Implementation and Operational Research: Computer-Assisted Intervention for Safer Sex in HIV-Positive Men Having Sex With Men: Findings of a European Randomized Multi-Center Trial
Identifieur interne : 000095 ( Pmc/Curation ); précédent : 000094; suivant : 000096Implementation and Operational Research: Computer-Assisted Intervention for Safer Sex in HIV-Positive Men Having Sex With Men: Findings of a European Randomized Multi-Center Trial
Auteurs : Christiana Nöstlinger ; Tom Platteau [Belgique] ; Johannes Bogner [Allemagne] ; Jozefien Buyze [Belgique] ; Joanna Dec-Pietrowska [Pologne] ; Sonia Dias [Portugal] ; John Newbury-Helps [Royaume-Uni] ; Agnes Kocsis [Royaume-Uni] ; Matthias Mueller [Allemagne] ; Daniela Rojas [France] ; Danica Stanekova ; Jacques Van Lankveld [Pays-Bas] ; Robert Colebunders [Belgique]Source :
- Journal of Acquired Immune Deficiency Syndromes (1999) [ 1525-4135 ] ; 2016.
Abstract
Supplemental Digital Content is Available in the Text.
Url:
DOI: 10.1097/QAI.0000000000000882
PubMed: 26866955
PubMed Central: 4770369
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Danica Stanekova<affiliation><nlm:aff id="aff9">National Reference Centre for HIV/AIDS Prevention, Slovak Medical University, Bratislava, Slovak Republic;</nlm:aff><wicri:noCountry code="subfield">Slovak Republic</wicri:noCountry></affiliation>Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Implementation and Operational Research: Computer-Assisted Intervention for Safer Sex in HIV-Positive Men Having Sex With Men: Findings of a European Randomized Multi-Center Trial</title><author><name sortKey="Nostlinger, Christiana" sort="Nostlinger, Christiana" uniqKey="Nostlinger C" first="Christiana" last="Nöstlinger">Christiana Nöstlinger</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Platteau, Tom" sort="Platteau, Tom" uniqKey="Platteau T" first="Tom" last="Platteau">Tom Platteau</name><affiliation wicri:level="1"><nlm:aff id="aff2">Clinical Sciences, Institute of Tropical Medicine, ITM's HIV AIDS Center (IHAC), Antwerp, Belgium;</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Clinical Sciences, Institute of Tropical Medicine, ITM's HIV AIDS Center (IHAC), Antwerp</wicri:regionArea></affiliation></author><author><name sortKey="Bogner, Johannes" sort="Bogner, Johannes" uniqKey="Bogner J" first="Johannes" last="Bogner">Johannes Bogner</name><affiliation wicri:level="1"><nlm:aff id="aff3">Department of Infectious Diseases, Ludwig-Maximilian University, University Hospital Munich, Munich, Germany;</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Infectious Diseases, Ludwig-Maximilian University, University Hospital Munich, Munich</wicri:regionArea></affiliation></author><author><name sortKey="Buyze, Jozefien" sort="Buyze, Jozefien" uniqKey="Buyze J" first="Jozefien" last="Buyze">Jozefien Buyze</name><affiliation wicri:level="1"><nlm:aff id="aff2">Clinical Sciences, Institute of Tropical Medicine, ITM's HIV AIDS Center (IHAC), Antwerp, Belgium;</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Clinical Sciences, Institute of Tropical Medicine, ITM's HIV AIDS Center (IHAC), Antwerp</wicri:regionArea></affiliation></author><author><name sortKey="Dec Pietrowska, Joanna" sort="Dec Pietrowska, Joanna" uniqKey="Dec Pietrowska J" first="Joanna" last="Dec-Pietrowska">Joanna Dec-Pietrowska</name><affiliation wicri:level="1"><nlm:aff id="aff4">Faculty of Education, Sociology, and Health Services, University of Zielona Gora, Zielona Gora, Poland;</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>Faculty of Education, Sociology, and Health Services, University of Zielona Gora, Zielona Gora</wicri:regionArea></affiliation></author><author><name sortKey="Dias, Sonia" sort="Dias, Sonia" uniqKey="Dias S" first="Sonia" last="Dias">Sonia Dias</name><affiliation wicri:level="1"><nlm:aff id="aff5">Institute of Tropical Medicine and Hygiene, Lisbon, Portugal;</nlm:aff><country xml:lang="fr">Portugal</country><wicri:regionArea>Institute of Tropical Medicine and Hygiene, Lisbon</wicri:regionArea></affiliation></author><author><name sortKey="Newbury Helps, John" sort="Newbury Helps, John" uniqKey="Newbury Helps J" first="John" last="Newbury-Helps">John Newbury-Helps</name><affiliation wicri:level="1"><nlm:aff id="aff6">Central North West London NHS Trust, London, United Kingdom;</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Central North West London NHS Trust, London</wicri:regionArea></affiliation></author><author><name sortKey="Kocsis, Agnes" sort="Kocsis, Agnes" uniqKey="Kocsis A" first="Agnes" last="Kocsis">Agnes Kocsis</name><affiliation wicri:level="1"><nlm:aff id="aff6">Central North West London NHS Trust, London, United Kingdom;</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Central North West London NHS Trust, London</wicri:regionArea></affiliation></author><author><name sortKey="Mueller, Matthias" sort="Mueller, Matthias" uniqKey="Mueller M" first="Matthias" last="Mueller">Matthias Mueller</name><affiliation wicri:level="1"><nlm:aff id="aff3">Department of Infectious Diseases, Ludwig-Maximilian University, University Hospital Munich, Munich, Germany;</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Infectious Diseases, Ludwig-Maximilian University, University Hospital Munich, Munich</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff7">Department of Medicine, Center for Infectious Diseases and Travel Medicine and IFB Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany;</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Medicine, Center for Infectious Diseases and Travel Medicine and IFB Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg</wicri:regionArea></affiliation></author><author><name sortKey="Rojas, Daniela" sort="Rojas, Daniela" uniqKey="Rojas D" first="Daniela" last="Rojas">Daniela Rojas</name><affiliation wicri:level="1"><nlm:aff id="aff8">AIDES, Mission Innovation Recherche Expérimentation (MIRE), Paris, France;</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>AIDES, Mission Innovation Recherche Expérimentation (MIRE), Paris</wicri:regionArea></affiliation></author><author><name sortKey="Stanekova, Danica" sort="Stanekova, Danica" uniqKey="Stanekova D" first="Danica" last="Stanekova">Danica Stanekova</name><affiliation><nlm:aff id="aff9">National Reference Centre for HIV/AIDS Prevention, Slovak Medical University, Bratislava, Slovak Republic;</nlm:aff><wicri:noCountry code="subfield">Slovak Republic</wicri:noCountry></affiliation></author><author><name sortKey="Van Lankveld, Jacques" sort="Van Lankveld, Jacques" uniqKey="Van Lankveld J" first="Jacques" last="Van Lankveld">Jacques Van Lankveld</name><affiliation wicri:level="1"><nlm:aff wicri:cut="; and" id="aff10">Faculty of Psychology and Educational Sciences, Open University, Heerlen, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Faculty of Psychology and Educational Sciences, Open University, Heerlen</wicri:regionArea></affiliation></author><author><name sortKey="Colebunders, Robert" sort="Colebunders, Robert" uniqKey="Colebunders R" first="Robert" last="Colebunders">Robert Colebunders</name><affiliation wicri:level="1"><nlm:aff id="aff2">Clinical Sciences, Institute of Tropical Medicine, ITM's HIV AIDS Center (IHAC), Antwerp, Belgium;</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Clinical Sciences, Institute of Tropical Medicine, ITM's HIV AIDS Center (IHAC), Antwerp</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff11">Department of Epidemiology and Social Medicine, University of Antwerp, Antwerp, Belgium.</nlm:aff><country xml:lang="fr" wicri:curation="lc">Belgique</country><wicri:regionArea>Department of Epidemiology and Social Medicine, University of Antwerp, Antwerp</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">26866955</idno><idno type="pmc">4770369</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770369</idno><idno type="RBID">PMC:4770369</idno><idno type="doi">10.1097/QAI.0000000000000882</idno><date when="2016">2016</date><idno type="wicri:Area/Pmc/Corpus">000095</idno><idno type="wicri:Area/Pmc/Curation">000095</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Implementation and Operational Research: Computer-Assisted Intervention for Safer Sex in HIV-Positive Men Having Sex With Men: Findings of a European Randomized Multi-Center Trial</title><author><name sortKey="Nostlinger, Christiana" sort="Nostlinger, Christiana" uniqKey="Nostlinger C" first="Christiana" last="Nöstlinger">Christiana Nöstlinger</name><affiliation><nlm:aff id="aff1"></nlm:aff></affiliation></author><author><name sortKey="Platteau, Tom" sort="Platteau, Tom" uniqKey="Platteau T" first="Tom" last="Platteau">Tom Platteau</name><affiliation wicri:level="1"><nlm:aff id="aff2">Clinical Sciences, Institute of Tropical Medicine, ITM's HIV AIDS Center (IHAC), Antwerp, Belgium;</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Clinical Sciences, Institute of Tropical Medicine, ITM's HIV AIDS Center (IHAC), Antwerp</wicri:regionArea></affiliation></author><author><name sortKey="Bogner, Johannes" sort="Bogner, Johannes" uniqKey="Bogner J" first="Johannes" last="Bogner">Johannes Bogner</name><affiliation wicri:level="1"><nlm:aff id="aff3">Department of Infectious Diseases, Ludwig-Maximilian University, University Hospital Munich, Munich, Germany;</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Infectious Diseases, Ludwig-Maximilian University, University Hospital Munich, Munich</wicri:regionArea></affiliation></author><author><name sortKey="Buyze, Jozefien" sort="Buyze, Jozefien" uniqKey="Buyze J" first="Jozefien" last="Buyze">Jozefien Buyze</name><affiliation wicri:level="1"><nlm:aff id="aff2">Clinical Sciences, Institute of Tropical Medicine, ITM's HIV AIDS Center (IHAC), Antwerp, Belgium;</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Clinical Sciences, Institute of Tropical Medicine, ITM's HIV AIDS Center (IHAC), Antwerp</wicri:regionArea></affiliation></author><author><name sortKey="Dec Pietrowska, Joanna" sort="Dec Pietrowska, Joanna" uniqKey="Dec Pietrowska J" first="Joanna" last="Dec-Pietrowska">Joanna Dec-Pietrowska</name><affiliation wicri:level="1"><nlm:aff id="aff4">Faculty of Education, Sociology, and Health Services, University of Zielona Gora, Zielona Gora, Poland;</nlm:aff><country xml:lang="fr">Pologne</country><wicri:regionArea>Faculty of Education, Sociology, and Health Services, University of Zielona Gora, Zielona Gora</wicri:regionArea></affiliation></author><author><name sortKey="Dias, Sonia" sort="Dias, Sonia" uniqKey="Dias S" first="Sonia" last="Dias">Sonia Dias</name><affiliation wicri:level="1"><nlm:aff id="aff5">Institute of Tropical 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London</wicri:regionArea></affiliation></author><author><name sortKey="Mueller, Matthias" sort="Mueller, Matthias" uniqKey="Mueller M" first="Matthias" last="Mueller">Matthias Mueller</name><affiliation wicri:level="1"><nlm:aff id="aff3">Department of Infectious Diseases, Ludwig-Maximilian University, University Hospital Munich, Munich, Germany;</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Infectious Diseases, Ludwig-Maximilian University, University Hospital Munich, Munich</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff7">Department of Medicine, Center for Infectious Diseases and Travel Medicine and IFB Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany;</nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea>Department of Medicine, Center for Infectious Diseases and Travel Medicine and IFB Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg</wicri:regionArea></affiliation></author><author><name sortKey="Rojas, Daniela" sort="Rojas, Daniela" uniqKey="Rojas D" first="Daniela" last="Rojas">Daniela Rojas</name><affiliation wicri:level="1"><nlm:aff id="aff8">AIDES, Mission Innovation Recherche Expérimentation (MIRE), Paris, France;</nlm:aff><country xml:lang="fr">France</country><wicri:regionArea>AIDES, Mission Innovation Recherche Expérimentation (MIRE), Paris</wicri:regionArea></affiliation></author><author><name sortKey="Stanekova, Danica" sort="Stanekova, Danica" uniqKey="Stanekova D" first="Danica" last="Stanekova">Danica Stanekova</name><affiliation><nlm:aff id="aff9">National Reference Centre for HIV/AIDS Prevention, Slovak Medical University, Bratislava, Slovak Republic;</nlm:aff><wicri:noCountry code="subfield">Slovak Republic</wicri:noCountry></affiliation></author><author><name sortKey="Van Lankveld, Jacques" sort="Van Lankveld, Jacques" uniqKey="Van Lankveld J" first="Jacques" last="Van Lankveld">Jacques Van Lankveld</name><affiliation wicri:level="1"><nlm:aff wicri:cut="; and" id="aff10">Faculty of Psychology and Educational Sciences, Open University, Heerlen, the Netherlands</nlm:aff><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Faculty of Psychology and Educational Sciences, Open University, Heerlen</wicri:regionArea></affiliation></author><author><name sortKey="Colebunders, Robert" sort="Colebunders, Robert" uniqKey="Colebunders R" first="Robert" last="Colebunders">Robert Colebunders</name><affiliation wicri:level="1"><nlm:aff id="aff2">Clinical Sciences, Institute of Tropical Medicine, ITM's HIV AIDS Center (IHAC), Antwerp, Belgium;</nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea>Clinical Sciences, Institute of Tropical Medicine, ITM's HIV AIDS Center (IHAC), Antwerp</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff11">Department of Epidemiology and Social Medicine, University of Antwerp, Antwerp, 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<front><journal-meta><journal-id journal-id-type="nlm-ta">J Acquir Immune Defic Syndr</journal-id><journal-id journal-id-type="iso-abbrev">J. Acquir. Immune Defic. Syndr</journal-id><journal-id journal-id-type="publisher-id">qai</journal-id><journal-title-group><journal-title>Journal of Acquired Immune Deficiency Syndromes (1999)</journal-title></journal-title-group><issn pub-type="ppub">1525-4135</issn><issn pub-type="epub">1944-7884</issn><publisher><publisher-name>JAIDS Journal of Acquired Immune Deficiency Syndromes</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="pmid">26866955</article-id><article-id pub-id-type="pmc">4770369</article-id><article-id pub-id-type="publisher-id">QAIV15689</article-id><article-id pub-id-type="doi">10.1097/QAI.0000000000000882</article-id><article-id pub-id-type="art-access-id">00016</article-id><article-categories><subj-group subj-group-type="heading"><subject>Epidemiology and Prevention</subject></subj-group></article-categories><title-group><article-title>Implementation and Operational Research: Computer-Assisted Intervention for Safer Sex in HIV-Positive Men Having Sex With Men: Findings of a European Randomized Multi-Center Trial</article-title></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name><surname>Nöstlinger</surname><given-names>Christiana</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff1">*</xref></contrib><contrib contrib-type="author"><name><surname>Platteau</surname><given-names>Tom</given-names></name><degrees>MSc</degrees><xref ref-type="aff" rid="aff2">†</xref></contrib><contrib contrib-type="author"><name><surname>Bogner</surname><given-names>Johannes</given-names></name><degrees>PhD, MD</degrees><xref ref-type="aff" rid="aff3">‡</xref></contrib><contrib contrib-type="author"><name><surname>Buyze</surname><given-names>Jozefien</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff2">†</xref></contrib><contrib contrib-type="author"><name><surname>Dec-Pietrowska</surname><given-names>Joanna</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff4">§</xref></contrib><contrib contrib-type="author"><name><surname>Dias</surname><given-names>Sonia</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff5">‖</xref></contrib><contrib contrib-type="author"><name><surname>Newbury-Helps</surname><given-names>John</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff6">¶</xref></contrib><contrib contrib-type="author"><name><surname>Kocsis</surname><given-names>Agnes</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff6">¶</xref></contrib><contrib contrib-type="author"><name><surname>Mueller</surname><given-names>Matthias</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff3">‡</xref><xref ref-type="aff" rid="aff7">#</xref></contrib><contrib contrib-type="author"><name><surname>Rojas</surname><given-names>Daniela</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff8">**</xref></contrib><contrib contrib-type="author"><name><surname>Stanekova</surname><given-names>Danica</given-names></name><degrees>MD</degrees><xref ref-type="aff" rid="aff9">††</xref></contrib><contrib contrib-type="author"><name><surname>van Lankveld</surname><given-names>Jacques</given-names></name><degrees>PhD</degrees><xref ref-type="aff" rid="aff10">‡‡</xref></contrib><contrib contrib-type="author"><name><surname>Colebunders</surname><given-names>Robert</given-names></name><degrees>MD, PhD</degrees><xref ref-type="aff" rid="aff2">†</xref><xref ref-type="aff" rid="aff11">§§</xref></contrib><contrib contrib-type="author"><collab>the Eurosupport Study Group</collab></contrib><aff id="aff1">Departments of<label>*</label>Public Health;</aff><aff id="aff2"><label>†</label>Clinical Sciences, Institute of Tropical Medicine, ITM's HIV AIDS Center (IHAC), Antwerp, Belgium;</aff><aff id="aff3"><label>‡</label>Department of Infectious Diseases, Ludwig-Maximilian University, University Hospital Munich, Munich, Germany;</aff><aff id="aff4"><label>§</label>Faculty of Education, Sociology, and Health Services, University of Zielona Gora, Zielona Gora, Poland;</aff><aff id="aff5"><label>‖</label>Institute of Tropical Medicine and Hygiene, Lisbon, Portugal;</aff><aff id="aff6"><label>¶</label>Central North West London NHS Trust, London, United Kingdom;</aff><aff id="aff7"><label>#</label>Department of Medicine, Center for Infectious Diseases and Travel Medicine and IFB Center for Chronic Immunodeficiency, University Medical Center Freiburg, Freiburg, Germany;</aff><aff id="aff8"><label>**</label>AIDES, Mission Innovation Recherche Expérimentation (MIRE), Paris, France;</aff><aff id="aff9"><label>††</label>National Reference Centre for HIV/AIDS Prevention, Slovak Medical University, Bratislava, Slovak Republic;</aff><aff id="aff10"><label>‡‡</label>Faculty of Psychology and Educational Sciences, Open University, Heerlen, the Netherlands; and</aff><aff id="aff11"><label>§§</label>Department of Epidemiology and Social Medicine, University of Antwerp, Antwerp, Belgium.</aff></contrib-group><author-notes><corresp>Correspondence to: Christiana Nöstlinger, PhD, Department of Public Health, Institute of Tropical Medicine, Nationalestraat 155, B-2000 Antwerp, Belgium (e-mail: <email>cnoestlinger@itg.be</email>).</corresp></author-notes><pub-date pub-type="ppub"><day>1</day><month>3</month><year>2016</year></pub-date><pub-date pub-type="epub"><day>10</day><month>2</month><year>2016</year></pub-date><volume>71</volume><issue>3</issue><fpage>e63</fpage><lpage>e72</lpage><history><date date-type="received"><day>14</day><month>5</month><year>2015</year></date><date date-type="accepted"><day>14</day><month>10</month><year>2015</year></date></history><permissions><copyright-statement>Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.</copyright-statement><copyright-year>2015</copyright-year></permissions><self-uri xlink:type="simple" xlink:href="qai-71-e63.pdf"></self-uri><abstract abstract-type="toc"><p>Supplemental Digital Content is Available in the Text.</p></abstract><abstract><sec><title>Objective:</title><p>Men who have sex with men (MSM) are the key population most affected by HIV in Europe. We performed the first European multicenter, simple-randomized parallel-group study to test the effectiveness of a theory-guided computer-assisted intervention to improve safer sex among HIV-positive men who have sex with men.</p></sec><sec><title>Methods:</title><p>Between February, 2011 and February, 2013, 112 participants were enrolled in 8 different European HIV-care settings. Intervention participants received 3 individual counseling sessions facilitated by trained service providers using computer-assisted tools. The control-group received sexual health advice delivered as part of regular HIV care. Outcome behavior (self-reported condom use at last intercourse; combined HIV transmission risk score), its influencing factors, and mediating variables were assessed at baseline, and at 3 and 6 months follow-up. Mixed effects models were used to compare primary outcomes (condom use at last intercourse, HIV transmission risk score), and mediation analysis to explore intervention effects.</p></sec><sec><title>Results:</title><p>Condom use at last intercourse increased more among intervention than control participants at 3 months follow-up (odds ratio of 3.83; <italic>P</italic> = 0.03), but not significantly at 6 months follow-up. Intervention participants reported a lower transmission risk at 3 months follow-up than controls (odds ratio compared with baseline of 11.53 and 1.28, respectively; <italic>P</italic> = 0.008), but this effect became nonsignificant at 6 months. Intervention effects were mediated by the proximal variables, self-efficacy to negotiate condom use and condom attitudes.</p></sec><sec><title>Conclusions:</title><p>This intervention showed short-term effectiveness. The intervention should be replicated in other settings, eventually investigating if booster-counseling sessions would yield a longer lasting effect.</p></sec></abstract><kwd-group><title>Key Words:</title><kwd>HIV</kwd><kwd>safer sex</kwd><kwd>theory-based intervention</kwd><kwd>condom use</kwd><kwd>men having sex with men</kwd><kwd>behavioral counseling</kwd></kwd-group><custom-meta-group><custom-meta><meta-name>SDC</meta-name><meta-value>T</meta-value></custom-meta><custom-meta><meta-name>STATUS</meta-name><meta-value>ONLINE-ONLY</meta-value></custom-meta></custom-meta-group></article-meta></front></pmc></record>Pour manipuler ce document sous Unix (Dilib)
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