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Endocrine correlates of stress vulnerability.

Identifieur interne : 000A27 ( PubMed/Corpus ); précédent : 000A26; suivant : 000A28

Endocrine correlates of stress vulnerability.

Auteurs : D H Hellhammer ; S. Wade

Source :

RBID : pubmed:8234641

English descriptors

Abstract

Psychological stress is implicated as one element in a constellation of risk factors for the development and maintenance of psychosomatic disease. Endocrine responses to stressful experience vary widely among individuals, and may account for some of the individual variability in vulnerability to development of psychosomatic symptoms under stress. Endocrine stress responsiveness probably has a large genetic component, but is also known to be modifiable by prolonged and/or profound stressful experience. Social and cognitive factors influence the pituitary-adrenal response to stress, and sex differences may also be significant. It may be possible to develop specific tests of endocrine responsiveness, perhaps incorporating psychological and pharmacological challenges, that may serve as markers of chronic stress experience or of vulnerability to psychosomatic disorders.

PubMed: 8234641

Links to Exploration step

pubmed:8234641

Le document en format XML

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<nlm:affiliation>Center for Psychobiological and Psychosomatic Research, Trier University, FRG.</nlm:affiliation>
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<name sortKey="Wade, S" sort="Wade, S" uniqKey="Wade S" first="S" last="Wade">S. Wade</name>
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<div type="abstract" xml:lang="en">Psychological stress is implicated as one element in a constellation of risk factors for the development and maintenance of psychosomatic disease. Endocrine responses to stressful experience vary widely among individuals, and may account for some of the individual variability in vulnerability to development of psychosomatic symptoms under stress. Endocrine stress responsiveness probably has a large genetic component, but is also known to be modifiable by prolonged and/or profound stressful experience. Social and cognitive factors influence the pituitary-adrenal response to stress, and sex differences may also be significant. It may be possible to develop specific tests of endocrine responsiveness, perhaps incorporating psychological and pharmacological challenges, that may serve as markers of chronic stress experience or of vulnerability to psychosomatic disorders.</div>
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