Perinatal Risks and Childhood Premorbid Indicators of Later Psychosis: Next Steps for Early Psychosocial Interventions
Identifieur interne : 000050 ( Main/Merge ); précédent : 000049; suivant : 000051Perinatal Risks and Childhood Premorbid Indicators of Later Psychosis: Next Steps for Early Psychosocial Interventions
Auteurs : Cindy H. Liu ; Matcheri S. Keshavan ; Ed Tronick ; Larry J. SeidmanSource :
- Schizophrenia Bulletin [ 0586-7614 ] ; 2015.
Abstract
Schizophrenia and affective psychoses are debilitating disorders that together affect 2%–3% of the adult population. Approximately 50%–70% of the offspring of parents with schizophrenia manifest a range of observable difficulties including socioemotional, cognitive, neuromotor, speech-language problems, and psychopathology, and roughly 10% will develop psychosis. Despite the voluminous work on premorbid vulnerabilities to psychosis, especially on schizophrenia, the work on premorbid intervention approaches is scarce. While later interventions during the clinical high-risk (CHR) phase of psychosis, characterized primarily by attenuated positive symptoms, are promising, the CHR period is a relatively late phase of developmental derailment. This article reviews and proposes potential targets for psychosocial interventions during the premorbid period, complementing biological interventions described by others in this Special Theme issue. Beginning with pregnancy, parents with psychoses may benefit from enhanced prenatal care, social support, parenting skills, reduction of symptoms, and programs that are family-centered. For children at risk, we propose preemptive early intervention and cognitive remediation. Empirical research is needed to evaluate these interventions for parents and determine whether interventions for parents and children positively influence the developmental course of the offspring.
Url:
DOI: 10.1093/schbul/sbv047
PubMed: 25904724
PubMed Central: 4466191
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Liu</name><affiliation><nlm:aff id="AF0001"><institution>Department of Psychiatry</institution>,<institution>Harvard Medical School</institution>,<institution>Massachusetts Mental Health Center Division of Public Psychiatry</institution>,<institution>Beth Israel Deaconess Medical Center</institution>,<addr-line>Boston</addr-line>,<addr-line>MA</addr-line>;</nlm:aff></affiliation><affiliation><nlm:aff id="AF0002"><institution>Department of Psychology</institution>,<institution>University of Massachusetts</institution>,<addr-line>Boston</addr-line>,<addr-line>MA</addr-line>;</nlm:aff></affiliation></author><author><name sortKey="Keshavan, Matcheri S" sort="Keshavan, Matcheri S" uniqKey="Keshavan M" first="Matcheri S." last="Keshavan">Matcheri S. 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Seidman</name><affiliation><nlm:aff id="AF0001"><institution>Department of Psychiatry</institution>,<institution>Harvard Medical School</institution>,<institution>Massachusetts Mental Health Center Division of Public Psychiatry</institution>,<institution>Beth Israel Deaconess Medical Center</institution>,<addr-line>Boston</addr-line>,<addr-line>MA</addr-line>;</nlm:aff></affiliation><affiliation><nlm:aff id="AF0004"><institution>Department of Psychiatry, Harvard Medical School</institution>,<institution>Massachusetts General Hospital</institution>,<addr-line>Boston</addr-line>,<addr-line>MA</addr-line></nlm:aff></affiliation></author></analytic><series><title level="j">Schizophrenia Bulletin</title><idno type="ISSN">0586-7614</idno><idno type="eISSN">1745-1701</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Schizophrenia and affective psychoses are debilitating disorders that together affect 2%–3% of the adult population. Approximately 50%–70% of the offspring of parents with schizophrenia manifest a range of observable difficulties including socioemotional, cognitive, neuromotor, speech-language problems, and psychopathology, and roughly 10% will develop psychosis. Despite the voluminous work on premorbid vulnerabilities to psychosis, especially on schizophrenia, the work on premorbid intervention approaches is scarce. While later interventions during the clinical high-risk (CHR) phase of psychosis, characterized primarily by attenuated positive symptoms, are promising, the CHR period is a relatively late phase of developmental derailment. This article reviews and proposes potential targets for psychosocial interventions during the premorbid period, complementing biological interventions described by others in this Special Theme issue. Beginning with pregnancy, parents with psychoses may benefit from enhanced prenatal care, social support, parenting skills, reduction of symptoms, and programs that are family-centered. For children at risk, we propose preemptive early intervention and cognitive remediation. Empirical research is needed to evaluate these interventions for parents and determine whether interventions for parents and children positively influence the developmental course of the offspring.</p></div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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