Spatial encoding and underlying circutry in scene-selective cortex
Identifieur interne : 001857 ( Main/Merge ); précédent : 001856; suivant : 001858Spatial encoding and underlying circutry in scene-selective cortex
Auteurs : Shahin Nasr [États-Unis] ; Kathryn J. Devaney [États-Unis] ; Roger Bh Tootell [États-Unis]Source :
- NeuroImage [ 1053-8119 ] ; 2013.
Abstract
Three cortical areas (Retro-Splenial Cortex (RSC), Transverse Occipital Sulcus (TOS) and Parahippocampal Place Area (PPA)) respond selectively to scenes. However, their wider role in spatial encoding and their functional connectivity remains unclear. Using fMRI, first we tested the responses of these areas during spatial comparison tasks using dot targets on white noise. Activity increased during task performance in both RSC and TOS, but not in PPA. However, the amplitude of task-driven activity and behavioral measures of task demand were correlated only in RSC. A control experiment showed that none of these areas were activated during a comparable shape comparison task.
Secondly, we analyzed functional connectivity of these areas during the resting state. Results revealed a significant connection between RSC and frontal association areas (known to be involved in perceptual decision-making). In contrast, TOS showed functional connections dorsally with the Inferior Parietal Sulcus, and ventrally with the Lateral Occipital Complex - but not with RSC and/or frontal association areas. Moreover, RSC and TOS showed differentiable functional connections with the anterior-medial and posterior-lateral parts of PPA, respectively. These results suggest two parallel pathways for spatial encoding, including RSC and TOS respectively. Only the RSC network was involved in active spatial comparisons.
Url:
DOI: 10.1016/j.neuroimage.2013.07.030
PubMed: 23872156
PubMed Central: 3815999
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 001A92
- to stream Pmc, to step Curation: 001A92
- to stream Pmc, to step Checkpoint: 001004
- to stream Ncbi, to step Merge: 002813
- to stream Ncbi, to step Curation: 002813
- to stream Ncbi, to step Checkpoint: 002813
Links to Exploration step
PMC:3815999Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Spatial encoding and underlying circutry in scene-selective cortex</title><author><name sortKey="Nasr, Shahin" sort="Nasr, Shahin" uniqKey="Nasr S" first="Shahin" last="Nasr">Shahin Nasr</name><affiliation wicri:level="2"><nlm:aff id="A1">Martinos Center for Biomedical Imaging, Massachusetts General Hospital, 149 13<sup>th</sup> St., Charlestown, MA 02129</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea> St., Charlestown</wicri:cityArea></affiliation></author><author><name sortKey="Devaney, Kathryn J" sort="Devaney, Kathryn J" uniqKey="Devaney K" first="Kathryn J." last="Devaney">Kathryn J. Devaney</name><affiliation wicri:level="2"><nlm:aff id="A1">Martinos Center for Biomedical Imaging, Massachusetts General Hospital, 149 13<sup>th</sup> St., Charlestown, MA 02129</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea> St., Charlestown</wicri:cityArea></affiliation></author><author><name sortKey="Tootell, Roger Bh" sort="Tootell, Roger Bh" uniqKey="Tootell R" first="Roger Bh" last="Tootell">Roger Bh Tootell</name><affiliation wicri:level="2"><nlm:aff id="A1">Martinos Center for Biomedical Imaging, Massachusetts General Hospital, 149 13<sup>th</sup> St., Charlestown, MA 02129</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea> St., Charlestown</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A2">National Institute of Mental Health, Laboratory of Brain and Cognition, 49 Convent Drive, Building 49, Bethesda, MD 20892</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>National Institute of Mental Health, Laboratory of Brain and Cognition, 49 Convent Drive, Building 49, Bethesda</wicri:cityArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23872156</idno><idno type="pmc">3815999</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3815999</idno><idno type="RBID">PMC:3815999</idno><idno type="doi">10.1016/j.neuroimage.2013.07.030</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">001A92</idno><idno type="wicri:Area/Pmc/Curation">001A92</idno><idno type="wicri:Area/Pmc/Checkpoint">001004</idno><idno type="wicri:Area/Ncbi/Merge">002813</idno><idno type="wicri:Area/Ncbi/Curation">002813</idno><idno type="wicri:Area/Ncbi/Checkpoint">002813</idno><idno type="wicri:doubleKey">1053-8119:2013:Nasr S:spatial:encoding:and</idno><idno type="wicri:Area/Main/Merge">001857</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Spatial encoding and underlying circutry in scene-selective cortex</title><author><name sortKey="Nasr, Shahin" sort="Nasr, Shahin" uniqKey="Nasr S" first="Shahin" last="Nasr">Shahin Nasr</name><affiliation wicri:level="2"><nlm:aff id="A1">Martinos Center for Biomedical Imaging, Massachusetts General Hospital, 149 13<sup>th</sup> St., Charlestown, MA 02129</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea> St., Charlestown</wicri:cityArea></affiliation></author><author><name sortKey="Devaney, Kathryn J" sort="Devaney, Kathryn J" uniqKey="Devaney K" first="Kathryn J." last="Devaney">Kathryn J. Devaney</name><affiliation wicri:level="2"><nlm:aff id="A1">Martinos Center for Biomedical Imaging, Massachusetts General Hospital, 149 13<sup>th</sup> St., Charlestown, MA 02129</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea> St., Charlestown</wicri:cityArea></affiliation></author><author><name sortKey="Tootell, Roger Bh" sort="Tootell, Roger Bh" uniqKey="Tootell R" first="Roger Bh" last="Tootell">Roger Bh Tootell</name><affiliation wicri:level="2"><nlm:aff id="A1">Martinos Center for Biomedical Imaging, Massachusetts General Hospital, 149 13<sup>th</sup> St., Charlestown, MA 02129</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Massachusetts</region></placeName><wicri:cityArea> St., Charlestown</wicri:cityArea></affiliation><affiliation wicri:level="2"><nlm:aff id="A2">National Institute of Mental Health, Laboratory of Brain and Cognition, 49 Convent Drive, Building 49, Bethesda, MD 20892</nlm:aff><country xml:lang="fr">États-Unis</country><placeName><region type="state">Maryland</region></placeName><wicri:cityArea>National Institute of Mental Health, Laboratory of Brain and Cognition, 49 Convent Drive, Building 49, Bethesda</wicri:cityArea></affiliation></author></analytic><series><title level="j">NeuroImage</title><idno type="ISSN">1053-8119</idno><idno type="eISSN">1095-9572</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P2">Three cortical areas (Retro-Splenial Cortex (RSC), Transverse Occipital Sulcus (TOS) and Parahippocampal Place Area (PPA)) respond selectively to scenes. However, their wider role in spatial encoding and their functional connectivity remains unclear. Using fMRI, first we tested the responses of these areas during spatial comparison tasks using dot targets on white noise. Activity increased during task performance in both RSC and TOS, but not in PPA. However, the amplitude of task-driven activity and behavioral measures of task demand were correlated only in RSC. A control experiment showed that none of these areas were activated during a comparable shape comparison task.</p><p id="P3">Secondly, we analyzed functional connectivity of these areas during the resting state. Results revealed a significant connection between RSC and frontal association areas (known to be involved in perceptual decision-making). In contrast, TOS showed functional connections dorsally with the Inferior Parietal Sulcus, and ventrally with the Lateral Occipital Complex - but not with RSC and/or frontal association areas. Moreover, RSC and TOS showed differentiable functional connections with the anterior-medial and posterior-lateral parts of PPA, respectively. These results suggest two parallel pathways for spatial encoding, including RSC and TOS respectively. Only the RSC network was involved in active spatial comparisons.</p></div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Ticri/CIDE/explor/HapticV1/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001857 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 001857 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Ticri/CIDE
|area= HapticV1
|flux= Main
|étape= Merge
|type= RBID
|clé= PMC:3815999
|texte= Spatial encoding and underlying circutry in scene-selective cortex
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Merge/RBID.i -Sk "pubmed:23872156" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Merge/biblio.hfd \
| NlmPubMed2Wicri -a HapticV1
| This area was generated with Dilib version V0.6.23. |  |