[Idiopathic CD4 lymphocytopenia with lethal Salmonella typhimurium sepsis].
Identifieur interne : 000A02 ( PubMed/Corpus ); précédent : 000A01; suivant : 000A03[Idiopathic CD4 lymphocytopenia with lethal Salmonella typhimurium sepsis].
Auteurs : S. Burg ; W. Weber ; C. KüchererSource :
- Deutsche medizinische Wochenschrift (1946) [ 0012-0472 ] ; 1994.
English descriptors
- KwdEn :
- MESH :
- complications : T-Lymphocytopenia, Idiopathic CD4-Positive.
- etiology : Bacteremia, Salmonella Infections.
- isolation & purification : Salmonella typhimurium.
- Adult, Fatal Outcome, Female, Humans.
Abstract
In April 1991, a then 43-year-old woman fell ill with a systemic cryptococcal infection which responded well to antimycotic treatment. Four months later she was found to have a T-helper cell deficiency (48/microliters, 15%). Since August 1992 she noted an increased tendency towards infections and had recurrent fever bouts over 4 weeks, which led to her hospitalization in January 1993. Repeated HIV tests were negative. During the first 4 days she was free of infection, but developed a temperature of 39.1 degrees C on the fifth day, and within a few hours a fulminant septicaemia with cardiorespiratory failure developed ending fatally the same day. Blood cultures drawn during fever bouts grew Salmonella typhimurium by the time of her death. Lymphocyte differentiation revealed absolute and relative reduction in the number of CD4-lymphocytes (158/microliters; 18%), retrospectively providing the diagnosis of idiopathic CD4-lymphocytopenia.--In cases such as this there is the need of including opportunistic and masked disease entities in the differential diagnosis, even in the absence of HIV infections, and start early treatment.
DOI: 10.1055/s-2008-1058786
PubMed: 8026310
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pubmed:8026310Le document en format XML
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Kücherer</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="1994">1994</date><idno type="RBID">pubmed:8026310</idno><idno type="pmid">8026310</idno><idno type="doi">10.1055/s-2008-1058786</idno><idno type="wicri:Area/PubMed/Corpus">000A02</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000A02</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">[Idiopathic CD4 lymphocytopenia with lethal Salmonella typhimurium sepsis].</title><author><name sortKey="Burg, S" sort="Burg, S" uniqKey="Burg S" first="S" last="Burg">S. Burg</name><affiliation><nlm:affiliation>I. Medizinische Abteilung, Krankenhaus der Barmherzigen Brüder, Trier.</nlm:affiliation></affiliation></author><author><name sortKey="Weber, W" sort="Weber, W" uniqKey="Weber W" first="W" last="Weber">W. Weber</name></author><author><name sortKey="Kucherer, C" sort="Kucherer, C" uniqKey="Kucherer C" first="C" last="Kücherer">C. Kücherer</name></author></analytic><series><title level="j">Deutsche medizinische Wochenschrift (1946)</title><idno type="ISSN">0012-0472</idno><imprint><date when="1994" type="published">1994</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Bacteremia (etiology)</term><term>Fatal Outcome</term><term>Female</term><term>Humans</term><term>Salmonella Infections (etiology)</term><term>Salmonella typhimurium (isolation & purification)</term><term>T-Lymphocytopenia, Idiopathic CD4-Positive (complications)</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>T-Lymphocytopenia, Idiopathic CD4-Positive</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Bacteremia</term><term>Salmonella Infections</term></keywords><keywords scheme="MESH" qualifier="isolation & purification" xml:lang="en"><term>Salmonella typhimurium</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Fatal Outcome</term><term>Female</term><term>Humans</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In April 1991, a then 43-year-old woman fell ill with a systemic cryptococcal infection which responded well to antimycotic treatment. Four months later she was found to have a T-helper cell deficiency (48/microliters, 15%). Since August 1992 she noted an increased tendency towards infections and had recurrent fever bouts over 4 weeks, which led to her hospitalization in January 1993. Repeated HIV tests were negative. During the first 4 days she was free of infection, but developed a temperature of 39.1 degrees C on the fifth day, and within a few hours a fulminant septicaemia with cardiorespiratory failure developed ending fatally the same day. Blood cultures drawn during fever bouts grew Salmonella typhimurium by the time of her death. Lymphocyte differentiation revealed absolute and relative reduction in the number of CD4-lymphocytes (158/microliters; 18%), retrospectively providing the diagnosis of idiopathic CD4-lymphocytopenia.--In cases such as this there is the need of including opportunistic and masked disease entities in the differential diagnosis, even in the absence of HIV infections, and start early treatment.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">8026310</PMID><DateCreated><Year>1994</Year><Month>08</Month><Day>09</Day></DateCreated><DateCompleted><Year>1994</Year><Month>08</Month><Day>09</Day></DateCompleted><DateRevised><Year>2006</Year><Month>11</Month><Day>15</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0012-0472</ISSN><JournalIssue CitedMedium="Print"><Volume>119</Volume><Issue>27</Issue><PubDate><Year>1994</Year><Month>Jul</Month><Day>08</Day></PubDate></JournalIssue><Title>Deutsche medizinische Wochenschrift (1946)</Title><ISOAbbreviation>Dtsch. Med. Wochenschr.</ISOAbbreviation></Journal><ArticleTitle>[Idiopathic CD4 lymphocytopenia with lethal Salmonella typhimurium sepsis].</ArticleTitle><Pagination><MedlinePgn>956-8</MedlinePgn></Pagination><Abstract><AbstractText>In April 1991, a then 43-year-old woman fell ill with a systemic cryptococcal infection which responded well to antimycotic treatment. Four months later she was found to have a T-helper cell deficiency (48/microliters, 15%). Since August 1992 she noted an increased tendency towards infections and had recurrent fever bouts over 4 weeks, which led to her hospitalization in January 1993. Repeated HIV tests were negative. During the first 4 days she was free of infection, but developed a temperature of 39.1 degrees C on the fifth day, and within a few hours a fulminant septicaemia with cardiorespiratory failure developed ending fatally the same day. Blood cultures drawn during fever bouts grew Salmonella typhimurium by the time of her death. Lymphocyte differentiation revealed absolute and relative reduction in the number of CD4-lymphocytes (158/microliters; 18%), retrospectively providing the diagnosis of idiopathic CD4-lymphocytopenia.--In cases such as this there is the need of including opportunistic and masked disease entities in the differential diagnosis, even in the absence of HIV infections, and start early treatment.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Burg</LastName><ForeName>S</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>I. Medizinische Abteilung, Krankenhaus der Barmherzigen Brüder, Trier.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Weber</LastName><ForeName>W</ForeName><Initials>W</Initials></Author><Author ValidYN="Y"><LastName>Kücherer</LastName><ForeName>C</ForeName><Initials>C</Initials></Author></AuthorList><Language>ger</Language><PublicationTypeList><PublicationType UI="D002363">Case Reports</PublicationType><PublicationType UI="D004740">English Abstract</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType></PublicationTypeList><VernacularTitle>Idiopathische CD4-Lymphozytopenie mit letaler Salmonella-typhimurium-Sepsis.</VernacularTitle></Article><MedlineJournalInfo><Country>Germany</Country><MedlineTA>Dtsch Med Wochenschr</MedlineTA><NlmUniqueID>0006723</NlmUniqueID><ISSNLinking>0012-0472</ISSNLinking></MedlineJournalInfo><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D016470" MajorTopicYN="Y">Bacteremia</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017809" MajorTopicYN="N">Fatal Outcome</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D012480" MajorTopicYN="Y">Salmonella Infections</DescriptorName><QualifierName UI="Q000209" MajorTopicYN="N">etiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012486" MajorTopicYN="N">Salmonella typhimurium</DescriptorName><QualifierName UI="Q000302" MajorTopicYN="Y">isolation & purification</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D018344" MajorTopicYN="N">T-Lymphocytopenia, Idiopathic CD4-Positive</DescriptorName><QualifierName UI="Q000150" MajorTopicYN="Y">complications</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1994</Year><Month>7</Month><Day>8</Day></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>1994</Year><Month>7</Month><Day>8</Day><Hour>0</Hour><Minute>1</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>1994</Year><Month>7</Month><Day>8</Day><Hour>0</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">8026310</ArticleId><ArticleId IdType="doi">10.1055/s-2008-1058786</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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