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Review on sedation for gastrointestinal tract endoscopy in children by non-anesthesiologists

Identifieur interne : 000022 ( Pmc/Curation ); précédent : 000021; suivant : 000023

Review on sedation for gastrointestinal tract endoscopy in children by non-anesthesiologists

Auteurs : Rok Orel ; Jernej Brecelj ; Jorge Amil Dias ; Claudio Romano ; Fernanda Barros ; Mike Thomson ; Yvan Vandenplas

Source :

RBID : PMC:4515424

Abstract

AIM: To present evidence and formulate recommendations for sedation in pediatric gastrointestinal (GI) endoscopy by non-anesthesiologists.

METHODS: The databases MEDLINE, Cochrane and EMBASE were searched for the following keywords “endoscopy, GI”, “endoscopy, digestive system” AND “sedation”, “conscious sedation”, “moderate sedation”, “deep sedation” and “hypnotics and sedatives” for publications in English restricted to the pediatric age. We searched additional information published between January 2011 and January 2014. Searches for (upper) GI endoscopy sedation in pediatrics and sedation guidelines by non-anesthesiologists for the adult population were performed.

RESULTS: From the available studies three sedation protocols are highlighted. Propofol, which seems to offer the best balance between efficacy and safety is rarely used by non-anesthesiologists mainly because of legal restrictions. Ketamine and a combination of a benzodiazepine and an opioid are more frequently used. Data regarding other sedatives, anesthetics and adjuvant medications used for pediatric GI endoscopy are also presented.

CONCLUSION: General anesthesia by a multidisciplinary team led by an anesthesiologist is preferred. The creation of sedation teams led by non-anesthesiologists and a careful selection of anesthetic drugs may offer an alternative, but should be in line with national legislation and institutional regulations.


Url:
DOI: 10.4253/wjge.v7.i9.895
PubMed: 26240691
PubMed Central: 4515424

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PMC:4515424

Le document en format XML

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<name sortKey="Orel, Rok" sort="Orel, Rok" uniqKey="Orel R" first="Rok" last="Orel">Rok Orel</name>
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<name sortKey="Brecelj, Jernej" sort="Brecelj, Jernej" uniqKey="Brecelj J" first="Jernej" last="Brecelj">Jernej Brecelj</name>
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<name sortKey="Dias, Jorge Amil" sort="Dias, Jorge Amil" uniqKey="Dias J" first="Jorge Amil" last="Dias">Jorge Amil Dias</name>
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<name sortKey="Romano, Claudio" sort="Romano, Claudio" uniqKey="Romano C" first="Claudio" last="Romano">Claudio Romano</name>
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<name sortKey="Barros, Fernanda" sort="Barros, Fernanda" uniqKey="Barros F" first="Fernanda" last="Barros">Fernanda Barros</name>
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<name sortKey="Thomson, Mike" sort="Thomson, Mike" uniqKey="Thomson M" first="Mike" last="Thomson">Mike Thomson</name>
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<name sortKey="Vandenplas, Yvan" sort="Vandenplas, Yvan" uniqKey="Vandenplas Y" first="Yvan" last="Vandenplas">Yvan Vandenplas</name>
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<series>
<title level="j">World Journal of Gastrointestinal Endoscopy</title>
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<div type="abstract" xml:lang="en">
<p>AIM: To present evidence and formulate recommendations for sedation in pediatric gastrointestinal (GI) endoscopy by non-anesthesiologists.</p>
<p>METHODS: The databases MEDLINE, Cochrane and EMBASE were searched for the following keywords “endoscopy, GI”, “endoscopy, digestive system” AND “sedation”, “conscious sedation”, “moderate sedation”, “deep sedation” and “hypnotics and sedatives” for publications in English restricted to the pediatric age. We searched additional information published between January 2011 and January 2014. Searches for (upper) GI endoscopy sedation in pediatrics and sedation guidelines by non-anesthesiologists for the adult population were performed.</p>
<p>RESULTS: From the available studies three sedation protocols are highlighted. Propofol, which seems to offer the best balance between efficacy and safety is rarely used by non-anesthesiologists mainly because of legal restrictions. Ketamine and a combination of a benzodiazepine and an opioid are more frequently used. Data regarding other sedatives, anesthetics and adjuvant medications used for pediatric GI endoscopy are also presented.</p>
<p>CONCLUSION: General anesthesia by a multidisciplinary team led by an anesthesiologist is preferred. The creation of sedation teams led by non-anesthesiologists and a careful selection of anesthetic drugs may offer an alternative, but should be in line with national legislation and institutional regulations.</p>
</div>
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<journal-id journal-id-type="nlm-ta">World J Gastrointest Endosc</journal-id>
<journal-id journal-id-type="publisher-id">WJGE</journal-id>
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<journal-title>World Journal of Gastrointestinal Endoscopy</journal-title>
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<issn pub-type="ppub">1948-5190</issn>
<issn pub-type="epub">1948-5190</issn>
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<publisher-name>Baishideng Publishing Group Inc</publisher-name>
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<subject>Systematic Reviews</subject>
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<article-title>Review on sedation for gastrointestinal tract endoscopy in children by non-anesthesiologists</article-title>
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<given-names>Jernej</given-names>
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<given-names>Mike</given-names>
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<given-names>Yvan</given-names>
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<aff>Rok Orel, Jernej Brecelj, Children’s Hospital, University Medical Centre Ljubljana, and Medical Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia</aff>
<aff>Jorge Amil Dias, Department of Pediatrics, Hospital S. João, 4202-451 Porto, Portugal</aff>
<aff>Claudio Romano, Pediatric Department, University of Messina, 98122 Messina, Italy</aff>
<aff>Fernanda Barros, Chair of the Paediatric Section of the Portuguese Society of Anaesthesiology, Department of Anesthesiology, Hospital S. João, 4202-451 Porto, Portugal</aff>
<aff>Mike Thomson, Centre for Paediatric Gastroenterology, International Academy of Paediatric Endoscopy Training, Sheffield Children’s Hospital, Weston Bank, Sheffield S10 2TH, United Kingdom</aff>
<aff>Yvan Vandenplas, Department of Pediatrics, UZ Brussel, Vrije Universiteit Brussel, 1090 Brussels, Belgium</aff>
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<author-notes>
<fn>
<p>Author contributions: Orel R and Brecelj J performed search through the literature; Orel R, Brecelj J, Dias JA, Romano C, Barros F, Thomson M and Vandenplas Y wrote the paper and made final approval of the version to be published.</p>
<p>Correspondence to: Yvan Vandenplas, MD, PhD, Department of Pediatrics, UZ Brussel, Vrije Universiteit Brussel, Laarbeeklaan 101, 1090 Brussels, Belgium.
<email>yvan.vandenplas@uzbrussel.be</email>
</p>
<p>Telephone: +32-24-775780 Fax: +32-24-775783</p>
</fn>
</author-notes>
<pub-date pub-type="ppub">
<day>25</day>
<month>7</month>
<year>2015</year>
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<pub-date pub-type="epub">
<day>25</day>
<month>7</month>
<year>2015</year>
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<volume>7</volume>
<issue>9</issue>
<fpage>895</fpage>
<lpage>911</lpage>
<history>
<date date-type="received">
<day>3</day>
<month>4</month>
<year>2015</year>
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<date date-type="rev-recd">
<day>5</day>
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<date date-type="accepted">
<day>18</day>
<month>6</month>
<year>2015</year>
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<permissions>
<copyright-statement>©The Author(s) 2015. Published by Baishideng Publishing Group Inc. All rights reserved.</copyright-statement>
<copyright-year>2015</copyright-year>
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<abstract>
<p>AIM: To present evidence and formulate recommendations for sedation in pediatric gastrointestinal (GI) endoscopy by non-anesthesiologists.</p>
<p>METHODS: The databases MEDLINE, Cochrane and EMBASE were searched for the following keywords “endoscopy, GI”, “endoscopy, digestive system” AND “sedation”, “conscious sedation”, “moderate sedation”, “deep sedation” and “hypnotics and sedatives” for publications in English restricted to the pediatric age. We searched additional information published between January 2011 and January 2014. Searches for (upper) GI endoscopy sedation in pediatrics and sedation guidelines by non-anesthesiologists for the adult population were performed.</p>
<p>RESULTS: From the available studies three sedation protocols are highlighted. Propofol, which seems to offer the best balance between efficacy and safety is rarely used by non-anesthesiologists mainly because of legal restrictions. Ketamine and a combination of a benzodiazepine and an opioid are more frequently used. Data regarding other sedatives, anesthetics and adjuvant medications used for pediatric GI endoscopy are also presented.</p>
<p>CONCLUSION: General anesthesia by a multidisciplinary team led by an anesthesiologist is preferred. The creation of sedation teams led by non-anesthesiologists and a careful selection of anesthetic drugs may offer an alternative, but should be in line with national legislation and institutional regulations.</p>
</abstract>
<kwd-group>
<kwd>Gastro-intestinal endoscopy</kwd>
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<kwd>Sedatives</kwd>
<kwd>Pediatric ages</kwd>
<kwd>Anesthetics</kwd>
<kwd>Analgesics</kwd>
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