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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">The complete genome of the crenarchaeon <italic>Sulfolobus solfataricus</italic> P2</title><author><name sortKey="She, Qunxin" sort="She, Qunxin" uniqKey="She Q" first="Qunxin" last="She">Qunxin She</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Microbial Genome Group, Institute of Molecular Biology, University of Copenhagen, Sølvgade 83H, DK-1307 Copenhagen, Denmark;</nlm:aff></affiliation></author><author><name sortKey="Singh, Rama K" sort="Singh, Rama K" uniqKey="Singh R" first="Rama K." last="Singh">Rama K. Singh</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">National Research Council of Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, NS, Canada B3H 3Z1;</nlm:aff></affiliation></author><author><name sortKey="Confalonieri, Fabrice" sort="Confalonieri, Fabrice" uniqKey="Confalonieri F" first="Fabrice" last="Confalonieri">Fabrice Confalonieri</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Université Paris-Sud, Institut de Génétique et Microbiologie, 15, Rue Georges Clemenceau, Bâtiment 400, FR-91405 Orsay Cedex, France;</nlm:aff></affiliation></author><author><name sortKey="Zivanovic, Yvan" sort="Zivanovic, Yvan" uniqKey="Zivanovic Y" first="Yvan" last="Zivanovic">Yvan Zivanovic</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Université Paris-Sud, Institut de Génétique et Microbiologie, 15, Rue Georges Clemenceau, Bâtiment 400, FR-91405 Orsay Cedex, France;</nlm:aff></affiliation></author><author><name sortKey="Allard, Ghislaine" sort="Allard, Ghislaine" uniqKey="Allard G" first="Ghislaine" last="Allard">Ghislaine Allard</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">University of Ottawa, Department of Biology, 30 Marie Curie, Ottawa, ON, Canada K1N 6N5;</nlm:aff></affiliation></author><author><name sortKey="Awayez, Mariana J" sort="Awayez, Mariana J" uniqKey="Awayez M" first="Mariana J." last="Awayez">Mariana J. Awayez</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Microbial Genome Group, Institute of Molecular Biology, University of Copenhagen, Sølvgade 83H, DK-1307 Copenhagen, Denmark;</nlm:aff></affiliation></author><author><name sortKey="Chan Weiher, Christina C Y" sort="Chan Weiher, Christina C Y" uniqKey="Chan Weiher C" first="Christina C.-Y." last="Chan-Weiher">Christina C.-Y. Chan-Weiher</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">University of Ottawa, Department of Biology, 30 Marie Curie, Ottawa, ON, Canada K1N 6N5;</nlm:aff></affiliation></author><author><name sortKey="Clausen, Ib Groth" sort="Clausen, Ib Groth" uniqKey="Clausen I" first="Ib Groth" last="Clausen">Ib Groth Clausen</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Novozymes, Novo Alle, DK-2880 Bagsværd, Denmark;</nlm:aff></affiliation></author><author><name sortKey="Curtis, Bruce A" sort="Curtis, Bruce A" uniqKey="Curtis B" first="Bruce A." last="Curtis">Bruce A. Curtis</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">National Research Council of Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, NS, Canada B3H 3Z1;</nlm:aff></affiliation></author><author><name sortKey="De Moors, Anick" sort="De Moors, Anick" uniqKey="De Moors A" first="Anick" last="De Moors">Anick De Moors</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">University of Ottawa, Department of Biology, 30 Marie Curie, Ottawa, ON, Canada K1N 6N5;</nlm:aff></affiliation></author><author><name sortKey="Erauso, Gael" sort="Erauso, Gael" uniqKey="Erauso G" first="Gael" last="Erauso">Gael Erauso</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Wageningen University, Laboratory of Microbiology, Hesselink van Suchtelenweg 4, NL-6703 CT, Wageningen, The Netherlands;</nlm:aff></affiliation></author><author><name sortKey="Fletcher, Cynthia" sort="Fletcher, Cynthia" uniqKey="Fletcher C" first="Cynthia" last="Fletcher">Cynthia Fletcher</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">National Research Council of Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, NS, Canada B3H 3Z1;</nlm:aff></affiliation></author><author><name sortKey="Gordon, Paul M K" sort="Gordon, Paul M K" uniqKey="Gordon P" first="Paul M. K." last="Gordon">Paul M. K. Gordon</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">National Research Council of Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, NS, Canada B3H 3Z1;</nlm:aff></affiliation></author><author><name sortKey="Heikamp De Jong, Ineke" sort="Heikamp De Jong, Ineke" uniqKey="Heikamp De Jong I" first="Ineke" last="Heikamp-De Jong">Ineke Heikamp-De Jong</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Wageningen University, Laboratory of Microbiology, Hesselink van Suchtelenweg 4, NL-6703 CT, Wageningen, The Netherlands;</nlm:aff></affiliation></author><author><name sortKey="Jeffries, Alex C" sort="Jeffries, Alex C" uniqKey="Jeffries A" first="Alex C." last="Jeffries">Alex C. Jeffries</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">National Research Council of Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, NS, Canada B3H 3Z1;</nlm:aff></affiliation></author><author><name sortKey="Kozera, Catherine J" sort="Kozera, Catherine J" uniqKey="Kozera C" first="Catherine J." last="Kozera">Catherine J. Kozera</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">National Research Council of Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, NS, Canada B3H 3Z1;</nlm:aff></affiliation></author><author><name sortKey="Medina, Nadine" sort="Medina, Nadine" uniqKey="Medina N" first="Nadine" last="Medina">Nadine Medina</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Université Paris-Sud, Institut de Génétique et Microbiologie, 15, Rue Georges Clemenceau, Bâtiment 400, FR-91405 Orsay Cedex, France;</nlm:aff></affiliation></author><author><name sortKey="Peng, Xu" sort="Peng, Xu" uniqKey="Peng X" first="Xu" last="Peng">Xu Peng</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Microbial Genome Group, Institute of Molecular Biology, University of Copenhagen, Sølvgade 83H, DK-1307 Copenhagen, Denmark;</nlm:aff></affiliation></author><author><name sortKey="Thi Ngoc, Hoa Phan" sort="Thi Ngoc, Hoa Phan" uniqKey="Thi Ngoc H" first="Hoa Phan" last="Thi-Ngoc">Hoa Phan Thi-Ngoc</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Microbial Genome Group, Institute of Molecular Biology, University of Copenhagen, Sølvgade 83H, DK-1307 Copenhagen, Denmark;</nlm:aff></affiliation></author><author><name sortKey="Redder, Peter" sort="Redder, Peter" uniqKey="Redder P" first="Peter" last="Redder">Peter Redder</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Microbial Genome Group, Institute of Molecular Biology, University of Copenhagen, Sølvgade 83H, DK-1307 Copenhagen, Denmark;</nlm:aff></affiliation></author><author><name sortKey="Schenk, Margaret E" sort="Schenk, Margaret E" uniqKey="Schenk M" first="Margaret E." last="Schenk">Margaret E. Schenk</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Dalhousie University, Department of Biochemistry, Sir Charles Tupper Medical Building, Halifax, NS, Canada B3H 4H7;</nlm:aff></affiliation></author><author><name sortKey="Theriault, Cynthia" sort="Theriault, Cynthia" uniqKey="Theriault C" first="Cynthia" last="Theriault">Cynthia Theriault</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">National Research Council of Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, NS, Canada B3H 3Z1;</nlm:aff></affiliation></author><author><name sortKey="Tolstrup, Niels" sort="Tolstrup, Niels" uniqKey="Tolstrup N" first="Niels" last="Tolstrup">Niels Tolstrup</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Novozymes, Novo Alle, DK-2880 Bagsværd, Denmark;</nlm:aff></affiliation></author><author><name sortKey="Charlebois, Robert L" sort="Charlebois, Robert L" uniqKey="Charlebois R" first="Robert L." last="Charlebois">Robert L. Charlebois</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">University of Ottawa, Department of Biology, 30 Marie Curie, Ottawa, ON, Canada K1N 6N5;</nlm:aff></affiliation></author><author><name sortKey="Doolittle, W Ford" sort="Doolittle, W Ford" uniqKey="Doolittle W" first="W. Ford" last="Doolittle">W. Ford Doolittle</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Dalhousie University, Department of Biochemistry, Sir Charles Tupper Medical Building, Halifax, NS, Canada B3H 4H7;</nlm:aff></affiliation></author><author><name sortKey="Duguet, Michel" sort="Duguet, Michel" uniqKey="Duguet M" first="Michel" last="Duguet">Michel Duguet</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Université Paris-Sud, Institut de Génétique et Microbiologie, 15, Rue Georges Clemenceau, Bâtiment 400, FR-91405 Orsay Cedex, France;</nlm:aff></affiliation></author><author><name sortKey="Gaasterland, Terry" sort="Gaasterland, Terry" uniqKey="Gaasterland T" first="Terry" last="Gaasterland">Terry Gaasterland</name><affiliation><nlm:aff wicri:cut="; and" id="N0x977aa00.0xa40ab10">The Rockefeller University, 1230 York Avenue, New York, NY 10021</nlm:aff></affiliation></author><author><name sortKey="Garrett, Roger A" sort="Garrett, Roger A" uniqKey="Garrett R" first="Roger A." last="Garrett">Roger A. Garrett</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Microbial Genome Group, Institute of Molecular Biology, University of Copenhagen, Sølvgade 83H, DK-1307 Copenhagen, Denmark;</nlm:aff></affiliation></author><author><name sortKey="Ragan, Mark A" sort="Ragan, Mark A" uniqKey="Ragan M" first="Mark A." last="Ragan">Mark A. Ragan</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">National Research Council of Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, NS, Canada B3H 3Z1;</nlm:aff></affiliation><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Institute for Molecular Bioscience, The University of Queensland, Brisbane, Qld 4072, Australia</nlm:aff></affiliation></author><author><name sortKey="Sensen, Christoph W" sort="Sensen, Christoph W" uniqKey="Sensen C" first="Christoph W." last="Sensen">Christoph W. Sensen</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">National Research Council of Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, NS, Canada B3H 3Z1;</nlm:aff></affiliation></author><author><name sortKey="Van Der Oost, John" sort="Van Der Oost, John" uniqKey="Van Der Oost J" first="John" last="Van Der Oost">John Van Der Oost</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Wageningen University, Laboratory of Microbiology, Hesselink van Suchtelenweg 4, NL-6703 CT, Wageningen, The Netherlands;</nlm:aff></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">11427726</idno><idno type="pmc">35428</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC35428</idno><idno type="RBID">PMC:35428</idno><idno type="doi">10.1073/pnas.141222098</idno><date when="2001">2001</date><idno type="wicri:Area/Pmc/Corpus">000A24</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000A24</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">The complete genome of the crenarchaeon <italic>Sulfolobus solfataricus</italic> P2</title><author><name sortKey="She, Qunxin" sort="She, Qunxin" uniqKey="She Q" first="Qunxin" last="She">Qunxin She</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Microbial Genome Group, Institute of Molecular Biology, University of Copenhagen, Sølvgade 83H, DK-1307 Copenhagen, Denmark;</nlm:aff></affiliation></author><author><name sortKey="Singh, Rama K" sort="Singh, Rama K" uniqKey="Singh R" first="Rama K." last="Singh">Rama K. Singh</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">National Research Council of Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, NS, Canada B3H 3Z1;</nlm:aff></affiliation></author><author><name sortKey="Confalonieri, Fabrice" sort="Confalonieri, Fabrice" uniqKey="Confalonieri F" first="Fabrice" last="Confalonieri">Fabrice Confalonieri</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Université Paris-Sud, Institut de Génétique et Microbiologie, 15, Rue Georges Clemenceau, Bâtiment 400, FR-91405 Orsay Cedex, France;</nlm:aff></affiliation></author><author><name sortKey="Zivanovic, Yvan" sort="Zivanovic, Yvan" uniqKey="Zivanovic Y" first="Yvan" last="Zivanovic">Yvan Zivanovic</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Université Paris-Sud, Institut de Génétique et Microbiologie, 15, Rue Georges Clemenceau, Bâtiment 400, FR-91405 Orsay Cedex, France;</nlm:aff></affiliation></author><author><name sortKey="Allard, Ghislaine" sort="Allard, Ghislaine" uniqKey="Allard G" first="Ghislaine" last="Allard">Ghislaine Allard</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">University of Ottawa, Department of Biology, 30 Marie Curie, Ottawa, ON, Canada K1N 6N5;</nlm:aff></affiliation></author><author><name sortKey="Awayez, Mariana J" sort="Awayez, Mariana J" uniqKey="Awayez M" first="Mariana J." last="Awayez">Mariana J. Awayez</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Microbial Genome Group, Institute of Molecular Biology, University of Copenhagen, Sølvgade 83H, DK-1307 Copenhagen, Denmark;</nlm:aff></affiliation></author><author><name sortKey="Chan Weiher, Christina C Y" sort="Chan Weiher, Christina C Y" uniqKey="Chan Weiher C" first="Christina C.-Y." last="Chan-Weiher">Christina C.-Y. Chan-Weiher</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">University of Ottawa, Department of Biology, 30 Marie Curie, Ottawa, ON, Canada K1N 6N5;</nlm:aff></affiliation></author><author><name sortKey="Clausen, Ib Groth" sort="Clausen, Ib Groth" uniqKey="Clausen I" first="Ib Groth" last="Clausen">Ib Groth Clausen</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Novozymes, Novo Alle, DK-2880 Bagsværd, Denmark;</nlm:aff></affiliation></author><author><name sortKey="Curtis, Bruce A" sort="Curtis, Bruce A" uniqKey="Curtis B" first="Bruce A." last="Curtis">Bruce A. Curtis</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">National Research Council of Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, NS, Canada B3H 3Z1;</nlm:aff></affiliation></author><author><name sortKey="De Moors, Anick" sort="De Moors, Anick" uniqKey="De Moors A" first="Anick" last="De Moors">Anick De Moors</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">University of Ottawa, Department of Biology, 30 Marie Curie, Ottawa, ON, Canada K1N 6N5;</nlm:aff></affiliation></author><author><name sortKey="Erauso, Gael" sort="Erauso, Gael" uniqKey="Erauso G" first="Gael" last="Erauso">Gael Erauso</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Wageningen University, Laboratory of Microbiology, Hesselink van Suchtelenweg 4, NL-6703 CT, Wageningen, The Netherlands;</nlm:aff></affiliation></author><author><name sortKey="Fletcher, Cynthia" sort="Fletcher, Cynthia" uniqKey="Fletcher C" first="Cynthia" last="Fletcher">Cynthia Fletcher</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">National Research Council of Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, NS, Canada B3H 3Z1;</nlm:aff></affiliation></author><author><name sortKey="Gordon, Paul M K" sort="Gordon, Paul M K" uniqKey="Gordon P" first="Paul M. K." last="Gordon">Paul M. K. Gordon</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">National Research Council of Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, NS, Canada B3H 3Z1;</nlm:aff></affiliation></author><author><name sortKey="Heikamp De Jong, Ineke" sort="Heikamp De Jong, Ineke" uniqKey="Heikamp De Jong I" first="Ineke" last="Heikamp-De Jong">Ineke Heikamp-De Jong</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Wageningen University, Laboratory of Microbiology, Hesselink van Suchtelenweg 4, NL-6703 CT, Wageningen, The Netherlands;</nlm:aff></affiliation></author><author><name sortKey="Jeffries, Alex C" sort="Jeffries, Alex C" uniqKey="Jeffries A" first="Alex C." last="Jeffries">Alex C. Jeffries</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">National Research Council of Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, NS, Canada B3H 3Z1;</nlm:aff></affiliation></author><author><name sortKey="Kozera, Catherine J" sort="Kozera, Catherine J" uniqKey="Kozera C" first="Catherine J." last="Kozera">Catherine J. Kozera</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">National Research Council of Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, NS, Canada B3H 3Z1;</nlm:aff></affiliation></author><author><name sortKey="Medina, Nadine" sort="Medina, Nadine" uniqKey="Medina N" first="Nadine" last="Medina">Nadine Medina</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Université Paris-Sud, Institut de Génétique et Microbiologie, 15, Rue Georges Clemenceau, Bâtiment 400, FR-91405 Orsay Cedex, France;</nlm:aff></affiliation></author><author><name sortKey="Peng, Xu" sort="Peng, Xu" uniqKey="Peng X" first="Xu" last="Peng">Xu Peng</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Microbial Genome Group, Institute of Molecular Biology, University of Copenhagen, Sølvgade 83H, DK-1307 Copenhagen, Denmark;</nlm:aff></affiliation></author><author><name sortKey="Thi Ngoc, Hoa Phan" sort="Thi Ngoc, Hoa Phan" uniqKey="Thi Ngoc H" first="Hoa Phan" last="Thi-Ngoc">Hoa Phan Thi-Ngoc</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Microbial Genome Group, Institute of Molecular Biology, University of Copenhagen, Sølvgade 83H, DK-1307 Copenhagen, Denmark;</nlm:aff></affiliation></author><author><name sortKey="Redder, Peter" sort="Redder, Peter" uniqKey="Redder P" first="Peter" last="Redder">Peter Redder</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Microbial Genome Group, Institute of Molecular Biology, University of Copenhagen, Sølvgade 83H, DK-1307 Copenhagen, Denmark;</nlm:aff></affiliation></author><author><name sortKey="Schenk, Margaret E" sort="Schenk, Margaret E" uniqKey="Schenk M" first="Margaret E." last="Schenk">Margaret E. Schenk</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Dalhousie University, Department of Biochemistry, Sir Charles Tupper Medical Building, Halifax, NS, Canada B3H 4H7;</nlm:aff></affiliation></author><author><name sortKey="Theriault, Cynthia" sort="Theriault, Cynthia" uniqKey="Theriault C" first="Cynthia" last="Theriault">Cynthia Theriault</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">National Research Council of Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, NS, Canada B3H 3Z1;</nlm:aff></affiliation></author><author><name sortKey="Tolstrup, Niels" sort="Tolstrup, Niels" uniqKey="Tolstrup N" first="Niels" last="Tolstrup">Niels Tolstrup</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Novozymes, Novo Alle, DK-2880 Bagsværd, Denmark;</nlm:aff></affiliation></author><author><name sortKey="Charlebois, Robert L" sort="Charlebois, Robert L" uniqKey="Charlebois R" first="Robert L." last="Charlebois">Robert L. Charlebois</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">University of Ottawa, Department of Biology, 30 Marie Curie, Ottawa, ON, Canada K1N 6N5;</nlm:aff></affiliation></author><author><name sortKey="Doolittle, W Ford" sort="Doolittle, W Ford" uniqKey="Doolittle W" first="W. Ford" last="Doolittle">W. Ford Doolittle</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Dalhousie University, Department of Biochemistry, Sir Charles Tupper Medical Building, Halifax, NS, Canada B3H 4H7;</nlm:aff></affiliation></author><author><name sortKey="Duguet, Michel" sort="Duguet, Michel" uniqKey="Duguet M" first="Michel" last="Duguet">Michel Duguet</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Université Paris-Sud, Institut de Génétique et Microbiologie, 15, Rue Georges Clemenceau, Bâtiment 400, FR-91405 Orsay Cedex, France;</nlm:aff></affiliation></author><author><name sortKey="Gaasterland, Terry" sort="Gaasterland, Terry" uniqKey="Gaasterland T" first="Terry" last="Gaasterland">Terry Gaasterland</name><affiliation><nlm:aff wicri:cut="; and" id="N0x977aa00.0xa40ab10">The Rockefeller University, 1230 York Avenue, New York, NY 10021</nlm:aff></affiliation></author><author><name sortKey="Garrett, Roger A" sort="Garrett, Roger A" uniqKey="Garrett R" first="Roger A." last="Garrett">Roger A. Garrett</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Microbial Genome Group, Institute of Molecular Biology, University of Copenhagen, Sølvgade 83H, DK-1307 Copenhagen, Denmark;</nlm:aff></affiliation></author><author><name sortKey="Ragan, Mark A" sort="Ragan, Mark A" uniqKey="Ragan M" first="Mark A." last="Ragan">Mark A. Ragan</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">National Research Council of Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, NS, Canada B3H 3Z1;</nlm:aff></affiliation><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Institute for Molecular Bioscience, The University of Queensland, Brisbane, Qld 4072, Australia</nlm:aff></affiliation></author><author><name sortKey="Sensen, Christoph W" sort="Sensen, Christoph W" uniqKey="Sensen C" first="Christoph W." last="Sensen">Christoph W. Sensen</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">National Research Council of Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, NS, Canada B3H 3Z1;</nlm:aff></affiliation></author><author><name sortKey="Van Der Oost, John" sort="Van Der Oost, John" uniqKey="Van Der Oost J" first="John" last="Van Der Oost">John Van Der Oost</name><affiliation><nlm:aff id="N0x977aa00.0xa40ab10">Wageningen University, Laboratory of Microbiology, Hesselink van Suchtelenweg 4, NL-6703 CT, Wageningen, The Netherlands;</nlm:aff></affiliation></author></analytic><series><title level="j">Proceedings of the National Academy of Sciences of the United States of America</title><idno type="ISSN">0027-8424</idno><idno type="eISSN">1091-6490</idno><imprint><date when="2001">2001</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>The genome of the crenarchaeon <italic>Sulfolobus solfataricus P2</italic> contains 2,992,245 bp on a single chromosome and encodes 2,977 proteins and many RNAs. One-third of the encoded proteins have no detectable homologs in other sequenced genomes. Moreover, 40% appear to be archaeal-specific, and only 12% and 2.3% are shared exclusively with bacteria and eukarya, respectively. The genome shows a high level of plasticity with 200 diverse insertion sequence elements, many putative nonautonomous mobile elements, and evidence of integrase-mediated insertion events. There are also long clusters of regularly spaced tandem repeats. Different transfer systems are used for the uptake of inorganic and organic solutes, and a wealth of intracellular and extracellular proteases, sugar, and sulfur metabolizing enzymes are encoded, as well as enzymes of the central metabolic pathways and motility proteins. The major metabolic electron carrier is not NADH as in bacteria and eukarya but probably ferredoxin. The essential components required for DNA replication, DNA repair and recombination, the cell cycle, transcriptional initiation and translation, but not DNA folding, show a strong eukaryal character with many archaeal-specific features. The results illustrate major differences between crenarchaea and euryarchaea, especially for their DNA replication mechanism and cell cycle processes and their translational apparatus.</p></div></front></TEI><pmc article-type="research-article"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Proc Natl Acad Sci U S A</journal-id><journal-id journal-id-type="publisher-id">PNAS</journal-id><journal-title>Proceedings of the National Academy of Sciences of the United States of America</journal-title><issn pub-type="ppub">0027-8424</issn><issn pub-type="epub">1091-6490</issn><publisher><publisher-name>The National Academy of Sciences</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">11427726</article-id><article-id pub-id-type="pmc">35428</article-id><article-id pub-id-type="publisher-id">141222098</article-id><article-id pub-id-type="publisher-id">2220</article-id><article-id pub-id-type="doi">10.1073/pnas.141222098</article-id><article-categories><subj-group subj-group-type="heading"><subject>Biological Sciences</subject><subj-group><subject>Cell Biology</subject></subj-group></subj-group></article-categories><title-group><article-title>The complete genome of the crenarchaeon <italic>Sulfolobus solfataricus</italic> P2</article-title></title-group><contrib-group><contrib contrib-type="author"><name><surname>She</surname><given-names>Qunxin</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">a</xref><xref ref-type="author-notes" rid="FNb">b</xref></contrib><contrib contrib-type="author"><name><surname>Singh</surname><given-names>Rama K.</given-names></name><xref ref-type="author-notes" rid="FNb">b</xref><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">c</xref></contrib><contrib contrib-type="author"><name><surname>Confalonieri</surname><given-names>Fabrice</given-names></name><xref ref-type="author-notes" rid="FNb">b</xref><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">d</xref></contrib><contrib contrib-type="author"><name><surname>Zivanovic</surname><given-names>Yvan</given-names></name><xref ref-type="author-notes" rid="FNb">b</xref><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">d</xref></contrib><contrib contrib-type="author"><name><surname>Allard</surname><given-names>Ghislaine</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">e</xref></contrib><contrib contrib-type="author"><name><surname>Awayez</surname><given-names>Mariana J.</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">a</xref></contrib><contrib contrib-type="author"><name><surname>Chan-Weiher</surname><given-names>Christina C.-Y.</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">e</xref></contrib><contrib contrib-type="author"><name><surname>Clausen</surname><given-names>Ib Groth</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">f</xref></contrib><contrib contrib-type="author"><name><surname>Curtis</surname><given-names>Bruce A.</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">c</xref></contrib><contrib contrib-type="author"><name><surname>De Moors</surname><given-names>Anick</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">e</xref></contrib><contrib contrib-type="author"><name><surname>Erauso</surname><given-names>Gael</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">g</xref></contrib><contrib contrib-type="author"><name><surname>Fletcher</surname><given-names>Cynthia</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">c</xref></contrib><contrib contrib-type="author"><name><surname>Gordon</surname><given-names>Paul M. K.</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">c</xref></contrib><contrib contrib-type="author"><name><surname>Heikamp-de Jong</surname><given-names>Ineke</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">g</xref></contrib><contrib contrib-type="author"><name><surname>Jeffries</surname><given-names>Alex C.</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">c</xref></contrib><contrib contrib-type="author"><name><surname>Kozera</surname><given-names>Catherine J.</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">c</xref></contrib><contrib contrib-type="author"><name><surname>Medina</surname><given-names>Nadine</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">d</xref></contrib><contrib contrib-type="author"><name><surname>Peng</surname><given-names>Xu</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">a</xref></contrib><contrib contrib-type="author"><name><surname>Thi-Ngoc</surname><given-names>Hoa Phan</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">a</xref></contrib><contrib contrib-type="author"><name><surname>Redder</surname><given-names>Peter</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">a</xref></contrib><contrib contrib-type="author"><name><surname>Schenk</surname><given-names>Margaret E.</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">h</xref></contrib><contrib contrib-type="author"><name><surname>Theriault</surname><given-names>Cynthia</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">c</xref></contrib><contrib contrib-type="author"><name><surname>Tolstrup</surname><given-names>Niels</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">f</xref></contrib><contrib contrib-type="author"><name><surname>Charlebois</surname><given-names>Robert L.</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">e</xref></contrib><contrib contrib-type="author"><name><surname>Doolittle</surname><given-names>W. Ford</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">h</xref></contrib><contrib contrib-type="author"><name><surname>Duguet</surname><given-names>Michel</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">d</xref></contrib><contrib contrib-type="author"><name><surname>Gaasterland</surname><given-names>Terry</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">i</xref></contrib><contrib contrib-type="author"><name><surname>Garrett</surname><given-names>Roger A.</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">a</xref><xref ref-type="author-notes" rid="FNj">j</xref></contrib><contrib contrib-type="author"><name><surname>Ragan</surname><given-names>Mark A.</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">c</xref><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">k</xref></contrib><contrib contrib-type="author"><name><surname>Sensen</surname><given-names>Christoph W.</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">c</xref><xref ref-type="author-notes" rid="FNl">l</xref></contrib><contrib contrib-type="author"><name><surname>Van der Oost</surname><given-names>John</given-names></name><xref ref-type="aff" rid="N0x977aa00.0xa40ab10">g</xref></contrib></contrib-group><aff id="N0x977aa00.0xa40ab10"><label>a</label>Microbial Genome Group, Institute of Molecular Biology, University of Copenhagen, Sølvgade 83H, DK-1307 Copenhagen, Denmark;<label>c</label>National Research Council of Canada, Institute for Marine Biosciences, 1411 Oxford Street, Halifax, NS, Canada B3H 3Z1;<label>d</label>Université Paris-Sud, Institut de Génétique et Microbiologie, 15, Rue Georges Clemenceau, Bâtiment 400, FR-91405 Orsay Cedex, France;<label>e</label>University of Ottawa, Department of Biology, 30 Marie Curie, Ottawa, ON, Canada K1N 6N5;<label>f</label>Novozymes, Novo Alle, DK-2880 Bagsværd, Denmark;<label>g</label>Wageningen University, Laboratory of Microbiology, Hesselink van Suchtelenweg 4, NL-6703 CT, Wageningen, The Netherlands;<label>h</label>Dalhousie University, Department of Biochemistry, Sir Charles Tupper Medical Building, Halifax, NS, Canada B3H 4H7;<label>i</label>The Rockefeller University, 1230 York Avenue, New York, NY 10021; and<label>k</label>Institute for Molecular Bioscience, The University of Queensland, Brisbane, Qld 4072, Australia</aff><author-notes><fn id="FNb"><label>b</label><p>Q.S., R.K.S., F.C., and Y.Z. contributed equally to this work.</p></fn><fn id="FNj"><label>j</label><p>To whom reprint requests should be addressed. E-mail: <email>garrett@mermaid.molbio.ku.dk</email>.</p></fn><fn id="FNl"><label>l</label><p>Present address: University of Calgary, Department of Biochemistry and Molecular Biology, 3330 Hospital Drive N.W., Calgary, AB, Canada T2N 4N1.</p></fn><fn><p>Communicated by Carl R. Woese, University of Illinois at Urbana–Champaign, Urbana, IL</p></fn></author-notes><pub-date pub-type="ppub"><day>3</day><month>7</month><year>2001</year></pub-date><pub-date pub-type="epub"><day>26</day><month>6</month><year>2001</year></pub-date><volume>98</volume><issue>14</issue><fpage>7835</fpage><lpage>7840</lpage><history><date date-type="received"><day>15</day><month>2</month><year>2001</year></date><date date-type="accepted"><day>4</day><month>5</month><year>2001</year></date></history><copyright-statement>Copyright © 2001, The National Academy of Sciences</copyright-statement><copyright-year>2001</copyright-year><abstract><p>The genome of the crenarchaeon <italic>Sulfolobus solfataricus P2</italic> contains 2,992,245 bp on a single chromosome and encodes 2,977 proteins and many RNAs. One-third of the encoded proteins have no detectable homologs in other sequenced genomes. Moreover, 40% appear to be archaeal-specific, and only 12% and 2.3% are shared exclusively with bacteria and eukarya, respectively. The genome shows a high level of plasticity with 200 diverse insertion sequence elements, many putative nonautonomous mobile elements, and evidence of integrase-mediated insertion events. There are also long clusters of regularly spaced tandem repeats. Different transfer systems are used for the uptake of inorganic and organic solutes, and a wealth of intracellular and extracellular proteases, sugar, and sulfur metabolizing enzymes are encoded, as well as enzymes of the central metabolic pathways and motility proteins. The major metabolic electron carrier is not NADH as in bacteria and eukarya but probably ferredoxin. The essential components required for DNA replication, DNA repair and recombination, the cell cycle, transcriptional initiation and translation, but not DNA folding, show a strong eukaryal character with many archaeal-specific features. The results illustrate major differences between crenarchaea and euryarchaea, especially for their DNA replication mechanism and cell cycle processes and their translational apparatus.</p></abstract></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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