[Investigations for etiologic causes in community-acquired pneumonia in children (besides imagery)].
Identifieur interne : 000002 ( Ncbi/Merge ); précédent : 000001; suivant : 000003[Investigations for etiologic causes in community-acquired pneumonia in children (besides imagery)].
Auteurs : P. Le Roux [France]Source :
- Archives de pediatrie : organe officiel de la Societe francaise de pediatrie [ 0929-693X ] ; 1998.
English descriptors
- KwdEn :
- Biomarkers (blood), C-Reactive Protein (analysis), Child, Clinical Laboratory Techniques, Community-Acquired Infections (diagnosis), Diagnosis, Differential, Humans, Leukocyte Count, Pneumonia, Bacterial (diagnosis), Pneumonia, Viral (diagnosis), Predictive Value of Tests, Sensitivity and Specificity.
- MESH :
- chemical , analysis : C-Reactive Protein.
- chemical , blood : Biomarkers.
- diagnosis : Community-Acquired Infections, Pneumonia, Bacterial, Pneumonia, Viral.
- Child, Clinical Laboratory Techniques, Diagnosis, Differential, Humans, Leukocyte Count, Predictive Value of Tests, Sensitivity and Specificity.
Abstract
The aim of laboratory investigations in acute lower respiratory tract infections in children is mainly to help to differentiate bacterial from viral infections. While blood cell counts and C reactive protein have good negative predictive value and specificity. Blood cultures are at the best positive in 10% of bacterial pneumonia. Immunofluorescence bacterial antigen detection in nasopharyngeal secretions are useful for the etiological diagnosis of viral pneumonia while polymerase chain reaction technique remains at the present time too expensive to be routinely used. Bronchoalveolar lavage is only indicated in respiratory infections that resist a first line well conducted treatment.
PubMed: 10223159
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pubmed:10223159Le document en format XML
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Le Roux</name><affiliation wicri:level="1"><nlm:affiliation>Département de pédiatrie, centre hospitalier, Le Havre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Département de pédiatrie, centre hospitalier, Le Havre</wicri:regionArea><placeName><settlement type="city">Le Havre</settlement></placeName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1998">1998</date><idno type="RBID">pubmed:10223159</idno><idno type="pmid">10223159</idno><idno type="wicri:Area/PubMed/Corpus">000412</idno><idno type="wicri:Area/PubMed/Curation">000412</idno><idno type="wicri:Area/PubMed/Checkpoint">000412</idno><idno type="wicri:Area/Ncbi/Merge">000002</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">[Investigations for etiologic causes in community-acquired pneumonia in children (besides imagery)].</title><author><name sortKey="Le Roux, P" sort="Le Roux, P" uniqKey="Le Roux P" first="P" last="Le Roux">P. Le Roux</name><affiliation wicri:level="1"><nlm:affiliation>Département de pédiatrie, centre hospitalier, Le Havre, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Département de pédiatrie, centre hospitalier, Le Havre</wicri:regionArea><placeName><settlement type="city">Le Havre</settlement></placeName></affiliation></author></analytic><series><title level="j">Archives de pediatrie : organe officiel de la Societe francaise de pediatrie</title><idno type="ISSN">0929-693X</idno><imprint><date when="1998" type="published">1998</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Biomarkers (blood)</term><term>C-Reactive Protein (analysis)</term><term>Child</term><term>Clinical Laboratory Techniques</term><term>Community-Acquired Infections (diagnosis)</term><term>Diagnosis, Differential</term><term>Humans</term><term>Leukocyte Count</term><term>Pneumonia, Bacterial (diagnosis)</term><term>Pneumonia, Viral (diagnosis)</term><term>Predictive Value of Tests</term><term>Sensitivity and Specificity</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>C-Reactive Protein</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Biomarkers</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Community-Acquired Infections</term><term>Pneumonia, Bacterial</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Child</term><term>Clinical Laboratory Techniques</term><term>Diagnosis, Differential</term><term>Humans</term><term>Leukocyte Count</term><term>Predictive Value of Tests</term><term>Sensitivity and Specificity</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The aim of laboratory investigations in acute lower respiratory tract infections in children is mainly to help to differentiate bacterial from viral infections. While blood cell counts and C reactive protein have good negative predictive value and specificity. Blood cultures are at the best positive in 10% of bacterial pneumonia. Immunofluorescence bacterial antigen detection in nasopharyngeal secretions are useful for the etiological diagnosis of viral pneumonia while polymerase chain reaction technique remains at the present time too expensive to be routinely used. Bronchoalveolar lavage is only indicated in respiratory infections that resist a first line well conducted treatment.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">10223159</PMID><DateCreated><Year>1999</Year><Month>5</Month><Day>19</Day></DateCreated><DateCompleted><Year>1999</Year><Month>05</Month><Day>19</Day></DateCompleted><DateRevised><Year>2015</Year><Month>11</Month><Day>19</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0929-693X</ISSN><JournalIssue CitedMedium="Print"><Volume>5 Suppl 1</Volume><PubDate><Year>1998</Year></PubDate></JournalIssue><Title>Archives de pediatrie : organe officiel de la Societe francaise de pediatrie</Title><ISOAbbreviation>Arch Pediatr</ISOAbbreviation></Journal><ArticleTitle>[Investigations for etiologic causes in community-acquired pneumonia in children (besides imagery)].</ArticleTitle><Pagination><MedlinePgn>28s-32s</MedlinePgn></Pagination><Abstract><AbstractText>The aim of laboratory investigations in acute lower respiratory tract infections in children is mainly to help to differentiate bacterial from viral infections. While blood cell counts and C reactive protein have good negative predictive value and specificity. Blood cultures are at the best positive in 10% of bacterial pneumonia. Immunofluorescence bacterial antigen detection in nasopharyngeal secretions are useful for the etiological diagnosis of viral pneumonia while polymerase chain reaction technique remains at the present time too expensive to be routinely used. Bronchoalveolar lavage is only indicated in respiratory infections that resist a first line well conducted treatment.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Le Roux</LastName><ForeName>P</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Département de pédiatrie, centre hospitalier, Le Havre, France.</Affiliation></AffiliationInfo></Author></AuthorList><Language>FRE</Language><PublicationTypeList><PublicationType UI="D004740">English Abstract</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><VernacularTitle>Les examens à visée étiologique dans les pneumopathies communautaires de l'enfant (hors imagerie).</VernacularTitle></Article><MedlineJournalInfo><Country>France</Country><MedlineTA>Arch Pediatr</MedlineTA><NlmUniqueID>9421356</NlmUniqueID><ISSNLinking>0929-693X</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D015415">Biomarkers</NameOfSubstance></Chemical><Chemical><RegistryNumber>9007-41-4</RegistryNumber><NameOfSubstance UI="D002097">C-Reactive Protein</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D015415" MajorTopicYN="N">Biomarkers</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002097" MajorTopicYN="N">C-Reactive Protein</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002648" MajorTopicYN="N">Child</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D019411" MajorTopicYN="N">Clinical Laboratory Techniques</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D017714" MajorTopicYN="N">Community-Acquired Infections</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003937" MajorTopicYN="N">Diagnosis, Differential</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007958" MajorTopicYN="N">Leukocyte Count</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018410" MajorTopicYN="N">Pneumonia, Bacterial</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011024" MajorTopicYN="N">Pneumonia, Viral</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="Y">diagnosis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D011237" MajorTopicYN="N">Predictive Value of Tests</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012680" MajorTopicYN="N">Sensitivity and Specificity</DescriptorName></MeshHeading></MeshHeadingList><NumberOfReferences>26</NumberOfReferences></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1999</Year><Month>5</Month><Day>1</Day><Hour>2</Hour><Minute>11</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2000</Year><Month>5</Month><Day>5</Day><Hour>9</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1999</Year><Month>5</Month><Day>1</Day><Hour>2</Hour><Minute>11</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">10223159</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>France</li></country><settlement><li>Le Havre</li></settlement></list><tree><country name="France"><noRegion><name sortKey="Le Roux, P" sort="Le Roux, P" uniqKey="Le Roux P" first="P" last="Le Roux">P. 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