Increased risk of developing Parkinson's disease for patients with major affective disorder: a register study
Identifieur interne : 001695 ( Istex/Corpus ); précédent : 001694; suivant : 001696Increased risk of developing Parkinson's disease for patients with major affective disorder: a register study
Auteurs : F. M. Nilsson ; L. V. Kessing ; T. G. BolwigSource :
- Acta Psychiatrica Scandinavica [ 0001-690X ] ; 2001-11.
English descriptors
- KwdEn :
- Acta psychiatr scand, Affective, Affective disorder, Affective disorder episode, Affective disorder episodes, Affective disorders, Affective episodes, Affective patients, Anxiety disorders, Auxiliary diagnosis, Basal ganglia, Biol psychiatry, Bipolar disorder, Categorical covariate, Censoring, Cohort, Control group, Control group diagnoses, Control groups, Danish edition, Danish population, Danish registers, Denmark, Depression code, Depressive, Depressive disorder, Depressive disorder patients, Depressive disorders, Diabetes, Diagnosis, Discharge diagnosis, Disease code, Disorder, Epidemiology, Exclusion criteria, Further analysis, Gender, General population, Glial cells, Information bias, Initial diagnosis, Large number, Lithium treatment, Main diagnosis, Major affective disorder, Major depression, Mania code, Manic episode, Many years, Mood disorders, Neurological disorder, Night care, Odds ratio, Osteoarthritis, Oxford university press, Pathological changes, Present study, Primary affective disorder patients, Proportional hazards, Psychiatric epidemiology, Psychiatric hospital, Psychiatry, Regression model, Regression models, Statistical models, Study base, Study cohorts, Substance abuse, Young diabetics.
- Teeft :
- Acta psychiatr scand, Affective, Affective disorder, Affective disorder episode, Affective disorder episodes, Affective disorders, Affective episodes, Affective patients, Anxiety disorders, Auxiliary diagnosis, Basal ganglia, Biol psychiatry, Bipolar disorder, Categorical covariate, Censoring, Cohort, Control group, Control group diagnoses, Control groups, Danish edition, Danish population, Danish registers, Denmark, Depression code, Depressive, Depressive disorder, Depressive disorder patients, Depressive disorders, Diabetes, Diagnosis, Discharge diagnosis, Disease code, Disorder, Epidemiology, Exclusion criteria, Further analysis, Gender, General population, Glial cells, Information bias, Initial diagnosis, Large number, Lithium treatment, Main diagnosis, Major affective disorder, Major depression, Mania code, Manic episode, Many years, Mood disorders, Neurological disorder, Night care, Odds ratio, Osteoarthritis, Oxford university press, Pathological changes, Present study, Primary affective disorder patients, Proportional hazards, Psychiatric epidemiology, Psychiatric hospital, Psychiatry, Regression model, Regression models, Statistical models, Study base, Study cohorts, Substance abuse, Young diabetics.
Abstract
Objective: To investigate whether patients with a diagnosis of affective disorder are at an increased risk of developing Parkinson's disease compared with medically ill control groups.
Url:
DOI: 10.1111/j.1600-0447.2001.00372.x
Links to Exploration step
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<profileDesc><abstract xml:lang="en" style="main"><p>
<hi rend="bold">Objective:</hi>
To investigate whether patients with a diagnosis of affective disorder are at an increased risk of developing Parkinson's disease compared with medically ill control groups.</p>
<p>
<hi rend="bold">Method:</hi>
By linkage of public hospital registers from 1977 to 1993, three study cohorts were identified: patients with affective disorder episodes (mania or depression) and patients with osteoarthritis or diabetes. Time to the first diagnosis of Parkinson's disease was estimated with the use of survival analysis.</p>
<p>
<hi rend="bold">Results:</hi>
A total of 164 385 patients entered the study base. The risk of being given a diagnosis of Parkinson's disease was significantly increased for patients with affective disorder, odds ratio 2.2 (CI 95% 1.7–2.8) compared with osteoarthritis, and depressive disorders, odds ratio 2.2 (CI 95% 1.7–2.9) compared with osteoarthritis.</p>
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<hi rend="bold">Conclusion:</hi>
This study supports the hypothesis of a common aetiology for major affective disorder and Parkinson's disease.</p>
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<titleGroup><title type="tocHeading1">Original Articles</title>
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<correspondenceTo>Flemming Mørkeberg Nilsson, MD, Department of Psychiatry, O 6233, Rigshospitalet, Blegdamsvej 9, DK‐2100 Copenhagen Ø, Denmark</correspondenceTo>
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<contentMeta><unparsedEditorialHistory>Accepted for publication May 21, 2001</unparsedEditorialHistory>
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<titleGroup><title type="main">Increased risk of developing Parkinson's disease for patients with major affective disorder: a register study</title>
<title type="shortAuthors">Nilsson et al.</title>
<title type="short">Affective disorder and Parkinson's disease</title>
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<creator creatorRole="author" xml:id="cr2" affiliationRef="#a1"><personName><givenNames>L. V.</givenNames>
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<keywordGroup xml:lang="en"><keyword xml:id="k1">depressive disorder</keyword>
<keyword xml:id="k2">bipolar disorder</keyword>
<keyword xml:id="k3">Parkinson's disease</keyword>
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<abstractGroup><abstract type="main" xml:lang="en"><p> <b>Objective:</b>
To investigate whether patients with a diagnosis of affective disorder are at an increased risk of developing Parkinson's disease compared with medically ill control groups.</p>
<p> <b>Method:</b>
By linkage of public hospital registers from 1977 to 1993, three study cohorts were identified: patients with affective disorder episodes (mania or depression) and patients with osteoarthritis or diabetes. Time to the first diagnosis of Parkinson's disease was estimated with the use of survival analysis.</p>
<p> <b>Results:</b>
A total of 164 385 patients entered the study base. The risk of being given a diagnosis of Parkinson's disease was significantly increased for patients with affective disorder, odds ratio 2.2 (CI 95% 1.7–2.8) compared with osteoarthritis, and depressive disorders, odds ratio 2.2 (CI 95% 1.7–2.9) compared with osteoarthritis.</p>
<p> <b>Conclusion:</b>
This study supports the hypothesis of a common aetiology for major affective disorder and Parkinson's disease.</p>
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<abstract>Objective: To investigate whether patients with a diagnosis of affective disorder are at an increased risk of developing Parkinson's disease compared with medically ill control groups.</abstract>
<abstract>Method: By linkage of public hospital registers from 1977 to 1993, three study cohorts were identified: patients with affective disorder episodes (mania or depression) and patients with osteoarthritis or diabetes. Time to the first diagnosis of Parkinson's disease was estimated with the use of survival analysis.</abstract>
<abstract>Results: A total of 164 385 patients entered the study base. The risk of being given a diagnosis of Parkinson's disease was significantly increased for patients with affective disorder, odds ratio 2.2 (CI 95% 1.7–2.8) compared with osteoarthritis, and depressive disorders, odds ratio 2.2 (CI 95% 1.7–2.9) compared with osteoarthritis.</abstract>
<abstract>Conclusion: This study supports the hypothesis of a common aetiology for major affective disorder and Parkinson's disease.</abstract>
<subject lang="en"><genre>keywords</genre>
<topic>depressive disorder</topic>
<topic>bipolar disorder</topic>
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