Links to Exploration step
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Neolithic mitochondrial haplogroup H genomes and the genetic origins of Europeans</title><author><name sortKey="Brotherton, Paul" sort="Brotherton, Paul" uniqKey="Brotherton P" first="Paul" last="Brotherton">Paul Brotherton</name><affiliation><nlm:aff id="A1">The Australian Centre for Ancient DNA, University of Adelaide, Adelaide, South Australia 5005, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A2">Archaeogenetics Research Group, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK</nlm:aff></affiliation></author><author><name sortKey="Haak, Wolfgang" sort="Haak, Wolfgang" uniqKey="Haak W" first="Wolfgang" last="Haak">Wolfgang Haak</name><affiliation><nlm:aff id="A1">The Australian Centre for Ancient DNA, University of Adelaide, Adelaide, South Australia 5005, Australia</nlm:aff></affiliation></author><author><name sortKey="Templeton, Jennifer" sort="Templeton, Jennifer" uniqKey="Templeton J" first="Jennifer" last="Templeton">Jennifer Templeton</name><affiliation><nlm:aff id="A1">The Australian Centre for Ancient DNA, University of Adelaide, Adelaide, South Australia 5005, Australia</nlm:aff></affiliation></author><author><name sortKey="Brandt, Guido" sort="Brandt, Guido" uniqKey="Brandt G" first="Guido" last="Brandt">Guido Brandt</name><affiliation><nlm:aff id="A3">Institute of Anthropology, Colonel-Kleinmann Weg 2, Johannes Gutenberg University, Mainz, D-55128 Mainz, Germany</nlm:aff></affiliation></author><author><name sortKey="Soubrier, Julien" sort="Soubrier, Julien" uniqKey="Soubrier J" first="Julien" last="Soubrier">Julien Soubrier</name><affiliation><nlm:aff id="A1">The Australian Centre for Ancient DNA, University of Adelaide, Adelaide, South Australia 5005, Australia</nlm:aff></affiliation></author><author><name sortKey="Jane Adler, Christina" sort="Jane Adler, Christina" uniqKey="Jane Adler C" first="Christina" last="Jane Adler">Christina Jane Adler</name><affiliation><nlm:aff id="A1">The Australian Centre for Ancient DNA, University of Adelaide, Adelaide, South Australia 5005, Australia</nlm:aff></affiliation></author><author><name sortKey="Richards, Stephen M" sort="Richards, Stephen M" uniqKey="Richards S" first="Stephen M." last="Richards">Stephen M. Richards</name><affiliation><nlm:aff id="A1">The Australian Centre for Ancient DNA, University of Adelaide, Adelaide, South Australia 5005, Australia</nlm:aff></affiliation></author><author><name sortKey="Der Sarkissian, Clio" sort="Der Sarkissian, Clio" uniqKey="Der Sarkissian C" first="Clio" last="Der Sarkissian">Clio Der Sarkissian</name><affiliation><nlm:aff id="A1">The Australian Centre for Ancient DNA, University of Adelaide, Adelaide, South Australia 5005, Australia</nlm:aff></affiliation></author><author><name sortKey="Ganslmeier, Robert" sort="Ganslmeier, Robert" uniqKey="Ganslmeier R" first="Robert" last="Ganslmeier">Robert Ganslmeier</name><affiliation><nlm:aff id="A4">State Office for Heritage Management and Archaeology Saxony-Anhalt / State Museum for Prehistory Halle, Richard-Wagner-Straße 9, D-06114 Halle/Saale, Germany</nlm:aff></affiliation></author><author><name sortKey="Friederich, Susanne" sort="Friederich, Susanne" uniqKey="Friederich S" first="Susanne" last="Friederich">Susanne Friederich</name><affiliation><nlm:aff id="A4">State Office for Heritage Management and Archaeology Saxony-Anhalt / State Museum for Prehistory Halle, Richard-Wagner-Straße 9, D-06114 Halle/Saale, Germany</nlm:aff></affiliation></author><author><name sortKey="Dresely, Veit" sort="Dresely, Veit" uniqKey="Dresely V" first="Veit" last="Dresely">Veit Dresely</name><affiliation><nlm:aff id="A4">State Office for Heritage Management and Archaeology Saxony-Anhalt / State Museum for Prehistory Halle, Richard-Wagner-Straße 9, D-06114 Halle/Saale, Germany</nlm:aff></affiliation></author><author><name sortKey="Van Oven, Mannis" sort="Van Oven, Mannis" uniqKey="Van Oven M" first="Mannis" last="Van Oven">Mannis Van Oven</name><affiliation><nlm:aff id="A5">Department of Forensic Molecular Biology, Erasmus MC, University Medical Centre, Rotterdam, 3000 CA Rotterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Kenyon, Rosalie" sort="Kenyon, Rosalie" uniqKey="Kenyon R" first="Rosalie" last="Kenyon">Rosalie Kenyon</name><affiliation><nlm:aff id="A6">SA Pathology, Adelaide, South Australia 5000, Australia</nlm:aff></affiliation></author><author><name sortKey="Van Der Hoek, Mark B" sort="Van Der Hoek, Mark B" uniqKey="Van Der Hoek M" first="Mark B." last="Van Der Hoek">Mark B. Van Der Hoek</name><affiliation><nlm:aff id="A6">SA Pathology, Adelaide, South Australia 5000, Australia</nlm:aff></affiliation></author><author><name sortKey="Korlach, Jonas" sort="Korlach, Jonas" uniqKey="Korlach J" first="Jonas" last="Korlach">Jonas Korlach</name><affiliation><nlm:aff id="A7">Pacific Biosciences, USA</nlm:aff></affiliation></author><author><name sortKey="Luong, Khai" sort="Luong, Khai" uniqKey="Luong K" first="Khai" last="Luong">Khai Luong</name><affiliation><nlm:aff id="A7">Pacific Biosciences, USA</nlm:aff></affiliation></author><author><name sortKey="Ho, Simon Y W" sort="Ho, Simon Y W" uniqKey="Ho S" first="Simon Y. W." last="Ho">Simon Y. W. Ho</name><affiliation><nlm:aff id="A8">School of Biological Sciences, The University of Sydney, New South Wales 2006, Australia</nlm:aff></affiliation></author><author><name sortKey="Quintana Murci, Lluis" sort="Quintana Murci, Lluis" uniqKey="Quintana Murci L" first="Lluis" last="Quintana-Murci">Lluis Quintana-Murci</name><affiliation><nlm:aff id="A9">Institut Pasteur, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Behar, Doron M" sort="Behar, Doron M" uniqKey="Behar D" first="Doron M." last="Behar">Doron M. Behar</name><affiliation><nlm:aff id="A10">Rambam Medical Centre, 31096 Haifa, Israel</nlm:aff></affiliation></author><author><name sortKey="Meller, Harald" sort="Meller, Harald" uniqKey="Meller H" first="Harald" last="Meller">Harald Meller</name><affiliation><nlm:aff id="A4">State Office for Heritage Management and Archaeology Saxony-Anhalt / State Museum for Prehistory Halle, Richard-Wagner-Straße 9, D-06114 Halle/Saale, Germany</nlm:aff></affiliation></author><author><name sortKey="Alt, Kurt W" sort="Alt, Kurt W" uniqKey="Alt K" first="Kurt W." last="Alt">Kurt W. Alt</name><affiliation><nlm:aff id="A3">Institute of Anthropology, Colonel-Kleinmann Weg 2, Johannes Gutenberg University, Mainz, D-55128 Mainz, Germany</nlm:aff></affiliation></author><author><name sortKey="Cooper, Alan" sort="Cooper, Alan" uniqKey="Cooper A" first="Alan" last="Cooper">Alan Cooper</name><affiliation><nlm:aff id="A3">Institute of Anthropology, Colonel-Kleinmann Weg 2, Johannes Gutenberg University, Mainz, D-55128 Mainz, Germany</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">23612305</idno><idno type="pmc">3978205</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3978205</idno><idno type="RBID">PMC:3978205</idno><idno type="doi">10.1038/ncomms2656</idno><date when="2013">2013</date><idno type="wicri:Area/Pmc/Corpus">001E69</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">001E69</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Neolithic mitochondrial haplogroup H genomes and the genetic origins of Europeans</title><author><name sortKey="Brotherton, Paul" sort="Brotherton, Paul" uniqKey="Brotherton P" first="Paul" last="Brotherton">Paul Brotherton</name><affiliation><nlm:aff id="A1">The Australian Centre for Ancient DNA, University of Adelaide, Adelaide, South Australia 5005, Australia</nlm:aff></affiliation><affiliation><nlm:aff id="A2">Archaeogenetics Research Group, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK</nlm:aff></affiliation></author><author><name sortKey="Haak, Wolfgang" sort="Haak, Wolfgang" uniqKey="Haak W" first="Wolfgang" last="Haak">Wolfgang Haak</name><affiliation><nlm:aff id="A1">The Australian Centre for Ancient DNA, University of Adelaide, Adelaide, South Australia 5005, Australia</nlm:aff></affiliation></author><author><name sortKey="Templeton, Jennifer" sort="Templeton, Jennifer" uniqKey="Templeton J" first="Jennifer" last="Templeton">Jennifer Templeton</name><affiliation><nlm:aff id="A1">The Australian Centre for Ancient DNA, University of Adelaide, Adelaide, South Australia 5005, Australia</nlm:aff></affiliation></author><author><name sortKey="Brandt, Guido" sort="Brandt, Guido" uniqKey="Brandt G" first="Guido" last="Brandt">Guido Brandt</name><affiliation><nlm:aff id="A3">Institute of Anthropology, Colonel-Kleinmann Weg 2, Johannes Gutenberg University, Mainz, D-55128 Mainz, Germany</nlm:aff></affiliation></author><author><name sortKey="Soubrier, Julien" sort="Soubrier, Julien" uniqKey="Soubrier J" first="Julien" last="Soubrier">Julien Soubrier</name><affiliation><nlm:aff id="A1">The Australian Centre for Ancient DNA, University of Adelaide, Adelaide, South Australia 5005, Australia</nlm:aff></affiliation></author><author><name sortKey="Jane Adler, Christina" sort="Jane Adler, Christina" uniqKey="Jane Adler C" first="Christina" last="Jane Adler">Christina Jane Adler</name><affiliation><nlm:aff id="A1">The Australian Centre for Ancient DNA, University of Adelaide, Adelaide, South Australia 5005, Australia</nlm:aff></affiliation></author><author><name sortKey="Richards, Stephen M" sort="Richards, Stephen M" uniqKey="Richards S" first="Stephen M." last="Richards">Stephen M. Richards</name><affiliation><nlm:aff id="A1">The Australian Centre for Ancient DNA, University of Adelaide, Adelaide, South Australia 5005, Australia</nlm:aff></affiliation></author><author><name sortKey="Der Sarkissian, Clio" sort="Der Sarkissian, Clio" uniqKey="Der Sarkissian C" first="Clio" last="Der Sarkissian">Clio Der Sarkissian</name><affiliation><nlm:aff id="A1">The Australian Centre for Ancient DNA, University of Adelaide, Adelaide, South Australia 5005, Australia</nlm:aff></affiliation></author><author><name sortKey="Ganslmeier, Robert" sort="Ganslmeier, Robert" uniqKey="Ganslmeier R" first="Robert" last="Ganslmeier">Robert Ganslmeier</name><affiliation><nlm:aff id="A4">State Office for Heritage Management and Archaeology Saxony-Anhalt / State Museum for Prehistory Halle, Richard-Wagner-Straße 9, D-06114 Halle/Saale, Germany</nlm:aff></affiliation></author><author><name sortKey="Friederich, Susanne" sort="Friederich, Susanne" uniqKey="Friederich S" first="Susanne" last="Friederich">Susanne Friederich</name><affiliation><nlm:aff id="A4">State Office for Heritage Management and Archaeology Saxony-Anhalt / State Museum for Prehistory Halle, Richard-Wagner-Straße 9, D-06114 Halle/Saale, Germany</nlm:aff></affiliation></author><author><name sortKey="Dresely, Veit" sort="Dresely, Veit" uniqKey="Dresely V" first="Veit" last="Dresely">Veit Dresely</name><affiliation><nlm:aff id="A4">State Office for Heritage Management and Archaeology Saxony-Anhalt / State Museum for Prehistory Halle, Richard-Wagner-Straße 9, D-06114 Halle/Saale, Germany</nlm:aff></affiliation></author><author><name sortKey="Van Oven, Mannis" sort="Van Oven, Mannis" uniqKey="Van Oven M" first="Mannis" last="Van Oven">Mannis Van Oven</name><affiliation><nlm:aff id="A5">Department of Forensic Molecular Biology, Erasmus MC, University Medical Centre, Rotterdam, 3000 CA Rotterdam, The Netherlands</nlm:aff></affiliation></author><author><name sortKey="Kenyon, Rosalie" sort="Kenyon, Rosalie" uniqKey="Kenyon R" first="Rosalie" last="Kenyon">Rosalie Kenyon</name><affiliation><nlm:aff id="A6">SA Pathology, Adelaide, South Australia 5000, Australia</nlm:aff></affiliation></author><author><name sortKey="Van Der Hoek, Mark B" sort="Van Der Hoek, Mark B" uniqKey="Van Der Hoek M" first="Mark B." last="Van Der Hoek">Mark B. Van Der Hoek</name><affiliation><nlm:aff id="A6">SA Pathology, Adelaide, South Australia 5000, Australia</nlm:aff></affiliation></author><author><name sortKey="Korlach, Jonas" sort="Korlach, Jonas" uniqKey="Korlach J" first="Jonas" last="Korlach">Jonas Korlach</name><affiliation><nlm:aff id="A7">Pacific Biosciences, USA</nlm:aff></affiliation></author><author><name sortKey="Luong, Khai" sort="Luong, Khai" uniqKey="Luong K" first="Khai" last="Luong">Khai Luong</name><affiliation><nlm:aff id="A7">Pacific Biosciences, USA</nlm:aff></affiliation></author><author><name sortKey="Ho, Simon Y W" sort="Ho, Simon Y W" uniqKey="Ho S" first="Simon Y. W." last="Ho">Simon Y. W. Ho</name><affiliation><nlm:aff id="A8">School of Biological Sciences, The University of Sydney, New South Wales 2006, Australia</nlm:aff></affiliation></author><author><name sortKey="Quintana Murci, Lluis" sort="Quintana Murci, Lluis" uniqKey="Quintana Murci L" first="Lluis" last="Quintana-Murci">Lluis Quintana-Murci</name><affiliation><nlm:aff id="A9">Institut Pasteur, Paris, France</nlm:aff></affiliation></author><author><name sortKey="Behar, Doron M" sort="Behar, Doron M" uniqKey="Behar D" first="Doron M." last="Behar">Doron M. Behar</name><affiliation><nlm:aff id="A10">Rambam Medical Centre, 31096 Haifa, Israel</nlm:aff></affiliation></author><author><name sortKey="Meller, Harald" sort="Meller, Harald" uniqKey="Meller H" first="Harald" last="Meller">Harald Meller</name><affiliation><nlm:aff id="A4">State Office for Heritage Management and Archaeology Saxony-Anhalt / State Museum for Prehistory Halle, Richard-Wagner-Straße 9, D-06114 Halle/Saale, Germany</nlm:aff></affiliation></author><author><name sortKey="Alt, Kurt W" sort="Alt, Kurt W" uniqKey="Alt K" first="Kurt W." last="Alt">Kurt W. Alt</name><affiliation><nlm:aff id="A3">Institute of Anthropology, Colonel-Kleinmann Weg 2, Johannes Gutenberg University, Mainz, D-55128 Mainz, Germany</nlm:aff></affiliation></author><author><name sortKey="Cooper, Alan" sort="Cooper, Alan" uniqKey="Cooper A" first="Alan" last="Cooper">Alan Cooper</name><affiliation><nlm:aff id="A3">Institute of Anthropology, Colonel-Kleinmann Weg 2, Johannes Gutenberg University, Mainz, D-55128 Mainz, Germany</nlm:aff></affiliation></author></analytic><series><title level="j">Nature communications</title><idno type="eISSN">2041-1723</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p id="P6">Haplogroup (hg) H dominates present-day Western European mitochondrial (mt) DNA variability (>40%), yet was less common (~19%) amongst Early Neolithic farmers (~5450 BC) and virtually absent in Mesolithic hunter-gatherers. Here we investigate this major component of the maternal population history of modern Europeans and sequence 39 complete hg H mitochondrial genomes from ancient human remains. We then compare this ‘real-time’ genetic data with cultural changes taking place between the Early Neolithic (~5450 BC) and Bronze Age (~2200 BC) in Central Europe. Our results reveal that the current diversity and distribution of hg H were largely established by the Mid-Neolithic (~4000 BC), but with substantial genetic contributions from subsequent pan-European cultures such as the Bell Beakers expanding out of Iberia in the Late Neolithic (~2800 BC). Dated hg H genomes allow us to reconstruct the recent evolutionary history of hg H and reveal a mutation rate 45% higher than current estimates for human mitochondria.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<pmc-dir>properties manuscript</pmc-dir>
<front><journal-meta><journal-id journal-id-type="nlm-journal-id">101528555</journal-id><journal-id journal-id-type="pubmed-jr-id">37539</journal-id><journal-id journal-id-type="nlm-ta">Nat Commun</journal-id><journal-id journal-id-type="iso-abbrev">Nat Commun</journal-id><journal-title-group><journal-title>Nature communications</journal-title></journal-title-group><issn pub-type="epub">2041-1723</issn></journal-meta><article-meta><article-id pub-id-type="pmid">23612305</article-id><article-id pub-id-type="pmc">3978205</article-id><article-id pub-id-type="doi">10.1038/ncomms2656</article-id><article-id pub-id-type="manuscript">EMS57674</article-id><article-categories><subj-group subj-group-type="heading"><subject>Article</subject></subj-group></article-categories><title-group><article-title>Neolithic mitochondrial haplogroup H genomes and the genetic origins of Europeans</article-title></title-group><contrib-group><contrib contrib-type="author" equal-contrib="yes"><name><surname>Brotherton</surname><given-names>Paul</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="aff" rid="A2">2</xref><xref ref-type="corresp" rid="CR1">*</xref></contrib><contrib contrib-type="author" equal-contrib="yes"><name><surname>Haak</surname><given-names>Wolfgang</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="corresp" rid="CR1">*</xref></contrib><contrib contrib-type="author"><name><surname>Templeton</surname><given-names>Jennifer</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Brandt</surname><given-names>Guido</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Soubrier</surname><given-names>Julien</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Jane Adler</surname><given-names>Christina</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="author-notes" rid="FN1">12</xref></contrib><contrib contrib-type="author"><name><surname>Richards</surname><given-names>Stephen M.</given-names></name><xref ref-type="aff" rid="A1">1</xref></contrib><contrib contrib-type="author"><name><surname>Der Sarkissian</surname><given-names>Clio</given-names></name><xref ref-type="aff" rid="A1">1</xref><xref ref-type="author-notes" rid="FN2">13</xref></contrib><contrib contrib-type="author"><name><surname>Ganslmeier</surname><given-names>Robert</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>Friederich</surname><given-names>Susanne</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>Dresely</surname><given-names>Veit</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>van Oven</surname><given-names>Mannis</given-names></name><xref ref-type="aff" rid="A5">5</xref></contrib><contrib contrib-type="author"><name><surname>Kenyon</surname><given-names>Rosalie</given-names></name><xref ref-type="aff" rid="A6">6</xref></contrib><contrib contrib-type="author"><name><surname>Van der Hoek</surname><given-names>Mark B.</given-names></name><xref ref-type="aff" rid="A6">6</xref></contrib><contrib contrib-type="author"><name><surname>Korlach</surname><given-names>Jonas</given-names></name><xref ref-type="aff" rid="A7">7</xref></contrib><contrib contrib-type="author"><name><surname>Luong</surname><given-names>Khai</given-names></name><xref ref-type="aff" rid="A7">7</xref></contrib><contrib contrib-type="author"><name><surname>Ho</surname><given-names>Simon Y. W.</given-names></name><xref ref-type="aff" rid="A8">8</xref></contrib><contrib contrib-type="author"><name><surname>Quintana-Murci</surname><given-names>Lluis</given-names></name><xref ref-type="aff" rid="A9">9</xref></contrib><contrib contrib-type="author"><name><surname>Behar</surname><given-names>Doron M.</given-names></name><xref ref-type="aff" rid="A10">10</xref></contrib><contrib contrib-type="author"><name><surname>Meller</surname><given-names>Harald</given-names></name><xref ref-type="aff" rid="A4">4</xref></contrib><contrib contrib-type="author"><name><surname>Alt</surname><given-names>Kurt W.</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><name><surname>Cooper</surname><given-names>Alan</given-names></name><xref ref-type="aff" rid="A3">3</xref></contrib><contrib contrib-type="author"><collab>The Genographic Consortium</collab></contrib></contrib-group><aff id="A1"><label>1</label>The Australian Centre for Ancient DNA, University of Adelaide, Adelaide, South Australia 5005, Australia</aff><aff id="A2"><label>2</label>Archaeogenetics Research Group, School of Applied Sciences, University of Huddersfield, Queensgate, Huddersfield HD1 3DH, UK</aff><aff id="A3"><label>3</label>Institute of Anthropology, Colonel-Kleinmann Weg 2, Johannes Gutenberg University, Mainz, D-55128 Mainz, Germany</aff><aff id="A4"><label>4</label>State Office for Heritage Management and Archaeology Saxony-Anhalt / State Museum for Prehistory Halle, Richard-Wagner-Straße 9, D-06114 Halle/Saale, Germany</aff><aff id="A5"><label>5</label>Department of Forensic Molecular Biology, Erasmus MC, University Medical Centre, Rotterdam, 3000 CA Rotterdam, The Netherlands</aff><aff id="A6"><label>6</label>SA Pathology, Adelaide, South Australia 5000, Australia</aff><aff id="A7"><label>7</label>Pacific Biosciences, USA</aff><aff id="A8"><label>8</label>School of Biological Sciences, The University of Sydney, New South Wales 2006, Australia</aff><aff id="A9"><label>9</label>Institut Pasteur, Paris, France</aff><aff id="A10"><label>10</label>Rambam Medical Centre, 31096 Haifa, Israel</aff><author-notes><corresp id="CR1"><label>*</label>Correspondence and requests for materials should be addressed to W.H. (<email>wolfgang.haak@adelaide.edu.au</email>)</corresp><fn fn-type="present-address" id="FN1"><label>12</label><p id="P1">Current address: Institute of Dental Research, Westmead Centre for Oral Health, The University of Sydney, New South Wales 2145, Australia.</p></fn><fn fn-type="present-address" id="FN2"><label>13</label><p id="P2">Current address: Centre for Geogenetics, Natural History Museum of Denmark, 1350 Copenhagen, Denmark.</p></fn><fn id="FN3"><p id="P3"><bold>Members of The Genographic Consortium</bold>:</p><p id="P100"><bold>Syama Adhikarla, ArunKumar GaneshPrasad, Ramasamy Pitchappan, Arun Varatharajan Santhakumari</bold> Madurai Kamaraj University, Madurai, Tamil Nadu, India; <bold>Elena Balanovska, Oleg Balanovsky</bold> Research Centre for Medical Genetics, Russian Academy of Medical Sciences, Moscow, Russia; <bold>Jaume Bertranpetit, David Comas, Begoña Martínez-Cruz, Marta Melé</bold>, Universitat Pompeu Fabra, Barcelona, Spain; <bold>Andrew C. Clarke, Elizabeth A. Matisoo-Smith,</bold> University of Otago, Dunedin, New Zealand; <bold>Matthew C. Dulik, Jill B. Gaieski, Amanda C. Owings, Theodore G. Schurr, Miguel G. Vilar</bold>, University of Pennsylvania, Philadelphia, Pennsylvania, United States; <bold>Angela Hobbs, Himla Soodyall,</bold> National Health Laboratory Service, Johannesburg, South Africa; <bold>Asif Javed, Laxmi Parida, Daniel E. Platt, Ajay K. Royyuru</bold>, IBM, Yorktown Heights, New York, United States; <bold>Li Jin, Shilin Li,</bold> Fudan University, Shanghai, China; <bold>Matthew E. Kaplan, Nirav C. Merchant,</bold> University of Arizona, Tucson, Arizona, United States; <bold>R. John Mitchell,</bold> La Trobe University, Melbourne, Victoria, Australia; <bold>Lluis Quintana-Murci,</bold> Institut Pasteur, Paris, France; <bold>Colin Renfrew,</bold> University of Cambridge, Cambridge, United Kingdom; <bold>Daniela R. Lacerda, Fabrício R. Santos,</bold> Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; <bold>David F. Soria Hernanz, R. Spencer Wells,</bold> National Geographic Society, Washington, District of Columbia, United States; <bold>Pandikumar Swamikrishnan,</bold> IBM, Somers, New York, United States; <bold>Chris Tyler-Smith,</bold> The Wellcome Trust Sanger Institute, Hinxton, United Kingdom; <bold>Pedro Paulo Vieira,</bold> Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; <bold>Janet S. Ziegle,</bold> Applied Biosystems, Foster City, California, United States.</p></fn><fn id="FN4"><p id="P4"><bold>Author contributions</bold>:</p><p id="P5">P.B., W.H., and A.C. conceived and designed the project. P.B. designed and developed the DNA extraction, DNA library construction and hybridisation-based DNA-capture protocols (with assistance from J.T.). P.B., J.T., and W.H. generated and analysed the data. S.M.R., C.D., R.K., and M.B.v.d.H. contributed experimental steps and C.J.A., J.S., S.Y.W.H., J.K., and K.L. contributed analytical steps. G.B., R.G., S.F., V.D., M.v.O., L.Q., D.M.B., H.M., and K.W.A. provided ancient samples, contextual information, radiocarbon dating, and access to critical population data. P.B., W.H. and A.C. wrote the manuscript with input from C.J.A., J.S., S.Y.W.H., S.M.R., and J.K. All authors discussed the paper and gave comments.</p></fn></author-notes><pub-date pub-type="nihms-submitted"><day>2</day><month>4</month><year>2014</year></pub-date><pub-date pub-type="ppub"><year>2013</year></pub-date><pub-date pub-type="pmc-release"><day>08</day><month>4</month><year>2014</year></pub-date><volume>4</volume><fpage>1764</fpage><lpage>1764</lpage><pmc-comment>elocation-id from pubmed: 10.1038/ncomms2656</pmc-comment>
<abstract><p id="P6">Haplogroup (hg) H dominates present-day Western European mitochondrial (mt) DNA variability (>40%), yet was less common (~19%) amongst Early Neolithic farmers (~5450 BC) and virtually absent in Mesolithic hunter-gatherers. Here we investigate this major component of the maternal population history of modern Europeans and sequence 39 complete hg H mitochondrial genomes from ancient human remains. We then compare this ‘real-time’ genetic data with cultural changes taking place between the Early Neolithic (~5450 BC) and Bronze Age (~2200 BC) in Central Europe. Our results reveal that the current diversity and distribution of hg H were largely established by the Mid-Neolithic (~4000 BC), but with substantial genetic contributions from subsequent pan-European cultures such as the Bell Beakers expanding out of Iberia in the Late Neolithic (~2800 BC). Dated hg H genomes allow us to reconstruct the recent evolutionary history of hg H and reveal a mutation rate 45% higher than current estimates for human mitochondria.</p></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Pmc/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001E690 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Pmc/Corpus/biblio.hfd -nk 001E690 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= Pmc
|étape= Corpus
|type= RBID
|clé=
|texte=
}}
| This area was generated with Dilib version V0.6.33. |  |