Early complications after lung resections at patients treated for lung cancer with and without Neoadjuvant Hemiotheraphy
Identifieur interne : 000992 ( Main/Merge ); précédent : 000991; suivant : 000993Early complications after lung resections at patients treated for lung cancer with and without Neoadjuvant Hemiotheraphy
Auteurs : Goran Kondov ; Simonida Crvenova ; Zoran Spirovski ; Trajanka Trajkovska ; Sashko Jovev ; Irena Kondova-Topuzovska ; Natasha Tolevska ; Borislav KondovSource :
- Macedonian Journal of Medical Sciences [ 1857-5749 ] ; 2012-08-01.
English descriptors
Abstract
Background: Anatomical lung resection offers the best chance of cure for patients with localized lung cancer. Very often late diagnoses, advanced stage of the disease limit radical anatomical surgical resection. Use of neoadjuvant chemotherapy made some of the cases operable, and later they were surgically treated. Aim: to evaluate early (surgical) complications at patients with neoadjuvant therapy. Material and Methods: We compare 36 patients surgically treated with lung resection, before treated with neoadjuvant chemotherapy (3 to 6 cycles with platinum based regiments under protocol) with 42 patients surgically treated without neoadjuvant chemotherapy, in the same period, in the 2009 and 2010. Results: At the group with neoadjuvant chemotherapy we register more intraoperative and early postoperative complications as: bleeding 10 vs. 7, p=0.63, changes in lung vessels 3 vs. 0, p=0.8, prolonged air leak 9 vs. 6, p=0.63, stump fistula (at pneumectomy patients) 2 vs. 0, p=0.76, pneumonia 9 vs. 3, p=0.86, wound infection 2 vs 0, p=0.73, atelectasis 8 vs. 2, p=0.88, prolonged pleural drainage 10 vs. 4, p=0.87. There, also, was no difference in 30 days mortality rate between groups. Conclusions: Neoadjuvant therapy increased theperioperative complications in this group of patients compared with a similar group undergoing anatomical lung resection in the same institution. The most common complication in patients receiving induction chemotherapy was detected at the group with neoadjuvant chemotherapy. Strategies to prevent these complications will be important, especially if chemotherapy before resection becomes the standard for all patients with non-small cell lung cancer
Url:
DOI: 10.3889/mjms.1857-5773.2012.0226
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000509
- to stream Istex, to step Curation: 000509
- to stream Istex, to step Checkpoint: 000604
Links to Exploration step
ISTEX:119C970480A4C86ADD3283ED052066B7E4282540Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">Early complications after lung resections at patients treated for lung cancer with and without Neoadjuvant Hemiotheraphy</title>
<author><name sortKey="Kondov, Goran" sort="Kondov, Goran" uniqKey="Kondov G" first="Goran" last="Kondov">Goran Kondov</name>
</author>
<author><name sortKey="Crvenova, Simonida" sort="Crvenova, Simonida" uniqKey="Crvenova S" first="Simonida" last="Crvenova">Simonida Crvenova</name>
</author>
<author><name sortKey="Spirovski, Zoran" sort="Spirovski, Zoran" uniqKey="Spirovski Z" first="Zoran" last="Spirovski">Zoran Spirovski</name>
</author>
<author><name sortKey="Trajkovska, Trajanka" sort="Trajkovska, Trajanka" uniqKey="Trajkovska T" first="Trajanka" last="Trajkovska">Trajanka Trajkovska</name>
</author>
<author><name sortKey="Jovev, Sashko" sort="Jovev, Sashko" uniqKey="Jovev S" first="Sashko" last="Jovev">Sashko Jovev</name>
</author>
<author><name sortKey="Kondova Topuzovska, Irena" sort="Kondova Topuzovska, Irena" uniqKey="Kondova Topuzovska I" first="Irena" last="Kondova-Topuzovska">Irena Kondova-Topuzovska</name>
</author>
<author><name sortKey="Tolevska, Natasha" sort="Tolevska, Natasha" uniqKey="Tolevska N" first="Natasha" last="Tolevska">Natasha Tolevska</name>
</author>
<author><name sortKey="Kondov, Borislav" sort="Kondov, Borislav" uniqKey="Kondov B" first="Borislav" last="Kondov">Borislav Kondov</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">ISTEX</idno>
<idno type="RBID">ISTEX:119C970480A4C86ADD3283ED052066B7E4282540</idno>
<date when="2012" year="2012">2012</date>
<idno type="doi">10.3889/mjms.1857-5773.2012.0226</idno>
<idno type="url">https://api.istex.fr/document/119C970480A4C86ADD3283ED052066B7E4282540/fulltext/pdf</idno>
<idno type="wicri:Area/Istex/Corpus">000509</idno>
<idno type="wicri:Area/Istex/Curation">000509</idno>
<idno type="wicri:Area/Istex/Checkpoint">000604</idno>
<idno type="wicri:doubleKey">1857-5749:2012:Kondov G:early:complications:after</idno>
<idno type="wicri:Area/Main/Merge">000992</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title level="a" type="main" xml:lang="en">Early complications after lung resections at patients treated for lung cancer with and without Neoadjuvant Hemiotheraphy</title>
<author><name sortKey="Kondov, Goran" sort="Kondov, Goran" uniqKey="Kondov G" first="Goran" last="Kondov">Goran Kondov</name>
<affiliation><wicri:noCountry code="subField">Macedonija</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Crvenova, Simonida" sort="Crvenova, Simonida" uniqKey="Crvenova S" first="Simonida" last="Crvenova">Simonida Crvenova</name>
<affiliation><wicri:noCountry code="subField">Macedonija</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Spirovski, Zoran" sort="Spirovski, Zoran" uniqKey="Spirovski Z" first="Zoran" last="Spirovski">Zoran Spirovski</name>
<affiliation><wicri:noCountry code="subField">Macedonija</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Trajkovska, Trajanka" sort="Trajkovska, Trajanka" uniqKey="Trajkovska T" first="Trajanka" last="Trajkovska">Trajanka Trajkovska</name>
<affiliation><wicri:noCountry code="subField">Macedonija</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Jovev, Sashko" sort="Jovev, Sashko" uniqKey="Jovev S" first="Sashko" last="Jovev">Sashko Jovev</name>
<affiliation><wicri:noCountry code="subField">Macedonija</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Kondova Topuzovska, Irena" sort="Kondova Topuzovska, Irena" uniqKey="Kondova Topuzovska I" first="Irena" last="Kondova-Topuzovska">Irena Kondova-Topuzovska</name>
<affiliation><wicri:noCountry code="subField">Macedonija</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Tolevska, Natasha" sort="Tolevska, Natasha" uniqKey="Tolevska N" first="Natasha" last="Tolevska">Natasha Tolevska</name>
<affiliation><wicri:noCountry code="subField">Macedonija</wicri:noCountry>
</affiliation>
</author>
<author><name sortKey="Kondov, Borislav" sort="Kondov, Borislav" uniqKey="Kondov B" first="Borislav" last="Kondov">Borislav Kondov</name>
<affiliation><wicri:noCountry code="subField">Macedonija</wicri:noCountry>
</affiliation>
</author>
</analytic>
<monogr></monogr>
<series><title level="j">Macedonian Journal of Medical Sciences</title>
<idno type="ISSN">1857-5749</idno>
<idno type="eISSN">1857-5773</idno>
<imprint><publisher>Versita</publisher>
<date type="published" when="2012-08-01">2012-08-01</date>
<biblScope unit="volume">5</biblScope>
<biblScope unit="issue">2</biblScope>
<biblScope unit="page" from="177">177</biblScope>
<biblScope unit="page" to="180">180</biblScope>
</imprint>
<idno type="ISSN">1857-5749</idno>
</series>
<idno type="istex">119C970480A4C86ADD3283ED052066B7E4282540</idno>
<idno type="DOI">10.3889/mjms.1857-5773.2012.0226</idno>
<idno type="ArticleID">mjms.1857-5773.2012.0226</idno>
<idno type="pdf">mjms.1857-5773.2012.0226.pdf</idno>
</biblStruct>
</sourceDesc>
<seriesStmt><idno type="ISSN">1857-5749</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>NSLC; neoadjuvant chemotheraphy; lung resection; complications; only lung resection</term>
</keywords>
</textClass>
<langUsage><language ident="en">en</language>
</langUsage>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Background: Anatomical lung resection offers the best chance of cure for patients with localized lung cancer. Very often late diagnoses, advanced stage of the disease limit radical anatomical surgical resection. Use of neoadjuvant chemotherapy made some of the cases operable, and later they were surgically treated. Aim: to evaluate early (surgical) complications at patients with neoadjuvant therapy. Material and Methods: We compare 36 patients surgically treated with lung resection, before treated with neoadjuvant chemotherapy (3 to 6 cycles with platinum based regiments under protocol) with 42 patients surgically treated without neoadjuvant chemotherapy, in the same period, in the 2009 and 2010. Results: At the group with neoadjuvant chemotherapy we register more intraoperative and early postoperative complications as: bleeding 10 vs. 7, p=0.63, changes in lung vessels 3 vs. 0, p=0.8, prolonged air leak 9 vs. 6, p=0.63, stump fistula (at pneumectomy patients) 2 vs. 0, p=0.76, pneumonia 9 vs. 3, p=0.86, wound infection 2 vs 0, p=0.73, atelectasis 8 vs. 2, p=0.88, prolonged pleural drainage 10 vs. 4, p=0.87. There, also, was no difference in 30 days mortality rate between groups. Conclusions: Neoadjuvant therapy increased theperioperative complications in this group of patients compared with a similar group undergoing anatomical lung resection in the same institution. The most common complication in patients receiving induction chemotherapy was detected at the group with neoadjuvant chemotherapy. Strategies to prevent these complications will be important, especially if chemotherapy before resection becomes the standard for all patients with non-small cell lung cancer</div>
</front>
</TEI>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Belgique/explor/OpenAccessBelV2/Data/Main/Merge
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000992 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Merge/biblio.hfd -nk 000992 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Belgique |area= OpenAccessBelV2 |flux= Main |étape= Merge |type= RBID |clé= ISTEX:119C970480A4C86ADD3283ED052066B7E4282540 |texte= Early complications after lung resections at patients treated for lung cancer with and without Neoadjuvant Hemiotheraphy }}
This area was generated with Dilib version V0.6.25. |