Psychoneuroimmunological correlates of persisting sciatic pain in patients who underwent discectomy.
Identifieur interne : 000920 ( PubMed/Corpus ); précédent : 000919; suivant : 000921Psychoneuroimmunological correlates of persisting sciatic pain in patients who underwent discectomy.
Auteurs : A. Geiss ; E. Varadi ; K. Steinbach ; H W Bauer ; F. AntonSource :
- Neuroscience letters [ 0304-3940 ] ; 1997.
English descriptors
- KwdEn :
- MESH :
- chemical , blood : Hydrocortisone.
- chemical , metabolism : Interleukin-6.
- metabolism : Saliva.
- pathology : Pain, Postoperative, Sciatica.
- physiopathology : Pain, Postoperative, Sciatica.
- Adult, Diskectomy, Female, Humans, Immunohistochemistry, Male, Pain Measurement, Psychoneuroimmunology.
Abstract
Patients suffering from persisting sciatic pain 8 weeks following discectomy were compared with patients displaying low complaints and healthy, pain-free volunteers regarding their interleukin-6 (IL-6) levels, morning cortisol levels and degree of psychological distress. Whereas serum concentrations of IL-6 were measured by collecting blood samples between 0945 and 2400 h in intervals of 45 min, morning cortisol levels were obtained by sampling saliva on five ensuing measurements, beginning immediately after awakening. In addition, questionnaires aimed at measuring depressive mood, somatic symptoms, coping and chronic stress were filled out by the subjects. The patients with ongoing pain displayed significantly elevated IL-6 levels and an attenuated elevation of cortisol secretion after awakening compared to the two other groups. Patients with persisting pain were also suffering more frequently from depressive mood and ongoing work-related strains. In addition, maladaptive coping strategies were favoured by these patients. The presented data support the hypothesis that the persistence of pain in many of the concerned patients may significantly be related to dysfunctional reciprocal relations between neural, endocrine and immune function.
PubMed: 9453216
Links to Exploration step
pubmed:9453216Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Psychoneuroimmunological correlates of persisting sciatic pain in patients who underwent discectomy.</title>
<author><name sortKey="Geiss, A" sort="Geiss, A" uniqKey="Geiss A" first="A" last="Geiss">A. Geiss</name>
<affiliation><nlm:affiliation>Forschungszentrum für Psychobiologie und Psychosomatik, Schwerpunkt Schmerzforschung, Universität Trier, Germany. geissa@fpp.uni-trier.de</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Varadi, E" sort="Varadi, E" uniqKey="Varadi E" first="E" last="Varadi">E. Varadi</name>
</author>
<author><name sortKey="Steinbach, K" sort="Steinbach, K" uniqKey="Steinbach K" first="K" last="Steinbach">K. Steinbach</name>
</author>
<author><name sortKey="Bauer, H W" sort="Bauer, H W" uniqKey="Bauer H" first="H W" last="Bauer">H W Bauer</name>
</author>
<author><name sortKey="Anton, F" sort="Anton, F" uniqKey="Anton F" first="F" last="Anton">F. Anton</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="1997">1997</date>
<idno type="RBID">pubmed:9453216</idno>
<idno type="pmid">9453216</idno>
<idno type="wicri:Area/PubMed/Corpus">000920</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000920</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">Psychoneuroimmunological correlates of persisting sciatic pain in patients who underwent discectomy.</title>
<author><name sortKey="Geiss, A" sort="Geiss, A" uniqKey="Geiss A" first="A" last="Geiss">A. Geiss</name>
<affiliation><nlm:affiliation>Forschungszentrum für Psychobiologie und Psychosomatik, Schwerpunkt Schmerzforschung, Universität Trier, Germany. geissa@fpp.uni-trier.de</nlm:affiliation>
</affiliation>
</author>
<author><name sortKey="Varadi, E" sort="Varadi, E" uniqKey="Varadi E" first="E" last="Varadi">E. Varadi</name>
</author>
<author><name sortKey="Steinbach, K" sort="Steinbach, K" uniqKey="Steinbach K" first="K" last="Steinbach">K. Steinbach</name>
</author>
<author><name sortKey="Bauer, H W" sort="Bauer, H W" uniqKey="Bauer H" first="H W" last="Bauer">H W Bauer</name>
</author>
<author><name sortKey="Anton, F" sort="Anton, F" uniqKey="Anton F" first="F" last="Anton">F. Anton</name>
</author>
</analytic>
<series><title level="j">Neuroscience letters</title>
<idno type="ISSN">0304-3940</idno>
<imprint><date when="1997" type="published">1997</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Diskectomy</term>
<term>Female</term>
<term>Humans</term>
<term>Hydrocortisone (blood)</term>
<term>Immunohistochemistry</term>
<term>Interleukin-6 (metabolism)</term>
<term>Male</term>
<term>Pain Measurement</term>
<term>Pain, Postoperative (pathology)</term>
<term>Pain, Postoperative (physiopathology)</term>
<term>Psychoneuroimmunology</term>
<term>Saliva (metabolism)</term>
<term>Sciatica (pathology)</term>
<term>Sciatica (physiopathology)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Hydrocortisone</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Interleukin-6</term>
</keywords>
<keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Saliva</term>
</keywords>
<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Pain, Postoperative</term>
<term>Sciatica</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Pain, Postoperative</term>
<term>Sciatica</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Diskectomy</term>
<term>Female</term>
<term>Humans</term>
<term>Immunohistochemistry</term>
<term>Male</term>
<term>Pain Measurement</term>
<term>Psychoneuroimmunology</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Patients suffering from persisting sciatic pain 8 weeks following discectomy were compared with patients displaying low complaints and healthy, pain-free volunteers regarding their interleukin-6 (IL-6) levels, morning cortisol levels and degree of psychological distress. Whereas serum concentrations of IL-6 were measured by collecting blood samples between 0945 and 2400 h in intervals of 45 min, morning cortisol levels were obtained by sampling saliva on five ensuing measurements, beginning immediately after awakening. In addition, questionnaires aimed at measuring depressive mood, somatic symptoms, coping and chronic stress were filled out by the subjects. The patients with ongoing pain displayed significantly elevated IL-6 levels and an attenuated elevation of cortisol secretion after awakening compared to the two other groups. Patients with persisting pain were also suffering more frequently from depressive mood and ongoing work-related strains. In addition, maladaptive coping strategies were favoured by these patients. The presented data support the hypothesis that the persistence of pain in many of the concerned patients may significantly be related to dysfunctional reciprocal relations between neural, endocrine and immune function.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">9453216</PMID>
<DateCreated><Year>1998</Year>
<Month>03</Month>
<Day>05</Day>
</DateCreated>
<DateCompleted><Year>1998</Year>
<Month>03</Month>
<Day>05</Day>
</DateCompleted>
<DateRevised><Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0304-3940</ISSN>
<JournalIssue CitedMedium="Print"><Volume>237</Volume>
<Issue>2-3</Issue>
<PubDate><Year>1997</Year>
<Month>Nov</Month>
<Day>21</Day>
</PubDate>
</JournalIssue>
<Title>Neuroscience letters</Title>
<ISOAbbreviation>Neurosci. Lett.</ISOAbbreviation>
</Journal>
<ArticleTitle>Psychoneuroimmunological correlates of persisting sciatic pain in patients who underwent discectomy.</ArticleTitle>
<Pagination><MedlinePgn>65-8</MedlinePgn>
</Pagination>
<Abstract><AbstractText>Patients suffering from persisting sciatic pain 8 weeks following discectomy were compared with patients displaying low complaints and healthy, pain-free volunteers regarding their interleukin-6 (IL-6) levels, morning cortisol levels and degree of psychological distress. Whereas serum concentrations of IL-6 were measured by collecting blood samples between 0945 and 2400 h in intervals of 45 min, morning cortisol levels were obtained by sampling saliva on five ensuing measurements, beginning immediately after awakening. In addition, questionnaires aimed at measuring depressive mood, somatic symptoms, coping and chronic stress were filled out by the subjects. The patients with ongoing pain displayed significantly elevated IL-6 levels and an attenuated elevation of cortisol secretion after awakening compared to the two other groups. Patients with persisting pain were also suffering more frequently from depressive mood and ongoing work-related strains. In addition, maladaptive coping strategies were favoured by these patients. The presented data support the hypothesis that the persistence of pain in many of the concerned patients may significantly be related to dysfunctional reciprocal relations between neural, endocrine and immune function.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Geiss</LastName>
<ForeName>A</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Forschungszentrum für Psychobiologie und Psychosomatik, Schwerpunkt Schmerzforschung, Universität Trier, Germany. geissa@fpp.uni-trier.de</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Varadi</LastName>
<ForeName>E</ForeName>
<Initials>E</Initials>
</Author>
<Author ValidYN="Y"><LastName>Steinbach</LastName>
<ForeName>K</ForeName>
<Initials>K</Initials>
</Author>
<Author ValidYN="Y"><LastName>Bauer</LastName>
<ForeName>H W</ForeName>
<Initials>HW</Initials>
</Author>
<Author ValidYN="Y"><LastName>Anton</LastName>
<ForeName>F</ForeName>
<Initials>F</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016430">Clinical Trial</PublicationType>
<PublicationType UI="D016428">Journal Article</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>Ireland</Country>
<MedlineTA>Neurosci Lett</MedlineTA>
<NlmUniqueID>7600130</NlmUniqueID>
<ISSNLinking>0304-3940</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D015850">Interleukin-6</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>WI4X0X7BPJ</RegistryNumber>
<NameOfSubstance UI="D006854">Hydrocortisone</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D017586" MajorTopicYN="Y">Diskectomy</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D006854" MajorTopicYN="N">Hydrocortisone</DescriptorName>
<QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D007150" MajorTopicYN="N">Immunohistochemistry</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D015850" MajorTopicYN="N">Interleukin-6</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008297" MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010147" MajorTopicYN="N">Pain Measurement</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010149" MajorTopicYN="N">Pain, Postoperative</DescriptorName>
<QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011598" MajorTopicYN="N">Psychoneuroimmunology</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012463" MajorTopicYN="N">Saliva</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D012585" MajorTopicYN="N">Sciatica</DescriptorName>
<QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName>
<QualifierName UI="Q000503" MajorTopicYN="Y">physiopathology</QualifierName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1998</Year>
<Month>2</Month>
<Day>7</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>1998</Year>
<Month>2</Month>
<Day>7</Day>
<Hour>0</Hour>
<Minute>1</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>1998</Year>
<Month>2</Month>
<Day>7</Day>
<Hour>0</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">9453216</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Rhénanie/explor/UnivTrevesV1/Data/PubMed/Corpus
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000920 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd -nk 000920 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Rhénanie |area= UnivTrevesV1 |flux= PubMed |étape= Corpus |type= RBID |clé= pubmed:9453216 |texte= Psychoneuroimmunological correlates of persisting sciatic pain in patients who underwent discectomy. }}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/PubMed/Corpus/RBID.i -Sk "pubmed:9453216" \ | HfdSelect -Kh $EXPLOR_AREA/Data/PubMed/Corpus/biblio.hfd \ | NlmPubMed2Wicri -a UnivTrevesV1
This area was generated with Dilib version V0.6.31. |