Atypical mood stabilizers: a 'typical' role for atypical antipsychotics
Identifieur interne : 004937 ( PascalFrancis/Corpus ); précédent : 004936; suivant : 004938Atypical mood stabilizers: a 'typical' role for atypical antipsychotics
Auteurs : G. S. Malhi ; M. Berk ; M. Bourin ; B. Ivanovski ; S. Dodd ; J. Lagopoulos ; P. B. MitchellSource :
- Acta psychiatrica scandinavica. Supplementum [ 0065-1591 ] ; 2005.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
Abstract
Objective: To assess the potential role of atypical antipsychotics as mood stabilizers. Method: A MedLine, PsychLIT, PubMed, and EMBASE literature search of papers published up to December 2004 was conducted using the names of atypical antipsychotics and a number of key terms relevant to bipolar disorder. Additional articles were retrieved by scrutinizing the bibliographies of review papers and literature known to the authors. Data pertinent to the objective was reviewed according to the various phases of bipolar disorder. Results: The data is most substantive for the use of atypical antipsychotics in mania, to the extent that an argument for a class effect of significant efficacy can be made. This does not extend to bipolar depression, however, good data is now emerging for some agents and will need to be considered for each individual agent as it accumulates. As regards mixed states and rapid cycling the evidence is thus far sparse and too few maintenance studies have been conducted to make any firm assertions. However, with respect to long-term therapy the atypical antipsychotics do have clinically significant side-effects of which clinicians need to be aware. Conclusion: Based on the evidence thus far it is perhaps premature to describe the atypical antipsychotics as mood stabilizers. Individual agents may eventually be able to claim this label, however, much further research is needed especially with respect to maintenance and relapse prevention.
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Pour connaître la documentation sur le format Inist Standard.
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Format Inist (serveur)
NO : | PASCAL 05-0265817 INIST |
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ET : | Atypical mood stabilizers: a 'typical' role for atypical antipsychotics |
AU : | MALHI (G. S.); BERK (M.); BOURIN (M.); IVANOVSKI (B.); DODD (S.); LAGOPOULOS (J.); MITCHELL (P. B.); MALHI (G. S.); MITCHELL (P. B.); BERK (M.); GOODWIN (G. M.) |
AF : | Mood Disorders Unit, Black Dog Institute, Prince of Wales Hospital/Sydney/Australie (1 aut., 4 aut., 6 aut., 7 aut.); School of Psychiatry, University of New South Wales/Sydney/Australie (1 aut., 4 aut., 6 aut., 7 aut.); Mayne Clinical Research Imaging Centre, Prince of Wales Medical Research Institute/Sydney/Australie (1 aut., 6 aut.); Department of Clinical and Biomedical Sciences, The University of Melbourne/Melbourne/Australie (2 aut., 5 aut.); Community and Mental Health, Barwon Health/Geelong/Australie (2 aut., 5 aut.); Drygen Research Centre/Parkville/Australie (2 aut.); Faculté de Médecine, Université de Nantes/Nantes/France (3 aut.); Mood Disorders Unit, Black Dog Institute, Prince of Wales Hospital, University of New South Wales/Sydney, NSW/Australie (1 aut., 2 aut.); School of Psychiatry, University of New South Wales/Sydney, NSW/Etats-Unis (1 aut., 2 aut.); Department of Clinical and Biomedical Sciences, The University of Melbourne/Melbourne/Australie (3 aut.); Community and Mental Health, Barwon Health/Geelong/Australie (3 aut.); Orygen Research Centre/Parkville/Australie (3 aut.); University Department of Psychiatry, Warnford Hospital/Oxford/Royaume-Uni (4 aut.) |
DT : | Publication en série; Niveau analytique |
SO : | Acta psychiatrica scandinavica. Supplementum; ISSN 0065-1591; Coden ASSUA6; Royaume-Uni; Da. 2005; Vol. 111; No. 426; Pp. 29-38; Bibl. 95 ref. |
LA : | Anglais |
EA : | Objective: To assess the potential role of atypical antipsychotics as mood stabilizers. Method: A MedLine, PsychLIT, PubMed, and EMBASE literature search of papers published up to December 2004 was conducted using the names of atypical antipsychotics and a number of key terms relevant to bipolar disorder. Additional articles were retrieved by scrutinizing the bibliographies of review papers and literature known to the authors. Data pertinent to the objective was reviewed according to the various phases of bipolar disorder. Results: The data is most substantive for the use of atypical antipsychotics in mania, to the extent that an argument for a class effect of significant efficacy can be made. This does not extend to bipolar depression, however, good data is now emerging for some agents and will need to be considered for each individual agent as it accumulates. As regards mixed states and rapid cycling the evidence is thus far sparse and too few maintenance studies have been conducted to make any firm assertions. However, with respect to long-term therapy the atypical antipsychotics do have clinically significant side-effects of which clinicians need to be aware. Conclusion: Based on the evidence thus far it is perhaps premature to describe the atypical antipsychotics as mood stabilizers. Individual agents may eventually be able to claim this label, however, much further research is needed especially with respect to maintenance and relapse prevention. |
CC : | 002B02B02 |
FD : | Normothymique; Psychotrope; Chimiothérapie; Antipsychotique atypique; Traitement; Trouble bipolaire; Efficacité traitement; Article synthèse; Homme |
FG : | Trouble humeur |
ED : | Mood stabilizer; Psychotropic; Chemotherapy; Atypical antipsychotic; Treatment; Bipolar disorder; Treatment efficiency; Review; Human |
EG : | Mood disorder |
SD : | Estabilizador humor; Psicotropo; Quimioterapia; Antipsicótico atípico; Tratamiento; Trastorno bipolar; Eficacia tratamiento; Artículo síntesis; Hombre |
LO : | INIST-3204B.354000125344190040 |
ID : | 05-0265817 |
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Pascal:05-0265817Le document en format XML
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<front><div type="abstract" xml:lang="en">Objective: To assess the potential role of atypical antipsychotics as mood stabilizers. Method: A MedLine, PsychLIT, PubMed, and EMBASE literature search of papers published up to December 2004 was conducted using the names of atypical antipsychotics and a number of key terms relevant to bipolar disorder. Additional articles were retrieved by scrutinizing the bibliographies of review papers and literature known to the authors. Data pertinent to the objective was reviewed according to the various phases of bipolar disorder. Results: The data is most substantive for the use of atypical antipsychotics in mania, to the extent that an argument for a class effect of significant efficacy can be made. This does not extend to bipolar depression, however, good data is now emerging for some agents and will need to be considered for each individual agent as it accumulates. As regards mixed states and rapid cycling the evidence is thus far sparse and too few maintenance studies have been conducted to make any firm assertions. However, with respect to long-term therapy the atypical antipsychotics do have clinically significant side-effects of which clinicians need to be aware. Conclusion: Based on the evidence thus far it is perhaps premature to describe the atypical antipsychotics as mood stabilizers. Individual agents may eventually be able to claim this label, however, much further research is needed especially with respect to maintenance and relapse prevention.</div>
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<fA15 i1="01"><s1>Mood Disorders Unit, Black Dog Institute, Prince of Wales Hospital, University of New South Wales</s1>
<s2>Sydney, NSW</s2>
<s3>AUS</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
</fA15>
<fA15 i1="02"><s1>School of Psychiatry, University of New South Wales</s1>
<s2>Sydney, NSW</s2>
<s3>USA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
</fA15>
<fA15 i1="03"><s1>Department of Clinical and Biomedical Sciences, The University of Melbourne</s1>
<s2>Melbourne</s2>
<s3>AUS</s3>
<sZ>3 aut.</sZ>
</fA15>
<fA15 i1="04"><s1>Community and Mental Health, Barwon Health</s1>
<s2>Geelong</s2>
<s3>AUS</s3>
<sZ>3 aut.</sZ>
</fA15>
<fA15 i1="05"><s1>Orygen Research Centre</s1>
<s2>Parkville</s2>
<s3>AUS</s3>
<sZ>3 aut.</sZ>
</fA15>
<fA15 i1="06"><s1>University Department of Psychiatry, Warnford Hospital</s1>
<s2>Oxford</s2>
<s3>GBR</s3>
<sZ>4 aut.</sZ>
</fA15>
<fA20><s1>29-38</s1>
</fA20>
<fA21><s1>2005</s1>
</fA21>
<fA23 i1="01"><s0>ENG</s0>
</fA23>
<fA43 i1="01"><s1>INIST</s1>
<s2>3204B</s2>
<s5>354000125344190040</s5>
</fA43>
<fA44><s0>0000</s0>
<s1>© 2005 INIST-CNRS. All rights reserved.</s1>
</fA44>
<fA45><s0>95 ref.</s0>
</fA45>
<fA47 i1="01" i2="1"><s0>05-0265817</s0>
</fA47>
<fA60><s1>P</s1>
</fA60>
<fA61><s0>A</s0>
</fA61>
<fA64 i1="01" i2="1"><s0>Acta psychiatrica scandinavica. Supplementum</s0>
</fA64>
<fA66 i1="01"><s0>GBR</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>Objective: To assess the potential role of atypical antipsychotics as mood stabilizers. Method: A MedLine, PsychLIT, PubMed, and EMBASE literature search of papers published up to December 2004 was conducted using the names of atypical antipsychotics and a number of key terms relevant to bipolar disorder. Additional articles were retrieved by scrutinizing the bibliographies of review papers and literature known to the authors. Data pertinent to the objective was reviewed according to the various phases of bipolar disorder. Results: The data is most substantive for the use of atypical antipsychotics in mania, to the extent that an argument for a class effect of significant efficacy can be made. This does not extend to bipolar depression, however, good data is now emerging for some agents and will need to be considered for each individual agent as it accumulates. As regards mixed states and rapid cycling the evidence is thus far sparse and too few maintenance studies have been conducted to make any firm assertions. However, with respect to long-term therapy the atypical antipsychotics do have clinically significant side-effects of which clinicians need to be aware. Conclusion: Based on the evidence thus far it is perhaps premature to describe the atypical antipsychotics as mood stabilizers. Individual agents may eventually be able to claim this label, however, much further research is needed especially with respect to maintenance and relapse prevention.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B02B02</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Normothymique</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Mood stabilizer</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Estabilizador humor</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Psychotrope</s0>
<s2>FX</s2>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Psychotropic</s0>
<s2>FX</s2>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Psicotropo</s0>
<s2>FX</s2>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Chimiothérapie</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Chemotherapy</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Quimioterapia</s0>
<s5>03</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Antipsychotique atypique</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Atypical antipsychotic</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Antipsicótico atípico</s0>
<s5>04</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Traitement</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="ENG"><s0>Treatment</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Tratamiento</s0>
<s5>05</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Trouble bipolaire</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="ENG"><s0>Bipolar disorder</s0>
<s5>06</s5>
</fC03>
<fC03 i1="06" i2="X" l="SPA"><s0>Trastorno bipolar</s0>
<s5>06</s5>
</fC03>
<fC03 i1="07" i2="X" l="FRE"><s0>Efficacité traitement</s0>
<s5>07</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>Treatment efficiency</s0>
<s5>07</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Eficacia tratamiento</s0>
<s5>07</s5>
</fC03>
<fC03 i1="08" i2="X" l="FRE"><s0>Article synthèse</s0>
<s5>08</s5>
</fC03>
<fC03 i1="08" i2="X" l="ENG"><s0>Review</s0>
<s5>08</s5>
</fC03>
<fC03 i1="08" i2="X" l="SPA"><s0>Artículo síntesis</s0>
<s5>08</s5>
</fC03>
<fC03 i1="09" i2="X" l="FRE"><s0>Homme</s0>
<s5>18</s5>
</fC03>
<fC03 i1="09" i2="X" l="ENG"><s0>Human</s0>
<s5>18</s5>
</fC03>
<fC03 i1="09" i2="X" l="SPA"><s0>Hombre</s0>
<s5>18</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Trouble humeur</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Mood disorder</s0>
<s5>37</s5>
</fC07>
<fC07 i1="01" i2="X" l="SPA"><s0>Trastorno humor</s0>
<s5>37</s5>
</fC07>
<fN21><s1>185</s1>
</fN21>
</pA>
</standard>
<server><NO>PASCAL 05-0265817 INIST</NO>
<ET>Atypical mood stabilizers: a 'typical' role for atypical antipsychotics</ET>
<AU>MALHI (G. S.); BERK (M.); BOURIN (M.); IVANOVSKI (B.); DODD (S.); LAGOPOULOS (J.); MITCHELL (P. B.); MALHI (G. S.); MITCHELL (P. B.); BERK (M.); GOODWIN (G. M.)</AU>
<AF>Mood Disorders Unit, Black Dog Institute, Prince of Wales Hospital/Sydney/Australie (1 aut., 4 aut., 6 aut., 7 aut.); School of Psychiatry, University of New South Wales/Sydney/Australie (1 aut., 4 aut., 6 aut., 7 aut.); Mayne Clinical Research Imaging Centre, Prince of Wales Medical Research Institute/Sydney/Australie (1 aut., 6 aut.); Department of Clinical and Biomedical Sciences, The University of Melbourne/Melbourne/Australie (2 aut., 5 aut.); Community and Mental Health, Barwon Health/Geelong/Australie (2 aut., 5 aut.); Drygen Research Centre/Parkville/Australie (2 aut.); Faculté de Médecine, Université de Nantes/Nantes/France (3 aut.); Mood Disorders Unit, Black Dog Institute, Prince of Wales Hospital, University of New South Wales/Sydney, NSW/Australie (1 aut., 2 aut.); School of Psychiatry, University of New South Wales/Sydney, NSW/Etats-Unis (1 aut., 2 aut.); Department of Clinical and Biomedical Sciences, The University of Melbourne/Melbourne/Australie (3 aut.); Community and Mental Health, Barwon Health/Geelong/Australie (3 aut.); Orygen Research Centre/Parkville/Australie (3 aut.); University Department of Psychiatry, Warnford Hospital/Oxford/Royaume-Uni (4 aut.)</AF>
<DT>Publication en série; Niveau analytique</DT>
<SO>Acta psychiatrica scandinavica. Supplementum; ISSN 0065-1591; Coden ASSUA6; Royaume-Uni; Da. 2005; Vol. 111; No. 426; Pp. 29-38; Bibl. 95 ref.</SO>
<LA>Anglais</LA>
<EA>Objective: To assess the potential role of atypical antipsychotics as mood stabilizers. Method: A MedLine, PsychLIT, PubMed, and EMBASE literature search of papers published up to December 2004 was conducted using the names of atypical antipsychotics and a number of key terms relevant to bipolar disorder. Additional articles were retrieved by scrutinizing the bibliographies of review papers and literature known to the authors. Data pertinent to the objective was reviewed according to the various phases of bipolar disorder. Results: The data is most substantive for the use of atypical antipsychotics in mania, to the extent that an argument for a class effect of significant efficacy can be made. This does not extend to bipolar depression, however, good data is now emerging for some agents and will need to be considered for each individual agent as it accumulates. As regards mixed states and rapid cycling the evidence is thus far sparse and too few maintenance studies have been conducted to make any firm assertions. However, with respect to long-term therapy the atypical antipsychotics do have clinically significant side-effects of which clinicians need to be aware. Conclusion: Based on the evidence thus far it is perhaps premature to describe the atypical antipsychotics as mood stabilizers. Individual agents may eventually be able to claim this label, however, much further research is needed especially with respect to maintenance and relapse prevention.</EA>
<CC>002B02B02</CC>
<FD>Normothymique; Psychotrope; Chimiothérapie; Antipsychotique atypique; Traitement; Trouble bipolaire; Efficacité traitement; Article synthèse; Homme</FD>
<FG>Trouble humeur</FG>
<ED>Mood stabilizer; Psychotropic; Chemotherapy; Atypical antipsychotic; Treatment; Bipolar disorder; Treatment efficiency; Review; Human</ED>
<EG>Mood disorder</EG>
<SD>Estabilizador humor; Psicotropo; Quimioterapia; Antipsicótico atípico; Tratamiento; Trastorno bipolar; Eficacia tratamiento; Artículo síntesis; Hombre</SD>
<LO>INIST-3204B.354000125344190040</LO>
<ID>05-0265817</ID>
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