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Evidence that bone resorption of young men is not increased by high dietary phosphorus obtained from milk and cheese

Identifieur interne : 001671 ( Istex/Corpus ); précédent : 001670; suivant : 001672

Evidence that bone resorption of young men is not increased by high dietary phosphorus obtained from milk and cheese

Auteurs : Brian K. Bizik ; Wei Ding ; Florian L. Cerklewski

Source :

RBID : ISTEX:61B41E5D4301865FC1DFE2732E474C81FE35A1D5

English descriptors

Abstract

Abstract: Our study consisted of two 10-day periods. In period 1, seven young men (22–31 yrs; average weight of 70 kg) were fed food items providing 800 mg P, 1200 mg Ca, 11.7 MJ and 14.5 g nitrogen. In period two, diet phosphorus was doubled to 1600 mg by addition of cheese and milk. Dietary nitrogen and calcium were equalized for the two periods. Comparison of period 2 with 1 showed that serum intact parathyroid hormone tended to increase suggestive of increased bone turnover, but this possibility was not supported by the bone resorption marker, urinary deoxypyridinoline. High dietary phosphorus increased urinary ammonia N excretion which may play a small role in the mechanism of the hypocalciuric effect of P. We conclude that the high phosphorus intake typical of many diets does not promote bone resorption if the calcium to phosphorus ratio is <1:1.5.

Url:
DOI: 10.1016/0271-5317(96)00118-2

Links to Exploration step

ISTEX:61B41E5D4301865FC1DFE2732E474C81FE35A1D5

Le document en format XML

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<title>Evidence that bone resorption of young men is not increased by high dietary phosphorus obtained from milk and cheese</title>
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<title>Evidence that bone resorption of young men is not increased by high dietary phosphorus obtained from milk and cheese</title>
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<name type="personal">
<namePart type="given">Brian K</namePart>
<namePart type="family">Bizik</namePart>
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<affiliation>Oregon State University Department of Nutrition and Food Management Corvallis, OR 97331-5103 USA</affiliation>
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<namePart type="given">Wei</namePart>
<namePart type="family">Ding</namePart>
<namePart type="termsOfAddress">MS</namePart>
<affiliation>Oregon State University Department of Nutrition and Food Management Corvallis, OR 97331-5103 USA</affiliation>
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<name type="personal">
<namePart type="given">Florian L.</namePart>
<namePart type="family">Cerklewski</namePart>
<namePart type="termsOfAddress">PhD</namePart>
<affiliation>Oregon State University Department of Nutrition and Food Management Corvallis, OR 97331-5103 USA</affiliation>
<affiliation>E-mail: cerklewf@ccmail.orst.edu</affiliation>
<description>Correspondence and requests for reprints to Florian L Cerklewski, PhD, Department of Nutrition and Food Management, Oregon State University, Milam Hall 108, Corvallis, OR 97331-5103. (541) 737-0964; FAX (541) 737-6914</description>
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<abstract lang="en">Abstract: Our study consisted of two 10-day periods. In period 1, seven young men (22–31 yrs; average weight of 70 kg) were fed food items providing 800 mg P, 1200 mg Ca, 11.7 MJ and 14.5 g nitrogen. In period two, diet phosphorus was doubled to 1600 mg by addition of cheese and milk. Dietary nitrogen and calcium were equalized for the two periods. Comparison of period 2 with 1 showed that serum intact parathyroid hormone tended to increase suggestive of increased bone turnover, but this possibility was not supported by the bone resorption marker, urinary deoxypyridinoline. High dietary phosphorus increased urinary ammonia N excretion which may play a small role in the mechanism of the hypocalciuric effect of P. We conclude that the high phosphorus intake typical of many diets does not promote bone resorption if the calcium to phosphorus ratio is <1:1.5.</abstract>
<note type="content">Section title: Human study</note>
<subject>
<genre>Keywords</genre>
<topic>Bone</topic>
<topic>Phosphorus</topic>
<topic>Calcium</topic>
<topic>Deoxypyridinoline</topic>
</subject>
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<identifier type="ISSN">0271-5317</identifier>
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<date>1996</date>
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<identifier type="DOI">10.1016/0271-5317(96)00118-2</identifier>
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