[Inhaled bronchodilators and mucolytic agents in cystic fibrosis].
Identifieur interne : 001443 ( Main/Curation ); précédent : 001442; suivant : 001444[Inhaled bronchodilators and mucolytic agents in cystic fibrosis].
Auteurs : P. Le Roux [France] ; B. Le LuyerSource :
- Archives de pediatrie : organe officiel de la Societe francaise de pediatrie [ 0929-693X ] ; 2003.
English descriptors
- KwdEn :
- MESH :
- chemical , therapeutic use : Bronchodilator Agents, Deoxyribonucleases, Expectorants, Recombinant Proteins.
- drug therapy : Cystic Fibrosis.
- Administration, Inhalation, Humans.
Abstract
Poor clearance of airway secretions contributes to the pulmonary disease in cystic fibrosis (CF). Bronchodilator therapy might benefit in CF, but the efficacy is controversial. Effects of mucolytic agents have not been demonstrated conclusively. Only, efficacy of recombinant human deoxyribonuclease (rhDNase) is established with a rapid onset of benefit.
PubMed: 14671935
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pubmed:14671935Le document en format XML
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<author><name sortKey="Le Roux, P" sort="Le Roux, P" uniqKey="Le Roux P" first="P" last="Le Roux">P. Le Roux</name>
<affiliation wicri:level="3"><nlm:affiliation>Centre de ressources et de compétence dans la mucoviscidose, département de pédiatrie, groupe hospitalier, 55 bis, rue Gustave-Flaubert, 76600 Le Havre, France. pleroux@ch-havre.fr</nlm:affiliation>
<country xml:lang="fr">France</country>
<wicri:regionArea>Centre de ressources et de compétence dans la mucoviscidose, département de pédiatrie, groupe hospitalier, 55 bis, rue Gustave-Flaubert, 76600 Le Havre</wicri:regionArea>
<placeName><region type="region" nuts="2">Région Normandie</region>
<region type="old region" nuts="2">Haute-Normandie</region>
<settlement type="city">Le Havre</settlement>
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<author><name sortKey="Le Luyer, B" sort="Le Luyer, B" uniqKey="Le Luyer B" first="B" last="Le Luyer">B. Le Luyer</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">[Inhaled bronchodilators and mucolytic agents in cystic fibrosis].</title>
<author><name sortKey="Le Roux, P" sort="Le Roux, P" uniqKey="Le Roux P" first="P" last="Le Roux">P. Le Roux</name>
<affiliation wicri:level="3"><nlm:affiliation>Centre de ressources et de compétence dans la mucoviscidose, département de pédiatrie, groupe hospitalier, 55 bis, rue Gustave-Flaubert, 76600 Le Havre, France. pleroux@ch-havre.fr</nlm:affiliation>
<country xml:lang="fr">France</country>
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<author><name sortKey="Le Luyer, B" sort="Le Luyer, B" uniqKey="Le Luyer B" first="B" last="Le Luyer">B. Le Luyer</name>
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<series><title level="j">Archives de pediatrie : organe officiel de la Societe francaise de pediatrie</title>
<idno type="ISSN">0929-693X</idno>
<imprint><date when="2003" type="published">2003</date>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Administration, Inhalation</term>
<term>Bronchodilator Agents (therapeutic use)</term>
<term>Cystic Fibrosis (drug therapy)</term>
<term>Deoxyribonucleases (therapeutic use)</term>
<term>Expectorants (therapeutic use)</term>
<term>Humans</term>
<term>Recombinant Proteins (therapeutic use)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Bronchodilator Agents</term>
<term>Deoxyribonucleases</term>
<term>Expectorants</term>
<term>Recombinant Proteins</term>
</keywords>
<keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Cystic Fibrosis</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Administration, Inhalation</term>
<term>Humans</term>
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<front><div type="abstract" xml:lang="en">Poor clearance of airway secretions contributes to the pulmonary disease in cystic fibrosis (CF). Bronchodilator therapy might benefit in CF, but the efficacy is controversial. Effects of mucolytic agents have not been demonstrated conclusively. Only, efficacy of recombinant human deoxyribonuclease (rhDNase) is established with a rapid onset of benefit.</div>
</front>
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</record>
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