[Histopathologic diagnostics in endoprosthetics: periprosthetic neosynovialitis, hypersensitivity reaction, and arthrofibrosis].
Identifieur interne : 000577 ( PubMed/Corpus ); précédent : 000576; suivant : 000578[Histopathologic diagnostics in endoprosthetics: periprosthetic neosynovialitis, hypersensitivity reaction, and arthrofibrosis].
Auteurs : V. Krenn ; M. Otto ; L. Morawietz ; T. Hopf ; M. Jakobs ; W. Klauser ; B. Schwantes ; T. GehrkeSource :
- Der Orthopade [ 1433-0431 ] ; 2009.
English descriptors
- KwdEn :
- MESH :
- adverse effects : Prostheses and Implants.
- etiology : Hypersensitivity, Prosthesis-Related Infections, Synovitis.
- pathology : Hypersensitivity, Prosthesis-Related Infections, Synovitis.
- Fibrosis, Humans, Prosthesis Failure.
Abstract
The durability of endoprosthetic implants of the large joints has increased over the last decades. North American studies have shown a 10-year durability of 94% for prosthetic hip implants, and European studies have shown 10-year durabilities of 88-95%. Pathologists differentiate three etiological disease patterns for the"pathology of endoprosthetics" that lead to reduction of implant durability: 1) periprosthetic particle disease (aseptic loosening), 2) infection, and 3) arthrofibrosis. Four types of neosynovitis/periprosthetic membrane have been determined in a consensus classification: particle-induced type (type I), with a mean prosthesis durability (MPD) of 12 years; infectious type (type II), MPD 2.5 years; combined type (type III), MPD 4.2 years; and indeterminate type (type IV), MPD 5.5 years. There are three histopathologic degrees of arthrofibrosis; grade 1 always needs clinical information for diagnosis, whereas grades 2 and 3 are distinct histopathologic entities.
DOI: 10.1007/s00132-008-1400-8
PubMed: 19448983
Links to Exploration step
pubmed:19448983Le document en format XML
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<affiliation><nlm:affiliation>Zentrum für Histologie, Zytologie und Molekulare Diagnostik, Max-Planck-Strasse, Trier, Deutschland. v.krenn@patho-trier.de</nlm:affiliation>
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<author><name sortKey="Otto, M" sort="Otto, M" uniqKey="Otto M" first="M" last="Otto">M. Otto</name>
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<author><name sortKey="Morawietz, L" sort="Morawietz, L" uniqKey="Morawietz L" first="L" last="Morawietz">L. Morawietz</name>
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<author><name sortKey="Hopf, T" sort="Hopf, T" uniqKey="Hopf T" first="T" last="Hopf">T. Hopf</name>
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<author><name sortKey="Jakobs, M" sort="Jakobs, M" uniqKey="Jakobs M" first="M" last="Jakobs">M. Jakobs</name>
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<author><name sortKey="Klauser, W" sort="Klauser, W" uniqKey="Klauser W" first="W" last="Klauser">W. Klauser</name>
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<author><name sortKey="Schwantes, B" sort="Schwantes, B" uniqKey="Schwantes B" first="B" last="Schwantes">B. Schwantes</name>
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<author><name sortKey="Gehrke, T" sort="Gehrke, T" uniqKey="Gehrke T" first="T" last="Gehrke">T. Gehrke</name>
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<term>Humans</term>
<term>Hypersensitivity (etiology)</term>
<term>Hypersensitivity (pathology)</term>
<term>Prostheses and Implants (adverse effects)</term>
<term>Prosthesis Failure</term>
<term>Prosthesis-Related Infections (etiology)</term>
<term>Prosthesis-Related Infections (pathology)</term>
<term>Synovitis (etiology)</term>
<term>Synovitis (pathology)</term>
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<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Prostheses and Implants</term>
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<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Hypersensitivity</term>
<term>Prosthesis-Related Infections</term>
<term>Synovitis</term>
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<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Hypersensitivity</term>
<term>Prosthesis-Related Infections</term>
<term>Synovitis</term>
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<front><div type="abstract" xml:lang="en">The durability of endoprosthetic implants of the large joints has increased over the last decades. North American studies have shown a 10-year durability of 94% for prosthetic hip implants, and European studies have shown 10-year durabilities of 88-95%. Pathologists differentiate three etiological disease patterns for the"pathology of endoprosthetics" that lead to reduction of implant durability: 1) periprosthetic particle disease (aseptic loosening), 2) infection, and 3) arthrofibrosis. Four types of neosynovitis/periprosthetic membrane have been determined in a consensus classification: particle-induced type (type I), with a mean prosthesis durability (MPD) of 12 years; infectious type (type II), MPD 2.5 years; combined type (type III), MPD 4.2 years; and indeterminate type (type IV), MPD 5.5 years. There are three histopathologic degrees of arthrofibrosis; grade 1 always needs clinical information for diagnosis, whereas grades 2 and 3 are distinct histopathologic entities.</div>
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<Title>Der Orthopade</Title>
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<ArticleTitle>[Histopathologic diagnostics in endoprosthetics: periprosthetic neosynovialitis, hypersensitivity reaction, and arthrofibrosis].</ArticleTitle>
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<Abstract><AbstractText>The durability of endoprosthetic implants of the large joints has increased over the last decades. North American studies have shown a 10-year durability of 94% for prosthetic hip implants, and European studies have shown 10-year durabilities of 88-95%. Pathologists differentiate three etiological disease patterns for the"pathology of endoprosthetics" that lead to reduction of implant durability: 1) periprosthetic particle disease (aseptic loosening), 2) infection, and 3) arthrofibrosis. Four types of neosynovitis/periprosthetic membrane have been determined in a consensus classification: particle-induced type (type I), with a mean prosthesis durability (MPD) of 12 years; infectious type (type II), MPD 2.5 years; combined type (type III), MPD 4.2 years; and indeterminate type (type IV), MPD 5.5 years. There are three histopathologic degrees of arthrofibrosis; grade 1 always needs clinical information for diagnosis, whereas grades 2 and 3 are distinct histopathologic entities.</AbstractText>
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<VernacularTitle>Histopathologische Diagnostik in der Endoprothetik: Periprothetische Neosynovialitis, Hypersensitivitätsreaktion und Arthrofibrose.</VernacularTitle>
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<MedlineJournalInfo><Country>Germany</Country>
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<MeshHeadingList><MeshHeading><DescriptorName UI="D005355" MajorTopicYN="N">Fibrosis</DescriptorName>
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<MeshHeading><DescriptorName UI="D006967" MajorTopicYN="N">Hypersensitivity</DescriptorName>
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