKey="Elton R">R Elton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Tomlinson, Cl" uniqKey="Tomlinson C">CL Tomlinson</name></author><author><name sortKey="Stowe, R" uniqKey="Stowe R">R Stowe</name></author><author><name sortKey="Patel, S" uniqKey="Patel S">S Patel</name></author><author><name sortKey="Rick, C" uniqKey="Rick C">C Rick</name></author><author><name sortKey="Gray, R" uniqKey="Gray R">R Gray</name></author><author><name sortKey="Clarke, Ce" uniqKey="Clarke C">CE Clarke</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kishore, A" uniqKey="Kishore A">A Kishore</name></author><author><name sortKey="Espay, Aj" uniqKey="Espay A">AJ Espay</name></author><author><name sortKey="Marras, C" uniqKey="Marras C">C Marras</name></author><author><name sortKey="Al Khairalla, T" uniqKey="Al Khairalla T">T Al-Khairalla</name></author><author><name sortKey="Arenovich, T" uniqKey="Arenovich T">T Arenovich</name></author><author><name sortKey="Asante, A" uniqKey="Asante A">A Asante</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Plotnik, M" uniqKey="Plotnik M">M Plotnik</name></author><author><name sortKey="Giladi, N" uniqKey="Giladi N">N Giladi</name></author><author><name sortKey="Balash, Y" uniqKey="Balash Y">Y Balash</name></author><author><name sortKey="Peretz, C" uniqKey="Peretz C">C Peretz</name></author><author><name sortKey="Hausdorff, Jm" uniqKey="Hausdorff J">JM Hausdorff</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Plotnik, M" uniqKey="Plotnik M">M Plotnik</name></author><author><name sortKey="Giladi, N" uniqKey="Giladi N">N Giladi</name></author><author><name sortKey="Hausdorff, Jm" uniqKey="Hausdorff J">JM Hausdorff</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Haken, H" uniqKey="Haken H">H Haken</name></author><author><name sortKey="Kelso, Jas" uniqKey="Kelso J">JAS Kelso</name></author><author><name sortKey="Bunz, H" uniqKey="Bunz H">H Bunz</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kelso, Jas" uniqKey="Kelso J">JAS Kelso</name></author><author><name sortKey="Southard, Dl" uniqKey="Southard D">DL Southard</name></author><author><name sortKey="Goodman, D" uniqKey="Goodman D">D Goodman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Kelso, Jas" uniqKey="Kelso J">JAS Kelso</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schoner, G" uniqKey="Schoner G">G Schoner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yamanishi, J" uniqKey="Yamanishi J">J Yamanishi</name></author><author><name sortKey="Kawato, M" uniqKey="Kawato M">M Kawato</name></author><author><name sortKey="Suzuki, R" uniqKey="Suzuki R">R Suzuki</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Schoner, G" uniqKey="Schoner G">G Schoner</name></author><author><name sortKey="Kelso, Jas" uniqKey="Kelso J">JAS Kelso</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Carson, Rg" uniqKey="Carson R">RG Carson</name></author><author><name sortKey="Kelso, Jas" uniqKey="Kelso J">JAS Kelso</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wu, T" uniqKey="Wu T">T Wu</name></author><author><name sortKey="Wang, L" uniqKey="Wang L">L Wang</name></author><author><name sortKey="Hallett, M" uniqKey="Hallett M">M Hallett</name></author><author><name sortKey="Li, K" uniqKey="Li K">K Li</name></author><author><name sortKey="Chan, P" uniqKey="Chan P">P Chan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Ringenbach, Sdr" uniqKey="Ringenbach S">SDR Ringenbach</name></author><author><name sortKey="Van Gemmert, Awa" uniqKey="Van Gemmert A">AWA Van Gemmert</name></author><author><name sortKey="Shill, Ha" uniqKey="Shill H">HA Shill</name></author><author><name sortKey="Stelmach, Ge" uniqKey="Stelmach G">GE Stelmach</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Freeman, Js" uniqKey="Freeman J">JS Freeman</name></author><author><name sortKey="Cody, Fw" uniqKey="Cody F">FW Cody</name></author><author><name sortKey="Schady, W" uniqKey="Schady W">W Schady</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Georgiou, N" uniqKey="Georgiou N">N Georgiou</name></author><author><name sortKey="Iansek, R" uniqKey="Iansek R">R Iansek</name></author><author><name sortKey="Bradshaw, Jl" uniqKey="Bradshaw J">JL Bradshaw</name></author><author><name sortKey="Phillips, Jg" uniqKey="Phillips J">JG Phillips</name></author><author><name sortKey="Mattingley, Jb" uniqKey="Mattingley J">JB Mattingley</name></author><author><name sortKey="Bradshaw, Ja" uniqKey="Bradshaw J">JA Bradshaw</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Cunnington, R" uniqKey="Cunnington R">R Cunnington</name></author><author><name sortKey="Iansek, R" uniqKey="Iansek R">R Iansek</name></author><author><name sortKey="Bradshaw, Jl" uniqKey="Bradshaw J">JL Bradshaw</name></author><author><name sortKey="Phillips, Jg" uniqKey="Phillips J">JG Phillips</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yahalom, G" uniqKey="Yahalom G">G Yahalom</name></author><author><name sortKey="Simon, Es" uniqKey="Simon E">ES Simon</name></author><author><name sortKey="Thorne, R" uniqKey="Thorne R">R Thorne</name></author><author><name sortKey="Peretz, C" uniqKey="Peretz C">C Peretz</name></author><author><name sortKey="Giladi, N" uniqKey="Giladi N">N Giladi</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Freund, H" uniqKey="Freund H">H Freund</name></author><author><name sortKey="Btidingen, Hj" uniqKey="Btidingen H">HJ Btidingen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Pfann, Kd" uniqKey="Pfann K">KD Pfann</name></author><author><name sortKey="Hoffman, Ds" uniqKey="Hoffman D">DS Hoffman</name></author><author><name sortKey="Gottlieb, Gl" uniqKey="Gottlieb G">GL Gottlieb</name></author><author><name sortKey="Strick, Pl" uniqKey="Strick P">PL Strick</name></author><author><name sortKey="Corcos, Dm" uniqKey="Corcos D">DM Corcos</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Swinnen, Sp" uniqKey="Swinnen S">SP Swinnen</name></author><author><name sortKey="Dounskaia, N" uniqKey="Dounskaia N">N Dounskaia</name></author><author><name sortKey="Levin, O" uniqKey="Levin O">O Levin</name></author><author><name sortKey="Duysens, J" uniqKey="Duysens J">J Duysens</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wenderoth, N" uniqKey="Wenderoth N">N Wenderoth</name></author><author><name sortKey="Debaere, F" uniqKey="Debaere F">F Debaere</name></author><author><name sortKey="Sunaert, S" uniqKey="Sunaert S">S Sunaert</name></author><author><name sortKey="Swinnen, Sp" uniqKey="Swinnen S">SP Swinnen</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Levy Tzedek, S" uniqKey="Levy Tzedek S">S Levy-Tzedek</name></author><author><name sortKey="Krebs, Hi" uniqKey="Krebs H">HI Krebs</name></author><author><name sortKey="Arle, Je" uniqKey="Arle J">JE Arle</name></author><author><name sortKey="Shils, Jl" uniqKey="Shils J">JL Shils</name></author><author><name sortKey="Poizner, H" uniqKey="Poizner H">H Poizner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Wolters, Ec" uniqKey="Wolters E">EC Wolters</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Temprado, J J" uniqKey="Temprado J">J-J Temprado</name></author><author><name sortKey="Zanone, P G" uniqKey="Zanone P">P-G Zanone</name></author><author><name sortKey="Monno, A" uniqKey="Monno A">A Monno</name></author><author><name sortKey="Laurent, M" uniqKey="Laurent M">M Laurent</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mongeon, D" uniqKey="Mongeon D">D Mongeon</name></author><author><name sortKey="Blanchet, P" uniqKey="Blanchet P">P Blanchet</name></author><author><name sortKey="Messier, J" uniqKey="Messier J">J Messier</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Verschueren, Smp" uniqKey="Verschueren S">SMP Verschueren</name></author><author><name sortKey="Swinnen, Sp" uniqKey="Swinnen S">SP Swinnen</name></author><author><name sortKey="Dom, R" uniqKey="Dom R">R Dom</name></author><author><name sortKey="De Weerdt, W" uniqKey="De Weerdt W">W De Weerdt</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Klockgether, T" uniqKey="Klockgether T">T Klockgether</name></author><author><name sortKey="Dichgans, J" uniqKey="Dichgans J">J Dichgans</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Messier, J" uniqKey="Messier J">J Messier</name></author><author><name sortKey="Adamovich, S" uniqKey="Adamovich S">S Adamovich</name></author><author><name sortKey="Jack, D" uniqKey="Jack D">D Jack</name></author><author><name sortKey="Hening, W" uniqKey="Hening W">W Hening</name></author><author><name sortKey="Sage, J" uniqKey="Sage J">J Sage</name></author><author><name sortKey="Poizner, H" uniqKey="Poizner H">H Poizner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Inzelberg, R" uniqKey="Inzelberg R">R Inzelberg</name></author><author><name sortKey="Schechtman, E" uniqKey="Schechtman E">E Schechtman</name></author><author><name sortKey="Hocherman, S" uniqKey="Hocherman S">S Hocherman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Jahanshahi, M" uniqKey="Jahanshahi M">M Jahanshahi</name></author><author><name sortKey="Wilkinson, L" uniqKey="Wilkinson L">L Wilkinson</name></author><author><name sortKey="Gahir, H" uniqKey="Gahir H">H Gahir</name></author><author><name sortKey="Dharminda, A" uniqKey="Dharminda A">A Dharminda</name></author><author><name sortKey="Lagnado, Da" uniqKey="Lagnado D">DA Lagnado</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Krebs, Hi" uniqKey="Krebs H">HI Krebs</name></author><author><name sortKey="Hogan, N" uniqKey="Hogan N">N Hogan</name></author><author><name sortKey="Hening, W" uniqKey="Hening W">W Hening</name></author><author><name sortKey="Adamovich, Sv" uniqKey="Adamovich S">SV Adamovich</name></author><author><name sortKey="Poizner, H" uniqKey="Poizner H">H Poizner</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Feigin, A" uniqKey="Feigin A">A Feigin</name></author><author><name sortKey="Ghilardi, Mf" uniqKey="Ghilardi M">MF Ghilardi</name></author><author><name sortKey="Carbon, M" uniqKey="Carbon M">M Carbon</name></author><author><name sortKey="Edwards, C" uniqKey="Edwards C">C Edwards</name></author><author><name sortKey="Fukuda, M" uniqKey="Fukuda M">M Fukuda</name></author><author><name sortKey="Dhawan, V" uniqKey="Dhawan V">V Dhawan</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Corbetta, M" uniqKey="Corbetta M">M Corbetta</name></author><author><name sortKey="Shulman, Gl" uniqKey="Shulman G">GL Shulman</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Knight, Rt" uniqKey="Knight R">RT Knight</name></author><author><name sortKey="Staines, Wr" uniqKey="Staines W">WR Staines</name></author><author><name sortKey="Swick, D" uniqKey="Swick D">D Swick</name></author><author><name sortKey="Chao, Ll" uniqKey="Chao L">LL Chao</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Yarnall, A" uniqKey="Yarnall A">A Yarnall</name></author><author><name sortKey="Rochester, L" uniqKey="Rochester L">L Rochester</name></author><author><name sortKey="Burn, Dj" uniqKey="Burn D">DJ Burn</name></author></analytic></biblStruct></listBibl></div1></back></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/HapticV1/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001A86 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 001A86 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Ticri/CIDE
|area= HapticV1
|flux= Main
|étape= Merge
|type= RBID
|clé= PMC:3715734
|texte= Is DOPA-Responsive Hypokinesia Responsible for Bimanual Coordination Deficits in Parkinson’s Disease?
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Merge/RBID.i -Sk "pubmed:23882254" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Merge/biblio.hfd \
| NlmPubMed2Wicri -a HapticV1
| This area was generated with Dilib version V0.6.23. |  |