Association of occupational exposure with features of systemic sclerosis.
Identifieur interne : 000101 ( PubMed/Corpus ); précédent : 000100; suivant : 000102Association of occupational exposure with features of systemic sclerosis.
Auteurs : Isabelle Marie ; Jean-François Menard ; Anne-Bénédicte Duval-Modeste ; Pascal Joly ; Stéphane Dominique ; Pierre Bravard ; David Noël ; Jean-François Gehanno ; Michael Bubenheim ; Jacques Benichou ; Hervé LevesqueSource :
- Journal of the American Academy of Dermatology [ 1097-6787 ] ; 2015.
English descriptors
- KwdEn :
- Adult, Aged, Dermatitis, Occupational (etiology), Female, Humans, Male, Middle Aged, Occupational Exposure (adverse effects), Prospective Studies, Scleroderma, Diffuse (chemically induced), Scleroderma, Systemic (chemically induced), Scleroderma, Systemic (diagnosis), Silicon Dioxide (adverse effects), Solvents (adverse effects).
- MESH :
- chemical , adverse effects : Silicon Dioxide, Solvents.
- adverse effects : Occupational Exposure.
- chemically induced : Scleroderma, Diffuse, Scleroderma, Systemic.
- diagnosis : Scleroderma, Systemic.
- etiology : Dermatitis, Occupational.
- Adult, Aged, Female, Humans, Male, Middle Aged, Prospective Studies.
Abstract
Occupational exposure is reported as playing a substantial causative role in systemic sclerosis (SSc).
DOI: 10.1016/j.jaad.2014.11.027
PubMed: 25582539
Links to Exploration step
pubmed:25582539Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Association of occupational exposure with features of systemic sclerosis.</title><author><name sortKey="Marie, Isabelle" sort="Marie, Isabelle" uniqKey="Marie I" first="Isabelle" last="Marie">Isabelle Marie</name><affiliation><nlm:affiliation>Department of Internal Medicine, Centre Hospitalier Universitaire (CHU) Rouen, and Institut National de la Santé et de la Recherche Biomédicale (INSERM) Unit 905, University of Rouen Institut Fédératif Multidisciplinaire sur les Peptides (IFRMP), Institute for Biochemical Research, Rouen, France. Electronic address: isabelle.marie@chu-rouen.fr.</nlm:affiliation></affiliation></author><author><name sortKey="Menard, Jean Francois" sort="Menard, Jean Francois" uniqKey="Menard J" first="Jean-François" last="Menard">Jean-François Menard</name><affiliation><nlm:affiliation>Department of Biostatistics, CHU Rouen, Rouen, France.</nlm:affiliation></affiliation></author><author><name sortKey="Duval Modeste, Anne Benedicte" sort="Duval Modeste, Anne Benedicte" uniqKey="Duval Modeste A" first="Anne-Bénédicte" last="Duval-Modeste">Anne-Bénédicte Duval-Modeste</name><affiliation><nlm:affiliation>Department of Dermatology, CHU Rouen, Rouen, France.</nlm:affiliation></affiliation></author><author><name sortKey="Joly, Pascal" sort="Joly, Pascal" uniqKey="Joly P" first="Pascal" last="Joly">Pascal Joly</name><affiliation><nlm:affiliation>Department of Dermatology, CHU Rouen, Rouen, France.</nlm:affiliation></affiliation></author><author><name sortKey="Dominique, Stephane" sort="Dominique, Stephane" uniqKey="Dominique S" first="Stéphane" last="Dominique">Stéphane Dominique</name><affiliation><nlm:affiliation>Department of Pneumology, CHU Rouen, Rouen, France.</nlm:affiliation></affiliation></author><author><name sortKey="Bravard, Pierre" sort="Bravard, Pierre" uniqKey="Bravard P" first="Pierre" last="Bravard">Pierre Bravard</name><affiliation><nlm:affiliation>Department of Dermatology, CHG Le Havre, Le Havre, France.</nlm:affiliation></affiliation></author><author><name sortKey="Noel, David" sort="Noel, David" uniqKey="Noel D" first="David" last="Noël">David Noël</name><affiliation><nlm:affiliation>Department of Internal Medicine, Centre Hospitalier Général (CHG) Elbeuf, Elbeuf, France.</nlm:affiliation></affiliation></author><author><name sortKey="Gehanno, Jean Francois" sort="Gehanno, Jean Francois" uniqKey="Gehanno J" first="Jean-François" last="Gehanno">Jean-François Gehanno</name><affiliation><nlm:affiliation>Department of Occupational Medicine, CHU Rouen, Rouen, France.</nlm:affiliation></affiliation></author><author><name sortKey="Bubenheim, Michael" sort="Bubenheim, Michael" uniqKey="Bubenheim M" first="Michael" last="Bubenheim">Michael Bubenheim</name><affiliation><nlm:affiliation>Department of Epidemiology, CHU Rouen, Rouen, France.</nlm:affiliation></affiliation></author><author><name sortKey="Benichou, Jacques" sort="Benichou, Jacques" uniqKey="Benichou J" first="Jacques" last="Benichou">Jacques Benichou</name><affiliation><nlm:affiliation>Department of Epidemiology, CHU Rouen, Rouen, France.</nlm:affiliation></affiliation></author><author><name sortKey="Levesque, Herve" sort="Levesque, Herve" uniqKey="Levesque H" first="Hervé" last="Levesque">Hervé Levesque</name><affiliation><nlm:affiliation>Department of Internal Medicine, Centre Hospitalier Universitaire (CHU) Rouen, and Institut National de la Santé et de la Recherche Biomédicale (INSERM) Unit 905, University of Rouen Institut Fédératif Multidisciplinaire sur les Peptides (IFRMP), Institute for Biochemical Research, Rouen, France.</nlm:affiliation></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2015">2015</date><idno type="RBID">pubmed:25582539</idno><idno type="pmid">25582539</idno><idno type="doi">10.1016/j.jaad.2014.11.027</idno><idno type="wicri:Area/PubMed/Corpus">000101</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Association of occupational exposure with features of systemic sclerosis.</title><author><name sortKey="Marie, Isabelle" sort="Marie, Isabelle" uniqKey="Marie I" first="Isabelle" last="Marie">Isabelle Marie</name><affiliation><nlm:affiliation>Department of Internal Medicine, Centre Hospitalier Universitaire (CHU) Rouen, and Institut National de la Santé et de la Recherche Biomédicale (INSERM) Unit 905, University of Rouen Institut Fédératif Multidisciplinaire sur les Peptides (IFRMP), Institute for Biochemical Research, Rouen, France. Electronic address: isabelle.marie@chu-rouen.fr.</nlm:affiliation></affiliation></author><author><name sortKey="Menard, Jean Francois" sort="Menard, Jean Francois" uniqKey="Menard J" first="Jean-François" last="Menard">Jean-François Menard</name><affiliation><nlm:affiliation>Department of Biostatistics, CHU Rouen, Rouen, France.</nlm:affiliation></affiliation></author><author><name sortKey="Duval Modeste, Anne Benedicte" sort="Duval Modeste, Anne Benedicte" uniqKey="Duval Modeste A" first="Anne-Bénédicte" last="Duval-Modeste">Anne-Bénédicte Duval-Modeste</name><affiliation><nlm:affiliation>Department of Dermatology, CHU Rouen, Rouen, France.</nlm:affiliation></affiliation></author><author><name sortKey="Joly, Pascal" sort="Joly, Pascal" uniqKey="Joly P" first="Pascal" last="Joly">Pascal Joly</name><affiliation><nlm:affiliation>Department of Dermatology, CHU Rouen, Rouen, France.</nlm:affiliation></affiliation></author><author><name sortKey="Dominique, Stephane" sort="Dominique, Stephane" uniqKey="Dominique S" first="Stéphane" last="Dominique">Stéphane Dominique</name><affiliation><nlm:affiliation>Department of Pneumology, CHU Rouen, Rouen, France.</nlm:affiliation></affiliation></author><author><name sortKey="Bravard, Pierre" sort="Bravard, Pierre" uniqKey="Bravard P" first="Pierre" last="Bravard">Pierre Bravard</name><affiliation><nlm:affiliation>Department of Dermatology, CHG Le Havre, Le Havre, France.</nlm:affiliation></affiliation></author><author><name sortKey="Noel, David" sort="Noel, David" uniqKey="Noel D" first="David" last="Noël">David Noël</name><affiliation><nlm:affiliation>Department of Internal Medicine, Centre Hospitalier Général (CHG) Elbeuf, Elbeuf, France.</nlm:affiliation></affiliation></author><author><name sortKey="Gehanno, Jean Francois" sort="Gehanno, Jean Francois" uniqKey="Gehanno J" first="Jean-François" last="Gehanno">Jean-François Gehanno</name><affiliation><nlm:affiliation>Department of Occupational Medicine, CHU Rouen, Rouen, France.</nlm:affiliation></affiliation></author><author><name sortKey="Bubenheim, Michael" sort="Bubenheim, Michael" uniqKey="Bubenheim M" first="Michael" last="Bubenheim">Michael Bubenheim</name><affiliation><nlm:affiliation>Department of Epidemiology, CHU Rouen, Rouen, France.</nlm:affiliation></affiliation></author><author><name sortKey="Benichou, Jacques" sort="Benichou, Jacques" uniqKey="Benichou J" first="Jacques" last="Benichou">Jacques Benichou</name><affiliation><nlm:affiliation>Department of Epidemiology, CHU Rouen, Rouen, France.</nlm:affiliation></affiliation></author><author><name sortKey="Levesque, Herve" sort="Levesque, Herve" uniqKey="Levesque H" first="Hervé" last="Levesque">Hervé Levesque</name><affiliation><nlm:affiliation>Department of Internal Medicine, Centre Hospitalier Universitaire (CHU) Rouen, and Institut National de la Santé et de la Recherche Biomédicale (INSERM) Unit 905, University of Rouen Institut Fédératif Multidisciplinaire sur les Peptides (IFRMP), Institute for Biochemical Research, Rouen, France.</nlm:affiliation></affiliation></author></analytic><series><title level="j">Journal of the American Academy of Dermatology</title><idno type="eISSN">1097-6787</idno><imprint><date when="2015" type="published">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Aged</term><term>Dermatitis, Occupational (etiology)</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Occupational Exposure (adverse effects)</term><term>Prospective Studies</term><term>Scleroderma, Diffuse (chemically induced)</term><term>Scleroderma, Systemic (chemically induced)</term><term>Scleroderma, Systemic (diagnosis)</term><term>Silicon Dioxide (adverse effects)</term><term>Solvents (adverse effects)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Silicon Dioxide</term><term>Solvents</term></keywords><keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Occupational Exposure</term></keywords><keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Scleroderma, Diffuse</term><term>Scleroderma, Systemic</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Scleroderma, Systemic</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Dermatitis, Occupational</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Aged</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Prospective Studies</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Occupational exposure is reported as playing a substantial causative role in systemic sclerosis (SSc).</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">25582539</PMID><DateCreated><Year>2015</Year><Month>2</Month><Day>17</Day></DateCreated><DateCompleted><Year>2015</Year><Month>04</Month><Day>20</Day></DateCompleted><DateRevised><Year>2015</Year><Month>2</Month><Day>17</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1097-6787</ISSN><JournalIssue CitedMedium="Internet"><Volume>72</Volume><Issue>3</Issue><PubDate><Year>2015</Year><Month>Mar</Month></PubDate></JournalIssue><Title>Journal of the American Academy of Dermatology</Title><ISOAbbreviation>J. Am. Acad. Dermatol.</ISOAbbreviation></Journal><ArticleTitle>Association of occupational exposure with features of systemic sclerosis.</ArticleTitle><Pagination><MedlinePgn>456-64</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1016/j.jaad.2014.11.027</ELocationID><ELocationID EIdType="pii" ValidYN="Y">S0190-9622(14)02212-9</ELocationID><Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Occupational exposure is reported as playing a substantial causative role in systemic sclerosis (SSc).</AbstractText><AbstractText Label="OBJECTIVE" NlmCategory="OBJECTIVE">We sought to compare the characteristics of SSc in patients with and without occupational exposure to crystalline silica/solvents.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">In all, 142 patients with SSc were enrolled in this prospective study. An expert committee performed blind evaluation of occupational exposure to crystalline silica/solvents.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Patients exposed to crystalline silica more often exhibited: diffuse cutaneous SSc (P = .02), digital ulcers (P = .05), interstitial lung disease (P = .0004), myocardial dysfunction (P = .006), and cancer (P = .06). Patients exposed to solvents more frequently developed: diffuse cutaneous SSc (P = .001), digital ulcers (P = .01), interstitial lung disease (P = .02), myocardial dysfunction (P = .04), and cancer (P = .003); in addition, these patients were more frequently anti-Scl 70 positive and anticentromere negative. Under multivariate analysis, significant factors for SSc associated with exposure to silica/solvents were: male gender (odds ratio 19.31, 95% confidence interval 15.34-69.86), cancer (odds ratio 5.97, 95% confidence interval 1.55-23.01), and digital ulcers (odds ratio 2.42, 95% confidence interval 1.05-5.56).</AbstractText><AbstractText Label="LIMITATIONS" NlmCategory="CONCLUSIONS">The cohort originated from a single geographic region.</AbstractText><AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Occupational exposure to crystalline silica/solvents is correlated with more severe forms of SSc characterized by: diffuse cutaneous involvement, interstitial lung disease, general microangiopathy (digital ulcers and myocardial dysfunction), and association with cancer. Occupational exposure should be systematically checked in all patients with SSc, as exposed patients seem to develop more severe forms of SSc.</AbstractText><CopyrightInformation>Copyright © 2014 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.</CopyrightInformation></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Marie</LastName><ForeName>Isabelle</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Centre Hospitalier Universitaire (CHU) Rouen, and Institut National de la Santé et de la Recherche Biomédicale (INSERM) Unit 905, University of Rouen Institut Fédératif Multidisciplinaire sur les Peptides (IFRMP), Institute for Biochemical Research, Rouen, France. Electronic address: isabelle.marie@chu-rouen.fr.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Menard</LastName><ForeName>Jean-François</ForeName><Initials>JF</Initials><AffiliationInfo><Affiliation>Department of Biostatistics, CHU Rouen, Rouen, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Duval-Modeste</LastName><ForeName>Anne-Bénédicte</ForeName><Initials>AB</Initials><AffiliationInfo><Affiliation>Department of Dermatology, CHU Rouen, Rouen, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Joly</LastName><ForeName>Pascal</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Dermatology, CHU Rouen, Rouen, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Dominique</LastName><ForeName>Stéphane</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Pneumology, CHU Rouen, Rouen, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bravard</LastName><ForeName>Pierre</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Dermatology, CHG Le Havre, Le Havre, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Noël</LastName><ForeName>David</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Centre Hospitalier Général (CHG) Elbeuf, Elbeuf, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Gehanno</LastName><ForeName>Jean-François</ForeName><Initials>JF</Initials><AffiliationInfo><Affiliation>Department of Occupational Medicine, CHU Rouen, Rouen, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Bubenheim</LastName><ForeName>Michael</ForeName><Initials>M</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, CHU Rouen, Rouen, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Benichou</LastName><ForeName>Jacques</ForeName><Initials>J</Initials><AffiliationInfo><Affiliation>Department of Epidemiology, CHU Rouen, Rouen, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Levesque</LastName><ForeName>Hervé</ForeName><Initials>H</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine, Centre Hospitalier Universitaire (CHU) Rouen, and Institut National de la Santé et de la Recherche Biomédicale (INSERM) Unit 905, University of Rouen Institut Fédératif Multidisciplinaire sur les Peptides (IFRMP), Institute for Biochemical Research, Rouen, France.</Affiliation></AffiliationInfo></Author></AuthorList><Language>ENG</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2015</Year><Month>Jan</Month><Day>10</Day></ArticleDate></Article><MedlineJournalInfo><Country>United States</Country><MedlineTA>J Am Acad Dermatol</MedlineTA><NlmUniqueID>7907132</NlmUniqueID><ISSNLinking>0190-9622</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D012997">Solvents</NameOfSubstance></Chemical><Chemical><RegistryNumber>7631-86-9</RegistryNumber><NameOfSubstance UI="D012822">Silicon Dioxide</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D009783" MajorTopicYN="N">Dermatitis, Occupational</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="Y">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016273" MajorTopicYN="N">Occupational Exposure</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="Y">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011446" MajorTopicYN="N">Prospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D045743" MajorTopicYN="N">Scleroderma, Diffuse</DescriptorName><QualifierName UI="Q000139" MajorTopicYN="N">chemically induced</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012595" MajorTopicYN="N">Scleroderma, Systemic</DescriptorName><QualifierName UI="Q000139" MajorTopicYN="Y">chemically induced</QualifierName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012822" MajorTopicYN="N">Silicon Dioxide</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="Y">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012997" MajorTopicYN="N">Solvents</DescriptorName><QualifierName UI="Q000009" MajorTopicYN="Y">adverse effects</QualifierName></MeshHeading></MeshHeadingList><KeywordList Owner="NOTNLM"><Keyword MajorTopicYN="N">cancer</Keyword><Keyword MajorTopicYN="N">crystalline silica</Keyword><Keyword MajorTopicYN="N">digital ulcers</Keyword><Keyword MajorTopicYN="N">interstitial lung disease</Keyword><Keyword MajorTopicYN="N">occupational factors</Keyword><Keyword MajorTopicYN="N">solvents</Keyword><Keyword MajorTopicYN="N">systemic sclerosis</Keyword></KeywordList></MedlineCitation><PubmedData><History><PubMedPubDate 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