Heparinizable materials, 5. Preparation and FTIR characterization of polyurethane surfaces grafted with heparin‐complexing poly(amido‐amine) chains
Identifieur interne : 001863 ( Istex/Corpus ); précédent : 001862; suivant : 001864Heparinizable materials, 5. Preparation and FTIR characterization of polyurethane surfaces grafted with heparin‐complexing poly(amido‐amine) chains
Auteurs : Rolando Barbucci ; Manuela Benvenuti ; Giuliana Casini ; Paolo Ferruti ; Mila NocentiniSource :
- Die Makromolekulare Chemie [ 0025-116X ] ; 1985-11.
English descriptors
- Teeft :
- Barbucci, Basic nitrogens, Biological tests, Casini, Commercial product, Difference spectra, Difference spectrum, Diisocyanate, Dmso solution, Ferruti, Ftir, Ftir spectra, Ftir spectroscopy, Ftir spectrum, Grafted, Grafted surfaces, Heparin, Heparinizable, Heparinizable materials, Hexamethylene diisocyanate, Isocyanato groups, N2ll, N2ll units, Naoh solution, Polymer, Polyurethane, Polyurethane films, Polyurethane surfaces, Reaction time, Relative intensities, Room temp, Same region, Slow evaporation, Strongest bands.
Abstract
The chains of poly(amido‐amine) (1) were grafted on the surface of two different polyurethanes (2 and 3), one of which being a commercial product. All the chemical steps of the grafting reaction were monitored by chemical analysis and FTIR spectroscopy. The poly(amido‐amine) was found to be able to form a complex with heparin by electrostatic interaction. The heparin can be totally removed by using a 0,1 M NaOH solution. The heparin adsorbing capacity of the two resulting materials was biologically tested. A constant heparin/poly(amido‐amine) ratio, observed for both polyurethane samples, leads to the assumption that the complex formation reaction proceeds via a defined stoichiometry.
Url:
DOI: 10.1002/macp.1985.021861110
Links to Exploration step
ISTEX:EC76409425E0F0FE18B504A09AF165EA1FB78C8FLe document en format XML
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All the chemical steps of the grafting reaction were monitored by chemical analysis and FTIR spectroscopy. The poly(amido‐amine) was found to be able to form a complex with heparin by electrostatic interaction. The heparin can be totally removed by using a 0,1 M NaOH solution. The heparin adsorbing capacity of the two resulting materials was biologically tested. 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All the chemical steps of the grafting reaction were monitored by chemical analysis and FTIR spectroscopy. The poly(amido‐amine) was found to be able to form a complex with heparin by electrostatic interaction. The heparin can be totally removed by using a 0,1 M NaOH solution. The heparin adsorbing capacity of the two resulting materials was biologically tested. A constant heparin/poly(amido‐amine) ratio, observed for both polyurethane samples, leads to the assumption that the complex formation reaction proceeds via a defined stoichiometry.</abstract><qualityIndicators><score>3.616</score><pdfVersion>1.3</pdfVersion><pdfPageSize>432 x 666 pts</pdfPageSize><refBibsNative>true</refBibsNative><abstractCharCount>693</abstractCharCount><pdfWordCount>2368</pdfWordCount><pdfCharCount>14104</pdfCharCount><pdfPageCount>10</pdfPageCount><abstractWordCount>104</abstractWordCount></qualityIndicators><title>Heparinizable materials, 5. 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Preparation and FTIR characterization of polyurethane surfaces grafted with heparin‐complexing poly(amido‐amine) chains</title><author xml:id="author-1"><persName><forename type="first">Rolando</forename><surname>Barbucci</surname></persName><affiliation>C.R.I.S.M.A., Le Scotte‐Nuovo Policlinico, University of Siena, 53100 Siena, Italy</affiliation><affiliation>Dipartimento di Chimica dell'Università di Siena, Piano dei Mantellini 44, 53100 Siena, Italy</affiliation><affiliation>C.R.I.S.M.A., Le Scotte‐Nuovo Policlinico, University of Siena, 53100 Siena, Italy</affiliation></author><author xml:id="author-2"><persName><forename type="first">Manuela</forename><surname>Benvenuti</surname></persName><affiliation>C.R.I.S.M.A., Le Scotte‐Nuovo Policlinico, University of Siena, 53100 Siena, Italy</affiliation></author><author xml:id="author-3"><persName><forename type="first">Giuliana</forename><surname>Casini</surname></persName><affiliation>C.R.I.S.M.A., Le Scotte‐Nuovo Policlinico, University of Siena, 53100 Siena, Italy</affiliation></author><author xml:id="author-4"><persName><forename type="first">Paolo</forename><surname>Ferruti</surname></persName><affiliation>C.R.I.S.M.A., Le Scotte‐Nuovo Policlinico, University of Siena, 53100 Siena, Italy</affiliation></author><author xml:id="author-5"><persName><forename type="first">Mila</forename><surname>Nocentini</surname></persName><affiliation>Dipartimento di Chimica dell'Università di Siena, Piano dei Mantellini 44, 53100 Siena, Italy</affiliation></author></analytic><monogr><title level="j">Die Makromolekulare Chemie</title><title level="j" type="sub">Macromolecular Chemistry and Physics</title><title level="j" type="abbrev">Makromol. 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All the chemical steps of the grafting reaction were monitored by chemical analysis and FTIR spectroscopy. The poly(amido‐amine) was found to be able to form a complex with heparin by electrostatic interaction. The heparin can be totally removed by using a 0,1 <sc>M</sc> NaOH solution. The heparin adsorbing capacity of the two resulting materials was biologically tested. A constant heparin/poly(amido‐amine) ratio, observed for both polyurethane samples, leads to the assumption that the complex formation reaction proceeds via a defined stoichiometry.</p></abstract></abstractGroup></contentMeta><noteGroup><note xml:id="fn1"><p>Part 4, cf.<sup>4</sup>.</p></note></noteGroup></header></component></istex:document></istex:metadataXml><mods version="3.6"><titleInfo lang="en"><title>Heparinizable materials, 5. Preparation and FTIR characterization of polyurethane surfaces grafted with heparin‐complexing poly(amido‐amine) chains</title></titleInfo><titleInfo type="abbreviated" lang="en"><title>Heparinizable materials, 5</title></titleInfo><titleInfo type="alternative" contentType="CDATA" lang="en"><title>Heparinizable materials, 5. Preparation and FTIR characterization of polyurethane surfaces grafted with heparin‐complexing poly(amido‐amine) chains</title></titleInfo><name type="personal"><namePart type="given">Rolando</namePart><namePart type="family">Barbucci</namePart><affiliation>C.R.I.S.M.A., Le Scotte‐Nuovo Policlinico, University of Siena, 53100 Siena, Italy</affiliation><affiliation>Dipartimento di Chimica dell'Università di Siena, Piano dei Mantellini 44, 53100 Siena, Italy</affiliation><affiliation>C.R.I.S.M.A., Le Scotte‐Nuovo Policlinico, University of Siena, 53100 Siena, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Manuela</namePart><namePart type="family">Benvenuti</namePart><affiliation>C.R.I.S.M.A., Le Scotte‐Nuovo Policlinico, University of Siena, 53100 Siena, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Giuliana</namePart><namePart type="family">Casini</namePart><affiliation>C.R.I.S.M.A., Le Scotte‐Nuovo Policlinico, University of Siena, 53100 Siena, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Paolo</namePart><namePart type="family">Ferruti</namePart><affiliation>C.R.I.S.M.A., Le Scotte‐Nuovo Policlinico, University of Siena, 53100 Siena, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><name type="personal"><namePart type="given">Mila</namePart><namePart type="family">Nocentini</namePart><affiliation>Dipartimento di Chimica dell'Università di Siena, Piano dei Mantellini 44, 53100 Siena, Italy</affiliation><role><roleTerm type="text">author</roleTerm></role></name><typeOfResource>text</typeOfResource><genre type="article" displayLabel="article"></genre><originInfo><publisher>Hüthig & Wepf Verlag</publisher><place><placeTerm type="text">Basel</placeTerm></place><dateIssued encoding="w3cdtf">1985-11</dateIssued><dateCaptured encoding="w3cdtf">1985-02-28</dateCaptured><copyrightDate encoding="w3cdtf">1985</copyrightDate></originInfo><language><languageTerm type="code" authority="rfc3066">en</languageTerm><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType><extent unit="figures">5</extent><extent unit="tables">3</extent><extent unit="references">9</extent></physicalDescription><abstract>The chains of poly(amido‐amine) (1) were grafted on the surface of two different polyurethanes (2 and 3), one of which being a commercial product. All the chemical steps of the grafting reaction were monitored by chemical analysis and FTIR spectroscopy. The poly(amido‐amine) was found to be able to form a complex with heparin by electrostatic interaction. The heparin can be totally removed by using a 0,1 M NaOH solution. The heparin adsorbing capacity of the two resulting materials was biologically tested. A constant heparin/poly(amido‐amine) ratio, observed for both polyurethane samples, leads to the assumption that the complex formation reaction proceeds via a defined stoichiometry.</abstract><note type="content">*Part 4, cf.4.</note><relatedItem type="host"><titleInfo><title>Die Makromolekulare Chemie</title><subTitle>Macromolecular Chemistry and Physics</subTitle></titleInfo><titleInfo type="abbreviated"><title>Makromol. Chem.</title></titleInfo><genre type="journal">journal</genre><subject><genre>article-category</genre><topic>Article</topic></subject><identifier type="ISSN">0025-116X</identifier><identifier type="eISSN">0025-116X</identifier><identifier type="DOI">10.1002/(ISSN)0025-116X</identifier><identifier type="PublisherID">MACP</identifier><part><date>1985</date><detail type="volume"><caption>vol.</caption><number>186</number></detail><detail type="issue"><caption>no.</caption><number>11</number></detail><extent unit="pages"><start>2291</start><end>2300</end><total>10</total></extent></part></relatedItem><identifier type="istex">EC76409425E0F0FE18B504A09AF165EA1FB78C8F</identifier><identifier type="DOI">10.1002/macp.1985.021861110</identifier><identifier type="ArticleID">MACP021861110</identifier><accessCondition type="use and reproduction" contentType="copyright">© 1985 Hüthig & Wepf Verlag, Basel</accessCondition><recordInfo><recordContentSource>WILEY</recordContentSource><recordOrigin>Hüthig & Wepf Verlag</recordOrigin></recordInfo></mods></metadata><serie></serie></istex></record>Pour manipuler ce document sous Unix (Dilib)
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