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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">New Real-Time PCR Assay Using Locked Nucleic Acid Probes To Assess Prevalence of ParC Mutations in Fluoroquinolone-Susceptible <italic>Streptococcus pneumoniae</italic> Isolates from France</title><author><name sortKey="Decousser, Jean Winoc" sort="Decousser, Jean Winoc" uniqKey="Decousser J" first="Jean-Winoc" last="Decousser">Jean-Winoc Decousser</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Methlouthi, Imen" sort="Methlouthi, Imen" uniqKey="Methlouthi I" first="Imen" last="Methlouthi">Imen Methlouthi</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Pina, Patrick" sort="Pina, Patrick" uniqKey="Pina P" first="Patrick" last="Pina">Patrick Pina</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Collignon, Anne" sort="Collignon, Anne" uniqKey="Collignon A" first="Anne" last="Collignon">Anne Collignon</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Allouch, Pierre" sort="Allouch, Pierre" uniqKey="Allouch P" first="Pierre" last="Allouch">Pierre Allouch</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">16569894</idno><idno type="pmc">1426917</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1426917</idno><idno type="RBID">PMC:1426917</idno><idno type="doi">10.1128/AAC.50.4.1594-1598.2006</idno><date when="2006">2006</date><idno type="wicri:Area/Pmc/Corpus">000083</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">New Real-Time PCR Assay Using Locked Nucleic Acid Probes To Assess Prevalence of ParC Mutations in Fluoroquinolone-Susceptible <italic>Streptococcus pneumoniae</italic> Isolates from France</title><author><name sortKey="Decousser, Jean Winoc" sort="Decousser, Jean Winoc" uniqKey="Decousser J" first="Jean-Winoc" last="Decousser">Jean-Winoc Decousser</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Methlouthi, Imen" sort="Methlouthi, Imen" uniqKey="Methlouthi I" first="Imen" last="Methlouthi">Imen Methlouthi</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Pina, Patrick" sort="Pina, Patrick" uniqKey="Pina P" first="Patrick" last="Pina">Patrick Pina</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Collignon, Anne" sort="Collignon, Anne" uniqKey="Collignon A" first="Anne" last="Collignon">Anne Collignon</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Allouch, Pierre" sort="Allouch, Pierre" uniqKey="Allouch P" first="Pierre" last="Allouch">Pierre Allouch</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author></analytic><series><title level="j">Antimicrobial Agents and Chemotherapy</title><idno type="ISSN">0066-4804</idno><idno type="eISSN">1098-6596</idno><imprint><date when="2006">2006</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>A real-time PCR assay with locked nucleic acid probes was developed to screen mutations at codons 79 and 83 of the <italic>Streptococcus pneumoniae parC</italic> gene. Only silent mutations were detected among 236 French invasive fluoroquinolone-susceptible strains. This test could be useful for some high-risk patients or in national surveys.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Antimicrob Agents Chemother</journal-id><journal-id journal-id-type="publisher-id">aac</journal-id><journal-title>Antimicrobial Agents and Chemotherapy</journal-title><issn pub-type="ppub">0066-4804</issn><issn pub-type="epub">1098-6596</issn><publisher><publisher-name>American Society for Microbiology</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">16569894</article-id><article-id pub-id-type="pmc">1426917</article-id><article-id pub-id-type="publisher-id">0968-05</article-id><article-id pub-id-type="doi">10.1128/AAC.50.4.1594-1598.2006</article-id><article-categories><subj-group subj-group-type="heading"><subject>Mechanisms of Resistance</subject></subj-group></article-categories><title-group><article-title>New Real-Time PCR Assay Using Locked Nucleic Acid Probes To Assess Prevalence of ParC Mutations in Fluoroquinolone-Susceptible <italic>Streptococcus pneumoniae</italic> Isolates from France</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Decousser</surname><given-names>Jean-Winoc</given-names></name><xref ref-type="aff" rid="aff1">1</xref><xref ref-type="aff" rid="aff1">2</xref><xref ref-type="corresp" rid="cor1">*</xref></contrib><contrib contrib-type="author"><name><surname>Methlouthi</surname><given-names>Imen</given-names></name><xref ref-type="aff" rid="aff1">2</xref></contrib><contrib contrib-type="author"><name><surname>Pina</surname><given-names>Patrick</given-names></name><xref ref-type="aff" rid="aff1">3</xref></contrib><contrib contrib-type="author"><name><surname>Collignon</surname><given-names>Anne</given-names></name><xref ref-type="aff" rid="aff1">4</xref></contrib><contrib contrib-type="author"><name><surname>Allouch</surname><given-names>Pierre</given-names></name><xref ref-type="aff" rid="aff1">2</xref></contrib><contrib contrib-type="author"><collab>on behalf of the ColBVH Study Group</collab></contrib></contrib-group><aff id="aff1">Laboratoire de Biologie, Centre Hospitalier de Dourdan, Dourdan, France,<label>1</label> Service d'Hygiène Hospitalière, Centre Hospitalier de Versailles André Mignot, Versailles, France,<label>2</label> Service de Médecine B, Hôpital de Plaisir Grignon, Plaisir Grignon, France,<label>3</label> Laboratoire de Microbiologie, Centre Hospitalier Universitaire Jean Verdier, Bondy, France<label>4</label></aff><author-notes><fn id="cor1"><label>*</label><p>Corresponding author. Mailing address: Laboratoire de Biologie, Centre Hospitalier de Dourdan, 2 Rue du Potelet, 91415 Dourdan, France. Phone: (33) 1 60 81 58 92. Fax: (33) 1 60 81 58 97. E-mail: <email>jean-winoc.decousser@wanadoo.fr</email>.</p></fn></author-notes><pub-date pub-type="ppub"><month>4</month><year>2006</year></pub-date><volume>50</volume><issue>4</issue><fpage>1594</fpage><lpage>1598</lpage><history><date date-type="received"><day>3</day><month>8</month><year>2005</year></date><date date-type="rev-recd"><day>4</day><month>9</month><year>2005</year></date><date date-type="accepted"><day>5</day><month>1</month><year>2006</year></date></history><copyright-statement>Copyright © 2006, American Society for Microbiology</copyright-statement><copyright-year>2006</copyright-year><abstract><p>A real-time PCR assay with locked nucleic acid probes was developed to screen mutations at codons 79 and 83 of the <italic>Streptococcus pneumoniae parC</italic> gene. Only silent mutations were detected among 236 French invasive fluoroquinolone-susceptible strains. This test could be useful for some high-risk patients or in national surveys.</p></abstract><custom-meta-wrap><custom-meta><meta-name>PDF filename</meta-name><meta-value>zac00406001594</meta-value></custom-meta></custom-meta-wrap></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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