Real-life conditions of use of sodium phosphate tablets for colon cleansing before colonoscopy
Identifieur interne : 000164 ( Main/Exploration ); précédent : 000163; suivant : 000165Real-life conditions of use of sodium phosphate tablets for colon cleansing before colonoscopy
Auteurs : Hervé Hagège ; René Laugier ; Stéphane Nahon ; Pierre Coulom ; Corinne Isnard-Bagnis ; Annaïck Albert-MartySource :
- Endoscopy International Open [ 2364-3722 ] ; 2015.
Abstract
Url:
DOI: 10.1055/s-0034-1391847
PubMed: 26357680
PubMed Central: 4554515
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Real-life conditions of use of sodium phosphate tablets for colon cleansing before colonoscopy</title><author><name sortKey="Hagege, Herve" sort="Hagege, Herve" uniqKey="Hagege H" first="Hervé" last="Hagège">Hervé Hagège</name><affiliation><nlm:aff id="AF124-1"><institution>CHI de Créteil, Service d’Hépato-gastroentérologie, Créteil, France</institution></nlm:aff></affiliation></author><author><name sortKey="Laugier, Rene" sort="Laugier, Rene" uniqKey="Laugier R" first="René" last="Laugier">René Laugier</name><affiliation><nlm:aff id="AF124-2"><institution>Hôpital de la Timone, Service de Gastroentérologie, Marseille, France</institution></nlm:aff></affiliation></author><author><name sortKey="Nahon, Stephane" sort="Nahon, Stephane" uniqKey="Nahon S" first="Stéphane" last="Nahon">Stéphane Nahon</name><affiliation><nlm:aff id="AF124-3"><institution>GHI Le Raincy-Montfermeil, Service de Gastroentérologie, Montfermeil, France</institution></nlm:aff></affiliation></author><author><name sortKey="Coulom, Pierre" sort="Coulom, Pierre" uniqKey="Coulom P" first="Pierre" last="Coulom">Pierre Coulom</name><affiliation><nlm:aff id="AF124-4"><institution>Clinique Saint-Jean Languedoc, Service de Gastroentérologie et Hépatologie, Toulouse, France</institution></nlm:aff></affiliation></author><author><name sortKey="Isnard Bagnis, Corinne" sort="Isnard Bagnis, Corinne" uniqKey="Isnard Bagnis C" first="Corinne" last="Isnard-Bagnis">Corinne Isnard-Bagnis</name><affiliation><nlm:aff id="AF124-5"><institution>Service de Néphrologie, Hôpital de la Pitié-Salpêtrière, Paris, France</institution></nlm:aff></affiliation></author><author><name sortKey="Albert Marty, Annaick" sort="Albert Marty, Annaick" uniqKey="Albert Marty A" first="Annaïck" last="Albert-Marty">Annaïck Albert-Marty</name><affiliation><nlm:aff id="AF124-6"><institution>Département de Pharmacovigilance, Mayoly-Spindler, Chatou, France.</institution></nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26357680</idno><idno type="pmc">4554515</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554515</idno><idno type="RBID">PMC:4554515</idno><idno type="doi">10.1055/s-0034-1391847</idno><date when="2015">2015</date><idno type="wicri:Area/Pmc/Corpus">000001</idno><idno type="wicri:Area/Pmc/Curation">000001</idno><idno type="wicri:Area/Pmc/Checkpoint">000018</idno><idno type="wicri:Area/Ncbi/Merge">000499</idno><idno type="wicri:Area/Ncbi/Curation">000499</idno><idno type="wicri:Area/Ncbi/Checkpoint">000499</idno><idno type="wicri:doubleKey">2364-3722:2015:Hagege H:real:life:conditions</idno><idno type="wicri:Area/Main/Merge">000162</idno><idno type="wicri:Area/Main/Curation">000164</idno><idno type="wicri:Area/Main/Exploration">000164</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Real-life conditions of use of sodium phosphate tablets for colon cleansing before colonoscopy</title><author><name sortKey="Hagege, Herve" sort="Hagege, Herve" uniqKey="Hagege H" first="Hervé" last="Hagège">Hervé Hagège</name><affiliation><nlm:aff id="AF124-1"><institution>CHI de Créteil, Service d’Hépato-gastroentérologie, Créteil, France</institution></nlm:aff></affiliation></author><author><name sortKey="Laugier, Rene" sort="Laugier, Rene" uniqKey="Laugier R" first="René" last="Laugier">René Laugier</name><affiliation><nlm:aff id="AF124-2"><institution>Hôpital de la Timone, Service de Gastroentérologie, Marseille, France</institution></nlm:aff></affiliation></author><author><name sortKey="Nahon, Stephane" sort="Nahon, Stephane" uniqKey="Nahon S" first="Stéphane" last="Nahon">Stéphane Nahon</name><affiliation><nlm:aff id="AF124-3"><institution>GHI Le Raincy-Montfermeil, Service de Gastroentérologie, Montfermeil, France</institution></nlm:aff></affiliation></author><author><name sortKey="Coulom, Pierre" sort="Coulom, Pierre" uniqKey="Coulom P" first="Pierre" last="Coulom">Pierre Coulom</name><affiliation><nlm:aff id="AF124-4"><institution>Clinique Saint-Jean Languedoc, Service de Gastroentérologie et Hépatologie, Toulouse, France</institution></nlm:aff></affiliation></author><author><name sortKey="Isnard Bagnis, Corinne" sort="Isnard Bagnis, Corinne" uniqKey="Isnard Bagnis C" first="Corinne" last="Isnard-Bagnis">Corinne Isnard-Bagnis</name><affiliation><nlm:aff id="AF124-5"><institution>Service de Néphrologie, Hôpital de la Pitié-Salpêtrière, Paris, France</institution></nlm:aff></affiliation></author><author><name sortKey="Albert Marty, Annaick" sort="Albert Marty, Annaick" uniqKey="Albert Marty A" first="Annaïck" last="Albert-Marty">Annaïck Albert-Marty</name><affiliation><nlm:aff id="AF124-6"><institution>Département de Pharmacovigilance, Mayoly-Spindler, Chatou, France.</institution></nlm:aff></affiliation></author></analytic><series><title level="j">Endoscopy International Open</title><idno type="ISSN">2364-3722</idno><idno type="eISSN">2196-9736</idno><imprint><date when="2015">2015</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><bold>Background and study aims:</bold> The purpose of this study was to describe the real-life conditions of use, efficacy, safety, and acceptability of sodium phosphate (NaP) tablets for colon cleansing in routine medical practice in France.</p><p><bold>Patients and methods:</bold> A total of 996 patients undergoing bowel preparation were enrolled by 108 gastroenterologists in this observational, longitudinal, prospective, multicenter study. The conditions of use of NaP tablets were assessed with a composite endpoint, which included six criteria for patient compliance with the recommended administration scheme and a criterion for the absence of contraindications to NaP use.</p><p><bold>Results:</bold> Adequate use of NaP was reported for 75.1 % of the patients. The main reasons for misuse were a smaller fluid intake than expected with a dose of 4 tablets and noncompliance with age-related contraindications. The quality of cleansing was satisfactory: the Boston Bowel Preparation Scale (BBPS) total score was 7 or higher in 75.4 % of the patients. Gastroscopy associated with colonoscopy in 38.9 % of the patients revealed gastric lesions, which were considered as possibly related to the use of NaP tablets in 10.3 % of them. Vomiting occurred in 9.8 % of the patients, and 0.6 % discontinued bowel preparation after an adverse event. No electrolyte disorders or renal impairment was reported, even if not systematically sought. The acceptability of the NaP tablets was high, particularly among patients who previously had undergone other methods of bowel preparation. </p><p><bold>Conclusions:</bold> Despite being defined according to strict criteria, adequate use of NaP tablets was observed in a high percentage of patients. The quality of colon cleansing and the safety and acceptability of NaP tablets were satisfactory and consistent with data from randomized clinical studies.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Quintero, E" uniqKey="Quintero E">E Quintero</name></author><author><name sortKey="Castells, A" uniqKey="Castells A">A Castells</name></author><author><name sortKey="Bujanda, L" uniqKey="Bujanda L">L Bujanda</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zauber, A G" uniqKey="Zauber A">A G Zauber</name></author><author><name sortKey="Winawer, S J" uniqKey="Winawer S">S J Winawer</name></author><author><name sortKey="O Brien, M J" uniqKey="O Brien M">M J O'Brien</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Froehlich, F" uniqKey="Froehlich F">F Froehlich</name></author><author><name sortKey="Wietlisbach, V" uniqKey="Wietlisbach V">V 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last="Coulom">Pierre Coulom</name><name sortKey="Hagege, Herve" sort="Hagege, Herve" uniqKey="Hagege H" first="Hervé" last="Hagège">Hervé Hagège</name><name sortKey="Isnard Bagnis, Corinne" sort="Isnard Bagnis, Corinne" uniqKey="Isnard Bagnis C" first="Corinne" last="Isnard-Bagnis">Corinne Isnard-Bagnis</name><name sortKey="Laugier, Rene" sort="Laugier, Rene" uniqKey="Laugier R" first="René" last="Laugier">René Laugier</name><name sortKey="Nahon, Stephane" sort="Nahon, Stephane" uniqKey="Nahon S" first="Stéphane" last="Nahon">Stéphane Nahon</name></noCountry></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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