Peritoneal sarcomatosis in pediatric malignancies
Identifieur interne : 000706 ( Istex/Curation ); précédent : 000705; suivant : 000707Peritoneal sarcomatosis in pediatric malignancies
Auteurs : Winston W. Huh [États-Unis] ; Nancy E. Fitzgerald [États-Unis] ; Anita Mahajan [États-Unis] ; Andrea Hayes-Jordan [États-Unis]Source :
- Pediatric Blood & Cancer [ 1545-5009 ] ; 2013-01.
English descriptors
- Teeft :
- Adult patients, Anderson cancer center, Carcinoma, Carcinomatosis, Chemotherapy, Clin, Clin oncol, Clinical presentation, Clinical trial, Colorectal, Colorectal cancer, Continuous hyperthermic, Cytoreductive, Cytoreductive surgery, Desmoplastic, Dissemination, Dsrct, High tumor volume, Hipec, Hyperthermic, Hyperthermic intraperitoneal chemotherapy, Imaging, Intraperitoneal, Malignancy, Mesothelioma, Metastasis, Metastatic, Oncol, Ovarian, Ovarian carcinoma, Pathway, Pediatr, Pediatr blood cancer, Pediatr surg, Pediatric, Pediatric patients, Pediatric sarcomas, Perioperative intraperitoneal chemotherapy, Peritoneal, Peritoneal carcinomatosis, Peritoneal dissemination, Peritoneal mesothelioma, Peritoneal sarcomatosis, Peritoneum, Photodynamic, Photodynamic therapy, Photosensitizing agent, Primary tumor, Receptor tyrosine kinase, Resection, Rhabdomyosarcoma, Round cell tumor, Round cell tumors, Sarcoma, Sarcomatosis, Sugarbaker, Surg, Surg oncol, Surgical, Tissue sarcoma, Tumor cells, Tumor nodules, Young adults.
Abstract
Peritoneal sarcomatosis (PSC) is defined as peritoneal involvement of multiple sarcomatous tumors. Desmoplastic small round cell tumors (DSRCT) and rhabdomyosarcomas are the most common pediatric PSC cases. PSC has been treated with chemotherapy and mainly palliative surgery, but long‐term outcome has been poor. New imaging technologies have improved the evaluation of disease extent and patterns of peritoneal dissemination, and cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy (HIPEC) is being evaluated as a treatment option to prolong remission in pediatric patients. We will review the clinical characteristics, potential biologic mechanisms, radiographic characteristics, and potential therapies for pediatric PSC patients. Pediatr Blood Cancer 2013; 60: 12–17. © 2012 Wiley Periodicals, Inc.
Url:
DOI: 10.1002/pbc.24293
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Desmoplastic small round cell tumors (DSRCT) and rhabdomyosarcomas are the most common pediatric PSC cases. PSC has been treated with chemotherapy and mainly palliative surgery, but long‐term outcome has been poor. New imaging technologies have improved the evaluation of disease extent and patterns of peritoneal dissemination, and cytoreductive surgery followed by hyperthermic intraperitoneal chemotherapy (HIPEC) is being evaluated as a treatment option to prolong remission in pediatric patients. We will review the clinical characteristics, potential biologic mechanisms, radiographic characteristics, and potential therapies for pediatric PSC patients. Pediatr Blood Cancer 2013; 60: 12–17. © 2012 Wiley Periodicals, Inc.</div></front></TEI></record>Pour manipuler ce document sous Unix (Dilib)
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