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Reproducibility of continuous arterial spin labeling perfusion MRI after 7 weeks.

Identifieur interne : 000653 ( PubMed/Corpus ); précédent : 000652; suivant : 000654

Reproducibility of continuous arterial spin labeling perfusion MRI after 7 weeks.

Auteurs : Michael Hermes ; Dirk Hagemann ; Patrick Britz ; Stefan Lieser ; Jürgen Rock ; Ewald Naumann ; Christof Walter

Source :

RBID : pubmed:17429703

English descriptors

Abstract

Continuous arterial spin labeling (CASL) is a non-invasive technique for the measurement of cerebral blood flow (CBF). The aim of the present study was to examine the reproducibility of CASL measurements and its suitability to consistently detect differences between groups, regions, and resting states.

DOI: 10.1007/s10334-007-0073-3
PubMed: 17429703

Links to Exploration step

pubmed:17429703

Le document en format XML

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<title xml:lang="en">Reproducibility of continuous arterial spin labeling perfusion MRI after 7 weeks.</title>
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<name sortKey="Hermes, Michael" sort="Hermes, Michael" uniqKey="Hermes M" first="Michael" last="Hermes">Michael Hermes</name>
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<nlm:affiliation>Department of Psychology, University of Trier, Trier, Germany. hermes@uni-trier.de</nlm:affiliation>
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<name sortKey="Hagemann, Dirk" sort="Hagemann, Dirk" uniqKey="Hagemann D" first="Dirk" last="Hagemann">Dirk Hagemann</name>
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<name sortKey="Britz, Patrick" sort="Britz, Patrick" uniqKey="Britz P" first="Patrick" last="Britz">Patrick Britz</name>
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<name sortKey="Lieser, Stefan" sort="Lieser, Stefan" uniqKey="Lieser S" first="Stefan" last="Lieser">Stefan Lieser</name>
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<name sortKey="Rock, Jurgen" sort="Rock, Jurgen" uniqKey="Rock J" first="Jürgen" last="Rock">Jürgen Rock</name>
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<name sortKey="Naumann, Ewald" sort="Naumann, Ewald" uniqKey="Naumann E" first="Ewald" last="Naumann">Ewald Naumann</name>
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<name sortKey="Walter, Christof" sort="Walter, Christof" uniqKey="Walter C" first="Christof" last="Walter">Christof Walter</name>
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<div type="abstract" xml:lang="en">Continuous arterial spin labeling (CASL) is a non-invasive technique for the measurement of cerebral blood flow (CBF). The aim of the present study was to examine the reproducibility of CASL measurements and its suitability to consistently detect differences between groups, regions, and resting states.</div>
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<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Continuous arterial spin labeling (CASL) is a non-invasive technique for the measurement of cerebral blood flow (CBF). The aim of the present study was to examine the reproducibility of CASL measurements and its suitability to consistently detect differences between groups, regions, and resting states.</AbstractText>
<AbstractText Label="MATERIALS AND METHODS" NlmCategory="METHODS">Thirty-eight healthy subjects (19 female) were examined at 1.5 T on two measurement occasions that were seven weeks apart. Resting CBF was measured with eyes open and eyes closed.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">In different regions of interest (ROIs) the repeatability estimates varied between 9 and 19 ml/100 g/min. There were no significant mean differences between occasions in all ROIs (P > 0.05). Greater CBF in the eyes-open than in the eyes-closed state was consistently present in the primary and secondary visual areas. Furthermore, CBF was consistently greater in the right than in the left hemisphere (P < 0.05) and differed between lobes and between arterial territories (P < 0.001). Finally, we consistently observed greater CBF in women than in men (P < 0.001).</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">This study demonstrates the suitability of CASL to consistently detect differences between groups, regions, and resting states even after seven weeks. This emphasizes its usefulness for longitudinal designs.</AbstractText>
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