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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Surgical management of 552 carcinomas of the extrahepatic bile ducts (gallbladder and periampullary tumors excluded). Results of the French Surgical Association Survey.</title><author><name sortKey="Reding, R" sort="Reding, R" uniqKey="Reding R" first="R" last="Reding">R. Reding</name></author><author><name sortKey="Buard, J L" sort="Buard, J L" uniqKey="Buard J" first="J L" last="Buard">J L Buard</name></author><author><name sortKey="Lebeau, G" sort="Lebeau, G" uniqKey="Lebeau G" first="G" last="Lebeau">G. Lebeau</name></author><author><name sortKey="Launois, B" sort="Launois, B" uniqKey="Launois B" first="B" last="Launois">B. Launois</name></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">1705417</idno><idno type="pmc">1358334</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1358334</idno><idno type="RBID">PMC:1358334</idno><date when="1991">1991</date><idno type="wicri:Area/Pmc/Corpus">000079</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Surgical management of 552 carcinomas of the extrahepatic bile ducts (gallbladder and periampullary tumors excluded). Results of the French Surgical Association Survey.</title><author><name sortKey="Reding, R" sort="Reding, R" uniqKey="Reding R" first="R" last="Reding">R. Reding</name></author><author><name sortKey="Buard, J L" sort="Buard, J L" uniqKey="Buard J" first="J L" last="Buard">J L Buard</name></author><author><name sortKey="Lebeau, G" sort="Lebeau, G" uniqKey="Lebeau G" first="G" last="Lebeau">G. Lebeau</name></author><author><name sortKey="Launois, B" sort="Launois, B" uniqKey="Launois B" first="B" last="Launois">B. Launois</name></author></analytic><series><title level="j">Annals of Surgery</title><idno type="ISSN">0003-4932</idno><idno type="eISSN">1528-1140</idno><imprint><date when="1991">1991</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Five hundred fifty-two cases of primary carcinoma of the extrahepatic bile ducts (gallbladder and periampullary tumors excluded) collected from 55 surgical centers were reviewed retrospectively. Three hundred seven patients (56%) had upper-third lesions (proximal carcinoma), whereas 71 (13%) and 101 (18%), respectively, had middle-third and lower-third bile duct carcinomas. The remaining patients had diffuse lesions. Resectability rates were 32% for upper-third localization compared to 47% and 51% for middle-third and lower-third localization, respectively. The operative mortality rate for proximal carcinomas was significantly lower with resection (16%) compared with palliative surgery (31%) (p less than 0.05). Overall 1-year survival (operative deaths excluded) was 68% after tumor resection compared to 31% after palliative surgery (p less than 0.001). Long-term results after surgical resection correlated with local and regional extension of the disease. The results of this study show that resection of extrahepatic bile duct carcinomas, particularly in an upper-third localization, often is associated with worthwhile long-term survival.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Ann Surg</journal-id><journal-title>Annals of Surgery</journal-title><issn pub-type="ppub">0003-4932</issn><issn pub-type="epub">1528-1140</issn></journal-meta><article-meta><article-id pub-id-type="pmid">1705417</article-id><article-id pub-id-type="pmc">1358334</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title>Surgical management of 552 carcinomas of the extrahepatic bile ducts (gallbladder and periampullary tumors excluded). Results of the French Surgical Association Survey.</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>Reding</surname><given-names>R</given-names></name></contrib><contrib contrib-type="author"><name><surname>Buard</surname><given-names>J L</given-names></name></contrib><contrib contrib-type="author"><name><surname>Lebeau</surname><given-names>G</given-names></name></contrib><contrib contrib-type="author"><name><surname>Launois</surname><given-names>B</given-names></name></contrib></contrib-group><aff>Clinique Chirurgicale, Hôpital de Pontchaillou, Centre Hospitalo-Universitaire, Rennes, France.</aff><pub-date pub-type="ppub"><month>3</month><year>1991</year></pub-date><volume>213</volume><issue>3</issue><fpage>236</fpage><lpage>241</lpage><abstract><p>Five hundred fifty-two cases of primary carcinoma of the extrahepatic bile ducts (gallbladder and periampullary tumors excluded) collected from 55 surgical centers were reviewed retrospectively. Three hundred seven patients (56%) had upper-third lesions (proximal carcinoma), whereas 71 (13%) and 101 (18%), respectively, had middle-third and lower-third bile duct carcinomas. The remaining patients had diffuse lesions. Resectability rates were 32% for upper-third localization compared to 47% and 51% for middle-third and lower-third localization, respectively. The operative mortality rate for proximal carcinomas was significantly lower with resection (16%) compared with palliative surgery (31%) (p less than 0.05). Overall 1-year survival (operative deaths excluded) was 68% after tumor resection compared to 31% after palliative surgery (p less than 0.001). Long-term results after surgical resection correlated with local and regional extension of the disease. The results of this study show that resection of extrahepatic bile duct carcinomas, particularly in an upper-third localization, often is associated with worthwhile long-term survival.</p></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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