[Is bioptic assurance reasonable in patients with Sjögren's syndrome? From focus score to diagnosing vasculitides].
Identifieur interne : 000546 ( PubMed/Corpus ); précédent : 000545; suivant : 000547[Is bioptic assurance reasonable in patients with Sjögren's syndrome? From focus score to diagnosing vasculitides].
Auteurs : V. Krenn ; M. Jakobs ; J. Kriegsmann ; M G Krukemeyer ; A. RiegerSource :
- Zeitschrift fur Rheumatologie [ 1435-1250 ] ; 2010.
English descriptors
- KwdEn :
- Autoantibodies (blood), Biopsy, Capillaries (pathology), Diagnosis, Differential, Humans, Keratoconjunctivitis Sicca (classification), Keratoconjunctivitis Sicca (pathology), Lymphocytosis (pathology), Microscopy, Electron, Muscle, Skeletal (pathology), Myositis (classification), Myositis (pathology), Parotid Gland (pathology), Sialadenitis (classification), Sialadenitis (pathology), Sjogren's Syndrome (classification), Sjogren's Syndrome (pathology), Vasculitis (classification), Vasculitis (pathology).
- MESH :
- chemical , blood : Autoantibodies.
- classification : Keratoconjunctivitis Sicca, Myositis, Sialadenitis, Sjogren's Syndrome, Vasculitis.
- pathology : Capillaries, Keratoconjunctivitis Sicca, Lymphocytosis, Muscle, Skeletal, Myositis, Parotid Gland, Sialadenitis, Sjogren's Syndrome, Vasculitis.
- Biopsy, Diagnosis, Differential, Humans, Microscopy, Electron.
Abstract
Sjögren's syndrome is an autoimmune disease which targets the salivary and lacrimal glands in particular, causing sicca syndrome. Extraglandular manifestations are often seen. Chronic sialadenitis of the parotid gland is the most common symptom to be assessed for differential diagnosis. Common HE and Giemsa slices are histopathologically examined and graduated for lymphocyte infiltration (focus): grade 0: absent, grade 1: slight, grade 2: moderate non-focal infiltration, grade 3: 1 focus (> or =50 lymphocytes) per 4 mm2, grade 4: >1 focus. Grade 3 infiltrates correspond to a focus score of 1, which is one of four disease-classifying criteria acknowledged for diagnosis. Bioptic examination is also performed to rule out different (non-) immunologic sialadenitises, such as the necrotizing or epithelioid-like form (in sarcoidosis), and the extranodal marginal-zone lymphoma. Extraglandular manifestations of Sjögren's syndrome can also be safely diagnosed by histopathological examination. Emphases lie on vasculitides and myositides. Bioptic work-up, therefore, is not only reasonable but also an essential tool for diagnostics in Sjögren's syndrome.
DOI: 10.1007/s00393-009-0514-7
PubMed: 19997922
Links to Exploration step
pubmed:19997922Le document en format XML
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Rieger</name></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2010">2010</date><idno type="RBID">pubmed:19997922</idno><idno type="pmid">19997922</idno><idno type="doi">10.1007/s00393-009-0514-7</idno><idno type="wicri:Area/PubMed/Corpus">000546</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000546</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">[Is bioptic assurance reasonable in patients with Sjögren's syndrome? From focus score to diagnosing vasculitides].</title><author><name sortKey="Krenn, V" sort="Krenn, V" uniqKey="Krenn V" first="V" last="Krenn">V. Krenn</name><affiliation><nlm:affiliation>Zentrum für Histologie, Zytologie und Molekulare Diagnostik, Max-Planck-Str. 18+20, 54296 Trier. krenn@patho-trier.de</nlm:affiliation></affiliation></author><author><name sortKey="Jakobs, M" sort="Jakobs, M" uniqKey="Jakobs M" first="M" last="Jakobs">M. Jakobs</name></author><author><name sortKey="Kriegsmann, J" sort="Kriegsmann, J" uniqKey="Kriegsmann J" first="J" last="Kriegsmann">J. Kriegsmann</name></author><author><name sortKey="Krukemeyer, M G" sort="Krukemeyer, M G" uniqKey="Krukemeyer M" first="M G" last="Krukemeyer">M G Krukemeyer</name></author><author><name sortKey="Rieger, A" sort="Rieger, A" uniqKey="Rieger A" first="A" last="Rieger">A. Rieger</name></author></analytic><series><title level="j">Zeitschrift fur Rheumatologie</title><idno type="eISSN">1435-1250</idno><imprint><date when="2010" type="published">2010</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Autoantibodies (blood)</term><term>Biopsy</term><term>Capillaries (pathology)</term><term>Diagnosis, Differential</term><term>Humans</term><term>Keratoconjunctivitis Sicca (classification)</term><term>Keratoconjunctivitis Sicca (pathology)</term><term>Lymphocytosis (pathology)</term><term>Microscopy, Electron</term><term>Muscle, Skeletal (pathology)</term><term>Myositis (classification)</term><term>Myositis (pathology)</term><term>Parotid Gland (pathology)</term><term>Sialadenitis (classification)</term><term>Sialadenitis (pathology)</term><term>Sjogren's Syndrome (classification)</term><term>Sjogren's Syndrome (pathology)</term><term>Vasculitis (classification)</term><term>Vasculitis (pathology)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="blood" xml:lang="en"><term>Autoantibodies</term></keywords><keywords scheme="MESH" qualifier="classification" xml:lang="en"><term>Keratoconjunctivitis Sicca</term><term>Myositis</term><term>Sialadenitis</term><term>Sjogren's Syndrome</term><term>Vasculitis</term></keywords><keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Capillaries</term><term>Keratoconjunctivitis Sicca</term><term>Lymphocytosis</term><term>Muscle, Skeletal</term><term>Myositis</term><term>Parotid Gland</term><term>Sialadenitis</term><term>Sjogren's Syndrome</term><term>Vasculitis</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Biopsy</term><term>Diagnosis, Differential</term><term>Humans</term><term>Microscopy, Electron</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Sjögren's syndrome is an autoimmune disease which targets the salivary and lacrimal glands in particular, causing sicca syndrome. Extraglandular manifestations are often seen. Chronic sialadenitis of the parotid gland is the most common symptom to be assessed for differential diagnosis. Common HE and Giemsa slices are histopathologically examined and graduated for lymphocyte infiltration (focus): grade 0: absent, grade 1: slight, grade 2: moderate non-focal infiltration, grade 3: 1 focus (> or =50 lymphocytes) per 4 mm2, grade 4: >1 focus. Grade 3 infiltrates correspond to a focus score of 1, which is one of four disease-classifying criteria acknowledged for diagnosis. Bioptic examination is also performed to rule out different (non-) immunologic sialadenitises, such as the necrotizing or epithelioid-like form (in sarcoidosis), and the extranodal marginal-zone lymphoma. Extraglandular manifestations of Sjögren's syndrome can also be safely diagnosed by histopathological examination. Emphases lie on vasculitides and myositides. Bioptic work-up, therefore, is not only reasonable but also an essential tool for diagnostics in Sjögren's syndrome.</div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">19997922</PMID><DateCreated><Year>2010</Year><Month>01</Month><Day>21</Day></DateCreated><DateCompleted><Year>2010</Year><Month>05</Month><Day>05</Day></DateCompleted><DateRevised><Year>2010</Year><Month>01</Month><Day>21</Day></DateRevised><Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1435-1250</ISSN><JournalIssue CitedMedium="Internet"><Volume>69</Volume><Issue>1</Issue><PubDate><Year>2010</Year><Month>Feb</Month></PubDate></JournalIssue><Title>Zeitschrift fur Rheumatologie</Title><ISOAbbreviation>Z Rheumatol</ISOAbbreviation></Journal><ArticleTitle>[Is bioptic assurance reasonable in patients with Sjögren's syndrome? From focus score to diagnosing vasculitides].</ArticleTitle><Pagination><MedlinePgn>11-8</MedlinePgn></Pagination><ELocationID EIdType="doi" ValidYN="Y">10.1007/s00393-009-0514-7</ELocationID><Abstract><AbstractText>Sjögren's syndrome is an autoimmune disease which targets the salivary and lacrimal glands in particular, causing sicca syndrome. Extraglandular manifestations are often seen. Chronic sialadenitis of the parotid gland is the most common symptom to be assessed for differential diagnosis. Common HE and Giemsa slices are histopathologically examined and graduated for lymphocyte infiltration (focus): grade 0: absent, grade 1: slight, grade 2: moderate non-focal infiltration, grade 3: 1 focus (> or =50 lymphocytes) per 4 mm2, grade 4: >1 focus. Grade 3 infiltrates correspond to a focus score of 1, which is one of four disease-classifying criteria acknowledged for diagnosis. Bioptic examination is also performed to rule out different (non-) immunologic sialadenitises, such as the necrotizing or epithelioid-like form (in sarcoidosis), and the extranodal marginal-zone lymphoma. Extraglandular manifestations of Sjögren's syndrome can also be safely diagnosed by histopathological examination. Emphases lie on vasculitides and myositides. Bioptic work-up, therefore, is not only reasonable but also an essential tool for diagnostics in Sjögren's syndrome.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Krenn</LastName><ForeName>V</ForeName><Initials>V</Initials><AffiliationInfo><Affiliation>Zentrum für Histologie, Zytologie und Molekulare Diagnostik, Max-Planck-Str. 18+20, 54296 Trier. krenn@patho-trier.de</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Jakobs</LastName><ForeName>M</ForeName><Initials>M</Initials></Author><Author ValidYN="Y"><LastName>Kriegsmann</LastName><ForeName>J</ForeName><Initials>J</Initials></Author><Author ValidYN="Y"><LastName>Krukemeyer</LastName><ForeName>M G</ForeName><Initials>MG</Initials></Author><Author ValidYN="Y"><LastName>Rieger</LastName><ForeName>A</ForeName><Initials>A</Initials></Author></AuthorList><Language>ger</Language><PublicationTypeList><PublicationType UI="D004740">English Abstract</PublicationType><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016454">Review</PublicationType></PublicationTypeList><VernacularTitle>Ist eine bioptische Sicherung beim Sjögren-Syndrom sinnvoll? Vom Focus-Score zur Vaskulitisdiagnostik.</VernacularTitle></Article><MedlineJournalInfo><Country>Germany</Country><MedlineTA>Z Rheumatol</MedlineTA><NlmUniqueID>0414162</NlmUniqueID><ISSNLinking>0340-1855</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D001323">Autoantibodies</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D001323" MajorTopicYN="N">Autoantibodies</DescriptorName><QualifierName UI="Q000097" MajorTopicYN="N">blood</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D001706" MajorTopicYN="N">Biopsy</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D002196" MajorTopicYN="N">Capillaries</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D003937" MajorTopicYN="N">Diagnosis, Differential</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007638" MajorTopicYN="N">Keratoconjunctivitis Sicca</DescriptorName><QualifierName UI="Q000145" MajorTopicYN="N">classification</QualifierName><QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008218" MajorTopicYN="N">Lymphocytosis</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D008854" MajorTopicYN="N">Microscopy, Electron</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D018482" MajorTopicYN="N">Muscle, Skeletal</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D009220" MajorTopicYN="N">Myositis</DescriptorName><QualifierName UI="Q000145" MajorTopicYN="N">classification</QualifierName><QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D010306" MajorTopicYN="N">Parotid Gland</DescriptorName><QualifierName UI="Q000473" MajorTopicYN="N">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012793" MajorTopicYN="N">Sialadenitis</DescriptorName><QualifierName UI="Q000145" MajorTopicYN="N">classification</QualifierName><QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D012859" MajorTopicYN="N">Sjogren's Syndrome</DescriptorName><QualifierName UI="Q000145" MajorTopicYN="N">classification</QualifierName><QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D014657" MajorTopicYN="N">Vasculitis</DescriptorName><QualifierName UI="Q000145" MajorTopicYN="N">classification</QualifierName><QualifierName UI="Q000473" MajorTopicYN="Y">pathology</QualifierName></MeshHeading></MeshHeadingList><NumberOfReferences>32</NumberOfReferences></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="entrez"><Year>2009</Year><Month>12</Month><Day>10</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2009</Year><Month>12</Month><Day>10</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2010</Year><Month>5</Month><Day>6</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">19997922</ArticleId><ArticleId IdType="doi">10.1007/s00393-009-0514-7</ArticleId></ArticleIdList></PubmedData></pubmed></record>Pour manipuler ce document sous Unix (Dilib)
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