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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Integrative approaches to computational biomedicine</title>
<author><name sortKey="Coveney, Peter V" sort="Coveney, Peter V" uniqKey="Coveney P" first="Peter V." last="Coveney">Peter V. Coveney</name>
<affiliation><nlm:aff id="af1"><addr-line>Centre for Computational Science</addr-line>
,<institution>University College London</institution>
,<addr-line>20 Gordon Street, London WC1H 0AJ</addr-line>
,<country>UK</country>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Diaz Zuccarini, Vanessa" sort="Diaz Zuccarini, Vanessa" uniqKey="Diaz Zuccarini V" first="Vanessa" last="Diaz-Zuccarini">Vanessa Diaz-Zuccarini</name>
<affiliation><nlm:aff id="af2"><addr-line>Department of Mechanical Engineering</addr-line>
,<institution>University College London</institution>
,<addr-line>Torrington Place, London WC1E 7JE</addr-line>
,<country>UK</country>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Graf, Norbert" sort="Graf, Norbert" uniqKey="Graf N" first="Norbert" last="Graf">Norbert Graf</name>
<affiliation><nlm:aff id="af3"><addr-line>Clinic for Paediatric Haematology and Oncology</addr-line>
,<institution>University of the Saarland</institution>
,<addr-line>66123 Saarbrücken</addr-line>
,<country>Germany</country>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hunter, Peter" sort="Hunter, Peter" uniqKey="Hunter P" first="Peter" last="Hunter">Peter Hunter</name>
<affiliation><nlm:aff id="af4"><addr-line>Auckland Bioengineering Institute</addr-line>
,<institution>University of Auckland</institution>
,<addr-line>Auckland 1142</addr-line>
,<country>New Zealand</country>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kohl, Peter" sort="Kohl, Peter" uniqKey="Kohl P" first="Peter" last="Kohl">Peter Kohl</name>
<affiliation><nlm:aff id="af5"><addr-line>National Heart and Lung Institute</addr-line>
,<institution>Imperial College</institution>
<addr-line>, Harefield Hospital, Hill End Road, Harefield UB9 6JH</addr-line>
,<country>UK</country>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Tegner, Jesper" sort="Tegner, Jesper" uniqKey="Tegner J" first="Jesper" last="Tegner">Jesper Tegner</name>
<affiliation><nlm:aff id="af6"><addr-line>Unit of Computational Medicine, Center for Molecular Medicine, Department of Medicine</addr-line>
,<institution>Karolinska University Hospital</institution>
,<addr-line>17176 Solna</addr-line>
,<country>Sweden</country>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Viceconti, Marco" sort="Viceconti, Marco" uniqKey="Viceconti M" first="Marco" last="Viceconti">Marco Viceconti</name>
<affiliation><nlm:aff id="af7"><addr-line>INSIGNEO Institute for In Silico Medicine</addr-line>
,<institution>University of Sheffield</institution>
,<addr-line>Mappin Street, Sheffield S1 3JD</addr-line>
,<country>UK</country>
</nlm:aff>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PMC</idno>
<idno type="pmc">3638491</idno>
<idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3638491</idno>
<idno type="RBID">PMC:3638491</idno>
<idno type="doi">10.1098/rsfs.2013.0003</idno>
<idno type="pmid">NONE</idno>
<date when="2013">2013</date>
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<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Integrative approaches to computational biomedicine</title>
<author><name sortKey="Coveney, Peter V" sort="Coveney, Peter V" uniqKey="Coveney P" first="Peter V." last="Coveney">Peter V. Coveney</name>
<affiliation><nlm:aff id="af1"><addr-line>Centre for Computational Science</addr-line>
,<institution>University College London</institution>
,<addr-line>20 Gordon Street, London WC1H 0AJ</addr-line>
,<country>UK</country>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Diaz Zuccarini, Vanessa" sort="Diaz Zuccarini, Vanessa" uniqKey="Diaz Zuccarini V" first="Vanessa" last="Diaz-Zuccarini">Vanessa Diaz-Zuccarini</name>
<affiliation><nlm:aff id="af2"><addr-line>Department of Mechanical Engineering</addr-line>
,<institution>University College London</institution>
,<addr-line>Torrington Place, London WC1E 7JE</addr-line>
,<country>UK</country>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Graf, Norbert" sort="Graf, Norbert" uniqKey="Graf N" first="Norbert" last="Graf">Norbert Graf</name>
<affiliation><nlm:aff id="af3"><addr-line>Clinic for Paediatric Haematology and Oncology</addr-line>
,<institution>University of the Saarland</institution>
,<addr-line>66123 Saarbrücken</addr-line>
,<country>Germany</country>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Hunter, Peter" sort="Hunter, Peter" uniqKey="Hunter P" first="Peter" last="Hunter">Peter Hunter</name>
<affiliation><nlm:aff id="af4"><addr-line>Auckland Bioengineering Institute</addr-line>
,<institution>University of Auckland</institution>
,<addr-line>Auckland 1142</addr-line>
,<country>New Zealand</country>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Kohl, Peter" sort="Kohl, Peter" uniqKey="Kohl P" first="Peter" last="Kohl">Peter Kohl</name>
<affiliation><nlm:aff id="af5"><addr-line>National Heart and Lung Institute</addr-line>
,<institution>Imperial College</institution>
<addr-line>, Harefield Hospital, Hill End Road, Harefield UB9 6JH</addr-line>
,<country>UK</country>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Tegner, Jesper" sort="Tegner, Jesper" uniqKey="Tegner J" first="Jesper" last="Tegner">Jesper Tegner</name>
<affiliation><nlm:aff id="af6"><addr-line>Unit of Computational Medicine, Center for Molecular Medicine, Department of Medicine</addr-line>
,<institution>Karolinska University Hospital</institution>
,<addr-line>17176 Solna</addr-line>
,<country>Sweden</country>
</nlm:aff>
</affiliation>
</author>
<author><name sortKey="Viceconti, Marco" sort="Viceconti, Marco" uniqKey="Viceconti M" first="Marco" last="Viceconti">Marco Viceconti</name>
<affiliation><nlm:aff id="af7"><addr-line>INSIGNEO Institute for In Silico Medicine</addr-line>
,<institution>University of Sheffield</institution>
,<addr-line>Mappin Street, Sheffield S1 3JD</addr-line>
,<country>UK</country>
</nlm:aff>
</affiliation>
</author>
</analytic>
<series><title level="j">Interface Focus</title>
<idno type="ISSN">2042-8898</idno>
<idno type="eISSN">2042-8901</idno>
<imprint><date when="2013">2013</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
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<profileDesc><textClass></textClass>
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<front><div type="abstract" xml:lang="en"><p>The new discipline of computational biomedicine is concerned with the application of computer-based techniques and particularly modelling and simulation to human health. Since 2007, this discipline has been synonymous, in Europe, with the name given to the European Union's ambitious investment in integrating these techniques with the eventual aim of modelling the human body as a whole: the virtual physiological human. This programme and its successors are expected, over the next decades, to transform the study and practice of healthcare, moving it towards the priorities known as ‘4P's’: predictive, preventative, personalized and participatory medicine.</p>
</div>
</front>
</TEI>
<pmc article-type="introduction"><pmc-comment>The publisher of this article does not allow downloading of the full text in XML form.</pmc-comment>
<front><journal-meta><journal-id journal-id-type="nlm-ta">Interface Focus</journal-id>
<journal-id journal-id-type="iso-abbrev">Interface Focus</journal-id>
<journal-id journal-id-type="publisher-id">RSFS</journal-id>
<journal-id journal-id-type="hwp">royfocus</journal-id>
<journal-title-group><journal-title>Interface Focus</journal-title>
</journal-title-group>
<issn pub-type="ppub">2042-8898</issn>
<issn pub-type="epub">2042-8901</issn>
<publisher><publisher-name>The Royal Society</publisher-name>
</publisher>
</journal-meta>
<article-meta><article-id pub-id-type="pmc">3638491</article-id>
<article-id pub-id-type="doi">10.1098/rsfs.2013.0003</article-id>
<article-id pub-id-type="publisher-id">rsfs20130003</article-id>
<article-categories><subj-group subj-group-type="hwp-journal-coll"><subject>1004</subject>
<subject>44</subject>
</subj-group>
<subj-group subj-group-type="heading"><subject>Introduction</subject>
</subj-group>
<subj-group subj-group-type="leader"><subject>Introduction</subject>
</subj-group>
</article-categories>
<title-group><article-title>Integrative approaches to computational biomedicine</article-title>
<alt-title alt-title-type="short">Computational Biomedicine</alt-title>
</title-group>
<contrib-group><contrib contrib-type="author"><name><surname>Coveney</surname>
<given-names>Peter V.</given-names>
</name>
<xref ref-type="aff" rid="af1">1</xref>
<xref ref-type="corresp" rid="cor1"></xref>
</contrib>
<contrib contrib-type="author"><name><surname>Diaz-Zuccarini</surname>
<given-names>Vanessa</given-names>
</name>
<xref ref-type="aff" rid="af2">2</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Graf</surname>
<given-names>Norbert</given-names>
</name>
<xref ref-type="aff" rid="af3">3</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Hunter</surname>
<given-names>Peter</given-names>
</name>
<xref ref-type="aff" rid="af4">4</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Kohl</surname>
<given-names>Peter</given-names>
</name>
<xref ref-type="aff" rid="af5">5</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Tegner</surname>
<given-names>Jesper</given-names>
</name>
<xref ref-type="aff" rid="af6">6</xref>
</contrib>
<contrib contrib-type="author"><name><surname>Viceconti</surname>
<given-names>Marco</given-names>
</name>
<xref ref-type="aff" rid="af7">7</xref>
</contrib>
</contrib-group>
<aff id="af1"><label>1</label>
<addr-line>Centre for Computational Science</addr-line>
,<institution>University College London</institution>
,<addr-line>20 Gordon Street, London WC1H 0AJ</addr-line>
,<country>UK</country>
</aff>
<aff id="af2"><label>2</label>
<addr-line>Department of Mechanical Engineering</addr-line>
,<institution>University College London</institution>
,<addr-line>Torrington Place, London WC1E 7JE</addr-line>
,<country>UK</country>
</aff>
<aff id="af3"><label>3</label>
<addr-line>Clinic for Paediatric Haematology and Oncology</addr-line>
,<institution>University of the Saarland</institution>
,<addr-line>66123 Saarbrücken</addr-line>
,<country>Germany</country>
</aff>
<aff id="af4"><label>4</label>
<addr-line>Auckland Bioengineering Institute</addr-line>
,<institution>University of Auckland</institution>
,<addr-line>Auckland 1142</addr-line>
,<country>New Zealand</country>
</aff>
<aff id="af5"><label>5</label>
<addr-line>National Heart and Lung Institute</addr-line>
,<institution>Imperial College</institution>
<addr-line>, Harefield Hospital, Hill End Road, Harefield UB9 6JH</addr-line>
,<country>UK</country>
</aff>
<aff id="af6"><label>6</label>
<addr-line>Unit of Computational Medicine, Center for Molecular Medicine, Department of Medicine</addr-line>
,<institution>Karolinska University Hospital</institution>
,<addr-line>17176 Solna</addr-line>
,<country>Sweden</country>
</aff>
<aff id="af7"><label>7</label>
<addr-line>INSIGNEO Institute for In Silico Medicine</addr-line>
,<institution>University of Sheffield</institution>
,<addr-line>Mappin Street, Sheffield S1 3JD</addr-line>
,<country>UK</country>
</aff>
<author-notes><corresp id="cor1">e-mail: <email>p.v.coveney@ucl.ac.uk</email>
</corresp>
<fn fn-type="other"><p>One contribution of 25 to a Theme Issue ‘<ext-link ext-link-type="uri" xlink:href="http://rsfs.royalsocietypublishing.org/content/3/2.toc">The virtual physiological human: integrative approaches to computational biomedicine</ext-link>
’.</p>
</fn>
</author-notes>
<pub-date pub-type="ppub"><day>6</day>
<month>4</month>
<year>2013</year>
</pub-date>
<volume>3</volume>
<issue>2</issue>
<issue-title>Theme Issue 'The virtual physiological human: integrative approaches to computational biomedicine' organized and edited by Peter Coveney, Vanessa Diaz-Zuccarini, Norbert Graf, Peter Hunter, Peter Kohl, Jesper Tegner and Marco Viceconti</issue-title>
<elocation-id>20130003</elocation-id>
<permissions><copyright-statement>© 2013 The Author(s) Published by the Royal Society. All rights reserved.</copyright-statement>
<copyright-year>2013</copyright-year>
</permissions>
<self-uri content-type="pdf" xlink:type="simple" xlink:href="rsfs20130003.pdf"></self-uri>
<abstract><p>The new discipline of computational biomedicine is concerned with the application of computer-based techniques and particularly modelling and simulation to human health. Since 2007, this discipline has been synonymous, in Europe, with the name given to the European Union's ambitious investment in integrating these techniques with the eventual aim of modelling the human body as a whole: the virtual physiological human. This programme and its successors are expected, over the next decades, to transform the study and practice of healthcare, moving it towards the priorities known as ‘4P's’: predictive, preventative, personalized and participatory medicine.</p>
</abstract>
<kwd-group><kwd>computational biomedicine</kwd>
<kwd>virtual physiological human</kwd>
<kwd>to human health</kwd>
</kwd-group>
<custom-meta-group><custom-meta><meta-name>cover-date</meta-name>
<meta-value>April 6, 2013</meta-value>
</custom-meta>
</custom-meta-group>
</article-meta>
</front>
</pmc>
</record>
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