Genome-Wide Measures of Peripheral Blood Dna Methylation and Prostate Cancer Risk in a Prospective Nested Case-Control Study.
Identifieur interne : 004211 ( Ncbi/Curation ); précédent : 004210; suivant : 004212Genome-Wide Measures of Peripheral Blood Dna Methylation and Prostate Cancer Risk in a Prospective Nested Case-Control Study.
Auteurs : Liesel M. Fitzgerald [Australie] ; Haroon Naeem [Australie] ; Enes Makalic [Australie] ; Daniel F. Schmidt [Australie] ; James G. Dowty [Australie] ; Jihoon E. Joo [Australie] ; Chol-Hee Jung [Australie] ; Julie K. Bassett [Australie] ; Pierre-Antoine Dugue [Australie] ; Jessica Chung [Australie] ; Andrew Lonie [Australie] ; Roger L. Milne [Australie] ; Ee Ming Wong [Australie] ; John L. Hopper [Australie] ; Dallas R. English [Australie] ; Gianluca Severi [Australie] ; Laura Baglietto [Australie] ; John Pedersen [Australie] ; Graham G. Giles [Australie] ; Melissa C. Southey [Australie]Source :
- The Prostate [ 1097-0045 ] ; 2017.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Facteurs de risque, Humains, Ilots CpG (physiologie), Mâle, Méthylation de l'ADN (physiologie), Sujet âgé, Tumeurs de la prostate (diagnostic), Tumeurs de la prostate (génétique), Tumeurs de la prostate (sang), Étude d'association pangénomique (), Études cas-témoins, Études de cohortes, Études prospectives.
- MESH :
- diagnostic : Tumeurs de la prostate.
- génétique : Tumeurs de la prostate.
- physiologie : Ilots CpG, Méthylation de l'ADN.
- sang : Tumeurs de la prostate.
- Adulte, Adulte d'âge moyen, Facteurs de risque, Humains, Mâle, Sujet âgé, Étude d'association pangénomique, Études cas-témoins, Études de cohortes, Études prospectives.
English descriptors
- KwdEn :
- Adult, Aged, Case-Control Studies, Cohort Studies, CpG Islands (physiology), DNA Methylation (physiology), Genome-Wide Association Study (methods), Humans, Male, Middle Aged, Prospective Studies, Prostatic Neoplasms (blood), Prostatic Neoplasms (diagnosis), Prostatic Neoplasms (genetics), Risk Factors.
- MESH :
- blood : Prostatic Neoplasms.
- diagnosis : Prostatic Neoplasms.
- genetics : Prostatic Neoplasms.
- methods : Genome-Wide Association Study.
- physiology : CpG Islands, DNA Methylation.
- Adult, Aged, Case-Control Studies, Cohort Studies, Humans, Male, Middle Aged, Prospective Studies, Risk Factors.
Abstract
Global measures of peripheral blood DNA methylation have been associated with risk of some malignancies, including breast, bladder, and gastric cancer. Here, we examined genome-wide measures of peripheral blood DNA methylation in prostate cancer and its non-aggressive and aggressive disease forms.
DOI: 10.1002/pros.23289
PubMed: 28116812
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pubmed:28116812Le document en format XML
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<author><name sortKey="Fitzgerald, Liesel M" sort="Fitzgerald, Liesel M" uniqKey="Fitzgerald L" first="Liesel M" last="Fitzgerald">Liesel M. Fitzgerald</name>
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<author><name sortKey="Naeem, Haroon" sort="Naeem, Haroon" uniqKey="Naeem H" first="Haroon" last="Naeem">Haroon Naeem</name>
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<author><name sortKey="Makalic, Enes" sort="Makalic, Enes" uniqKey="Makalic E" first="Enes" last="Makalic">Enes Makalic</name>
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<author><name sortKey="Chung, Jessica" sort="Chung, Jessica" uniqKey="Chung J" first="Jessica" last="Chung">Jessica Chung</name>
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<author><name sortKey="Hopper, John L" sort="Hopper, John L" uniqKey="Hopper J" first="John L" last="Hopper">John L. Hopper</name>
<affiliation wicri:level="4"><nlm:affiliation>Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, University of Melbourne, Parkville, VIC, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
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<orgName type="university">Université de Melbourne</orgName>
<placeName><settlement type="city">Melbourne</settlement>
<region type="état">Victoria (État)</region>
</placeName>
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<author><name sortKey="English, Dallas R" sort="English, Dallas R" uniqKey="English D" first="Dallas R" last="English">Dallas R. English</name>
<affiliation wicri:level="1"><nlm:affiliation>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, VIC, Australia.</nlm:affiliation>
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<wicri:regionArea>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, VIC</wicri:regionArea>
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<author><name sortKey="Severi, Gianluca" sort="Severi, Gianluca" uniqKey="Severi G" first="Gianluca" last="Severi">Gianluca Severi</name>
<affiliation wicri:level="1"><nlm:affiliation>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, VIC, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, VIC</wicri:regionArea>
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<author><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name>
<affiliation wicri:level="1"><nlm:affiliation>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, VIC, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, VIC</wicri:regionArea>
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<author><name sortKey="Pedersen, John" sort="Pedersen, John" uniqKey="Pedersen J" first="John" last="Pedersen">John Pedersen</name>
<affiliation wicri:level="1"><nlm:affiliation>TissuPath, Mount Waverley, Melbourne, VIC, Australia.</nlm:affiliation>
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<wicri:regionArea>TissuPath, Mount Waverley, Melbourne, VIC</wicri:regionArea>
<wicri:noRegion>VIC</wicri:noRegion>
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</author>
<author><name sortKey="Giles, Graham G" sort="Giles, Graham G" uniqKey="Giles G" first="Graham G" last="Giles">Graham G. Giles</name>
<affiliation wicri:level="1"><nlm:affiliation>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, VIC, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, VIC</wicri:regionArea>
<wicri:noRegion>VIC</wicri:noRegion>
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<author><name sortKey="Southey, Melissa C" sort="Southey, Melissa C" uniqKey="Southey M" first="Melissa C" last="Southey">Melissa C. Southey</name>
<affiliation wicri:level="4"><nlm:affiliation>Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne, Parkville, VIC, Australia.</nlm:affiliation>
<country xml:lang="fr">Australie</country>
<wicri:regionArea>Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne, Parkville, VIC</wicri:regionArea>
<orgName type="university">Université de Melbourne</orgName>
<placeName><settlement type="city">Melbourne</settlement>
<region type="état">Victoria (État)</region>
</placeName>
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</analytic>
<series><title level="j">The Prostate</title>
<idno type="eISSN">1097-0045</idno>
<imprint><date when="2017" type="published">2017</date>
</imprint>
</series>
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<term>Aged</term>
<term>Case-Control Studies</term>
<term>Cohort Studies</term>
<term>CpG Islands (physiology)</term>
<term>DNA Methylation (physiology)</term>
<term>Genome-Wide Association Study (methods)</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Prospective Studies</term>
<term>Prostatic Neoplasms (blood)</term>
<term>Prostatic Neoplasms (diagnosis)</term>
<term>Prostatic Neoplasms (genetics)</term>
<term>Risk Factors</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Facteurs de risque</term>
<term>Humains</term>
<term>Ilots CpG (physiologie)</term>
<term>Mâle</term>
<term>Méthylation de l'ADN (physiologie)</term>
<term>Sujet âgé</term>
<term>Tumeurs de la prostate (diagnostic)</term>
<term>Tumeurs de la prostate (génétique)</term>
<term>Tumeurs de la prostate (sang)</term>
<term>Étude d'association pangénomique ()</term>
<term>Études cas-témoins</term>
<term>Études de cohortes</term>
<term>Études prospectives</term>
</keywords>
<keywords scheme="MESH" qualifier="blood" xml:lang="en"><term>Prostatic Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Prostatic Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Tumeurs de la prostate</term>
</keywords>
<keywords scheme="MESH" qualifier="genetics" xml:lang="en"><term>Prostatic Neoplasms</term>
</keywords>
<keywords scheme="MESH" qualifier="génétique" xml:lang="fr"><term>Tumeurs de la prostate</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Genome-Wide Association Study</term>
</keywords>
<keywords scheme="MESH" qualifier="physiologie" xml:lang="fr"><term>Ilots CpG</term>
<term>Méthylation de l'ADN</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>CpG Islands</term>
<term>DNA Methylation</term>
</keywords>
<keywords scheme="MESH" qualifier="sang" xml:lang="fr"><term>Tumeurs de la prostate</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Case-Control Studies</term>
<term>Cohort Studies</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Prospective Studies</term>
<term>Risk Factors</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Facteurs de risque</term>
<term>Humains</term>
<term>Mâle</term>
<term>Sujet âgé</term>
<term>Étude d'association pangénomique</term>
<term>Études cas-témoins</term>
<term>Études de cohortes</term>
<term>Études prospectives</term>
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<front><div type="abstract" xml:lang="en">Global measures of peripheral blood DNA methylation have been associated with risk of some malignancies, including breast, bladder, and gastric cancer. Here, we examined genome-wide measures of peripheral blood DNA methylation in prostate cancer and its non-aggressive and aggressive disease forms.</div>
</front>
</TEI>
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