Cell vesiculation and immunopathology : implications in cerebral malaria
Identifieur interne : 001F59 ( PascalFrancis/Curation ); précédent : 001F58; suivant : 001F60Cell vesiculation and immunopathology : implications in cerebral malaria
Auteurs : Nicolas Coltel [France] ; Valéry Combes [France, Australie] ; Samuel C. Wassmer [Malawi] ; Giovanna Chimini [France] ; Georges E. Grau [France, Australie]Source :
- Microbes and infection [ 1286-4579 ] ; 2006.
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- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Microparticles are plasma membrane fragments that are generated and released under physiological conditions. They are also released when tissue and/or systemic homeostasis is disrupted. These microparticles display different physiological features of the cells from which they originate. They are detected in some pathological conditions, but rarely suspected of participating in the disease's pathogenesis. In the present review, we summarise data about the production of the microparticles, their biological significance and potential role during microorganism-driven processes, especially in cerebral malaria.
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<front><div type="abstract" xml:lang="en">Microparticles are plasma membrane fragments that are generated and released under physiological conditions. They are also released when tissue and/or systemic homeostasis is disrupted. These microparticles display different physiological features of the cells from which they originate. They are detected in some pathological conditions, but rarely suspected of participating in the disease's pathogenesis. In the present review, we summarise data about the production of the microparticles, their biological significance and potential role during microorganism-driven processes, especially in cerebral malaria.</div>
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