Safety of symptom-limited exercise testing in a big cohort of a modern ICD population.
Identifieur interne : 000183 ( PubMed/Corpus ); précédent : 000182; suivant : 000184Safety of symptom-limited exercise testing in a big cohort of a modern ICD population.
Auteurs : Frederik Voss ; Melanie Schueler ; Michael Lauterbach ; Alexander Bauer ; Hugo A. Katus ; Ruediger BeckerSource :
- Clinical research in cardiology : official journal of the German Cardiac Society [ 1861-0692 ] ; 2016.
English descriptors
- KwdEn :
- MESH :
- adverse effects : Exercise Test.
- complications : Atrial Fibrillation.
- methods : Exercise Test.
- physiopathology : Heart Failure.
- therapy : Heart Failure.
- Aged, Defibrillators, Implantable, Female, Humans, Male, Middle Aged.
Abstract
Exercise may predispose to ventricular arrhythmias especially in patients with congestive heart failure. As therapy with implanted cardioverter-defibrillators (ICDs) has become standard medical care, there is an emerging number of exercise tests that need to be performed in patients with ICDs. In contrast, little is known about the safety of symptom-limited exercise testing in these patients.
DOI: 10.1007/s00392-015-0885-5
PubMed: 26123830
Links to Exploration step
pubmed:26123830Le document en format XML
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<author><name sortKey="Voss, Frederik" sort="Voss, Frederik" uniqKey="Voss F" first="Frederik" last="Voss">Frederik Voss</name>
<affiliation><nlm:affiliation>Department of Cardiology, Krankenhaus der Barmherzigen Brueder Trier, Nordallee 1, 54290, Trier, Germany. f.voss@bk-trier.de.</nlm:affiliation>
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<author><name sortKey="Schueler, Melanie" sort="Schueler, Melanie" uniqKey="Schueler M" first="Melanie" last="Schueler">Melanie Schueler</name>
<affiliation><nlm:affiliation>Department of Cardiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.</nlm:affiliation>
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<author><name sortKey="Lauterbach, Michael" sort="Lauterbach, Michael" uniqKey="Lauterbach M" first="Michael" last="Lauterbach">Michael Lauterbach</name>
<affiliation><nlm:affiliation>Department of Cardiology, Krankenhaus der Barmherzigen Brueder Trier, Nordallee 1, 54290, Trier, Germany.</nlm:affiliation>
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<author><name sortKey="Bauer, Alexander" sort="Bauer, Alexander" uniqKey="Bauer A" first="Alexander" last="Bauer">Alexander Bauer</name>
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<author><name sortKey="Katus, Hugo A" sort="Katus, Hugo A" uniqKey="Katus H" first="Hugo A" last="Katus">Hugo A. Katus</name>
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<author><name sortKey="Becker, Ruediger" sort="Becker, Ruediger" uniqKey="Becker R" first="Ruediger" last="Becker">Ruediger Becker</name>
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<author><name sortKey="Lauterbach, Michael" sort="Lauterbach, Michael" uniqKey="Lauterbach M" first="Michael" last="Lauterbach">Michael Lauterbach</name>
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<term>Atrial Fibrillation (complications)</term>
<term>Defibrillators, Implantable</term>
<term>Exercise Test (adverse effects)</term>
<term>Exercise Test (methods)</term>
<term>Female</term>
<term>Heart Failure (physiopathology)</term>
<term>Heart Failure (therapy)</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
</keywords>
<keywords scheme="MESH" qualifier="adverse effects" xml:lang="en"><term>Exercise Test</term>
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<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Atrial Fibrillation</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Exercise Test</term>
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<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en"><term>Heart Failure</term>
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<keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Heart Failure</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Aged</term>
<term>Defibrillators, Implantable</term>
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<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
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<front><div type="abstract" xml:lang="en">Exercise may predispose to ventricular arrhythmias especially in patients with congestive heart failure. As therapy with implanted cardioverter-defibrillators (ICDs) has become standard medical care, there is an emerging number of exercise tests that need to be performed in patients with ICDs. In contrast, little is known about the safety of symptom-limited exercise testing in these patients.</div>
</front>
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<Title>Clinical research in cardiology : official journal of the German Cardiac Society</Title>
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<ArticleTitle>Safety of symptom-limited exercise testing in a big cohort of a modern ICD population.</ArticleTitle>
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<Abstract><AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Exercise may predispose to ventricular arrhythmias especially in patients with congestive heart failure. As therapy with implanted cardioverter-defibrillators (ICDs) has become standard medical care, there is an emerging number of exercise tests that need to be performed in patients with ICDs. In contrast, little is known about the safety of symptom-limited exercise testing in these patients.</AbstractText>
<AbstractText Label="METHODS AND RESULTS" NlmCategory="RESULTS">400 ICD patients performed symptom-limited exercise treadmill testing. 200 patients performed a ramp protocol with an initial workload of 0 W increased by 15 W every minute. Another 200 ICD patients did a slightly modified ramp protocol with again an initial workload of 0 W but with an increased capacity of 15 W every 2 min. The study population consists mainly of patients with ischemic (63%) and non-ischemic (34%) heart disease. Atrial fibrillation was present in 16% of the subjects. The mean ejection fraction was 28 ± 8, and 78% of the patients had an ejection fraction below 30%. In this cohort of patients, no sustained ventricular arrhythmias and no deaths occurred during or after exercise testing. No inappropriate shock delivery was observed. The modified ramp protocol resulted in a prolonged exercise time with equal exercise capacity but does not result in an enhanced susceptibility for ventricular arrhythmias.</AbstractText>
<AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">Symptom-limited exercise treadmill testing in heart failure patients with ICDs is a safe procedure. The use of a ramp protocol is sufficient in terms of safety and is easy to perform in general practice. The exercise duration in heart failure patients with ICDs does not predict serious adverse events.</AbstractText>
</Abstract>
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