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Perioperative in-stent thrombosis after lung resection performed within 3 months of coronary stenting.

Identifieur interne : 000673 ( Hal/Checkpoint ); précédent : 000672; suivant : 000674

Perioperative in-stent thrombosis after lung resection performed within 3 months of coronary stenting.

Auteurs : Pierre-Yves Brichon [France] ; Philippe Boitet [France] ; Antoine Dujon [France] ; Jerôme Mouroux [France] ; Christophe Peillon [France] ; Marc Riquet [France] ; Jean-Francois Velly [France] ; Hans-Beat Ris [Suisse]

Source :

RBID : Hal:inserm-00173099

Abstract

BACKGROUND: Incidence of perioperative in-stent thrombosis associated with myocardial infarction in patients undergoing major lung resection within 3 months of coronary stenting. METHODS: Retrospective multi-institutional trial including all patients undergoing major lung resection (lobectomy or pneumonectomy) within 3 months of coronary stenting with non-drug-eluting stents between 1999 and 2004. RESULTS: There were 32 patients (29 men and 3 women), with age ranging from 46 to 82 years. One, two or four coronary stents were deployed in 72%, 22% and 6% of the patients, respectively. The time intervals between stenting and lung surgery were <30 days, 30-60 days and 61-90 days in 22%, 53% and 25% of the patients, respectively. All patients had dual antiplatelet therapy after stenting. Perioperative medication consisted of heparin alone or heparin plus aspirin in 34% and 66% of the patients, respectively. Perioperative in-stent thrombosis with myocardial infarction occurred in three patients (9%) with fatal outcome in one (3%). Twenty patients underwent lung resection after 4 weeks of dual antiplatelet therapy as recommended by the ACC/AHA Guideline Update; however, two out of three perioperative in-stent thrombosis occurred in this group of patients. CONCLUSIONS: Major lung resection performed within 3 months of coronary stenting may be complicated by perioperative in-stent thrombosis despite 4 weeks of dual antiplatelet therapy after stenting as recommended by the ACC/AHA Guideline Update.

Url:
DOI: 10.1016/j.ejcts.2006.08.012

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Le document en format XML

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<div type="abstract" xml:lang="en">BACKGROUND: Incidence of perioperative in-stent thrombosis associated with myocardial infarction in patients undergoing major lung resection within 3 months of coronary stenting. METHODS: Retrospective multi-institutional trial including all patients undergoing major lung resection (lobectomy or pneumonectomy) within 3 months of coronary stenting with non-drug-eluting stents between 1999 and 2004. RESULTS: There were 32 patients (29 men and 3 women), with age ranging from 46 to 82 years. One, two or four coronary stents were deployed in 72%, 22% and 6% of the patients, respectively. The time intervals between stenting and lung surgery were <30 days, 30-60 days and 61-90 days in 22%, 53% and 25% of the patients, respectively. All patients had dual antiplatelet therapy after stenting. Perioperative medication consisted of heparin alone or heparin plus aspirin in 34% and 66% of the patients, respectively. Perioperative in-stent thrombosis with myocardial infarction occurred in three patients (9%) with fatal outcome in one (3%). Twenty patients underwent lung resection after 4 weeks of dual antiplatelet therapy as recommended by the ACC/AHA Guideline Update; however, two out of three perioperative in-stent thrombosis occurred in this group of patients. CONCLUSIONS: Major lung resection performed within 3 months of coronary stenting may be complicated by perioperative in-stent thrombosis despite 4 weeks of dual antiplatelet therapy after stenting as recommended by the ACC/AHA Guideline Update.</div>
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<title xml:lang="en">Perioperative in-stent thrombosis after lung resection performed within 3 months of coronary stenting.</title>
<author role="aut">
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<forename type="first">Pierre-Yves</forename>
<surname>Brichon</surname>
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<idno type="halAuthorId">209520</idno>
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<forename type="first">Philippe</forename>
<surname>Boitet</surname>
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<forename type="first">Antoine</forename>
<surname>Dujon</surname>
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<idno type="halAuthorId">209522</idno>
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<forename type="first">Jerôme</forename>
<surname>Mouroux</surname>
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<idno type="halAuthorId">209523</idno>
<affiliation ref="#struct-44332"></affiliation>
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<author role="aut">
<persName>
<forename type="first">Christophe</forename>
<surname>Peillon</surname>
</persName>
<idno type="halAuthorId">209524</idno>
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<persName>
<forename type="first">Marc</forename>
<surname>Riquet</surname>
</persName>
<idno type="halAuthorId">209525</idno>
<affiliation ref="#struct-44334"></affiliation>
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<author role="aut">
<persName>
<forename type="first">Jean-Francois</forename>
<surname>Velly</surname>
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<idno type="halAuthorId">209526</idno>
<affiliation ref="#struct-44335"></affiliation>
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<author role="crp">
<persName>
<forename type="first">Hans-Beat</forename>
<surname>Ris</surname>
</persName>
<email>hans-beat.ris@chuv.ch</email>
<idno type="halAuthorId">209527</idno>
<affiliation ref="#struct-44336"></affiliation>
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<idno type="halJournalId" status="VALID">13016</idno>
<idno type="issn">1010-7940</idno>
<title level="j">European Journal of Cardio-Thoracic Surgery</title>
<imprint>
<publisher>Oxford University Press (OUP)</publisher>
<biblScope unit="volume">30</biblScope>
<biblScope unit="issue">5</biblScope>
<biblScope unit="pp">793-6</biblScope>
<date type="datePub">2006-11</date>
<date type="dateEpub">2006-09-22</date>
</imprint>
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<idno type="doi">10.1016/j.ejcts.2006.08.012</idno>
<idno type="pubmed">16996274</idno>
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<language ident="en">English</language>
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<classCode scheme="mesh">Aged, 80 and over</classCode>
<classCode scheme="mesh">Middle Aged</classCode>
<classCode scheme="mesh">Platelet Aggregation Inhibitors</classCode>
<classCode scheme="mesh">Pneumonectomy</classCode>
<classCode scheme="mesh">Postoperative Care</classCode>
<classCode scheme="mesh">Postoperative Complications</classCode>
<classCode scheme="mesh">Postoperative Period</classCode>
<classCode scheme="mesh">Retrospective Studies</classCode>
<classCode scheme="mesh">Stents</classCode>
<classCode scheme="mesh">Carcinoma, Non-Small-Cell Lung</classCode>
<classCode scheme="mesh">Coronary Disease</classCode>
<classCode scheme="mesh">Coronary Thrombosis</classCode>
<classCode scheme="mesh">Drug Administration Schedule</classCode>
<classCode scheme="mesh">Female</classCode>
<classCode scheme="mesh">Humans</classCode>
<classCode scheme="mesh">Lung Neoplasms</classCode>
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<abstract xml:lang="en">BACKGROUND: Incidence of perioperative in-stent thrombosis associated with myocardial infarction in patients undergoing major lung resection within 3 months of coronary stenting. METHODS: Retrospective multi-institutional trial including all patients undergoing major lung resection (lobectomy or pneumonectomy) within 3 months of coronary stenting with non-drug-eluting stents between 1999 and 2004. RESULTS: There were 32 patients (29 men and 3 women), with age ranging from 46 to 82 years. One, two or four coronary stents were deployed in 72%, 22% and 6% of the patients, respectively. The time intervals between stenting and lung surgery were <30 days, 30-60 days and 61-90 days in 22%, 53% and 25% of the patients, respectively. All patients had dual antiplatelet therapy after stenting. Perioperative medication consisted of heparin alone or heparin plus aspirin in 34% and 66% of the patients, respectively. Perioperative in-stent thrombosis with myocardial infarction occurred in three patients (9%) with fatal outcome in one (3%). Twenty patients underwent lung resection after 4 weeks of dual antiplatelet therapy as recommended by the ACC/AHA Guideline Update; however, two out of three perioperative in-stent thrombosis occurred in this group of patients. CONCLUSIONS: Major lung resection performed within 3 months of coronary stenting may be complicated by perioperative in-stent thrombosis despite 4 weeks of dual antiplatelet therapy after stenting as recommended by the ACC/AHA Guideline Update.</abstract>
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