AustralieFrV1, PascalFrancis, Corpus, bibRecord, 004218

Oral fluid testing for cannabis : On-site OraLine®. IV s.a.t. device versus GC/MS

Identifieur interne : 004218 ( PascalFrancis/Corpus ); précédent : 004217; suivant : 004219

Oral fluid testing for cannabis : On-site OraLine®. IV s.a.t. device versus GC/MS

Auteurs : Vincent Cirimele ; Marion Villain ; Patrick Mura ; Marc Bernard ; Pascal Kintz

Source :

Forensic science international [ 0379-0738 ] ; 2006.

RBID : Pascal:06-0403689

Descripteurs français

Pascal (Inist)
- Chromatographie phase gazeuse, Liquide biologique, Salive, Spectrométrie masse, Dépistage, Cannabis, Site, Dispositif médical, Etude comparative, Essai, Exploration, Détection, Diagnostic, Technique, Médecine légale, Aspect médicolégal, Police scientifique, Substance toxicomanogène.

English descriptors

KwdEn :
- Biological fluid, Cannabis, Comparative study, Detection, Diagnosis, Drug of abuse, Exploration, Forensic aspect, Forensic science, Gas chromatography, Legal medicine, Mass spectrometry, Medical device, Medical screening, Saliva, Site, Technique, Test.

Abstract

Saliva or "oral fluid" has been presented as an alternative matrix to document drug use. The non-invasive collection of a saliva sample, which is relatively easy to perform and can be achieved under close supervision, is one of the most important benefits in a driving under the influence situation. Moreover, the presence of A9-tetrahydrocannabinol (THC) in oral fluid is a better indication of recent use than when 11-nor-Δ⁹-tetrahydrocannabinol-9-carboxylic acid (THC-COOH) is detected in urine, so there is a higher probability that the subject is experiencing pharmacological effects at the time of sampling. In the first part of the study, 27 drug addicts were tested for the presence of THC using the OraLine® IV s.a.t. device to establish the potential of this new on-site DOA detection technique. In parallel, oral fluid was collected with the Intercept® DOA Oral Specimen Collection device and tested for THC by gas chromatography mass spectrometry (GC/MS) after methylation for THC (limit of quantification: 1 ng/mL). The OraLine® device correctly identified nine saliva specimens positive for cannabis with THC concentrations ranging from 3 to 265 ng/mL, but remained negative in four other samples where low THC concentrations were detected by GC/MS (1-13 ng/mL). One false positive was noted. Secondly, two male subjects were screened in saliva using the OraLine® and Intercept® devices after consumption of a single cannabis cigarette containing 25 mg of THC. Saliva was first tested with the OraLine® device and then collected with the Intercept® device for GC/MS confirmation. In one subject, the OraLine® on-site test was positive for THC for 2 h following drug intake with THC concentrations decreasing from 196 to 16 ng/mL, while the test remained positive for 1.5 h for the second subject (THC concentrations ranging from 199 to 11 ng/mL). These preliminary results obtained with the OraLine® IV s.a.t. device indicate more encouraging data for the detection of THC using on-site tests than previous evaluations.

Notice en format standard (ISO 2709)

Pour connaître la documentation sur le format Inist Standard.

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C01	`01`		`ENG`	@0 Saliva or "oral fluid" has been presented as an alternative matrix to document drug use. The non-invasive collection of a saliva sample, which is relatively easy to perform and can be achieved under close supervision, is one of the most important benefits in a driving under the influence situation. Moreover, the presence of A9-tetrahydrocannabinol (THC) in oral fluid is a better indication of recent use than when 11-nor-Δ⁹-tetrahydrocannabinol-9-carboxylic acid (THC-COOH) is detected in urine, so there is a higher probability that the subject is experiencing pharmacological effects at the time of sampling. In the first part of the study, 27 drug addicts were tested for the presence of THC using the OraLine® IV s.a.t. device to establish the potential of this new on-site DOA detection technique. In parallel, oral fluid was collected with the Intercept® DOA Oral Specimen Collection device and tested for THC by gas chromatography mass spectrometry (GC/MS) after methylation for THC (limit of quantification: 1 ng/mL). The OraLine® device correctly identified nine saliva specimens positive for cannabis with THC concentrations ranging from 3 to 265 ng/mL, but remained negative in four other samples where low THC concentrations were detected by GC/MS (1-13 ng/mL). One false positive was noted. Secondly, two male subjects were screened in saliva using the OraLine® and Intercept® devices after consumption of a single cannabis cigarette containing 25 mg of THC. Saliva was first tested with the OraLine® device and then collected with the Intercept® device for GC/MS confirmation. In one subject, the OraLine® on-site test was positive for THC for 2 h following drug intake with THC concentrations decreasing from 196 to 16 ng/mL, while the test remained positive for 1.5 h for the second subject (THC concentrations ranging from 199 to 11 ng/mL). These preliminary results obtained with the OraLine® IV s.a.t. device indicate more encouraging data for the detection of THC using on-site tests than previous evaluations.
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Format Inist (serveur)

NO :	PASCAL 06-0403689 INIST
ET :	Oral fluid testing for cannabis : On-site OraLine®. IV s.a.t. device versus GC/MS
AU :	CIRIMELE (Vincent); VILLAIN (Marion); MURA (Patrick); BERNARD (Marc); KINTZ (Pascal); CHUNG (Heesun); DRUMMER (Olaf H.)
AF :	Laboratoire ChemTox, 3, rue Grüninger/67400 Illkirch/France (1 aut., 2 aut., 5 aut.); Laboratoire de biochimie/Poitiers/France (3 aut.); Urgences Médico-judiciaires/Compiègne/France (4 aut.); National Institute of Scientific Investigation, 331-1 Shinwol-7 dong, Yancheon-gu/Seoul 158-707/Corée, République de (1 aut.); Department of Forensic Medicine, Victorian Institute of Forensic Medicine, 57-83 Kavanagh Street/Southbank 3006, Victoria/Australie (2 aut.)
DT :	Publication en série; Congrès; Niveau analytique
SO :	Forensic science international; ISSN 0379-0738; Coden FSINDR; Irlande; Da. 2006; Vol. 161; No. 2-3; Pp. 180-184; Bibl. 16 ref.
LA :	Anglais
EA :	Saliva or "oral fluid" has been presented as an alternative matrix to document drug use. The non-invasive collection of a saliva sample, which is relatively easy to perform and can be achieved under close supervision, is one of the most important benefits in a driving under the influence situation. Moreover, the presence of A9-tetrahydrocannabinol (THC) in oral fluid is a better indication of recent use than when 11-nor-Δ⁹-tetrahydrocannabinol-9-ca rboxylic acid (THC-COOH) is detected in urine, so there is a higher probability that the subject is experiencing pharmacological effects at the time of sampling. In the first part of the study, 27 drug addicts were tested for the presence of THC using the OraLine® IV s.a.t. device to establish the potential of this new on-site DOA detection technique. In parallel, oral fluid was collected with the Intercept® DOA Oral Specimen Collection device and tested for THC by gas chromatography mass spectrometry (GC/MS) after methylation for THC (limit of quantification: 1 ng/mL). The OraLine® device correctly identified nine saliva specimens positive for cannabis with THC concentrations ranging from 3 to 265 ng/mL, but remained negative in four other samples where low THC concentrations were detected by GC/MS (1-13 ng/mL). One false positive was noted. Secondly, two male subjects were screened in saliva using the OraLine® and Intercept® devices after consumption of a single cannabis cigarette containing 25 mg of THC. Saliva was first tested with the OraLine® device and then collected with the Intercept® device for GC/MS confirmation. In one subject, the OraLine® on-site test was positive for THC for 2 h following drug intake with THC concentrations decreasing from 196 to 16 ng/mL, while the test remained positive for 1.5 h for the second subject (THC concentrations ranging from 199 to 11 ng/mL). These preliminary results obtained with the OraLine® IV s.a.t. device indicate more encouraging data for the detection of THC using on-site tests than previous evaluations.
CC :	002B24; 002B30A10; 002B01
FD :	Chromatographie phase gazeuse; Liquide biologique; Salive; Spectrométrie masse; Dépistage; Cannabis; Site; Dispositif médical; Etude comparative; Essai; Exploration; Détection; Diagnostic; Technique; Médecine légale; Aspect médicolégal; Police scientifique; Substance toxicomanogène
FG :	Cannabidaceae; Dicotyledones; Angiospermae; Spermatophyta; Drogue illicite; Drogue récréative
ED :	Gas chromatography; Biological fluid; Saliva; Mass spectrometry; Medical screening; Cannabis; Site; Medical device; Comparative study; Test; Exploration; Detection; Diagnosis; Technique; Legal medicine; Forensic aspect; Forensic science; Drug of abuse
EG :	Cannabidaceae; Dicotyledones; Angiospermae; Spermatophyta; Illicit drug
SD :	Cromatografía fase gaseosa; Líquido biológico; Saliva; Espectrometría masa; Descubrimiento; Cannabis; Sitio; Dispositivo médico; Estudio comparativo; Ensayo; Exploración; Detección; Diagnóstico; Técnica; Medicina legal; Aspecto forense; Ciencia forense; Sustancia toxicomanógena
LO :	INIST-15440.354000133466490140
ID :	06-0403689

Links to Exploration step

Pascal:06-0403689

Le document en format XML

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<front><div type="abstract" xml:lang="en">Saliva or "oral fluid" has been presented as an alternative matrix to document drug use. The non-invasive collection of a saliva sample, which is relatively easy to perform and can be achieved under close supervision, is one of the most important benefits in a driving under the influence situation. Moreover, the presence of A9-tetrahydrocannabinol (THC) in oral fluid is a better indication of recent use than when 11-nor-Δ<sup>9</sup>
-tetrahydrocannabinol-9-carboxylic acid (THC-COOH) is detected in urine, so there is a higher probability that the subject is experiencing pharmacological effects at the time of sampling. In the first part of the study, 27 drug addicts were tested for the presence of THC using the OraLine® IV s.a.t. device to establish the potential of this new on-site DOA detection technique. In parallel, oral fluid was collected with the Intercept® DOA Oral Specimen Collection device and tested for THC by gas chromatography mass spectrometry (GC/MS) after methylation for THC (limit of quantification: 1 ng/mL). The OraLine® device correctly identified nine saliva specimens positive for cannabis with THC concentrations ranging from 3 to 265 ng/mL, but remained negative in four other samples where low THC concentrations were detected by GC/MS (1-13 ng/mL). One false positive was noted. Secondly, two male subjects were screened in saliva using the OraLine® and Intercept® devices after consumption of a single cannabis cigarette containing 25 mg of THC. Saliva was first tested with the OraLine® device and then collected with the Intercept® device for GC/MS confirmation. In one subject, the OraLine® on-site test was positive for THC for 2 h following drug intake with THC concentrations decreasing from 196 to 16 ng/mL, while the test remained positive for 1.5 h for the second subject (THC concentrations ranging from 199 to 11 ng/mL). These preliminary results obtained with the OraLine® IV s.a.t. device indicate more encouraging data for the detection of THC using on-site tests than previous evaluations.</div>
</front>
</TEI>
<inist><standard h6="B"><pA><fA01 i1="01" i2="1"><s0>0379-0738</s0>
</fA01>
<fA02 i1="01"><s0>FSINDR</s0>
</fA02>
<fA03 i2="1"><s0>Forensic sci. int.</s0>
</fA03>
<fA05><s2>161</s2>
</fA05>
<fA06><s2>2-3</s2>
</fA06>
<fA08 i1="01" i2="1" l="ENG"><s1>Oral fluid testing for cannabis : On-site OraLine®. IV s.a.t. device versus GC/MS</s1>
</fA08>
<fA09 i1="01" i2="1" l="ENG"><s1>East meets West in Forensic Toxicology: 43rd TIAFT International Conference, 29th August-2nd September 2005, Seoul, Korea</s1>
</fA09>
<fA11 i1="01" i2="1"><s1>CIRIMELE (Vincent)</s1>
</fA11>
<fA11 i1="02" i2="1"><s1>VILLAIN (Marion)</s1>
</fA11>
<fA11 i1="03" i2="1"><s1>MURA (Patrick)</s1>
</fA11>
<fA11 i1="04" i2="1"><s1>BERNARD (Marc)</s1>
</fA11>
<fA11 i1="05" i2="1"><s1>KINTZ (Pascal)</s1>
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<fA12 i1="01" i2="1"><s1>CHUNG (Heesun)</s1>
<s9>ed.</s9>
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<fA12 i1="02" i2="1"><s1>DRUMMER (Olaf H.)</s1>
<s9>ed.</s9>
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<fA14 i1="01"><s1>Laboratoire ChemTox, 3, rue Grüninger</s1>
<s2>67400 Illkirch</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>5 aut.</sZ>
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<fA14 i1="02"><s1>Laboratoire de biochimie</s1>
<s2>Poitiers</s2>
<s3>FRA</s3>
<sZ>3 aut.</sZ>
</fA14>
<fA14 i1="03"><s1>Urgences Médico-judiciaires</s1>
<s2>Compiègne</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
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<fA15 i1="01"><s1>National Institute of Scientific Investigation, 331-1 Shinwol-7 dong, Yancheon-gu</s1>
<s2>Seoul 158-707</s2>
<s3>KOR</s3>
<sZ>1 aut.</sZ>
</fA15>
<fA15 i1="02"><s1>Department of Forensic Medicine, Victorian Institute of Forensic Medicine, 57-83 Kavanagh Street</s1>
<s2>Southbank 3006, Victoria</s2>
<s3>AUS</s3>
<sZ>2 aut.</sZ>
</fA15>
<fA18 i1="01" i2="1"><s1>International Association of Forensic Toxicologists</s1>
<s3>INT</s3>
<s9>org-cong.</s9>
</fA18>
<fA20><s1>180-184</s1>
</fA20>
<fA21><s1>2006</s1>
</fA21>
<fA23 i1="01"><s0>ENG</s0>
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<s2>15440</s2>
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<fA60><s1>P</s1>
<s2>C</s2>
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<fA66 i1="01"><s0>IRL</s0>
</fA66>
<fC01 i1="01" l="ENG"><s0>Saliva or "oral fluid" has been presented as an alternative matrix to document drug use. The non-invasive collection of a saliva sample, which is relatively easy to perform and can be achieved under close supervision, is one of the most important benefits in a driving under the influence situation. Moreover, the presence of A9-tetrahydrocannabinol (THC) in oral fluid is a better indication of recent use than when 11-nor-Δ<sup>9</sup>
-tetrahydrocannabinol-9-carboxylic acid (THC-COOH) is detected in urine, so there is a higher probability that the subject is experiencing pharmacological effects at the time of sampling. In the first part of the study, 27 drug addicts were tested for the presence of THC using the OraLine® IV s.a.t. device to establish the potential of this new on-site DOA detection technique. In parallel, oral fluid was collected with the Intercept® DOA Oral Specimen Collection device and tested for THC by gas chromatography mass spectrometry (GC/MS) after methylation for THC (limit of quantification: 1 ng/mL). The OraLine® device correctly identified nine saliva specimens positive for cannabis with THC concentrations ranging from 3 to 265 ng/mL, but remained negative in four other samples where low THC concentrations were detected by GC/MS (1-13 ng/mL). One false positive was noted. Secondly, two male subjects were screened in saliva using the OraLine® and Intercept® devices after consumption of a single cannabis cigarette containing 25 mg of THC. Saliva was first tested with the OraLine® device and then collected with the Intercept® device for GC/MS confirmation. In one subject, the OraLine® on-site test was positive for THC for 2 h following drug intake with THC concentrations decreasing from 196 to 16 ng/mL, while the test remained positive for 1.5 h for the second subject (THC concentrations ranging from 199 to 11 ng/mL). These preliminary results obtained with the OraLine® IV s.a.t. device indicate more encouraging data for the detection of THC using on-site tests than previous evaluations.</s0>
</fC01>
<fC02 i1="01" i2="X"><s0>002B24</s0>
</fC02>
<fC02 i1="02" i2="X"><s0>002B30A10</s0>
</fC02>
<fC02 i1="03" i2="X"><s0>002B01</s0>
</fC02>
<fC03 i1="01" i2="X" l="FRE"><s0>Chromatographie phase gazeuse</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="ENG"><s0>Gas chromatography</s0>
<s5>01</s5>
</fC03>
<fC03 i1="01" i2="X" l="SPA"><s0>Cromatografía fase gaseosa</s0>
<s5>01</s5>
</fC03>
<fC03 i1="02" i2="X" l="FRE"><s0>Liquide biologique</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="ENG"><s0>Biological fluid</s0>
<s5>02</s5>
</fC03>
<fC03 i1="02" i2="X" l="SPA"><s0>Líquido biológico</s0>
<s5>02</s5>
</fC03>
<fC03 i1="03" i2="X" l="FRE"><s0>Salive</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="ENG"><s0>Saliva</s0>
<s5>03</s5>
</fC03>
<fC03 i1="03" i2="X" l="SPA"><s0>Saliva</s0>
<s5>03</s5>
</fC03>
<fC03 i1="04" i2="X" l="FRE"><s0>Spectrométrie masse</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="ENG"><s0>Mass spectrometry</s0>
<s5>04</s5>
</fC03>
<fC03 i1="04" i2="X" l="SPA"><s0>Espectrometría masa</s0>
<s5>04</s5>
</fC03>
<fC03 i1="05" i2="X" l="FRE"><s0>Dépistage</s0>
<s5>05</s5>
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<fC03 i1="05" i2="X" l="ENG"><s0>Medical screening</s0>
<s5>05</s5>
</fC03>
<fC03 i1="05" i2="X" l="SPA"><s0>Descubrimiento</s0>
<s5>05</s5>
</fC03>
<fC03 i1="06" i2="X" l="FRE"><s0>Cannabis</s0>
<s2>NS</s2>
<s5>06</s5>
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<s2>NS</s2>
<s5>06</s5>
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<s2>NS</s2>
<s5>06</s5>
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<fC03 i1="07" i2="X" l="FRE"><s0>Site</s0>
<s5>08</s5>
</fC03>
<fC03 i1="07" i2="X" l="ENG"><s0>Site</s0>
<s5>08</s5>
</fC03>
<fC03 i1="07" i2="X" l="SPA"><s0>Sitio</s0>
<s5>08</s5>
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<s5>09</s5>
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<s5>09</s5>
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<s5>09</s5>
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<s5>11</s5>
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<s5>11</s5>
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<s5>11</s5>
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<fC03 i1="10" i2="X" l="FRE"><s0>Essai</s0>
<s5>12</s5>
</fC03>
<fC03 i1="10" i2="X" l="ENG"><s0>Test</s0>
<s5>12</s5>
</fC03>
<fC03 i1="10" i2="X" l="SPA"><s0>Ensayo</s0>
<s5>12</s5>
</fC03>
<fC03 i1="11" i2="X" l="FRE"><s0>Exploration</s0>
<s5>17</s5>
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<s5>17</s5>
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<s5>19</s5>
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<s5>21</s5>
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<s5>25</s5>
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<fC03 i1="16" i2="X" l="SPA"><s0>Aspecto forense</s0>
<s5>25</s5>
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<fC03 i1="17" i2="X" l="FRE"><s0>Police scientifique</s0>
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<fC03 i1="18" i2="X" l="ENG"><s0>Drug of abuse</s0>
<s5>27</s5>
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<s5>27</s5>
</fC03>
<fC07 i1="01" i2="X" l="FRE"><s0>Cannabidaceae</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="01" i2="X" l="ENG"><s0>Cannabidaceae</s0>
<s2>NS</s2>
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<fC07 i1="01" i2="X" l="SPA"><s0>Cannabidaceae</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="02" i2="X" l="FRE"><s0>Dicotyledones</s0>
<s2>NS</s2>
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<fC07 i1="02" i2="X" l="ENG"><s0>Dicotyledones</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="02" i2="X" l="SPA"><s0>Dicotyledones</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="03" i2="X" l="FRE"><s0>Angiospermae</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="03" i2="X" l="ENG"><s0>Angiospermae</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="03" i2="X" l="SPA"><s0>Angiospermae</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="04" i2="X" l="FRE"><s0>Spermatophyta</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="04" i2="X" l="ENG"><s0>Spermatophyta</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="04" i2="X" l="SPA"><s0>Spermatophyta</s0>
<s2>NS</s2>
</fC07>
<fC07 i1="05" i2="X" l="FRE"><s0>Drogue illicite</s0>
<s5>37</s5>
</fC07>
<fC07 i1="05" i2="X" l="ENG"><s0>Illicit drug</s0>
<s5>37</s5>
</fC07>
<fC07 i1="05" i2="X" l="SPA"><s0>Droga ilícita</s0>
<s5>37</s5>
</fC07>
<fC07 i1="06" i2="X" l="FRE"><s0>Drogue récréative</s0>
<s4>INC</s4>
<s5>86</s5>
</fC07>
<fN21><s1>268</s1>
</fN21>
<fN44 i1="01"><s1>OTO</s1>
</fN44>
<fN82><s1>OTO</s1>
</fN82>
</pA>
<pR><fA30 i1="01" i2="1" l="ENG"><s1>International Conference of the International Association of Forensic Toxicologists</s1>
<s2>43</s2>
<s3>Seoul KOR</s3>
<s4>2005-08-29</s4>
</fA30>
</pR>
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<server><NO>PASCAL 06-0403689 INIST</NO>
<ET>Oral fluid testing for cannabis : On-site OraLine®. IV s.a.t. device versus GC/MS</ET>
<AU>CIRIMELE (Vincent); VILLAIN (Marion); MURA (Patrick); BERNARD (Marc); KINTZ (Pascal); CHUNG (Heesun); DRUMMER (Olaf H.)</AU>
<AF>Laboratoire ChemTox, 3, rue Grüninger/67400 Illkirch/France (1 aut., 2 aut., 5 aut.); Laboratoire de biochimie/Poitiers/France (3 aut.); Urgences Médico-judiciaires/Compiègne/France (4 aut.); National Institute of Scientific Investigation, 331-1 Shinwol-7 dong, Yancheon-gu/Seoul 158-707/Corée, République de (1 aut.); Department of Forensic Medicine, Victorian Institute of Forensic Medicine, 57-83 Kavanagh Street/Southbank 3006, Victoria/Australie (2 aut.)</AF>
<DT>Publication en série; Congrès; Niveau analytique</DT>
<SO>Forensic science international; ISSN 0379-0738; Coden FSINDR; Irlande; Da. 2006; Vol. 161; No. 2-3; Pp. 180-184; Bibl. 16 ref.</SO>
<LA>Anglais</LA>
<EA>Saliva or "oral fluid" has been presented as an alternative matrix to document drug use. The non-invasive collection of a saliva sample, which is relatively easy to perform and can be achieved under close supervision, is one of the most important benefits in a driving under the influence situation. Moreover, the presence of A9-tetrahydrocannabinol (THC) in oral fluid is a better indication of recent use than when 11-nor-Δ<sup>9</sup>
-tetrahydrocannabinol-9-ca rboxylic acid (THC-COOH) is detected in urine, so there is a higher probability that the subject is experiencing pharmacological effects at the time of sampling. In the first part of the study, 27 drug addicts were tested for the presence of THC using the OraLine® IV s.a.t. device to establish the potential of this new on-site DOA detection technique. In parallel, oral fluid was collected with the Intercept® DOA Oral Specimen Collection device and tested for THC by gas chromatography mass spectrometry (GC/MS) after methylation for THC (limit of quantification: 1 ng/mL). The OraLine® device correctly identified nine saliva specimens positive for cannabis with THC concentrations ranging from 3 to 265 ng/mL, but remained negative in four other samples where low THC concentrations were detected by GC/MS (1-13 ng/mL). One false positive was noted. Secondly, two male subjects were screened in saliva using the OraLine® and Intercept® devices after consumption of a single cannabis cigarette containing 25 mg of THC. Saliva was first tested with the OraLine® device and then collected with the Intercept® device for GC/MS confirmation. In one subject, the OraLine® on-site test was positive for THC for 2 h following drug intake with THC concentrations decreasing from 196 to 16 ng/mL, while the test remained positive for 1.5 h for the second subject (THC concentrations ranging from 199 to 11 ng/mL). These preliminary results obtained with the OraLine® IV s.a.t. device indicate more encouraging data for the detection of THC using on-site tests than previous evaluations.</EA>
<CC>002B24; 002B30A10; 002B01</CC>
<FD>Chromatographie phase gazeuse; Liquide biologique; Salive; Spectrométrie masse; Dépistage; Cannabis; Site; Dispositif médical; Etude comparative; Essai; Exploration; Détection; Diagnostic; Technique; Médecine légale; Aspect médicolégal; Police scientifique; Substance toxicomanogène</FD>
<FG>Cannabidaceae; Dicotyledones; Angiospermae; Spermatophyta; Drogue illicite; Drogue récréative</FG>
<ED>Gas chromatography; Biological fluid; Saliva; Mass spectrometry; Medical screening; Cannabis; Site; Medical device; Comparative study; Test; Exploration; Detection; Diagnosis; Technique; Legal medicine; Forensic aspect; Forensic science; Drug of abuse</ED>
<EG>Cannabidaceae; Dicotyledones; Angiospermae; Spermatophyta; Illicit drug</EG>
<SD>Cromatografía fase gaseosa; Líquido biológico; Saliva; Espectrometría masa; Descubrimiento; Cannabis; Sitio; Dispositivo médico; Estudio comparativo; Ensayo; Exploración; Detección; Diagnóstico; Técnica; Medicina legal; Aspecto forense; Ciencia forense; Sustancia toxicomanógena</SD>
<LO>INIST-15440.354000133466490140</LO>
<ID>06-0403689</ID>
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Oral fluid testing for cannabis : On-site OraLine®. IV s.a.t. device versus GC/MS

Oral fluid testing for cannabis : On-site OraLine®. IV s.a.t. device versus GC/MS

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