Free cortisol awakening responses are influenced by awakening time.
Identifieur interne : 000747 ( PubMed/Corpus ); précédent : 000746; suivant : 000748Free cortisol awakening responses are influenced by awakening time.
Auteurs : Ilona Federenko ; Stefan Wüst ; Dirk H. Hellhammer ; Ralph Dechoux ; Robert Kumsta ; Clemens KirschbaumSource :
- Psychoneuroendocrinology [ 0306-4530 ] ; 2004.
English descriptors
- KwdEn :
- Adrenal Cortex Function Tests (methods), Adult, Arousal (physiology), Biomarkers (analysis), Circadian Rhythm (physiology), Female, Humans, Hydrocortisone (analysis), Hypothalamo-Hypophyseal System (metabolism), Middle Aged, Pituitary-Adrenal System (metabolism), Saliva (chemistry), Wakefulness (physiology).
- MESH :
- chemical , analysis : Biomarkers, Hydrocortisone.
- chemistry : Saliva.
- metabolism : Hypothalamo-Hypophyseal System, Pituitary-Adrenal System.
- methods : Adrenal Cortex Function Tests.
- physiology : Arousal, Circadian Rhythm, Wakefulness.
- Adult, Female, Humans, Middle Aged.
Abstract
Psychobiological investigations on the hypothalamus-pituitary-adrenal (HPA) axis depend on markers that adequately describe the activity of this system. There is evidence that the free cortisol response to awakening, proposed as a marker for the HPA axis, can be influenced by time of awakening. To further investigate this possible confounder, 24 shift working nurses and 31 female students on a regular sleep-wake cycle collected saliva samples 0, 30, 45 and 60 minutes after awakening. Nurses were investigated on the first and second day of their early (awakening: 04:00-05:30 h), late (awakening: 06:00-09:00 h), and night shift (awakening: 11:00-14:00 h), respectively. Students were studied after taking a short nap on two consecutive weekdays (awakening: 18:45-20:30 h). Mean cortisol levels after awakening increased significantly under all three shift conditions (p<0.01), but decreased in the student sample (p<.05). Within the three shift conditions, cortisol responses following waking in the early shift were more pronounced than in late (p<.01) and night shift (p<.05). The present study shows that in a sample with a large range of awakening times, an impact of this variable on the cortisol awakening response can be observed. The data furthermore strongly suggest that waking up per se is insufficient for adrenocortical stimulation.
PubMed: 14604599
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pubmed:14604599Le document en format XML
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Hellhammer</name></author><author><name sortKey="Dechoux, Ralph" sort="Dechoux, Ralph" uniqKey="Dechoux R" first="Ralph" last="Dechoux">Ralph Dechoux</name></author><author><name sortKey="Kumsta, Robert" sort="Kumsta, Robert" uniqKey="Kumsta R" first="Robert" last="Kumsta">Robert Kumsta</name></author><author><name sortKey="Kirschbaum, Clemens" sort="Kirschbaum, Clemens" uniqKey="Kirschbaum C" first="Clemens" last="Kirschbaum">Clemens Kirschbaum</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2004">2004</date><idno type="RBID">pubmed:14604599</idno><idno type="pmid">14604599</idno><idno type="wicri:Area/PubMed/Corpus">000747</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000747</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Free cortisol awakening responses are influenced by awakening time.</title><author><name sortKey="Federenko, Ilona" sort="Federenko, Ilona" uniqKey="Federenko I" first="Ilona" last="Federenko">Ilona Federenko</name><affiliation><nlm:affiliation>Department of Clinical and Theoretical Psychobiology, University of Trier, Karl-Marx-Str. 94-96, 54290 Trier, Germany. ilona@federenko.de</nlm:affiliation></affiliation></author><author><name sortKey="Wust, Stefan" sort="Wust, Stefan" uniqKey="Wust S" first="Stefan" last="Wüst">Stefan Wüst</name></author><author><name sortKey="Hellhammer, Dirk H" sort="Hellhammer, Dirk H" uniqKey="Hellhammer D" first="Dirk H" last="Hellhammer">Dirk H. Hellhammer</name></author><author><name sortKey="Dechoux, Ralph" sort="Dechoux, Ralph" uniqKey="Dechoux R" first="Ralph" last="Dechoux">Ralph Dechoux</name></author><author><name sortKey="Kumsta, Robert" sort="Kumsta, Robert" uniqKey="Kumsta R" first="Robert" last="Kumsta">Robert Kumsta</name></author><author><name sortKey="Kirschbaum, Clemens" sort="Kirschbaum, Clemens" uniqKey="Kirschbaum C" first="Clemens" last="Kirschbaum">Clemens Kirschbaum</name></author></analytic><series><title level="j">Psychoneuroendocrinology</title><idno type="ISSN">0306-4530</idno><imprint><date when="2004" type="published">2004</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adrenal Cortex Function Tests (methods)</term><term>Adult</term><term>Arousal (physiology)</term><term>Biomarkers (analysis)</term><term>Circadian Rhythm (physiology)</term><term>Female</term><term>Humans</term><term>Hydrocortisone (analysis)</term><term>Hypothalamo-Hypophyseal System (metabolism)</term><term>Middle Aged</term><term>Pituitary-Adrenal System (metabolism)</term><term>Saliva (chemistry)</term><term>Wakefulness (physiology)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="analysis" xml:lang="en"><term>Biomarkers</term><term>Hydrocortisone</term></keywords><keywords scheme="MESH" qualifier="chemistry" xml:lang="en"><term>Saliva</term></keywords><keywords scheme="MESH" qualifier="metabolism" xml:lang="en"><term>Hypothalamo-Hypophyseal System</term><term>Pituitary-Adrenal System</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Adrenal Cortex Function Tests</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Arousal</term><term>Circadian Rhythm</term><term>Wakefulness</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Female</term><term>Humans</term><term>Middle Aged</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Psychobiological investigations on the hypothalamus-pituitary-adrenal (HPA) axis depend on markers that adequately describe the activity of this system. There is evidence that the free cortisol response to awakening, proposed as a marker for the HPA axis, can be influenced by time of awakening. To further investigate this possible confounder, 24 shift working nurses and 31 female students on a regular sleep-wake cycle collected saliva samples 0, 30, 45 and 60 minutes after awakening. Nurses were investigated on the first and second day of their early (awakening: 04:00-05:30 h), late (awakening: 06:00-09:00 h), and night shift (awakening: 11:00-14:00 h), respectively. Students were studied after taking a short nap on two consecutive weekdays (awakening: 18:45-20:30 h). Mean cortisol levels after awakening increased significantly under all three shift conditions (p<0.01), but decreased in the student sample (p<.05). Within the three shift conditions, cortisol responses following waking in the early shift were more pronounced than in late (p<.01) and night shift (p<.05). The present study shows that in a sample with a large range of awakening times, an impact of this variable on the cortisol awakening response can be observed. The data furthermore strongly suggest that waking up per se is insufficient for adrenocortical stimulation.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">14604599</PMID><DateCreated><Year>2003</Year><Month>11</Month><Day>07</Day></DateCreated><DateCompleted><Year>2004</Year><Month>04</Month><Day>05</Day></DateCompleted><DateRevised><Year>2015</Year><Month>11</Month><Day>19</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Print">0306-4530</ISSN><JournalIssue CitedMedium="Print"><Volume>29</Volume><Issue>2</Issue><PubDate><Year>2004</Year><Month>Feb</Month></PubDate></JournalIssue><Title>Psychoneuroendocrinology</Title><ISOAbbreviation>Psychoneuroendocrinology</ISOAbbreviation></Journal><ArticleTitle>Free cortisol awakening responses are influenced by awakening time.</ArticleTitle><Pagination><MedlinePgn>174-84</MedlinePgn></Pagination><Abstract><AbstractText>Psychobiological investigations on the hypothalamus-pituitary-adrenal (HPA) axis depend on markers that adequately describe the activity of this system. There is evidence that the free cortisol response to awakening, proposed as a marker for the HPA axis, can be influenced by time of awakening. To further investigate this possible confounder, 24 shift working nurses and 31 female students on a regular sleep-wake cycle collected saliva samples 0, 30, 45 and 60 minutes after awakening. Nurses were investigated on the first and second day of their early (awakening: 04:00-05:30 h), late (awakening: 06:00-09:00 h), and night shift (awakening: 11:00-14:00 h), respectively. Students were studied after taking a short nap on two consecutive weekdays (awakening: 18:45-20:30 h). Mean cortisol levels after awakening increased significantly under all three shift conditions (p<0.01), but decreased in the student sample (p<.05). Within the three shift conditions, cortisol responses following waking in the early shift were more pronounced than in late (p<.01) and night shift (p<.05). The present study shows that in a sample with a large range of awakening times, an impact of this variable on the cortisol awakening response can be observed. The data furthermore strongly suggest that waking up per se is insufficient for adrenocortical stimulation.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Federenko</LastName><ForeName>Ilona</ForeName><Initials>I</Initials><AffiliationInfo><Affiliation>Department of Clinical and Theoretical Psychobiology, University of Trier, Karl-Marx-Str. 94-96, 54290 Trier, Germany. ilona@federenko.de</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Wüst</LastName><ForeName>Stefan</ForeName><Initials>S</Initials></Author><Author ValidYN="Y"><LastName>Hellhammer</LastName><ForeName>Dirk H</ForeName><Initials>DH</Initials></Author><Author ValidYN="Y"><LastName>Dechoux</LastName><ForeName>Ralph</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Kumsta</LastName><ForeName>Robert</ForeName><Initials>R</Initials></Author><Author ValidYN="Y"><LastName>Kirschbaum</LastName><ForeName>Clemens</ForeName><Initials>C</Initials></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016430">Clinical Trial</PublicationType><PublicationType UI="D018848">Controlled Clinical Trial</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType></PublicationTypeList></Article><MedlineJournalInfo><Country>England</Country><MedlineTA>Psychoneuroendocrinology</MedlineTA><NlmUniqueID>7612148</NlmUniqueID><ISSNLinking>0306-4530</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D015415">Biomarkers</NameOfSubstance></Chemical><Chemical><RegistryNumber>WI4X0X7BPJ</RegistryNumber><NameOfSubstance UI="D006854">Hydrocortisone</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000304" MajorTopicYN="N">Adrenal Cortex Function Tests</DescriptorName><QualifierName UI="Q000379" MajorTopicYN="N">methods</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D000328" MajorTopicYN="N">Adult</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D001143" MajorTopicYN="N">Arousal</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015415" MajorTopicYN="N">Biomarkers</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="N">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002940" MajorTopicYN="N">Circadian Rhythm</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006854" MajorTopicYN="N">Hydrocortisone</DescriptorName><QualifierName UI="Q000032" MajorTopicYN="Y">analysis</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D007030" MajorTopicYN="N">Hypothalamo-Hypophyseal System</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010913" MajorTopicYN="N">Pituitary-Adrenal System</DescriptorName><QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012463" MajorTopicYN="N">Saliva</DescriptorName><QualifierName UI="Q000737" MajorTopicYN="N">chemistry</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014851" MajorTopicYN="N">Wakefulness</DescriptorName><QualifierName UI="Q000502" MajorTopicYN="Y">physiology</QualifierName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>2003</Year><Month>11</Month><Day>8</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2004</Year><Month>4</Month><Day>6</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2003</Year><Month>11</Month><Day>8</Day><Hour>5</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">14604599</ArticleId><ArticleId IdType="pii">S0306453003000210</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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