Results Obtained with Various Antifungal Susceptibility Testing Methods Do Not Predict Early Clinical Outcome in Patients with Cryptococcosis
Identifieur interne : 000158 ( Ncbi/Curation ); précédent : 000157; suivant : 000159Results Obtained with Various Antifungal Susceptibility Testing Methods Do Not Predict Early Clinical Outcome in Patients with Cryptococcosis
Auteurs : E. Dannaoui ; M. Abdul ; M. Arpin ; A. Michel-Nguyen ; M. A. Piens ; A. Favel ; O. Lortholary ; F. DromerSource :
- Antimicrobial Agents and Chemotherapy [ 0066-4804 ] ; 2006.
Abstract
The in vitro susceptibilities of
Url:
DOI: 10.1128/AAC.01520-05
PubMed: 16801427
PubMed Central: 1489793
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: Pour aller vers cette notice dans l'étape Curation :000084
- to stream Pmc, to step Curation: Pour aller vers cette notice dans l'étape Curation :000082
- to stream Pmc, to step Checkpoint: Pour aller vers cette notice dans l'étape Curation :000130
- to stream Ncbi, to step Merge: Pour aller vers cette notice dans l'étape Curation :000158
Links to Exploration step
PMC:1489793Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Results Obtained with Various Antifungal Susceptibility Testing Methods Do Not Predict Early Clinical Outcome in Patients with Cryptococcosis</title>
<author><name sortKey="Dannaoui, E" sort="Dannaoui, E" uniqKey="Dannaoui E" first="E." last="Dannaoui">E. Dannaoui</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Abdul, M" sort="Abdul, M" uniqKey="Abdul M" first="M." last="Abdul">M. Abdul</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Arpin, M" sort="Arpin, M" uniqKey="Arpin M" first="M." last="Arpin">M. Arpin</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Michel Nguyen, A" sort="Michel Nguyen, A" uniqKey="Michel Nguyen A" first="A." last="Michel-Nguyen">A. Michel-Nguyen</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Piens, M A" sort="Piens, M A" uniqKey="Piens M" first="M. A." last="Piens">M. A. Piens</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Favel, A" sort="Favel, A" uniqKey="Favel A" first="A." last="Favel">A. Favel</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lortholary, O" sort="Lortholary, O" uniqKey="Lortholary O" first="O." last="Lortholary">O. Lortholary</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Dromer, F" sort="Dromer, F" uniqKey="Dromer F" first="F." last="Dromer">F. Dromer</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmid">16801427</idno>
<idno type="pmc">1489793</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1489793</idno>
<idno type="RBID">PMC:1489793</idno>
<idno type="doi">10.1128/AAC.01520-05</idno>
<date when="2006">2006</date>
<idno type="wicri:Area/Pmc/Corpus">000084</idno>
<idno type="wicri:Area/Pmc/Curation">000082</idno>
<idno type="wicri:Area/Pmc/Checkpoint">000130</idno>
<idno type="wicri:Area/Ncbi/Merge">000158</idno>
<idno type="wicri:Area/Ncbi/Curation">000158</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Results Obtained with Various Antifungal Susceptibility Testing Methods Do Not Predict Early Clinical Outcome in Patients with Cryptococcosis</title>
<author><name sortKey="Dannaoui, E" sort="Dannaoui, E" uniqKey="Dannaoui E" first="E." last="Dannaoui">E. Dannaoui</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Abdul, M" sort="Abdul, M" uniqKey="Abdul M" first="M." last="Abdul">M. Abdul</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Arpin, M" sort="Arpin, M" uniqKey="Arpin M" first="M." last="Arpin">M. Arpin</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Michel Nguyen, A" sort="Michel Nguyen, A" uniqKey="Michel Nguyen A" first="A." last="Michel-Nguyen">A. Michel-Nguyen</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Piens, M A" sort="Piens, M A" uniqKey="Piens M" first="M. A." last="Piens">M. A. Piens</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Favel, A" sort="Favel, A" uniqKey="Favel A" first="A." last="Favel">A. Favel</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Lortholary, O" sort="Lortholary, O" uniqKey="Lortholary O" first="O." last="Lortholary">O. Lortholary</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
<author><name sortKey="Dromer, F" sort="Dromer, F" uniqKey="Dromer F" first="F." last="Dromer">F. Dromer</name>
<affiliation><nlm:aff id="aff1"></nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Antimicrobial Agents and Chemotherapy</title>
<idno type="ISSN">0066-4804</idno>
<idno type="eISSN">1098-6596</idno>
<imprint><date when="2006">2006</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass></textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en"><p>The in vitro susceptibilities of <italic>Cryptococcus neoformans</italic>
isolates from consecutive human immunodeficiency virus-positive and -negative patients to the antifungal agents fluconazole, amphotericin B, and flucytosine were determined by different techniques, including the CLSI method, Etest, and broth microdilution in yeast nitrogen base (YNB) medium, during a multicenter prospective study in France. The relationship between the in vitro data and the clinical outcome 2 weeks after the initiation of antifungal therapy was assessed. In addition, the correlation between the strain serotype and the in vitro activities of the antifungals was determined, and the susceptibility results obtained with the different techniques were also compared. Thirty-seven patients received a combination of amphotericin B with flucytosine as first-line therapy, 22 were treated with amphotericin B alone, and 15 received fluconazole alone. Whatever the antifungal tested, there was no trend toward higher MICs for strains isolated from patients who failed to respond to a given therapy compared to those from patients who did not with either the CLSI method, Etest, or broth microdilution in YNB medium. The MICs obtained by the CLSI or Etest method were significantly lower for serotype D strains than for serotype A strains for both fluconazole and amphotericin B, while flucytosine MICs were not different according to serotype. These findings suggest that the in vitro antifungal susceptibility of <italic>C. neoformans</italic>
, as determined with the techniques used, is not able to predict the early clinical outcome in patients with cryptococcosis.</p>
</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/France/explor/LeHavreV1/Data/Ncbi/Curation
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000158 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd -nk 000158 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/France |area= LeHavreV1 |flux= Ncbi |étape= Curation |type= RBID |clé= PMC:1489793 |texte= Results Obtained with Various Antifungal Susceptibility Testing Methods Do Not Predict Early Clinical Outcome in Patients with Cryptococcosis }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Ncbi/Curation/RBID.i -Sk "pubmed:16801427" \ | HfdSelect -Kh $EXPLOR_AREA/Data/Ncbi/Curation/biblio.hfd \ | NlmPubMed2Wicri -a LeHavreV1
This area was generated with Dilib version V0.6.25. |